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Auteur Katholiki GEORGIADES |
Documents disponibles écrits par cet auteur (7)
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Adolescent females exposed to child maltreatment exhibit atypical EEG coherence and psychiatric impairment: Linking early adversity, the brain, and psychopathology / Vladimir MISKOVIC in Development and Psychopathology, 22-2 (May 2010)
[article]
Titre : Adolescent females exposed to child maltreatment exhibit atypical EEG coherence and psychiatric impairment: Linking early adversity, the brain, and psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Vladimir MISKOVIC, Auteur ; Katholiki GEORGIADES, Auteur ; Michael H. BOYLE, Auteur ; Louis A. SCHMIDT, Auteur ; Harriet L. MACMILLAN, Auteur Année de publication : 2010 Article en page(s) : p.419-432 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Although the relation between child maltreatment and psychiatric impairment is well documented and preliminary evidence has linked child maltreatment with aberrant cortical connectivity of the left hemisphere, no investigations have attempted to examine these relations in the same study. Here, we examined the links among early adversity, brain connectivity, and functional outcomes. We collected resting regional EEG intra- and interhemispheric α-band (7.5–12.5 Hz) coherence and measures of general psychiatric impairment from a cohort of 38 adolescent females exposed to child maltreatment (M age = 14.47) and 24 adolescent females not exposed to child maltreatment (M age = 14.00). Maltreated youths exhibited more left hemisphere EEG coherence than the control youths, suggesting a suboptimal organization of cortical networks. Maltreated participants also showed reduced frontal (anterior) interhemispheric coherence. These differences in brain circuitry remained statistically significant even after controlling for group differences in pubertal status and socioeconomic status. Measures of functional brain connectivity were associated with several subtypes of abuse and neglect. It was important that atypical left hemisphere EEG coherence mediated the effects of child maltreatment on levels of psychiatric impairment. The findings are discussed in the context of models linking early adversity to brain function and psychopathology. En ligne : http://dx.doi.org/10.1017/s0954579410000155 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102
in Development and Psychopathology > 22-2 (May 2010) . - p.419-432[article] Adolescent females exposed to child maltreatment exhibit atypical EEG coherence and psychiatric impairment: Linking early adversity, the brain, and psychopathology [Texte imprimé et/ou numérique] / Vladimir MISKOVIC, Auteur ; Katholiki GEORGIADES, Auteur ; Michael H. BOYLE, Auteur ; Louis A. SCHMIDT, Auteur ; Harriet L. MACMILLAN, Auteur . - 2010 . - p.419-432.
Langues : Anglais (eng)
in Development and Psychopathology > 22-2 (May 2010) . - p.419-432
Index. décimale : PER Périodiques Résumé : Although the relation between child maltreatment and psychiatric impairment is well documented and preliminary evidence has linked child maltreatment with aberrant cortical connectivity of the left hemisphere, no investigations have attempted to examine these relations in the same study. Here, we examined the links among early adversity, brain connectivity, and functional outcomes. We collected resting regional EEG intra- and interhemispheric α-band (7.5–12.5 Hz) coherence and measures of general psychiatric impairment from a cohort of 38 adolescent females exposed to child maltreatment (M age = 14.47) and 24 adolescent females not exposed to child maltreatment (M age = 14.00). Maltreated youths exhibited more left hemisphere EEG coherence than the control youths, suggesting a suboptimal organization of cortical networks. Maltreated participants also showed reduced frontal (anterior) interhemispheric coherence. These differences in brain circuitry remained statistically significant even after controlling for group differences in pubertal status and socioeconomic status. Measures of functional brain connectivity were associated with several subtypes of abuse and neglect. It was important that atypical left hemisphere EEG coherence mediated the effects of child maltreatment on levels of psychiatric impairment. The findings are discussed in the context of models linking early adversity to brain function and psychopathology. En ligne : http://dx.doi.org/10.1017/s0954579410000155 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102 Adolescent tobacco and cannabis use: young adult outcomes from the Ontario Child Health Study / Katholiki GEORGIADES in Journal of Child Psychology and Psychiatry, 48-7 (July 2007)
[article]
Titre : Adolescent tobacco and cannabis use: young adult outcomes from the Ontario Child Health Study Type de document : Texte imprimé et/ou numérique Auteurs : Katholiki GEORGIADES, Auteur ; Michael H. BOYLE, Auteur Année de publication : 2007 Article en page(s) : p.724–731 Langues : Anglais (eng) Mots-clés : Adolescence adulthood tobacco-use cannabis-use longitudinal-studies Index. décimale : PER Périodiques Résumé : Background: This study examines the longitudinal associations between adolescent tobacco and cannabis use and young adult functioning.
