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Détail de l'auteur
Auteur David G. INGRAM |
Documents disponibles écrits par cet auteur (1)
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Defining Autism Subgroups: A Taxometric Solution / David G. INGRAM in Journal of Autism and Developmental Disorders, 38-5 (May 2008)
[article]
Titre : Defining Autism Subgroups: A Taxometric Solution Type de document : Texte imprimé et/ou numérique Auteurs : David G. INGRAM, Auteur ; T. Nicole TAKAHASHI, Auteur ; Judith H. MILES, Auteur Année de publication : 2008 Article en page(s) : p.950-960 Langues : Anglais (eng) Mots-clés : Autism subgroups - Taxometrics Index. décimale : PER Périodiques Résumé : The purpose of the present study was to determine which behavioral and physical phenotypes would be most likely to divide the ASD population into discrete subgroups. The taxometric methods of Maximum Covariance (MAXCOV) and Minus Mean Below A Cut (MAMBAC) were employed to test for categorical versus continuous variation of each phenotype across the ASD population. Data was retrieved from the Autism Genetic Resource Exchange and the University of Missouri Autism Database. The results of our analyses support subgrouping subjects based on variation in social interaction/communication, intelligence, and essential/complex phenotype; in contrast, subjects varied continuously in insistence on sameness, repetitive sensory motor actions, language acquisition, and, tentatively, adaptive functioning. Stratifying ASD samples based on taxometric results should increase power in gene-finding studies and aid in treatment efficacy research. En ligne : http://dx.doi.org/10.1007/s10803-007-0469-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=417
in Journal of Autism and Developmental Disorders > 38-5 (May 2008) . - p.950-960[article] Defining Autism Subgroups: A Taxometric Solution [Texte imprimé et/ou numérique] / David G. INGRAM, Auteur ; T. Nicole TAKAHASHI, Auteur ; Judith H. MILES, Auteur . - 2008 . - p.950-960.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 38-5 (May 2008) . - p.950-960
Mots-clés : Autism subgroups - Taxometrics Index. décimale : PER Périodiques Résumé : The purpose of the present study was to determine which behavioral and physical phenotypes would be most likely to divide the ASD population into discrete subgroups. The taxometric methods of Maximum Covariance (MAXCOV) and Minus Mean Below A Cut (MAMBAC) were employed to test for categorical versus continuous variation of each phenotype across the ASD population. Data was retrieved from the Autism Genetic Resource Exchange and the University of Missouri Autism Database. The results of our analyses support subgrouping subjects based on variation in social interaction/communication, intelligence, and essential/complex phenotype; in contrast, subjects varied continuously in insistence on sameness, repetitive sensory motor actions, language acquisition, and, tentatively, adaptive functioning. Stratifying ASD samples based on taxometric results should increase power in gene-finding studies and aid in treatment efficacy research. En ligne : http://dx.doi.org/10.1007/s10803-007-0469-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=417