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Auteur Pär NYSTRÖM |
Documents disponibles écrits par cet auteur (4)
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Atypical Topographical Organization of Global Form and Motion Processing in 5-Month-Old Infants at Risk for Autism / Pär NYSTRÖM in Journal of Autism and Developmental Disorders, 51-1 (January 2021)
[article]
Titre : Atypical Topographical Organization of Global Form and Motion Processing in 5-Month-Old Infants at Risk for Autism Type de document : Texte imprimé et/ou numérique Auteurs : Pär NYSTRÖM, Auteur ; Emily JONES, Auteur ; Fahimeh DARKI, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur Article en page(s) : p.364-370 Langues : Anglais (eng) Mots-clés : Autism Developmental disorders Eeg Global coherence Infants Motion Index. décimale : PER Périodiques Résumé : Research indicates that individuals with autism spectrum disorder (ASD) are superior at local processing while the integration of local features to global percepts is reduced. Here, we compared infants at familiar risk for ASD to typically developing infants in terms of global coherence processing at 5 months of age, using steady state visually evoked potentials (SSVEP). We found a different topographical organization for global form and motion processing in infants at risk (n?=?50) than in controls (n?=?23). In contrast, activation patterns for local visual change were strikingly similar between groups. Although preliminary, the results represent the first neurophysiological evidence supporting the view that basic atypicalities in perception may play a role in the developmental pathways leading to ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04523-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438
in Journal of Autism and Developmental Disorders > 51-1 (January 2021) . - p.364-370[article] Atypical Topographical Organization of Global Form and Motion Processing in 5-Month-Old Infants at Risk for Autism [Texte imprimé et/ou numérique] / Pär NYSTRÖM, Auteur ; Emily JONES, Auteur ; Fahimeh DARKI, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur . - p.364-370.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-1 (January 2021) . - p.364-370
Mots-clés : Autism Developmental disorders Eeg Global coherence Infants Motion Index. décimale : PER Périodiques Résumé : Research indicates that individuals with autism spectrum disorder (ASD) are superior at local processing while the integration of local features to global percepts is reduced. Here, we compared infants at familiar risk for ASD to typically developing infants in terms of global coherence processing at 5 months of age, using steady state visually evoked potentials (SSVEP). We found a different topographical organization for global form and motion processing in infants at risk (n?=?50) than in controls (n?=?23). In contrast, activation patterns for local visual change were strikingly similar between groups. Although preliminary, the results represent the first neurophysiological evidence supporting the view that basic atypicalities in perception may play a role in the developmental pathways leading to ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04523-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438 Hypersensitive pupillary light reflex in infants at risk for autism / Pär NYSTRÖM in Molecular Autism, (March 2015)
[article]
Titre : Hypersensitive pupillary light reflex in infants at risk for autism Type de document : Texte imprimé et/ou numérique Auteurs : Pär NYSTRÖM, Auteur ; Gustaf GREDEBACK, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur Article en page(s) : p.1-6 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Post mortem brain tissue data and animal modeling work indicate cholinergic disruptions in autism. Moreover, the cholinergic system plays a key role in the early neurodevelopmental processes believed to be derailed early in life in individuals with the disorder. Yet, there is no data from human infants supporting a developmentally important role of this neurotransmitter system. Because the pupillary light reflex depends largely on cholinergic synaptic transmission, we assessed this reflex in a sample of infants at risk for autism as well as infants at low (average) risk. En ligne : http://dx.doi.org/10.1186/s13229-015-0011-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277
in Molecular Autism > (March 2015) . - p.1-6[article] Hypersensitive pupillary light reflex in infants at risk for autism [Texte imprimé et/ou numérique] / Pär NYSTRÖM, Auteur ; Gustaf GREDEBACK, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur . - p.1-6.
