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Détail de l'auteur
Auteur Karestan C. KOENEN |
Documents disponibles écrits par cet auteur (4)
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Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population / Elise B. ROBINSON in Journal of Autism and Developmental Disorders, 41-12 (December 2011)
[article]
Titre : Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population Type de document : Texte imprimé et/ou numérique Auteurs : Elise B. ROBINSON, Auteur ; Kerim M. MUNIR, Auteur ; Marie C. MCCORMICK, Auteur ; Karestan C. KOENEN, Auteur ; Susan L. SANTANGELO, Auteur Année de publication : 2011 Article en page(s) : p.1733-1737 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Autistic traits Parental age ALSPAC Index. décimale : PER Périodiques Résumé : This is the first investigation of the relationship between parental age and extreme social-communicative autistic traits in the general population. The parents of 5,246 children in the Avon Longitudinal Study of Parents and Children (ALSPAC) completed the Social and Communication Disorders Checklist (SCDC). The association between parental age and SCDC scores was assessed in the full sample and among high scoring individuals (e.g. top 5%, 1%). There was no association between parental age and social-communicative autistic traits in the general population. Neither maternal nor paternal age was associated with extreme scores. These findings suggest that advanced parental age does not confer increased risk for extreme social and communication impairment assessed quantitatively. En ligne : http://dx.doi.org/10.1007/s10803-011-1202-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148
in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1733-1737[article] Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population [Texte imprimé et/ou numérique] / Elise B. ROBINSON, Auteur ; Kerim M. MUNIR, Auteur ; Marie C. MCCORMICK, Auteur ; Karestan C. KOENEN, Auteur ; Susan L. SANTANGELO, Auteur . - 2011 . - p.1733-1737.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1733-1737
Mots-clés : Autism spectrum disorders Autistic traits Parental age ALSPAC Index. décimale : PER Périodiques Résumé : This is the first investigation of the relationship between parental age and extreme social-communicative autistic traits in the general population. The parents of 5,246 children in the Avon Longitudinal Study of Parents and Children (ALSPAC) completed the Social and Communication Disorders Checklist (SCDC). The association between parental age and SCDC scores was assessed in the full sample and among high scoring individuals (e.g. top 5%, 1%). There was no association between parental age and social-communicative autistic traits in the general population. Neither maternal nor paternal age was associated with extreme scores. These findings suggest that advanced parental age does not confer increased risk for extreme social and communication impairment assessed quantitatively. En ligne : http://dx.doi.org/10.1007/s10803-011-1202-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148 Research Review: DSM-V conduct disorder: research needs for an evidence base / Terrie E. MOFFITT in Journal of Child Psychology and Psychiatry, 49-1 (January 2008)
[article]
Titre : Research Review: DSM-V conduct disorder: research needs for an evidence base Type de document : Texte imprimé et/ou numérique Auteurs : Terrie E. MOFFITT, Auteur ; Julia KIM-COHEN, Auteur ; Essi VIDING, Auteur ; Sara R. JAFFEE, Auteur ; Louise ARSENEAULT, Auteur ; Karestan C. KOENEN, Auteur ; Candice L. ODGERS, Auteur ; Wendy S. SLUTSKE, Auteur Année de publication : 2007 Article en page(s) : p.3–33 Langues : Anglais (eng) Mots-clés : Conduct-disorder DSM-V Index. décimale : PER Périodiques Résumé : This article charts a strategic research course toward an empirical foundation for the diagnosis of conduct disorder in the forthcoming DSM-V. Since the DSM-IV appeared in 1994, an impressive amount of new information about conduct disorder has emerged. As a result of this new knowledge, reasonable rationales have been put forward for adding to the conduct disorder diagnostic protocol: a childhood-limited subtype, family psychiatric history, callous-unemotional traits, female-specific criteria, preschool-specific criteria, early substance use, and biomarkers from genetics, neuroimaging, and physiology research. This article reviews the evidence for these and other potential changes to the conduct disorder diagnosis. We report that although there is a great deal of exciting research into each of the topics, very little of it provides the precise sort of evidence base required to justify any alteration to the DSM-V. We outline specific research questions and study designs needed to build the lacking evidence base for or against proposed changes to DSM-V conduct disorder. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01823.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310
in Journal of Child Psychology and Psychiatry > 49-1 (January 2008) . - p.3–33[article] Research Review: DSM-V conduct disorder: research needs for an evidence base [Texte imprimé et/ou numérique] / Terrie E. MOFFITT, Auteur ; Julia KIM-COHEN, Auteur ; Essi VIDING, Auteur ; Sara R. JAFFEE, Auteur ; Louise ARSENEAULT, Auteur ; Karestan C. KOENEN, Auteur ; Candice L. ODGERS, Auteur ; Wendy S. SLUTSKE, Auteur . - 2007 . - p.3–33.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 49-1 (January 2008) . - p.3–33
