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The co-occurrence of autism spectrum disorder and attention-deficit/hyperactivity disorder symptoms in parents of children with ASD or ASD with ADHD / Daphne J. VAN STEIJN in Journal of Child Psychology and Psychiatry, 53-9 (September 2012)
[article]
Titre : The co-occurrence of autism spectrum disorder and attention-deficit/hyperactivity disorder symptoms in parents of children with ASD or ASD with ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Daphne J. VAN STEIJN, Auteur ; Jennifer S. RICHARDS, Auteur ; Anoek M. OERLEMANS, Auteur ; Saskia W. DE RUITER, Auteur ; Marcel A. G. VAN AKEN, Auteur ; Barbara FRANKE, Auteur ; Jan K. BUITELAAR, Auteur ; Nanda N. ROMMELSE, Auteur Année de publication : 2012 Article en page(s) : p.954-63 Langues : Anglais (eng) Mots-clés : Assortative mating parent-of-origin effect autism spectrum disorder attention-deficit/hyperactivity disorder Index. décimale : PER Périodiques Résumé : Background: Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) share about 50–72% of their genetic factors, which is the most likely explanation for their frequent co-occurrence within the same patient or family. An additional or alternative explanation for the co-occurrence may be (cross-)assortative mating, e.g., the tendency to choose a partner that is similar or dissimilar to oneself. Another issue is that of parent-of-origin effect which refers to the possibility of parents differing in the relative quantity of risk factors they transmit to the offspring. The current study sets out to examine (cross-)assortative mating and (cross-)parent-of-origin effects of ASD and ADHD in parents of children with either ASD or ASD with ADHD diagnosis. Methods: In total, 121 families were recruited in an ongoing autism-ADHD family genetics project. Participating families consisted of parents and at least one child aged between 2 and 20 years, with either autistic disorder, Asperger disorder or PDD-NOS, and one or more biological siblings. All children and parents were carefully screened for the presence of ASD and ADHD. Results: No correlations were found between maternal and paternal ASD and ADHD symptoms. Parental ASD and ADHD symptoms were predictive for similar symptoms in the offspring, but with maternal hyperactive-impulsive symptoms, but not paternal symptoms, predicting similar symptoms in daughters. ASD pathology in the parents was not predictive for ADHD pathology in the offspring, but mother’s ADHD pathology was predictive for offspring ASD pathology even when corrected for maternal ASD pathology. Conclusions: Cross-assortative mating for ASD and ADHD does not form an explanation for the frequent co-occurrence of these disorders within families. Given that parental ADHD is predictive of offspring’ ASD but not vice versa, risk factors underlying ASD may overlap to a larger degree with risk factors underlying ADHD than vice versa. However, future research is needed to clarify this issue. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02556.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=179
in Journal of Child Psychology and Psychiatry > 53-9 (September 2012) . - p.954-63[article] The co-occurrence of autism spectrum disorder and attention-deficit/hyperactivity disorder symptoms in parents of children with ASD or ASD with ADHD [Texte imprimé et/ou numérique] / Daphne J. VAN STEIJN, Auteur ; Jennifer S. RICHARDS, Auteur ; Anoek M. OERLEMANS, Auteur ; Saskia W. DE RUITER, Auteur ; Marcel A. G. VAN AKEN, Auteur ; Barbara FRANKE, Auteur ; Jan K. BUITELAAR, Auteur ; Nanda N. ROMMELSE, Auteur . - 2012 . - p.954-63.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 53-9 (September 2012) . - p.954-63
Mots-clés : Assortative mating parent-of-origin effect autism spectrum disorder attention-deficit/hyperactivity disorder Index. décimale : PER Périodiques Résumé : Background: Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) share about 50–72% of their genetic factors, which is the most likely explanation for their frequent co-occurrence within the same patient or family. An additional or alternative explanation for the co-occurrence may be (cross-)assortative mating, e.g., the tendency to choose a partner that is similar or dissimilar to oneself. Another issue is that of parent-of-origin effect which refers to the possibility of parents differing in the relative quantity of risk factors they transmit to the offspring. The current study sets out to examine (cross-)assortative mating and (cross-)parent-of-origin effects of ASD and ADHD in parents of children with either ASD or ASD with ADHD diagnosis. Methods: In total, 121 families were recruited in an ongoing autism-ADHD family genetics project. Participating families consisted of parents and at least one child aged between 2 and 20 years, with either autistic disorder, Asperger disorder or PDD-NOS, and one or more biological siblings. All children and parents were carefully screened for the presence of ASD and ADHD. Results: No correlations were found between maternal and paternal ASD and ADHD symptoms. Parental ASD and ADHD symptoms were predictive for similar symptoms in the offspring, but with maternal hyperactive-impulsive symptoms, but not paternal symptoms, predicting similar symptoms in daughters. ASD pathology in the parents was not predictive for ADHD pathology in the offspring, but mother’s ADHD pathology was predictive for offspring ASD pathology even when corrected for maternal ASD pathology. Conclusions: Cross-assortative mating for ASD and ADHD does not form an explanation for the frequent co-occurrence of these disorders within families. Given that parental ADHD is predictive of offspring’ ASD but not vice versa, risk factors underlying ASD may overlap to a larger degree with risk factors underlying ADHD than vice versa. However, future research is needed to clarify this issue. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02556.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=179 The cognitive/behavioural phenotype in autism / Daria RIVA
Titre : The cognitive/behavioural phenotype in autism Type de document : Texte imprimé et/ou numérique Auteurs : Daria RIVA, Auteur ; Francesca NICHELLI, Auteur ; Chiara VAGO, Auteur ; Sara BULGHERONI, Auteur Année de publication : 2005 Importance : p.107-116 Langues : Anglais (eng) Index. décimale : TRO-F TRO-F - Autres Troubles Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=161 The cognitive/behavioural phenotype in autism [Texte imprimé et/ou numérique] / Daria RIVA, Auteur ; Francesca NICHELLI, Auteur ; Chiara VAGO, Auteur ; Sara BULGHERONI, Auteur . - 2005 . - p.107-116.