Langues : Anglais (eng)
in Molecular Autism > (March 2015) . - p.1-6
Index. décimale : PER Périodiques Résumé : Post mortem brain tissue data and animal modeling work indicate cholinergic disruptions in autism. Moreover, the cholinergic system plays a key role in the early neurodevelopmental processes believed to be derailed early in life in individuals with the disorder. Yet, there is no data from human infants supporting a developmentally important role of this neurotransmitter system. Because the pupillary light reflex depends largely on cholinergic synaptic transmission, we assessed this reflex in a sample of infants at risk for autism as well as infants at low (average) risk. En ligne : http://dx.doi.org/10.1186/s13229-015-0011-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 Larger pupil dilation to nonsocial sounds in infants with subsequent autism diagnosis / Maja RUDLING in Journal of Child Psychology and Psychiatry, 63-7 (July 2022)
[article]
Titre : Larger pupil dilation to nonsocial sounds in infants with subsequent autism diagnosis Type de document : Texte imprimé et/ou numérique Auteurs : Maja RUDLING, Auteur ; Pär NYSTRÖM, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur Article en page(s) : p.793-801 Langues : Anglais (eng) Mots-clés : Attention/physiology Auditory Perception/physiology Autism Spectrum Disorder/diagnosis Autistic Disorder Female Humans Infant Pupil/physiology Autism spectrum disorder auditory attention infancy pupil dilation Index. décimale : PER Périodiques Résumé : BACKGROUND: Studies of infants with an elevated likelihood of autism spectrum disorder can identify basic developmental processes that are associated with subsequently emerging clinical symptoms. Atypical responsiveness to sounds in infancy is such a potential early marker of autism. Here, we used pupillometry to quantify reactivity to social and nonsocial sounds in infants with a subsequent diagnosis. Previous research suggest that pupil dilation reflects attentional alerting, and link it to the locus coeruleus norepinephrine system. METHODS: We measured pupil dilation responses to child-directed speech and the sound of running water; sounds infants often hear in their everyday life. The final sample consisted of 99 ten-month-old infants (52 girls), of whom 68 had an elevated likelihood of autism and 31 were typically developing low-likelihood infants. At follow-up (36?months of age), 18 children in the elevated-likelihood group were diagnosed with autism. RESULTS: Compared to infants without diagnosis, the infants who were subsequently diagnosed with autism had larger pupil dilation when listening to nonsocial sounds, while reactivity to speech was strikingly similar between groups. In the total sample, more pupil dilation to the nonsocial sound was associated with higher levels of autistic symptoms. We also found that on a trial-by-trial basis, across all conditions and groups, more pupil dilation was associated with making fewer gaze shifts. CONCLUSIONS: This study did not find evidence of atypical pupillary reactivity to child-directed speech early in life in autism. Instead, the results suggest that certain nonsocial sounds elicit atypically strong alerting responses in infants with a subsequent autism diagnosis. These findings may have important theoretical and clinical implications. En ligne : http://dx.doi.org/10.1111/jcpp.13520 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477
in Journal of Child Psychology and Psychiatry > 63-7 (July 2022) . - p.793-801[article] Larger pupil dilation to nonsocial sounds in infants with subsequent autism diagnosis [Texte imprimé et/ou numérique] / Maja RUDLING, Auteur ; Pär NYSTRÖM, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur . - p.793-801.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-7 (July 2022) . - p.793-801
Mots-clés : Attention/physiology Auditory Perception/physiology Autism Spectrum Disorder/diagnosis Autistic Disorder Female Humans Infant Pupil/physiology Autism spectrum disorder auditory attention infancy pupil dilation Index. décimale : PER Périodiques Résumé : BACKGROUND: Studies of infants with an elevated likelihood of autism spectrum disorder can identify basic developmental processes that are associated with subsequently emerging clinical symptoms. Atypical responsiveness to sounds in infancy is such a potential early marker of autism. Here, we used pupillometry to quantify reactivity to social and nonsocial sounds in infants with a subsequent diagnosis. Previous research suggest that pupil dilation reflects attentional alerting, and link it to the locus coeruleus norepinephrine system. METHODS: We measured pupil dilation responses to child-directed speech and the sound of running water; sounds