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Auteur Marie-Christine PICOT |
Documents disponibles écrits par cet auteur (9)
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Determinants of Inclusion in Mainstream School for Children with Autism Spectrum Disorders from the EpiTED Study: A 10-Year Follow-up Cohort / Charlotte LAFONT in Journal of Autism and Developmental Disorders, 53-1 (January 2023)
[article]
Titre : Determinants of Inclusion in Mainstream School for Children with Autism Spectrum Disorders from the EpiTED Study: A 10-Year Follow-up Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Charlotte LAFONT, Auteur ; Henri PANJO, Auteur ; Cécile MICHELON, Auteur ; Bruno FALISSARD, Auteur ; Mario SPERANZA, Auteur ; Marie-Christine PICOT, Auteur ; Amaria BAGHDADLI, Auteur ; Alexandra ROUQUETTE, Auteur Article en page(s) : p.121-131 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Inclusion of students with Autism Spectrum Disorder (ASD) in mainstream schools has a positive impact on their social and daily living behaviors. Our objective was to identify clinical and socio-demographic variables promoting or limiting inclusion in mainstream school through childhood and adolescence. The EpiTED study is a long-term, prospective, multicenter cohort of 281 ASD children included before the age of 7, with a 10-year follow-up in France. Variables significantly linked to inclusion in mainstream school were identified using a mixed-effect logistic regression model: greater autonomy [OR=1.45 (1.29 “1.63)], lesser symptom severity [OR=0.96 (0.92 “0.99)] and fewer siblings [OR=0.86 (0.75 “0.99)]. In the multivariate model, the probability for a child of being included in mainstream school decreased over time [OR=0.91 (0.85 “0.97)], i.e. with age. En ligne : https://doi.org/10.1007/s10803-021-05404-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493
in Journal of Autism and Developmental Disorders > 53-1 (January 2023) . - p.121-131[article] Determinants of Inclusion in Mainstream School for Children with Autism Spectrum Disorders from the EpiTED Study: A 10-Year Follow-up Cohort [Texte imprimé et/ou numérique] / Charlotte LAFONT, Auteur ; Henri PANJO, Auteur ; Cécile MICHELON, Auteur ; Bruno FALISSARD, Auteur ; Mario SPERANZA, Auteur ; Marie-Christine PICOT, Auteur ; Amaria BAGHDADLI, Auteur ; Alexandra ROUQUETTE, Auteur . - p.121-131.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 53-1 (January 2023) . - p.121-131
Index. décimale : PER Périodiques Résumé : Inclusion of students with Autism Spectrum Disorder (ASD) in mainstream schools has a positive impact on their social and daily living behaviors. Our objective was to identify clinical and socio-demographic variables promoting or limiting inclusion in mainstream school through childhood and adolescence. The EpiTED study is a long-term, prospective, multicenter cohort of 281 ASD children included before the age of 7, with a 10-year follow-up in France. Variables significantly linked to inclusion in mainstream school were identified using a mixed-effect logistic regression model: greater autonomy [OR=1.45 (1.29 “1.63)], lesser symptom severity [OR=0.96 (0.92 “0.99)] and fewer siblings [OR=0.86 (0.75 “0.99)]. In the multivariate model, the probability for a child of being included in mainstream school decreased over time [OR=0.91 (0.85 “0.97)], i.e. with age. En ligne : https://doi.org/10.1007/s10803-021-05404-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493 Developmental Trajectories of Adaptive Behaviors from Early Childhood to Adolescence in a Cohort of 152 Children with Autism Spectrum Disorders / Amaria BAGHDADLI in Journal of Autism and Developmental Disorders, 42-7 (July 2012)
[article]
Titre : Developmental Trajectories of Adaptive Behaviors from Early Childhood to Adolescence in a Cohort of 152 Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Amaria BAGHDADLI, Auteur ; Brigitte ASSOULINE, Auteur ; Sandrine SONIE, Auteur ; Eric PERNON, Auteur ; Céline DARROU, Auteur ; Cécile MICHELON, Auteur ; Marie-Christine PICOT, Auteur ; Charles AUSSILLOUX, Auteur ; René PRY, Auteur Année de publication : 2012 Article en page(s) : p.1314-1325 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Developmental trajectory Adaptive behaviors Cohort Index. décimale : PER Périodiques Résumé : This study examines change in 152 children over an almost 10-year period (T1: 4.9 (±1.3) years; T2: 8.1 (±1.3) years; T3: 15(±1.6) years) using a group-based, semi-parametric method in order to identify distinct developmental trajectories. Important deficits remain at adolescence in the adaptive abilities of children with Autism spectrum disorders, but changes in adaptive skills show two distinct growth rates. The univariate analysis reveals that low growth trajectories for both social and communication outcome are associated with the following characteristics at age 5: low cognitive and language skills, presence of epilepsy, and severity of autism. The multivariate analysis confirms that risk factors at age 5, were low language and severity of autism for both social and communication outcomes 10 years later, and that hours of early intervention was protective factor for communication. En ligne : http://dx.doi.org/10.1007/s10803-011-1357-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166
in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1314-1325[article] Developmental Trajectories of Adaptive Behaviors from Early Childhood to Adolescence in a Cohort of 152 Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Amaria BAGHDADLI, Auteur ; Brigitte ASSOULINE, Auteur ; Sandrine SONIE, Auteur ; Eric PERNON, Auteur ; Céline DARROU, Auteur ; Cécile MICHELON, Auteur ; Marie-Christine PICOT, Auteur ; Charles AUSSILLOUX, Auteur ; René PRY, Auteur . - 2012 . - p.1314-1325.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1314-1325
Mots-clés : Autism spectrum disorders Developmental trajectory Adaptive behaviors Cohort Index. décimale : PER Périodiques Résumé : This study examines change in 152 children over an almost 10-year period (T1: 4.9 (±1.3) years; T2: 8.1 (±1.3) years; T3: 15(±1.6) years) using a group-based, semi-parametric method in order to identify distinct developmental trajectories. Important deficits remain at adolescence in the adaptive abilities of children with Autism spectrum disorders, but changes in adaptive skills show two distinct growth rates. The univariate analysis reveals that low growth trajectories for both social and communication outcome are associated with the following characteristics at age 5: low cognitive and language skills, presence of epilepsy, and severity of autism. The multivariate analysis confirms that risk factors at age 5, were low language and severity of autism for both social and communication outcomes 10 years later, and that hours of early intervention was protective factor for communication. En ligne : http://dx.doi.org/10.1007/s10803-011-1357-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166 Factors associated with age of diagnosis in children with autism spectrum disorders: Report from a French cohort / Cécile RATTAZ in Autism, 26-8 (November 2022)
[article]
Titre : Factors associated with age of diagnosis in children with autism spectrum disorders: Report from a French cohort Type de document : Texte imprimé et/ou numérique Auteurs : Cécile RATTAZ, Auteur ; Julie LOUBERSAC, Auteur ; Cécile MICHELON, Auteur ; Marie-Maude GEOFFRAY, Auteur ; Marie-Christine PICOT, Auteur ; Kerim M. MUNIR, Auteur ; Amaria BAGHDADLI, Auteur Article en page(s) : p.2108-2116 Langues : Anglais (eng) Mots-clés : Child Adolescent Humans Child, Preschool Autism Spectrum Disorder/diagnosis/epidemiology/complications Cohort Studies Intellectual Disability/complications Early Diagnosis Social Class ELENA cohort age of diagnosis autism spectrum disorder children Index. décimale : PER Périodiques Résumé : Autism spectrum disorder is an early onset neurodevelopmental disorder and diagnosis can be made as early as 18 months of age. Early diagnosis of autism spectrum disorder is critical as it leads to early intervention. Age of autism spectrum disorder diagnosis has been linked to the child profile as autism spectrum disorder is characterized by strong heterogeneity, but is also influenced by socio-economic factors. There is paucity of data on age of diagnosis of autism spectrum disorder in France. We therefore examined the age of autism spectrum disorder diagnosis in 554 children and adolescents enrolled in the ELENA cohort study with respect to the influences of child profile, family antecedents, and socio-economic factors. The mean age of diagnosis was 4.9 years (Â+2.8 years). Early diagnosis, before 3 years of age, was related to the co-occurrence of intellectual disability, higher autism spectrum disorder symptom severity, and lower communicative