Mots-clés : Conduct-disorder DSM-V Index. décimale : PER Périodiques Résumé : This article charts a strategic research course toward an empirical foundation for the diagnosis of conduct disorder in the forthcoming DSM-V. Since the DSM-IV appeared in 1994, an impressive amount of new information about conduct disorder has emerged. As a result of this new knowledge, reasonable rationales have been put forward for adding to the conduct disorder diagnostic protocol: a childhood-limited subtype, family psychiatric history, callous-unemotional traits, female-specific criteria, preschool-specific criteria, early substance use, and biomarkers from genetics, neuroimaging, and physiology research. This article reviews the evidence for these and other potential changes to the conduct disorder diagnosis. We report that although there is a great deal of exciting research into each of the topics, very little of it provides the precise sort of evidence base required to justify any alteration to the DSM-V. We outline specific research questions and study designs needed to build the lacking evidence base for or against proposed changes to DSM-V conduct disorder. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01823.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310 Research Review: Gene–environment interaction research in youth depression – a systematic review with recommendations for future research / Erin C. DUNN in Journal of Child Psychology and Psychiatry, 52-12 (December 2011)
[article]
Titre : Research Review: Gene–environment interaction research in youth depression – a systematic review with recommendations for future research Type de document : Texte imprimé et/ou numérique Auteurs : Erin C. DUNN, Auteur ; Monica UDDIN, Auteur ; S.V. SUBRAMANIAN, Auteur ; Jordan W. SMOLLER, Auteur ; Sandro GALEA, Auteur ; Karestan C. KOENEN, Auteur Année de publication : 2011 Article en page(s) : p.1223-1338 Langues : Anglais (eng) Mots-clés : Depression children adolescents youth gene environment interaction Index. décimale : PER Périodiques Résumé : Background: Depression is a major public health problem among youth, currently estimated to affect as many as 9% of US children and adolescents. The recognition that both genes (nature) and environments (nurture) are important for understanding the etiology of depression has led to a rapid growth in research exploring gene–environment interactions (GxE). However, there has been no systematic review of GxE in youth depression to date.
Methods: The goal of this article was to systematically review evidence on the contribution of GxE to the risk of child and adolescent depression. Through a search of PubMed and PsycINFO databases to 1 April 2010, we identified 20 candidate gene–environment interaction studies focused on depression in youth (up to age 26) and compared each study in terms of the following characteristics: research design and sample studied; measure of depression and environment used; genes explored; and GxE findings in relation to these factors.
Results: In total, 80% of studies (n = 16) found at least one significant GxE association. However, there was wide variation in methods and analyses adopted across studies, especially with respect to environmental measures used and tests conducted to estimate GxE. This heterogeneity made it difficult to compare findings and evaluate the strength of the evidence for GxE.
Conclusions: The existing body of GxE research on depression in youth contains studies that are conceptually and methodologically quite different, which contributes to mixed findings and makes it difficult to assess the current state of the evidence. To decrease this heterogeneity, we offer 20 recommendations that are focused on: (a) reporting GxE research; (b) testing and reporting GxE effects; (c) conceptualizing, measuring and analyzing depression; (d) conceptualizing, measuring and analyzing environment; (e) increasing power to test for GxE; and (f) improving the quality of genetic data used. Although targeted to GxE research on depression, these recommendations can be adopted by GxE researchers focusing on other mental health outcomes.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02466.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146
in Journal of Child Psychology and Psychiatry > 52-12 (December 2011) . - p.1223-1338[article] Research Review: Gene–environment interaction research in youth depression – a systematic review with recommendations for future research [Texte imprimé et/ou numérique] / Erin C. DUNN, Auteur ; Monica UDDIN, Auteur ; S.V. SUBRAMANIAN, Auteur ; Jordan W. SMOLLER, Auteur ; Sandro GALEA, Auteur ; Karestan C. KOENEN, Auteur . - 2011 . - p.1223-1338.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 52-12 (December 2011) . - p.1223-1338
Mots-clés : Depression children adolescents youth gene environment interaction Index. décimale : PER Périodiques Résumé : Background: Depression is a major public health problem among youth, currently estimated to affect as many as 9% of US children and adolescents. The recognition that both genes (nature) and environments (nurture) are important for understanding the etiology of depression has led to a rapid growth in research exploring gene–environment interactions (GxE). However, there has been no systematic review of GxE in youth depression to date.