Langues : Anglais (eng)
Index. décimale : TRO-F TRO-F - Autres Troubles Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=161 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire The complementary role of high sensitivity C-reactive protein in the diagnosis and severity assessment of autism / Mohammad Reza KHAKZAD in Research in Autism Spectrum Disorders, 6-3 (July-September 2012)
[article]
Titre : The complementary role of high sensitivity C-reactive protein in the diagnosis and severity assessment of autism Type de document : Texte imprimé et/ou numérique Auteurs : Mohammad Reza KHAKZAD, Auteur ; Maryam JAVANBAKHT, Auteur ; Mohammad Reza SHAYEGAN, Auteur ; Sina KIANOUSH, Auteur ; Fatemeh OMID, Auteur ; Maryam HOJATI, Auteur ; Mojtaba MESHKAT, Auteur Année de publication : 2012 Article en page(s) : p.1032-1037 Langues : Anglais (eng) Mots-clés : Autistic disorder C-reactive protein Inflammation Severity Index. décimale : PER Périodiques Résumé : C-reactive protein (CRP) is a beneficial diagnostic test for the evaluation of inflammatory response. Extremely low levels of CRP can be detected using high-sensitivity CRP (hs-CRP) test. A considerable body of evidence has demonstrated that inflammatory response has an important role in the pathophysiology of autism. In this study, we evaluated and compared hs-CRP levels between autistic and intellectually normal individuals. Clinical data of 39 autistic and 30 age-matched intellectually normal individuals (control group) were recorded. Patients were divided into two groups (mild-to-moderate and severe) according to childhood autism rating scale. Then serum hs-CRP concentrations were measured and compared between two groups. Also, the correlation between hs-CRP concentration and the severity of autism was determined. The mean concentration of hs-CRP in children with autism (540.1 ± 1125.5 ng/ml) was significantly (P < 0.0001) higher than control group (1.3 ± 1.0 ng/ml). In severe autism, the mean level of hs-CRP (985.1 ± 1432.1 ng/ml) was significantly (P = 0.008) higher than the mean level of hs-CRP in patients with mild-to-moderate autism (147.1 ± 60.4 ng/ml). There was a positive correlation between hs-CRP concentration and autism severity (r = 0.34; P = 0.039). These findings affirm the role of inflammation in autism. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.10.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154
in Research in Autism Spectrum Disorders > 6-3 (July-September 2012) . - p.1032-1037[article] The complementary role of high sensitivity C-reactive protein in the diagnosis and severity assessment of autism [Texte imprimé et/ou numérique] / Mohammad Reza KHAKZAD, Auteur ; Maryam JAVANBAKHT, Auteur ; Mohammad Reza SHAYEGAN, Auteur ; Sina KIANOUSH, Auteur ; Fatemeh OMID, Auteur ; Maryam HOJATI, Auteur ; Mojtaba MESHKAT, Auteur . - 2012 . - p.1032-1037.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 6-3 (July-September 2012) . - p.1032-1037
Mots-clés : Autistic disorder C-reactive protein Inflammation Severity Index. décimale : PER Périodiques Résumé : C-reactive protein (CRP) is a beneficial diagnostic test for the evaluation of inflammatory response. Extremely low levels of CRP can be detected using high-sensitivity CRP (hs-CRP) test. A considerable body of evidence has demonstrated that inflammatory response has an important role in the pathophysiology of autism. In this study, we evaluated and compared hs-CRP levels between autistic and intellectually normal individuals. Clinical data of 39 autistic and 30 age-matched intellectually normal individuals (control group) were recorded. Patients were divided into two groups (mild-to-moderate and severe) according to childhood autism rating scale. Then serum hs-CRP concentrations were measured and compared between two groups. Also, the correlation between hs-CRP concentration and the severity of autism was determined. The mean concentration of hs-CRP in children with autism (540.1 ± 1125.5 ng/ml) was significantly (P < 0.0001) higher than control group (1.3 ± 1.0 ng/ml). In severe autism, the mean level of hs-CRP (985.1 ± 1432.1 ng/ml) was significantly (P = 0.008) higher than the mean level of hs-CRP in patients with mild-to-moderate autism (147.1 ± 60.4 ng/ml). There was a positive correlation between hs-CRP concentration and autism severity (r = 0.34; P = 0.039). These findings affirm the role of inflammation in autism. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.10.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154 The Cranial Circumference in Autism / Michele ZAPPELLA
Titre : The Cranial Circumference in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Michele ZAPPELLA, Auteur Année de publication : 2005 Importance : p.91-100 Langues : Anglais (eng) Mots-clés : Périmetre cranien Syndrome Sotos Neurofibromatose de type 1 Hypomélanose de Ito Syndrome des hamartomes par mutation du gène PTEN Index. décimale : SCI-D SCI-D - Neurosciences Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=783 The Cranial Circumference in Autism [Texte imprimé et/ou numérique] / Michele ZAPPELLA, Auteur . - 2005 . - p.91-100.