Methods: Data for analysis come from the Ontario Child Health Study (OCHS), a prospective study of child health, psychiatric disorder and adolescent substance use in a general population sample that began in 1983, with follow-ups in 1987 and 2001. The sample for analysis includes 1,282 individuals who were between the ages of 12 and 16 years during the original OCHS in 1983 or the first follow-up in 1987 and returned for the 2001 follow-up.
Results: Tobacco use in adolescence and continued use in adulthood is associated with increased risk for poorer functioning across multiple domains, including physical health and life satisfaction (.62 and .66 standard units lower, respectively), depression (Odds Ratio = 3.44), personal income ($7,281 less per year) and years of education (2.29 years lower). Cannabis use is associated with a reduced set of adverse outcomes and the magnitude of the effects is weaker.
Conclusions: The long-term risks associated with adolescent tobacco and cannabis use speak to the importance of prevention and early intervention.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01740.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=142
in Journal of Child Psychology and Psychiatry > 48-7 (July 2007) . - p.724–731[article] Adolescent tobacco and cannabis use: young adult outcomes from the Ontario Child Health Study [Texte imprimé et/ou numérique] / Katholiki GEORGIADES, Auteur ; Michael H. BOYLE, Auteur . - 2007 . - p.724–731.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 48-7 (July 2007) . - p.724–731
Mots-clés : Adolescence adulthood tobacco-use cannabis-use longitudinal-studies Index. décimale : PER Périodiques Résumé : Background: This study examines the longitudinal associations between adolescent tobacco and cannabis use and young adult functioning.
Methods: Data for analysis come from the Ontario Child Health Study (OCHS), a prospective study of child health, psychiatric disorder and adolescent substance use in a general population sample that began in 1983, with follow-ups in 1987 and 2001. The sample for analysis includes 1,282 individuals who were between the ages of 12 and 16 years during the original OCHS in 1983 or the first follow-up in 1987 and returned for the 2001 follow-up.
Results: Tobacco use in adolescence and continued use in adulthood is associated with increased risk for poorer functioning across multiple domains, including physical health and life satisfaction (.62 and .66 standard units lower, respectively), depression (Odds Ratio = 3.44), personal income ($7,281 less per year) and years of education (2.29 years lower). Cannabis use is associated with a reduced set of adverse outcomes and the magnitude of the effects is weaker.
