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Détail de l'auteur
Auteur William STARRETT |
Documents disponibles écrits par cet auteur (1)
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Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders / Joanna C. HAMLIN in Autism Research and Treatment, (January 2014)
[article]
Titre : Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Joanna C. HAMLIN, Auteur ; Margaret PAULY, Auteur ; Stepan MELNYK, Auteur ; Oleksandra PAVLIV, Auteur ; William STARRETT, Auteur ; Tina A. CROOK, Auteur ; S. Jill JAMES, Auteur Année de publication : 2014 Article en page(s) : 7 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abnormalities in folate-dependent one-carbon metabolism have been reported in many children with autism. Because inadequate choline and betaine can negatively affect folate metabolism and in turn downstream methylation and antioxidant capacity, we sought to determine whether dietary intake of choline and betaine in children with autism was adequate to meet nutritional needs based on national recommendations. Three-day food records were analyzed for 288 children with autism (ASDs) who participated in the national Autism Intervention Research Network for Physical Health (AIR-P) Study on Diet and Nutrition in children with autism. Plasma concentrations of choline and betaine were measured in a subgroup of 35 children with ASDs and 32 age-matched control children. The results indicated that 60–93% of children with ASDs were consuming less than the recommended Adequate Intake (AI) for choline. Strong positive correlations were found between dietary intake and plasma concentrations of choline and betaine in autistic children as well as lower plasma concentrations compared to the control group. We conclude that choline and betaine intake is inadequate in a significant subgroup of children with ASDs and is reflected in lower plasma levels. Inadequate intake of choline and betaine may contribute to the metabolic abnormalities observed in many children with autism and warrants attention in nutritional counseling. En ligne : http://dx.doi.org/10.1155/2013/578429 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=228
in Autism Research and Treatment > (January 2014) . - 7 p.[article] Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Joanna C. HAMLIN, Auteur ; Margaret PAULY, Auteur ; Stepan MELNYK, Auteur ; Oleksandra PAVLIV, Auteur ; William STARRETT, Auteur ; Tina A. CROOK, Auteur ; S. Jill JAMES, Auteur . - 2014 . - 7 p.
Langues : Anglais (eng)
in Autism Research and Treatment > (January 2014) . - 7 p.
Index. décimale : PER Périodiques Résumé : Abnormalities in folate-dependent one-carbon metabolism have been reported in many children with autism. Because inadequate choline and betaine can negatively affect folate metabolism and in turn downstream methylation and antioxidant capacity, we sought to determine whether dietary intake of choline and betaine in children with autism was adequate to meet nutritional needs based on national recommendations. Three-day food records were analyzed for 288 children with autism (ASDs) who participated in the national Autism Intervention Research Network for Physical Health (AIR-P) Study on Diet and Nutrition in children with autism. Plasma concentrations of choline and betaine were measured in a subgroup of 35 children with ASDs and 32 age-matched control children. The results indicated that 60–93% of children with ASDs were consuming less than the recommended Adequate Intake (AI) for choline. Strong positive correlations were found between dietary intake and plasma concentrations of choline and betaine in autistic children as well as lower plasma concentrations compared to the control group. We conclude that choline and betaine intake is inadequate in a significant subgroup of children with ASDs and is reflected in lower plasma levels. Inadequate intake of choline and betaine may contribute to the metabolic abnormalities observed in many children with autism and warrants attention in nutritional counseling. En ligne : http://dx.doi.org/10.1155/2013/578429 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=228