Methods: The goal of this article was to systematically review evidence on the contribution of GxE to the risk of child and adolescent depression. Through a search of PubMed and PsycINFO databases to 1 April 2010, we identified 20 candidate gene–environment interaction studies focused on depression in youth (up to age 26) and compared each study in terms of the following characteristics: research design and sample studied; measure of depression and environment used; genes explored; and GxE findings in relation to these factors.
Results: In total, 80% of studies (n = 16) found at least one significant GxE association. However, there was wide variation in methods and analyses adopted across studies, especially with respect to environmental measures used and tests conducted to estimate GxE. This heterogeneity made it difficult to compare findings and evaluate the strength of the evidence for GxE.
Conclusions: The existing body of GxE research on depression in youth contains studies that are conceptually and methodologically quite different, which contributes to mixed findings and makes it difficult to assess the current state of the evidence. To decrease this heterogeneity, we offer 20 recommendations that are focused on: (a) reporting GxE research; (b) testing and reporting GxE effects; (c) conceptualizing, measuring and analyzing depression; (d) conceptualizing, measuring and analyzing environment; (e) increasing power to test for GxE; and (f) improving the quality of genetic data used. Although targeted to GxE research on depression, these recommendations can be adopted by GxE researchers focusing on other mental health outcomes.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02466.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146 Women's posttraumatic stress symptoms and autism spectrum disorder in their children / Andrea L. ROBERTS in Research in Autism Spectrum Disorders, 8-6 (June 2014)
[article]
Titre : Women's posttraumatic stress symptoms and autism spectrum disorder in their children Type de document : Texte imprimé et/ou numérique Auteurs : Andrea L. ROBERTS, Auteur ; Karestan C. KOENEN, Auteur ; Kristen LYALL, Auteur ; Alberto ASCHERIO, Auteur ; Marc G. WEISSKOPF, Auteur Article en page(s) : p.608-616 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Posttraumatic stress disorder Gestational effects Index. décimale : PER Périodiques Résumé : Maternal posttraumatic stress disorder (PTSD) may be associated with autism spectrum disorder (ASD) in offspring through multiple pathways: maternal stress may affect the fetus; ASD in children may increase risk of PTSD in mothers; and the two disorders may share genetic risk. Understanding whether maternal PTSD is associated with child's ASD is important for clinicians treating children with ASD, as PTSD in parents is associated with poorer family functioning. We examined the association of maternal PTSD with offspring ASD in a large US cohort (N ASD cases = 413, N controls = 42,868). Mother's PTSD symptoms were strongly associated with child's ASD (RR 4–5 PTSD symptoms = 1.98, 95% CI = 1.39, 2.81; RR 6–7 symptoms = 2.89, 95% CI = 2.00, 4.18). Clinicians treating persons with ASD should be aware of elevated risk of PTSD in the mother. Genetic studies should investigate PTSD risk alleles in relation to ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.02.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232
in Research in Autism Spectrum Disorders > 8-6 (June 2014) . - p.608-616[article] Women's posttraumatic stress symptoms and autism spectrum disorder in their children [Texte imprimé et/ou numérique] / Andrea L. ROBERTS, Auteur ; Karestan C. KOENEN, Auteur ; Kristen LYALL, Auteur ; Alberto ASCHERIO, Auteur ; Marc G. WEISSKOPF, Auteur . - p.608-616.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 8-6 (June 2014) . - p.608-616
Mots-clés : Autism spectrum disorder Posttraumatic stress disorder Gestational effects Index. décimale : PER Périodiques Résumé : Maternal posttraumatic stress disorder (PTSD) may be associated with autism spectrum disorder (ASD) in offspring through multiple pathways: maternal stress may affect the fetus; ASD in children may increase risk of PTSD in mothers; and the two disorders may share genetic risk. Understanding whether maternal PTSD is associated with child's ASD is important for clinicians treating children with ASD, as PTSD in parents is associated with poorer family functioning. We examined the association of maternal PTSD with offspring ASD in a large US cohort (N ASD cases = 413, N controls = 42,868). Mother's PTSD symptoms were strongly associated with child's ASD (RR 4–5 PTSD symptoms = 1.98, 95% CI = 1.39, 2.81; RR 6–7 symptoms = 2.89, 95% CI = 2.00, 4.18). Clinicians treating persons with ASD should be aware of elevated risk of PTSD in the mother. Genetic studies should investigate PTSD risk alleles in relation to ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.02.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232