Conclusions: The long-term risks associated with adolescent tobacco and cannabis use speak to the importance of prevention and early intervention.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01740.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=142 Do reciprocal associations exist between social and language pathways in preschoolers with autism spectrum disorders? / Teresa BENNETT in Journal of Child Psychology and Psychiatry, 56-8 (August 2015)
[article]
Titre : Do reciprocal associations exist between social and language pathways in preschoolers with autism spectrum disorders? Type de document : Texte imprimé et/ou numérique Auteurs : Teresa BENNETT, Auteur ; Peter SZATMARI, Auteur ; Katholiki GEORGIADES, Auteur ; Steven HANNA, Auteur ; Magdelena JANUS, Auteur ; Stelios GEORGIADES, Auteur ; Eric DUKU, Auteur ; Susan E. BRYSON, Auteur ; Eric FOMBONNE, Auteur ; Isabel M. SMITH, Auteur ; Pat MIRENDA, Auteur ; Joanne VOLDEN, Auteur ; Charlotte WADDELL, Auteur ; Wendy ROBERTS, Auteur ; Tracy VAILLANCOURT, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Mayada ELSABBAGH, Auteur ; Ann THOMPSON, Auteur ; THE PATHWAYS IN A. S. D. STUDY TEAM,, Auteur Article en page(s) : p.874-883 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder social development language epidemiology reciprocal effects model Index. décimale : PER Périodiques Résumé : Background Differences in how developmental pathways interact dynamically in children with autism spectrum disorder (ASD) likely contribute in important ways to phenotypic heterogeneity. This study aimed to model longitudinal reciprocal associations between social competence (SOC) and language (LANG) pathways in young children with ASD. Methods Data were obtained from 365 participants aged 2–4 years who had recently been diagnosed with an ASD and who were followed over three time points: baseline (time of diagnosis), 6- and 12 months later. Using structural equation modeling, a cross-lagged reciprocal effects model was developed that incorporated auto-regressive (stability) paths for SOC (using the Socialization subscale of the Vineland Adaptive Behavior Scales-2) and LANG (using the Preschool Language Scale-4 Auditory Comprehension subscale). Cross-domain associations included within-time correlations and lagged associations. Results SOC and LANG were highly stable over 12 months. Small reciprocal cross-lagged associations were found across most time points and within-time correlations decreased over time. There were no differences in strength of cross-lagged associations between SOC-LANG and LANG-SOC across time points. Few differences were found between subgroups of children with ASD with and without cognitive impairment. Conclusions Longitudinal reciprocal cross-domain associations between social competence and language were small in this sample of young children with ASD. Instead, a pattern emerged to suggest that the two domains were strongly associated around time of diagnosis in preschoolers with ASD, and then appeared to become more independent over the ensuing 12 months. En ligne : http://dx.doi.org/10.1111/jcpp.12356 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263
in Journal of Child Psychology and Psychiatry > 56-8 (August 2015) . - p.874-883[article] Do reciprocal associations exist between social and language pathways in preschoolers with autism spectrum disorders? [Texte imprimé et/ou numérique] / Teresa BENNETT, Auteur ; Peter SZATMARI, Auteur ; Katholiki GEORGIADES, Auteur ; Steven HANNA, Auteur ; Magdelena JANUS, Auteur ; Stelios GEORGIADES, Auteur ; Eric DUKU, Auteur ; Susan E. BRYSON, Auteur ; Eric FOMBONNE, Auteur ; Isabel M. SMITH, Auteur ; Pat MIRENDA, Auteur ; Joanne VOLDEN, Auteur ; Charlotte WADDELL, Auteur ; Wendy ROBERTS, Auteur ; Tracy VAILLANCOURT, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Mayada ELSABBAGH, Auteur ; Ann THOMPSON, Auteur ; THE PATHWAYS IN A. S. D. STUDY TEAM,, Auteur . - p.874-883.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-8 (August 2015) . - p.874-883
