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Auteur Johnny DOWNS |
Documents disponibles écrits par cet auteur (2)
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Association between depression diagnosis and educational attainment trajectories: an historical cohort study using linked data / Alice WICKERSHAM in Journal of Child Psychology and Psychiatry, 64-11 (November 2023)
[article]
Titre : Association between depression diagnosis and educational attainment trajectories: an historical cohort study using linked data Type de document : Texte imprimé et/ou numérique Auteurs : Alice WICKERSHAM, Auteur ; Ben CARTER, Auteur ; Amelia JEWELL, Auteur ; Tamsin FORD, Auteur ; Robert STEWART, Auteur ; Johnny DOWNS, Auteur Article en page(s) : p.1617-1627 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Depression symptoms are thought to be associated with lower educational attainment, but patterns of change in attainment among those who receive a clinical diagnosis of depression at any point during childhood and adolescence remain unclear. Methods We conducted a secondary analysis of an existing data linkage between a national educational dataset (National Pupil Database) and pseudonymised electronic health records (Clinical Record Interactive Search) from a large mental healthcare provider in London, United Kingdom (2007 to 2013). A cohort of 222,027 pupils were included. We used Growth Mixture Modelling (GMM) and stakeholder input to estimate trajectories of standardised educational attainment over School Years 2, 6 and 11. Multinomial logistic regression analyses were then used to investigate the association between resulting educational attainment trajectory membership (outcome) and depression diagnosis any time before age 18 (exposure). Results A five-trajectory GMM solution for attainment was derived: (1) average/high-stable, (2) average-modest declining, (3) average-steep declining, (4) low-improving and (5) low-stable. After adjusting for clinical and sociodemographic covariates, having a depression diagnosis before age 18 was associated with occupying the average-modest declining trajectory (RRR = 2.80, 95% CI 2.36-3.32, p<.001) or the average-steep declining trajectory (RRR = 3.54, 95% CI 3.10-4.04, p<.001), as compared to the average/high-stable trajectory. Conclusions Receiving a diagnosis of depression before age 18 was associated with a relative decline in attainment throughout school. While these findings cannot support a causal direction, they nonetheless suggest a need for timely mental health and educational support among pupils struggling with depression. En ligne : https://doi.org/10.1111/jcpp.13759 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512
in Journal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1617-1627[article] Association between depression diagnosis and educational attainment trajectories: an historical cohort study using linked data [Texte imprimé et/ou numérique] / Alice WICKERSHAM, Auteur ; Ben CARTER, Auteur ; Amelia JEWELL, Auteur ; Tamsin FORD, Auteur ; Robert STEWART, Auteur ; Johnny DOWNS, Auteur . - p.1617-1627.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1617-1627
Index. décimale : PER Périodiques Résumé : Background Depression symptoms are thought to be associated with lower educational attainment, but patterns of change in attainment among those who receive a clinical diagnosis of depression at any point during childhood and adolescence remain unclear. Methods We conducted a secondary analysis of an existing data linkage between a national educational dataset (National Pupil Database) and pseudonymised electronic health records (Clinical Record Interactive Search) from a large mental healthcare provider in London, United Kingdom (2007 to 2013). A cohort of 222,027 pupils were included. We used Growth Mixture Modelling (GMM) and stakeholder input to estimate trajectories of standardised educational attainment over School Years 2, 6 and 11. Multinomial logistic regression analyses were then used to investigate the association between resulting educational attainment trajectory membership (outcome) and depression diagnosis any time before age 18 (exposure). Results A five-trajectory GMM solution for attainment was derived: (1) average/high-stable, (2) average-modest declining, (3) average-steep declining, (4) low-improving and (5) low-stable. After adjusting for clinical and sociodemographic covariates, having a depression diagnosis before age 18 was associated with occupying the average-modest declining trajectory (RRR = 2.80, 95% CI 2.36-3.32, p<.001) or the average-steep declining trajectory (RRR = 3.54, 95% CI 3.10-4.04, p<.001), as compared to the average/high-stable trajectory. Conclusions Receiving a diagnosis of depression before age 18 was associated with a relative decline in attainment throughout school. While these findings cannot support a causal direction, they nonetheless suggest a need for timely mental health and educational support among pupils struggling with depression. En ligne : https://doi.org/10.1111/jcpp.13759 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512 Investigating Bullying as a Predictor of Suicidality in a Clinical Sample of Adolescents with Autism Spectrum Disorder / Rachel HOLDEN in Autism Research, 13-6 (June 2020)
[article]