abilities. Children in low socio-economic status families tended to have an earlier diagnosis, but these children also had greater degree of intellectual impairment compared to children in high socio-economic status families. The age of autism spectrum disorder diagnosis was not associated with the presence of an older sibling with autism spectrum disorder. The observed current trend of an inverse relationship between socio-economic status and age of diagnosis of autism spectrum disorder suggests equitable access to autism spectrum disorder services in France where health coverage is universal and free. Better screening of more subtle/less severe forms of autism spectrum disorder is needed, as well as further assessment of the link between the co-occurrence of autism spectrum disorder and intellectual impairment in children in lower socio-economic status families. En ligne : http://dx.doi.org/10.1177/13623613221077724 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism > 26-8 (November 2022) . - p.2108-2116[article] Factors associated with age of diagnosis in children with autism spectrum disorders: Report from a French cohort [Texte imprimé et/ou numérique] / Cécile RATTAZ, Auteur ; Julie LOUBERSAC, Auteur ; Cécile MICHELON, Auteur ; Marie-Maude GEOFFRAY, Auteur ; Marie-Christine PICOT, Auteur ; Kerim M. MUNIR, Auteur ; Amaria BAGHDADLI, Auteur . - p.2108-2116.
Langues : Anglais (eng)
in Autism > 26-8 (November 2022) . - p.2108-2116
Mots-clés : Child Adolescent Humans Child, Preschool Autism Spectrum Disorder/diagnosis/epidemiology/complications Cohort Studies Intellectual Disability/complications Early Diagnosis Social Class ELENA cohort age of diagnosis autism spectrum disorder children Index. décimale : PER Périodiques Résumé : Autism spectrum disorder is an early onset neurodevelopmental disorder and diagnosis can be made as early as 18 months of age. Early diagnosis of autism spectrum disorder is critical as it leads to early intervention. Age of autism spectrum disorder diagnosis has been linked to the child profile as autism spectrum disorder is characterized by strong heterogeneity, but is also influenced by socio-economic factors. There is paucity of data on age of diagnosis of autism spectrum disorder in France. We therefore examined the age of autism spectrum disorder diagnosis in 554 children and adolescents enrolled in the ELENA cohort study with respect to the influences of child profile, family antecedents, and socio-economic factors. The mean age of diagnosis was 4.9 years (Â+2.8 years). Early diagnosis, before 3 years of age, was related to the co-occurrence of intellectual disability, higher autism spectrum disorder symptom severity, and lower communicative abilities. Children in low socio-economic status families tended to have an earlier diagnosis, but these children also had greater degree of intellectual impairment compared to children in high socio-economic status families. The age of autism spectrum disorder diagnosis was not associated with the presence of an older sibling with autism spectrum disorder. The observed current trend of an inverse relationship between socio-economic status and age of diagnosis of autism spectrum disorder suggests equitable access to autism spectrum disorder services in France where health coverage is universal and free. Better screening of more subtle/less severe forms of autism spectrum disorder is needed, as well as further assessment of the link between the co-occurrence of autism spectrum disorder and intellectual impairment in children in lower socio-economic status families. En ligne : http://dx.doi.org/10.1177/13623613221077724 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Multimorbidity patterns and subgroups among autistic adults with intellectual disability: Results from the EFAAR study / Stéphanie MIOT in Autism, 27-3 (April 2023)
[article]