Mots-clés : Autism spectrum disorder social development language epidemiology reciprocal effects model Index. décimale : PER Périodiques Résumé : Background Differences in how developmental pathways interact dynamically in children with autism spectrum disorder (ASD) likely contribute in important ways to phenotypic heterogeneity. This study aimed to model longitudinal reciprocal associations between social competence (SOC) and language (LANG) pathways in young children with ASD. Methods Data were obtained from 365 participants aged 2–4 years who had recently been diagnosed with an ASD and who were followed over three time points: baseline (time of diagnosis), 6- and 12 months later. Using structural equation modeling, a cross-lagged reciprocal effects model was developed that incorporated auto-regressive (stability) paths for SOC (using the Socialization subscale of the Vineland Adaptive Behavior Scales-2) and LANG (using the Preschool Language Scale-4 Auditory Comprehension subscale). Cross-domain associations included within-time correlations and lagged associations. Results SOC and LANG were highly stable over 12 months. Small reciprocal cross-lagged associations were found across most time points and within-time correlations decreased over time. There were no differences in strength of cross-lagged associations between SOC-LANG and LANG-SOC across time points. Few differences were found between subgroups of children with ASD with and without cognitive impairment. Conclusions Longitudinal reciprocal cross-domain associations between social competence and language were small in this sample of young children with ASD. Instead, a pattern emerged to suggest that the two domains were strongly associated around time of diagnosis in preschoolers with ASD, and then appeared to become more independent over the ensuing 12 months. En ligne : http://dx.doi.org/10.1111/jcpp.12356 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263 Influence of reporting effects on the association between maternal depression and child autism spectrum disorder behaviors / Teresa BENNETT in Journal of Child Psychology and Psychiatry, 53-1 (January 2012)
[article]
Titre : Influence of reporting effects on the association between maternal depression and child autism spectrum disorder behaviors Type de document : Texte imprimé et/ou numérique Auteurs : Teresa BENNETT, Auteur ; Michael H. BOYLE, Auteur ; Katholiki GEORGIADES, Auteur ; Stelios GEORGIADES, Auteur ; Ann THOMPSON, Auteur ; Eric DUKU, Auteur ; Susan E. BRYSON, Auteur ; Eric FOMBONNE, Auteur ; Tracy VAILLANCOURT, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Isabel M. SMITH, Auteur ; Pat MIRENDA, Auteur ; Wendy ROBERTS, Auteur ; Joanne VOLDEN, Auteur ; Charlotte WADDELL, Auteur ; THE PATHWAYS IN ASD STUDY TEAM, Auteur ; Peter SZATMARI, Auteur Année de publication : 2012 Article en page(s) : p.89-96 Langues : Anglais (eng) Mots-clés : Autistic disorder Asperger’s disorder methodology maternal depression structural equation modeling Index. décimale : PER Périodiques Résumé : Background: Maximizing measurement accuracy is an important aim in child development assessment and research. Parents are essential informants in the diagnostic process, and past research suggests that certain parental characteristics may influence how they report information about their children. This has not been studied in autism spectrum disorders (ASD) to date. We aimed, therefore, to investigate the possible effect that maternal depression might have on a mother’s reports of her child’s ASD behaviors. Using structural equation modeling, we disaggregated shared from unique variation in the association between latent variable measures of maternal depression and ASD behaviors. Methods: Data were obtained from a study of preschoolers aged 2–4 newly diagnosed with ASD (n = 214). Information from a parent questionnaire, a semi-structured parent interview, and a semi-structured observational assessment was used to develop a latent variable measure of child ASD behaviors. Mothers reported on their own depression symptoms. We first modeled the covariance between maternal depression and child ASD behavior. Then, to quantify unique variation, we added covariance terms between maternal depression and the residual variation associated with the individual measures of child ASD behaviors. Results: The model demonstrated excellent fit to the underlying data. Maternal self-report of depression symptoms exhibited a significant association with the unique variance of the questionnaire report but not with the latent variable measure of child ASD behavior. A gradient pattern of association was demonstrated between maternal depression and the unique variance of the ASD measures: most strongly for the maternal questionnaire report, more weakly for the maternal semi-structured interview, and to a trivial extent for the observational interview. Conclusions: Parental depression may influence reporting of ASD behaviors in preschoolers. Shared method effects may also contribute to bias. This finding highlights the importance of obtaining multimethod reports of child ASD symptoms. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02451.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148
