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Détail de l'auteur
Auteur Elizabeth M. LENNON |
Documents disponibles écrits par cet auteur (2)
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Neonatal Brainstem Function and 4-Month Arousal-Modulated Attention Are Jointly Associated With Autism / Ira L. COHEN in Autism Research, 6-1 (February 2013)
[article]
Titre : Neonatal Brainstem Function and 4-Month Arousal-Modulated Attention Are Jointly Associated With Autism Type de document : Texte imprimé et/ou numérique Auteurs : Ira L. COHEN, Auteur ; Judith M. GARDNER, Auteur ; Bernard Z. KARMEL, Auteur ; Ha T. T. PHAN, Auteur ; Phyllis KITTLER, Auteur ; Tina Rovito GOMEZ, Auteur ; Maripaz G. GONZALEZ, Auteur ; Elizabeth M. LENNON, Auteur ; Santosh PARAB, Auteur ; Anthony BARONE, Auteur Année de publication : 2013 Article en page(s) : p.11-22 Langues : Anglais (eng) Mots-clés : auditory brainstem response infancy attention arousal repetitive and ritualistic behaviors autism spectrum disorder Index. décimale : PER Périodiques Résumé : The authors evaluated the contribution of initially abnormal neonatal auditory brainstem responses (ABRs) and 4-month arousal-modulated attention visual preference to later autism spectrum disorder (ASD) behaviors in neonatal intensive care unit (NICU) graduates. A longitudinal study design was used to compare NICU graduates with normal ABRs (n?=?28) to those with initially abnormal ABRs (n?=?46) that later resolved. At 4 months postterm age, visual preference (measured after feeding) for a random check pattern flashing at 1, 3, or 8?Hz and gestational age (GA) served as additional predictors. Outcome measures were PDD Behavior Inventory (PDDBI) scores at 3.4 years (standard deviation?=?1.2), and developmental quotients (DQ) obtained around the same age with the Griffiths Mental Development Scales (GMDS). Preferences for higher rates of stimulation at 4 months were highly correlated with PDDBI scores (all P-values??0.01) and the GMDS Hearing and Speech DQ, but only in those with initially abnormal ABRs. Effects were strongest for a PDDBI social competence measure most associated with a diagnosis of autism. For those with abnormal ABRs, increases in preference for higher rates of stimulation as infants were linked to nonlinear increases in severity of ASD at 3 years and to an ASD diagnosis. Abnormal ABRs were associated with later reports of repetitive and ritualistic behaviors irrespective of 4-month preference for stimulation. The joint occurrence of initially abnormal neonatal ABRs and preference for more stimulation at 4 months, both indices of early brainstem dysfunction, may be a marker for the development of autism in this cohort. En ligne : http://dx.doi.org/10.1002/aur.1259 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192
in Autism Research > 6-1 (February 2013) . - p.11-22[article] Neonatal Brainstem Function and 4-Month Arousal-Modulated Attention Are Jointly Associated With Autism [Texte imprimé et/ou numérique] / Ira L. COHEN, Auteur ; Judith M. GARDNER, Auteur ; Bernard Z. KARMEL, Auteur ; Ha T. T. PHAN, Auteur ; Phyllis KITTLER, Auteur ; Tina Rovito GOMEZ, Auteur ; Maripaz G. GONZALEZ, Auteur ; Elizabeth M. LENNON, Auteur ; Santosh PARAB, Auteur ; Anthony BARONE, Auteur . - 2013 . - p.11-22.