Titre : Multimorbidity patterns and subgroups among autistic adults with intellectual disability: Results from the EFAAR study Type de document : Texte imprimé et/ou numérique Auteurs : Stéphanie MIOT, Auteur ; Raphaël CHANCEL, Auteur ; Marianne PERIES, Auteur ; Sophie CREPIAT, Auteur ; Sylvie COUDERC, Auteur ; Eric PERNON, Auteur ; Marie-Christine PICOT, Auteur ; Véronique GONNIER, Auteur ; Claude JEANDEL, Auteur ; Hubert BLAIN, Auteur ; Amaria BAGHDADLI, Auteur Article en page(s) : p.762-777 Langues : Anglais (eng) Mots-clés : adults,autism spectrum disorder,intellectual disability,multimorbidity Index. décimale : PER Périodiques Résumé : Multimorbidity, defined as having two or more chronic health conditions, is associated with elevated polypharmacy and mortality. Autism spectrum disorder is a whole-body chronic health condition in which comorbidities - in particular co-occurring intellectual disability - contribute to high clinical heterogeneity, polypharmacy and premature mortality. We aimed to determine specific multimorbidity patterns among autism spectrum disorder?+?intellectual disability adults, and to identify participants' subgroups based on multimorbidity features. We used baseline examination data from a previous exploratory prospective multicentric study that included 63 autism spectrum disorder?+?intellectual disability adults. Multimorbidity patterns and subgroups were determined using clustering approaches. We observed 84.1% multimorbidity, significantly associated with age. We identified a dominant multimorbidity pattern, combining immune dysfunction, gastrointestinal disorders, neurological, and joint diseases. Four participants' subgroups could be distinguished by multimorbidity, autonomy and polypharmacy. Two clusters were distinguished by the prevalence and consequences of multimorbidity. One cluster involved women with endocrine disorders. The final cluster was composed of older adults with the lowest autism spectrum disorder severity but greater multimorbidity, including cardiovascular and kidney diseases. Our results support a role for the gut-brain axis in the pathophysiology of autism spectrum disorder?+?intellectual disability multimorbidity. Furthermore, we identified patient subgroups with specific needs, underscoring the importance of a holistic approach for autism spectrum disorder?+?intellectual disability adults.Lay abstractMultimorbidity relates to having multiple chronic health conditions. It is a risk factor for poor health and reduces life expectancy. Autistic people have multiple chronic health conditions and die prematurely, especially if they have an intellectual disability (autism spectrum disorder and intellectual disability). Certain pathophysiological processes observed in autism spectrum disorder are common to those related to the genesis and/or maintenance of multimorbidity. Furthermore, multimorbidity could be helpful in better identifying patient subgroups in autism spectrum disorder. It is therefore essential to better characterize multimorbidity and its consequences in the subgroup of autism spectrum disorder?+?intellectual disability individuals to offer them personalized care. We conducted a preliminary study of 63 autism spectrum disorder?+?intellectual disability adults to classify them according to their multimorbidity and search for a specific combination of chronic health conditions. We observed high and early multimorbidity in this sample and identified four classes of participants, distinguished by their multimorbidity status, independence and number of treatments. In addition, we observed a dominant combination of multimorbidity in our sample, combining immune dysfunction and gastrointestinal disorders, neurological and joint diseases. These findings support the hypothesis that an altered gut-brain relationship is involved in the risk of autism spectrum disorder, its outcome, and its association with chronic health conditions. Although larger studies are needed, our results suggest that subgroups of autism spectrum disorder?+?intellectual disability individuals can be identified based on their multimorbidity and potentially different ageing trajectories. A more comprehensive and personalized approach is needed to reduce the burden of multimorbidity and increase the quality of life and life expectancy in autism spectrum disorder/ intellectual disability. En ligne : https://doi.org/10.1177/13623613221121623 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499
in Autism > 27-3 (April 2023) . - p.762-777[article] Multimorbidity patterns and subgroups among autistic adults with intellectual disability: Results from the EFAAR study [Texte imprimé et/ou numérique] / Stéphanie MIOT, Auteur ; Raphaël CHANCEL, Auteur ; Marianne PERIES, Auteur ; Sophie CREPIAT, Auteur ; Sylvie COUDERC, Auteur ; Eric PERNON, Auteur ; Marie-Christine PICOT, Auteur ; Véronique GONNIER, Auteur ; Claude JEANDEL, Auteur ; Hubert BLAIN, Auteur ; Amaria BAGHDADLI, Auteur . - p.762-777.