in Journal of Child Psychology and Psychiatry > 53-1 (January 2012) . - p.89-96[article] Influence of reporting effects on the association between maternal depression and child autism spectrum disorder behaviors [Texte imprimé et/ou numérique] / Teresa BENNETT, Auteur ; Michael H. BOYLE, Auteur ; Katholiki GEORGIADES, Auteur ; Stelios GEORGIADES, Auteur ; Ann THOMPSON, Auteur ; Eric DUKU, Auteur ; Susan E. BRYSON, Auteur ; Eric FOMBONNE, Auteur ; Tracy VAILLANCOURT, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Isabel M. SMITH, Auteur ; Pat MIRENDA, Auteur ; Wendy ROBERTS, Auteur ; Joanne VOLDEN, Auteur ; Charlotte WADDELL, Auteur ; THE PATHWAYS IN ASD STUDY TEAM, Auteur ; Peter SZATMARI, Auteur . - 2012 . - p.89-96.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 53-1 (January 2012) . - p.89-96
Mots-clés : Autistic disorder Asperger’s disorder methodology maternal depression structural equation modeling Index. décimale : PER Périodiques Résumé : Background: Maximizing measurement accuracy is an important aim in child development assessment and research. Parents are essential informants in the diagnostic process, and past research suggests that certain parental characteristics may influence how they report information about their children. This has not been studied in autism spectrum disorders (ASD) to date. We aimed, therefore, to investigate the possible effect that maternal depression might have on a mother’s reports of her child’s ASD behaviors. Using structural equation modeling, we disaggregated shared from unique variation in the association between latent variable measures of maternal depression and ASD behaviors. Methods: Data were obtained from a study of preschoolers aged 2–4 newly diagnosed with ASD (n = 214). Information from a parent questionnaire, a semi-structured parent interview, and a semi-structured observational assessment was used to develop a latent variable measure of child ASD behaviors. Mothers reported on their own depression symptoms. We first modeled the covariance between maternal depression and child ASD behavior. Then, to quantify unique variation, we added covariance terms between maternal depression and the residual variation associated with the individual measures of child ASD behaviors. Results: The model demonstrated excellent fit to the underlying data. Maternal self-report of depression symptoms exhibited a significant association with the unique variance of the questionnaire report but not with the latent variable measure of child ASD behavior. A gradient pattern of association was demonstrated between maternal depression and the unique variance of the ASD measures: most strongly for the maternal questionnaire report, more weakly for the maternal semi-structured interview, and to a trivial extent for the observational interview. Conclusions: Parental depression may influence reporting of ASD behaviors in preschoolers. Shared method effects may also contribute to bias. This finding highlights the importance of obtaining multimethod reports of child ASD symptoms. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02451.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148 Problem checklists and standardized diagnostic interviews: evidence of psychometric equivalence for classifying psychiatric disorder among children and youth in epidemiological studies / Michael H. BOYLE in Journal of Child Psychology and Psychiatry, 64-5 (May 2023)
[article]
Titre : Problem checklists and standardized diagnostic interviews: evidence of psychometric equivalence for classifying psychiatric disorder among children and youth in epidemiological studies Type de document : Texte imprimé et/ou numérique Auteurs : Michael H. BOYLE, Auteur ; Laura DUNCAN, Auteur ; Li WANG, Auteur ; Katholiki GEORGIADES, Auteur Article en page(s) : p.779-786 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background The standard approach for classifying child/youth psychiatric disorder as present or absent in epidemiological studies is lay-administered structured, standardized diagnostic interviews (interviews) based on categorical taxonomies such as the DSM and ICD. Converting problem checklist scale scores (checklists) to binary classifications provides a simple, inexpensive alternative. Methods Using assessments obtained from 737 parents, we determine if child/youth behavioral, attentional, and emotional disorder classifications based on checklists are equivalent psychometrically to interview classifications. We test this hypothesis by (1) comparing their test-retest reliabilities based on kappa (?), (2) estimating their observed agreement at times 1 and 2, and (3) in structural equation models, comparing their strength of association with clinical status and reported use of prescription medication to treat disorder. A confidence interval approach