Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur Amy E. WEST |
Documents disponibles écrits par cet auteur (1)
Faire une suggestion Affiner la recherche
Cognitive dysfunction is worse among pediatric patients with bipolar disorder Type I than Type II / Lindsay S. SCHENKEL in Journal of Child Psychology and Psychiatry, 53-7 (July 2012)
[article]
Titre : Cognitive dysfunction is worse among pediatric patients with bipolar disorder Type I than Type II Type de document : Texte imprimé et/ou numérique Auteurs : Lindsay S. SCHENKEL, Auteur ; Amy E. WEST, Auteur ; Rachel H. JACOBS, Auteur ; John A. SWEENEY, Auteur ; Mani N. PAVULURI, Auteur Année de publication : 2012 Article en page(s) : p.775-781 Langues : Anglais (eng) Mots-clés : Pediatric bipolar disorder neurocognitive function bipolar I disorder bipolar II disorder clinical subtypes Index. décimale : PER Périodiques Résumé : Background: Impaired profiles of neurocognitive function have been consistently demonstrated among pediatric patients with bipolar disorder (BD), and may aid in the identification of endophenotypes across subtypes of the disorder. This study aims to determine phenotypic cognitive profiles of patients with BD Type I and II.
Methods: Subjects (N = 79) consisted of BD I (n = 27) and BD II (n = 19) patients and demographic and intellectually matched healthy controls (HC; n = 33) that completed a battery of neurocognitive tasks.
Results: Bipolar disorder Type I patients performed significantly more poorly compared to HC on all domains of cognitive function including attention, executive function, working memory, visual memory, and verbal learning and memory. BD I patients also performed more poorly compared to BD II patients on all domains of cognitive functioning with the exception of working memory, whereas BD II patients did poorly relative to HC only on verbal learning and memory.
Conclusions: Findings from the current study indicate that BD I patients are characterized by more severe cognitive impairment relative to BD II patients who show an intermediate pattern of performance between BD I patients and HC. Verbal learning and memory may effectively differentiate pediatric BD patients and controls, regardless of the subtype of BD, and may serve as a cognitive endophenotype for the disorder. Additionally, these findings move us closer to developing effective cognitive interventions tailored to specific subtypes of pediatric BD patients.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02519.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166
in Journal of Child Psychology and Psychiatry > 53-7 (July 2012) . - p.775-781[article] Cognitive dysfunction is worse among pediatric patients with bipolar disorder Type I than Type II [Texte imprimé et/ou numérique] / Lindsay S. SCHENKEL, Auteur ; Amy E. WEST, Auteur ; Rachel H. JACOBS, Auteur ; John A. SWEENEY, Auteur ; Mani N. PAVULURI, Auteur . - 2012 . - p.775-781.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 53-7 (July 2012) . - p.775-781
Mots-clés : Pediatric bipolar disorder neurocognitive function bipolar I disorder bipolar II disorder clinical subtypes Index. décimale : PER Périodiques Résumé : Background: Impaired profiles of neurocognitive function have been consistently demonstrated among pediatric patients with bipolar disorder (BD), and may aid in the identification of endophenotypes across subtypes of the disorder. This study aims to determine phenotypic cognitive profiles of patients with BD Type I and II.
Methods: Subjects (N = 79) consisted of BD I (n = 27) and BD II (n = 19) patients and demographic and intellectually matched healthy controls (HC; n = 33) that completed a battery of neurocognitive tasks.
Results: Bipolar disorder Type I patients performed significantly more poorly compared to HC on all domains of cognitive function including attention, executive function, working memory, visual memory, and verbal learning and memory. BD I patients also performed more poorly compared to BD II patients on all domains of cognitive functioning with the exception of working memory, whereas BD II patients did poorly relative to HC only on verbal learning and memory.
Conclusions: Findings from the current study indicate that BD I patients are characterized by more severe cognitive impairment relative to BD II patients who show an intermediate pattern of performance between BD I patients and HC. Verbal learning and memory may effectively differentiate pediatric BD patients and controls, regardless of the subtype of BD, and may serve as a cognitive endophenotype for the disorder. Additionally, these findings move us closer to developing effective cognitive interventions tailored to specific subtypes of pediatric BD patients.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02519.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166