Langues : Anglais (eng)
in Autism > 27-3 (April 2023) . - p.762-777
Mots-clés : adults,autism spectrum disorder,intellectual disability,multimorbidity Index. décimale : PER Périodiques Résumé : Multimorbidity, defined as having two or more chronic health conditions, is associated with elevated polypharmacy and mortality. Autism spectrum disorder is a whole-body chronic health condition in which comorbidities - in particular co-occurring intellectual disability - contribute to high clinical heterogeneity, polypharmacy and premature mortality. We aimed to determine specific multimorbidity patterns among autism spectrum disorder?+?intellectual disability adults, and to identify participants' subgroups based on multimorbidity features. We used baseline examination data from a previous exploratory prospective multicentric study that included 63 autism spectrum disorder?+?intellectual disability adults. Multimorbidity patterns and subgroups were determined using clustering approaches. We observed 84.1% multimorbidity, significantly associated with age. We identified a dominant multimorbidity pattern, combining immune dysfunction, gastrointestinal disorders, neurological, and joint diseases. Four participants' subgroups could be distinguished by multimorbidity, autonomy and polypharmacy. Two clusters were distinguished by the prevalence and consequences of multimorbidity. One cluster involved women with endocrine disorders. The final cluster was composed of older adults with the lowest autism spectrum disorder severity but greater multimorbidity, including cardiovascular and kidney diseases. Our results support a role for the gut-brain axis in the pathophysiology of autism spectrum disorder?+?intellectual disability multimorbidity. Furthermore, we identified patient subgroups with specific needs, underscoring the importance of a holistic approach for autism spectrum disorder?+?intellectual disability adults.Lay abstractMultimorbidity relates to having multiple chronic health conditions. It is a risk factor for poor health and reduces life expectancy. Autistic people have multiple chronic health conditions and die prematurely, especially if they have an intellectual disability (autism spectrum disorder and intellectual disability). Certain pathophysiological processes observed in autism spectrum disorder are common to those related to the genesis and/or maintenance of multimorbidity. Furthermore, multimorbidity could be helpful in better identifying patient subgroups in autism spectrum disorder. It is therefore essential to better characterize multimorbidity and its consequences in the subgroup of autism spectrum disorder?+?intellectual disability individuals to offer them personalized care. We conducted a preliminary study of 63 autism spectrum disorder?+?intellectual disability adults to classify them according to their multimorbidity and search for a specific combination of chronic health conditions. We observed high and early multimorbidity in this sample and identified four classes of participants, distinguished by their multimorbidity status, independence and number of treatments. In addition, we observed a dominant combination of multimorbidity in our sample, combining immune dysfunction and gastrointestinal disorders, neurological and joint diseases. These findings support the hypothesis that an altered gut-brain relationship is involved in the risk of autism spectrum disorder, its outcome, and its association with chronic health conditions. Although larger studies are needed, our results suggest that subgroups of autism spectrum disorder?+?intellectual disability individuals can be identified based on their multimorbidity and potentially different ageing trajectories. A more comprehensive and personalized approach is needed to reduce the burden of multimorbidity and increase the quality of life and life expectancy in autism spectrum disorder/ intellectual disability. En ligne : https://doi.org/10.1177/13623613221121623 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 School Inclusion in Children and Adolescents with Autism Spectrum Disorders in France: Report from the ELENA French Cohort Study / Cécile RATTAZ in Journal of Autism and Developmental Disorders, 50-2 (February 2020)