is used to determine if parameter differences lie within the smallest effect size of interest set at +0.125. Results The test-retest reliabilities (?) for interviews compared with checklists met criteria for statistical equivalence: behavioral, .67 and .70; attentional, .64 and .66; and emotional, .61 and .65. Observed agreement between the checklist and interviews on classifications of disorder at times 1 and 2 was, on average, ? = .61. On average, the ? coefficients estimating associations with clinical status were .59 (interviews) and .63 (checklists); and with prescription medication use, .69 (interviews) and .71 (checklists). Behavioral and attentional disorders met criteria for statistical equivalence. Emotional disorder did not, although the coefficients were stronger numerically for the checklist. Conclusions Classifications of child/youth psychiatric disorder from parent-reported checklists and interviews are equivalent psychometrically. The practical advantages of checklists over interviews for classifying disorder (lower administration cost and respondent burden) are enhanced by their ability to measure disorder dimensionally. Checklists provide an option to interviews in epidemiological studies of common child/youth psychiatric disorders. En ligne : https://doi.org/10.1111/jcpp.13735 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501
in Journal of Child Psychology and Psychiatry > 64-5 (May 2023) . - p.779-786[article] Problem checklists and standardized diagnostic interviews: evidence of psychometric equivalence for classifying psychiatric disorder among children and youth in epidemiological studies [Texte imprimé et/ou numérique] / Michael H. BOYLE, Auteur ; Laura DUNCAN, Auteur ; Li WANG, Auteur ; Katholiki GEORGIADES, Auteur . - p.779-786.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 64-5 (May 2023) . - p.779-786
Index. décimale : PER Périodiques Résumé : Background The standard approach for classifying child/youth psychiatric disorder as present or absent in epidemiological studies is lay-administered structured, standardized diagnostic interviews (interviews) based on categorical taxonomies such as the DSM and ICD. Converting problem checklist scale scores (checklists) to binary classifications provides a simple, inexpensive alternative. Methods Using assessments obtained from 737 parents, we determine if child/youth behavioral, attentional, and emotional disorder classifications based on checklists are equivalent psychometrically to interview classifications. We test this hypothesis by (1) comparing their test-retest reliabilities based on kappa (?), (2) estimating their observed agreement at times 1 and 2, and (3) in structural equation models, comparing their strength of association with clinical status and reported use of prescription medication to treat disorder. A confidence interval approach is used to determine if parameter differences lie within the smallest effect size of interest set at +0.125. Results The test-retest reliabilities (?) for interviews compared with checklists met criteria for statistical equivalence: behavioral, .67 and .70; attentional, .64 and .66; and emotional, .61 and .65. Observed agreement between the checklist and interviews on classifications of disorder at times 1 and 2 was, on average, ? = .61. On average, the ? coefficients estimating associations with clinical status were .59 (interviews) and .63 (checklists); and with prescription medication use, .69 (interviews) and .71 (checklists). Behavioral and attentional disorders met criteria for statistical equivalence. Emotional disorder did not, although the coefficients were stronger numerically for the checklist. Conclusions Classifications of child/youth psychiatric disorder from parent-reported checklists and interviews are equivalent psychometrically. The practical advantages of checklists over interviews for classifying disorder (lower administration cost and respondent burden) are enhanced by their ability to measure disorder dimensionally. Checklists provide an option to interviews in epidemiological studies of common child/youth psychiatric disorders. En ligne : https://doi.org/10.1111/jcpp.13735 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 Psychological Symptoms in Youth and Later Socioeconomic Functioning: Do Associations Vary by Informant ? / Melanie A. DIRKS in Journal of Clinical Child & Adolescent Psychology, 40-1 (January-February 2011)
PermalinkThe Brief Child and Family Phone Interview (BCFPI): 2. Usefulness in screening for child and adolescent psychopathology / Michael H. BOYLE in Journal of Child Psychology and Psychiatry, 50-4 (April 2009)
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