Titre : Investigating Bullying as a Predictor of Suicidality in a Clinical Sample of Adolescents with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Rachel HOLDEN, Auteur ; Joanne MUELLER, Auteur ; John MCGOWAN, Auteur ; Jyoti SANYAL, Auteur ; Maxim KIKOLER, Auteur ; Emily SIMONOFF, Auteur ; Sumithra VELUPILLAI, Auteur ; Johnny DOWNS, Auteur Article en page(s) : p.988-997 Langues : Anglais (eng) Mots-clés : adolescents clinical psychiatry comorbid conditions data-driven techniques epidemiology longitudinal data analysis Index. décimale : PER Périodiques Résumé : For typically developing adolescents, being bullied is associated with increased risk of suicidality. Although adolescents with autism spectrum disorder (ASD) are at increased risk of both bullying and suicidality, there is very little research that examines the extent to which an experience of being bullied may increase suicidality within this specific population. To address this, we conducted a retrospective cohort study to investigate the longitudinal association between experiencing bullying and suicidality in a clinical population of 680 adolescents with ASD. Electronic health records of adolescents (13-17?years), using mental health services in South London, with a diagnosis of ASD were analyzed. Natural language processing was employed to identify mentions of bullying and suicidality in the free text fields of adolescents' clinical records. Cox regression analysis was employed to investigate the longitudinal relationship between bullying and suicidality outcomes. Reported experience of bullying in the first month of clinical contact was associated with an increased risk suicidality over the follow-up period (hazard ratio = 1.82; 95% confidence interval = 1.28-2.59). In addition, female gender, psychosis, affective disorder diagnoses, and higher intellectual ability were all associated with suicidality at follow-up. This study is the first to demonstrate the strength of longitudinal associations between bullying and suicidality in a clinical population of adolescents with ASD, using automated approaches to detect key life events within clinical records. Our findings provide support for identifying and dealing with bullying in schools, and for antibullying strategy's incorporation into wider suicide prevention programs for young people with ASD. Autism Res 2020, 13: 988-997. © 2020 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: We investigated the relationship between bullying and suicidality in young people with autism spectrum disorder (ASD). We examined the clinical records of adolescents (aged 13-18?years old) with ASD in South London who were receiving treatment from Child and Adolescent Mental Health Services. We found that if they reported being bullied in the first month after they were first seen by mental health services, they were nearly twice as likely to go on to develop suicidal thoughts or behaviors. En ligne : http://dx.doi.org/10.1002/aur.2292 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427
in Autism Research > 13-6 (June 2020) . - p.988-997[article] Investigating Bullying as a Predictor of Suicidality in a Clinical Sample of Adolescents with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Rachel HOLDEN, Auteur ; Joanne MUELLER, Auteur ; John MCGOWAN, Auteur ; Jyoti SANYAL, Auteur ; Maxim KIKOLER, Auteur ; Emily SIMONOFF, Auteur ; Sumithra VELUPILLAI, Auteur ; Johnny DOWNS, Auteur . - p.988-997.
Langues : Anglais (eng)
in Autism Research > 13-6 (June 2020) . - p.988-997
Mots-clés : adolescents clinical psychiatry comorbid conditions data-driven techniques epidemiology longitudinal data analysis Index. décimale : PER Périodiques Résumé : For typically developing adolescents, being bullied is associated with increased risk of suicidality. Although adolescents with autism spectrum disorder (ASD) are at increased risk of both bullying and suicidality, there is very little research that examines the extent to which an experience of being bullied may increase suicidality within this specific population. To address this, we conducted a retrospective cohort study to investigate the longitudinal association between experiencing bullying and suicidality in a clinical population of 680 adolescents with ASD. Electronic health records of adolescents (13-17?years), using mental health services in South London, with a diagnosis of ASD were analyzed. Natural language processing was employed to identify mentions of bullying and suicidality in the free text fields of adolescents' clinical records. Cox regression analysis was employed to investigate the longitudinal relationship between bullying and suicidality outcomes. Reported experience of bullying in the first month of clinical contact was associated with an increased risk suicidality over the follow-up period (hazard ratio = 1.82; 95% confidence interval = 1.28-2.59). In addition, female gender, psychosis, affective disorder diagnoses, and higher intellectual ability were all associated with suicidality at follow-up. This study is the first to demonstrate the strength of longitudinal associations between bullying and suicidality in a clinical population of adolescents with ASD, using automated approaches to detect key life events within clinical records. Our findings provide support for identifying and dealing with bullying in schools, and for antibullying strategy's incorporation into wider suicide prevention programs for young people with ASD. Autism Res 2020, 13: 988-997. © 2020 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: We investigated the relationship between bullying and suicidality in young people with autism spectrum disorder (ASD). We examined the clinical records of adolescents (aged 13-18?years old) with ASD in South London who were receiving treatment from Child and Adolescent Mental Health Services. We found that if they reported being bullied in the first month after they were first seen by mental health services, they were nearly twice as likely to go on to develop suicidal thoughts or behaviors. En ligne : http://dx.doi.org/10.1002/aur.2292 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427