[article]
Titre : School Inclusion in Children and Adolescents with Autism Spectrum Disorders in France: Report from the ELENA French Cohort Study Type de document : Texte imprimé et/ou numérique Auteurs : Cécile RATTAZ, Auteur ; Kerim M. MUNIR, Auteur ; Cécile MICHELON, Auteur ; Marie-Christine PICOT, Auteur ; Amaria BAGHDADLI, Auteur Article en page(s) : p.455-466 Langues : Anglais (eng) Mots-clés : Asd Cohort France School duration School inclusion Index. décimale : PER Périodiques Résumé : Children and adolescents with ASD are increasingly included in regular school settings, however little is known about how placement decisions are made. In the present study, we examined the types and duration of school attendance among children and adolescents in the ELENA Cohort, a multi-center study of children and adolescents with ASD, ages 2-16 years, in France. Results showed that 88% of subjects were attending school and that children and adolescents with more severe adaptive and cognitive deficits were less likely to attend school. The results provide a topography on school inclusion and ASD in France. Challenging behaviors and sensory processing difficulties were associated with partial-inclusion; and co-occurring anxiety symptoms were associated with inclusion on a full-time basis. En ligne : http://dx.doi.org/10.1007/s10803-019-04273-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416
in Journal of Autism and Developmental Disorders > 50-2 (February 2020) . - p.455-466[article] School Inclusion in Children and Adolescents with Autism Spectrum Disorders in France: Report from the ELENA French Cohort Study [Texte imprimé et/ou numérique] / Cécile RATTAZ, Auteur ; Kerim M. MUNIR, Auteur ; Cécile MICHELON, Auteur ; Marie-Christine PICOT, Auteur ; Amaria BAGHDADLI, Auteur . - p.455-466.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 50-2 (February 2020) . - p.455-466
Mots-clés : Asd Cohort France School duration School inclusion Index. décimale : PER Périodiques Résumé : Children and adolescents with ASD are increasingly included in regular school settings, however little is known about how placement decisions are made. In the present study, we examined the types and duration of school attendance among children and adolescents in the ELENA Cohort, a multi-center study of children and adolescents with ASD, ages 2-16 years, in France. Results showed that 88% of subjects were attending school and that children and adolescents with more severe adaptive and cognitive deficits were less likely to attend school. The results provide a topography on school inclusion and ASD in France. Challenging behaviors and sensory processing difficulties were associated with partial-inclusion; and co-occurring anxiety symptoms were associated with inclusion on a full-time basis. En ligne : http://dx.doi.org/10.1007/s10803-019-04273-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416 SRS-2 : Echelle de réciprocité sociale / John N. CONSTANTINO
PermalinkThe French Version of the Revised Ritvo Autism and Asperger Diagnostic Scale: A Psychometric Validation and Diagnostic Accuracy Study / Marie-Christine PICOT in Journal of Autism and Developmental Disorders, 51-1 (January 2021)
PermalinkThe Impact of Atypical Sensory Processing on Adaptive Functioning and Maladaptive Behaviors in Autism Spectrum Disorder During Childhood: Results From the ELENA Cohort / Florine DELLAPIAZZA in Journal of Autism and Developmental Disorders, 50-6 (June 2020)
PermalinkWISC-V Profiles and Their Correlates in Children with Autism Spectrum Disorder without Intellectual Developmental Disorder: Report from the ELENA Cohort / Lee AUDRAS-TORRENT in Autism Research, 14-5 (May 2021)
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