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Auteur Sarah O'NEILL |
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Latent profile analysis of neuropsychological measures to determine preschoolers' risk for ADHD / Khushmand RAJENDRAN in Journal of Child Psychology and Psychiatry, 56-9 (September 2015)
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Titre : Latent profile analysis of neuropsychological measures to determine preschoolers' risk for ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Khushmand RAJENDRAN, Auteur ; Sarah O'NEILL, Auteur ; David J. MARKS, Auteur ; Jeffrey M. HALPERIN, Auteur Article en page(s) : p.958-965 Langues : Anglais (eng) Mots-clés : Latent profile analysis preschool ADHD neuropsychology Index. décimale : PER Périodiques Résumé : Background Hyperactive/Inattentive preschool children show clear evidence of neuropsychological dysfunction. We examined whether patterns and severity of test scores could reliably identify subgroups of preschoolers with differential risk for ADHD during school-age. Method Typically developing (TD: n = 76) and Hyperactive/Inattentive (HI: n = 138) 3–4 year olds were assessed annually for 6 years (T1–T6). Latent profile analysis (LPA) was used to form subgroups among the HI group based on objective/neuropsychological measures (NEPSY, Actigraph and Continuous Performance Test). Logistic regression assessed the predictive validity of empirically formed subgroups at risk for ADHD diagnosis relative to the TD group and to each other from T2 to T6. Results Latent profile analysis yielded two subgroups of HI preschoolers: (a) selectively weak Attention/Executive functions, and (b) pervasive neuropsychological dysfunction across all measures. Both subgroups were more likely to have ADHD at all follow-up time-points relative to the TD group (OR range: 11.29–86.32), but there were no significant differences between the LPA-formed subgroups of HI children at any time-point. Conclusions Objective/neuropsychological measures distinguish HI preschoolers from their TD peers, but patterns and severity of neuropsychological dysfunction do not predict risk for ADHD during school-age. We hypothesize that trajectories in at-risk children are influenced by subsequent environmental and neurodevelopmental factors, raising the possibility that they are amenable to early intervention. En ligne : http://dx.doi.org/10.1111/jcpp.12434 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267
in Journal of Child Psychology and Psychiatry > 56-9 (September 2015) . - p.958-965[article] Latent profile analysis of neuropsychological measures to determine preschoolers' risk for ADHD [Texte imprimé et/ou numérique] / Khushmand RAJENDRAN, Auteur ; Sarah O'NEILL, Auteur ; David J. MARKS, Auteur ; Jeffrey M. HALPERIN, Auteur . - p.958-965.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-9 (September 2015) . - p.958-965
Mots-clés : Latent profile analysis preschool ADHD neuropsychology Index. décimale : PER Périodiques Résumé : Background Hyperactive/Inattentive preschool children show clear evidence of neuropsychological dysfunction. We examined whether patterns and severity of test scores could reliably identify subgroups of preschoolers with differential risk for ADHD during school-age. Method Typically developing (TD: n = 76) and Hyperactive/Inattentive (HI: n = 138) 3–4 year olds were assessed annually for 6 years (T1–T6). Latent profile analysis (LPA) was used to form subgroups among the HI group based on objective/neuropsychological measures (NEPSY, Actigraph and Continuous Performance Test). Logistic regression assessed the predictive validity of empirically formed subgroups at risk for ADHD diagnosis relative to the TD group and to each other from T2 to T6. Results Latent profile analysis yielded two subgroups of HI preschoolers: (a) selectively weak Attention/Executive functions, and (b) pervasive neuropsychological dysfunction across all measures. Both subgroups were more likely to have ADHD at all follow-up time-points relative to the TD group (OR range: 11.29–86.32), but there were no significant differences between the LPA-formed subgroups of HI children at any time-point. Conclusions Objective/neuropsychological measures distinguish HI preschoolers from their TD peers, but patterns and severity of neuropsychological dysfunction do not predict risk for ADHD during school-age. We hypothesize that trajectories in at-risk children are influenced by subsequent environmental and neurodevelopmental factors, raising the possibility that they are amenable to early intervention. En ligne : http://dx.doi.org/10.1111/jcpp.12434 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267