Langues : Anglais (eng)
in Autism Research > 6-1 (February 2013) . - p.11-22
Mots-clés : auditory brainstem response infancy attention arousal repetitive and ritualistic behaviors autism spectrum disorder Index. décimale : PER Périodiques Résumé : The authors evaluated the contribution of initially abnormal neonatal auditory brainstem responses (ABRs) and 4-month arousal-modulated attention visual preference to later autism spectrum disorder (ASD) behaviors in neonatal intensive care unit (NICU) graduates. A longitudinal study design was used to compare NICU graduates with normal ABRs (n?=?28) to those with initially abnormal ABRs (n?=?46) that later resolved. At 4 months postterm age, visual preference (measured after feeding) for a random check pattern flashing at 1, 3, or 8?Hz and gestational age (GA) served as additional predictors. Outcome measures were PDD Behavior Inventory (PDDBI) scores at 3.4 years (standard deviation?=?1.2), and developmental quotients (DQ) obtained around the same age with the Griffiths Mental Development Scales (GMDS). Preferences for higher rates of stimulation at 4 months were highly correlated with PDDBI scores (all P-values??0.01) and the GMDS Hearing and Speech DQ, but only in those with initially abnormal ABRs. Effects were strongest for a PDDBI social competence measure most associated with a diagnosis of autism. For those with abnormal ABRs, increases in preference for higher rates of stimulation as infants were linked to nonlinear increases in severity of ASD at 3 years and to an ASD diagnosis. Abnormal ABRs were associated with later reports of repetitive and ritualistic behaviors irrespective of 4-month preference for stimulation. The joint occurrence of initially abnormal neonatal ABRs and preference for more stimulation at 4 months, both indices of early brainstem dysfunction, may be a marker for the development of autism in this cohort. En ligne : http://dx.doi.org/10.1002/aur.1259 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192 Parent PDD Behavior Inventory Profiles of Young Children Classified According to Autism Diagnostic Observation Schedule-Generic and Autism Diagnostic Interview-Revised Criteria / Ira L. COHEN in Journal of Autism and Developmental Disorders, 40-2 (February 2010)
[article]
Titre : Parent PDD Behavior Inventory Profiles of Young Children Classified According to Autism Diagnostic Observation Schedule-Generic and Autism Diagnostic Interview-Revised Criteria Type de document : Texte imprimé et/ou numérique Auteurs : Ira L. COHEN, Auteur ; Tina Rovito GOMEZ, Auteur ; Maripaz G. GONZALEZ, Auteur ; Elizabeth M. LENNON, Auteur ; Bernard Z. KARMEL, Auteur ; Judith M. GARDNER, Auteur Année de publication : 2010 Article en page(s) : p.246-254 Langues : Anglais (eng) Mots-clés : Autism Assessment Diagnosis Rating-scales Index. décimale : PER Périodiques Résumé : Quantitative variations in score profiles from the parent version of the PDD Behavior Inventory (PDDBI) were examined in young Autism and PDD-NOS groups defined by ADOS-G and ADI-R criteria, relative to a not spectrum (NS) group of similar age. Both the Autism and the PDD-NOS group profiles markedly differed from the NS group. The most sensitive measures of group differences were those domain and composite scores that assessed social communication competence, as well as the overall Autism Composite score. Sensitivity, specificity and positive and negative predictability measures were quite good for these measures. It was concluded that the PDDBI is useful in assisting in the differential diagnosis of autism spectrum disorder. En ligne : http://dx.doi.org/10.1007/s10803-009-0863-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=965
in Journal of Autism and Developmental Disorders > 40-2 (February 2010) . - p.246-254[article] Parent PDD Behavior Inventory Profiles of Young Children Classified According to Autism Diagnostic Observation Schedule-Generic and Autism Diagnostic Interview-Revised Criteria [Texte imprimé et/ou numérique] / Ira L. COHEN, Auteur ; Tina Rovito GOMEZ, Auteur ; Maripaz G. GONZALEZ, Auteur ; Elizabeth M. LENNON, Auteur ; Bernard Z. KARMEL, Auteur ; Judith M. GARDNER, Auteur . - 2010 . - p.246-254.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 40-2 (February 2010) . - p.246-254
Mots-clés : Autism Assessment Diagnosis Rating-scales Index. décimale : PER Périodiques Résumé : Quantitative variations in score profiles from the parent version of the PDD Behavior Inventory (PDDBI) were examined in young Autism and PDD-NOS groups defined by ADOS-G and ADI-R criteria, relative to a not spectrum (NS) group of similar age. Both the Autism and the PDD-NOS group profiles markedly differed from the NS group. The most sensitive measures of group differences were those domain and composite scores that assessed social communication competence, as well as the overall Autism Composite score. Sensitivity, specificity and positive and negative predictability measures were quite good for these measures. It was concluded that the PDDBI is useful in assisting in the differential diagnosis of autism spectrum disorder. En ligne : http://dx.doi.org/10.1007/s10803-009-0863-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=965