infants often hear in their everyday life. The final sample consisted of 99 ten-month-old infants (52 girls), of whom 68 had an elevated likelihood of autism and 31 were typically developing low-likelihood infants. At follow-up (36?months of age), 18 children in the elevated-likelihood group were diagnosed with autism. RESULTS: Compared to infants without diagnosis, the infants who were subsequently diagnosed with autism had larger pupil dilation when listening to nonsocial sounds, while reactivity to speech was strikingly similar between groups. In the total sample, more pupil dilation to the nonsocial sound was associated with higher levels of autistic symptoms. We also found that on a trial-by-trial basis, across all conditions and groups, more pupil dilation was associated with making fewer gaze shifts. CONCLUSIONS: This study did not find evidence of atypical pupillary reactivity to child-directed speech early in life in autism. Instead, the results suggest that certain nonsocial sounds elicit atypically strong alerting responses in infants with a subsequent autism diagnosis. These findings may have important theoretical and clinical implications. En ligne : http://dx.doi.org/10.1111/jcpp.13520 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 Motor atypicalities in infancy are associated with general developmental level at 2 years, but not autistic symptoms / Sheila ACHERMANN in Autism, 24-7 (October 2020)
[article]
Titre : Motor atypicalities in infancy are associated with general developmental level at 2 years, but not autistic symptoms Type de document : Texte imprimé et/ou numérique Auteurs : Sheila ACHERMANN, Auteur ; Pär NYSTRÖM, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur Article en page(s) : p.1650-1663 Langues : Anglais (eng) Mots-clés : *autism spectrum disorder *infancy *interceptive action skills *motion capture technology *motor development Index. décimale : PER Périodiques Résumé : Atypicalities in motor functioning are often observed in later born infant siblings of children with autism spectrum disorder. The goal of our study was to investigate motor functioning in infants with and without familial history of autism spectrum disorder. Specifically, we investigated how infants catch a ball that is rolling toward them following a non-straight path, a task that requires both efficient planning and execution. Their performance was measured using detailed three-dimensional motion capture technology. We found that several early motor functioning measures were different in infants with an older autistic sibling compared to controls. However, these early motor measures were not related to autistic symptoms at the age of 2 years. Instead, we found that some of the early motor measures were related to their subsequent non-social, general development. The findings of our study help us understand motor functioning early in life and how motor functioning is related to other aspects of development. En ligne : http://dx.doi.org/10.1177/1362361320918745 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=431
in Autism > 24-7 (October 2020) . - p.1650-1663[article] Motor atypicalities in infancy are associated with general developmental level at 2 years, but not autistic symptoms [Texte imprimé et/ou numérique] / Sheila ACHERMANN, Auteur ; Pär NYSTRÖM, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur . - p.1650-1663.
Langues : Anglais (eng)
in Autism > 24-7 (October 2020) . - p.1650-1663
Mots-clés : *autism spectrum disorder *infancy *interceptive action skills *motion capture technology *motor development Index. décimale : PER Périodiques Résumé : Atypicalities in motor functioning are often observed in later born infant siblings of children with autism spectrum disorder. The goal of our study was to investigate motor functioning in infants with and without familial history of autism spectrum disorder. Specifically, we investigated how infants catch a ball that is rolling toward them following a non-straight path, a task that requires both efficient planning and execution. Their performance was measured using detailed three-dimensional motion capture technology. We found that several early motor functioning measures were different in infants with an older autistic sibling compared to controls. However, these early motor measures were not related to autistic symptoms at the age of 2 years. Instead, we found that some of the early motor measures were related to their subsequent non-social, general development. The findings of our study help us understand motor functioning early in life and how motor functioning is related to other aspects of development. En ligne : http://dx.doi.org/10.1177/1362361320918745 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=431