Langues : Anglais (eng)
Mots-clés : Périmetre cranien Syndrome Sotos Neurofibromatose de type 1 Hypomélanose de Ito Syndrome des hamartomes par mutation du gène PTEN Index. décimale : SCI-D SCI-D - Neurosciences Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=783 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire The Developing Mind / Daniel J. SIEGEL
Titre : The Developing Mind : How Relationships and the Brain Interact to Shape Who We Are Type de document : Texte imprimé et/ou numérique Auteurs : Daniel J. SIEGEL, Auteur Mention d'édition : Second Edition Editeur : New-York [Etats-Unis] : Guilford Press Année de publication : 2012 Importance : 506 p. Présentation : ill. Format : 16,5cm x 24cm x 3,8cm ISBN/ISSN/EAN : 978-1-4625-0390-2 Note générale : Bibliogr., Index, Glossaire Langues : Anglais (eng) Index. décimale : SCI-D SCI-D - Neurosciences Résumé : This bestselling book put the field of interpersonal neurobiology on the map for many tens of thousands of readers. Daniel J. Siegel goes beyond the nature and nurture divisions that traditionally have constrained much of our thinking about development, exploring the role of interpersonal experiences in forging key connections in the brain. He presents a groundbreaking integrative framework for understanding the emergence of the growing, feeling, communicating mind. Illuminating how and why interpersonal neurobiology matters, this book is essential reading for clinicians, educators, researchers, and students interested in promoting healthy development and resilience across the lifespan.
New to This Edition
Incorporates significant scientific and technical advances.
Expanded discussions of cutting-edge topics, including neuroplasticity, epigenetics, mindfulness, and the neural correlates of consciousness.
Useful pedagogical features, such as diagrams and an extensive glossary.
Epilogue on domains of integration—specific pathways to well-being and therapeutic change. [Résumé d'Auteur/Editeur]Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=185 The Developing Mind : How Relationships and the Brain Interact to Shape Who We Are [Texte imprimé et/ou numérique] / Daniel J. SIEGEL, Auteur . - Second Edition . - New-York [Etats-Unis] : Guilford Press, 2012 . - 506 p. : ill. ; 16,5cm x 24cm x 3,8cm.
ISBN : 978-1-4625-0390-2
Bibliogr., Index, Glossaire
Langues : Anglais (eng)
Index. décimale : SCI-D SCI-D - Neurosciences Résumé : This bestselling book put the field of interpersonal neurobiology on the map for many tens of thousands of readers. Daniel J. Siegel goes beyond the nature and nurture divisions that traditionally have constrained much of our thinking about development, exploring the role of interpersonal experiences in forging key connections in the brain. He presents a groundbreaking integrative framework for understanding the emergence of the growing, feeling, communicating mind. Illuminating how and why interpersonal neurobiology matters, this book is essential reading for clinicians, educators, researchers, and students interested in promoting healthy development and resilience across the lifespan.
New to This Edition
Incorporates significant scientific and technical advances.
Expanded discussions of cutting-edge topics, including neuroplasticity, epigenetics, mindfulness, and the neural correlates of consciousness.
Useful pedagogical features, such as diagrams and an extensive glossary.
Epilogue on domains of integration—specific pathways to well-being and therapeutic change. [Résumé d'Auteur/Editeur]Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=185 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité DOC0002284 SCI-D SIE Livre Centre d'Information et de Documentation du CRA Rhône-Alpes SCI - Disciplines Scientifiques Disponible Les abonnés qui ont emprunté ce document ont également emprunté :
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