161 recherche sur le mot-clé 'Auditory'

Auditory Attention Deployment in Young Adults with Autism Spectrum Disorder / Katherine A. EMMONS in Journal of Autism and Developmental Disorders, 52-4 (April 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1752-1761 Titre : Auditory Attention Deployment in Young Adults with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Katherine A. EMMONS, Auteur ; Adrian KC LEE, Auteur ; Annette ESTES, Auteur ; Stephen R. DAGER, Auteur ; Eric LARSON, Auteur ; Daniel R. MCCLOY, Auteur ; Tanya ST JOHN, Auteur ; Bonnie K. LAU, Auteur Article en page(s) : p.1752-1761 Langues : Anglais (eng) Mots-clés : Attention  Auditory Perception  Autism Spectrum Disorder  Female  Humans  Male  Speech  Voice  Young Adult  Auditory attention  Auditory processing  Selective attention  Speech perception Index. décimale : PER Périodiques Résumé : Difficulty listening in noisy environments is a common complaint of individuals with autism spectrum disorder (ASD). However, the mechanisms underlying such auditory processing challenges are unknown. This preliminary study investigated auditory attention deployment in adults with ASD. Participants were instructed to maintain or switch attention between two simultaneous speech streams in three conditions: location (co-located versus+30° separation), voice (same voice versus male-female contrast), and both cues together. Results showed that individuals with ASD can selectively direct attention using location or voice cues, but performance was best when both cues were present. In comparison to neurotypical adults, overall performance was less accurate across all conditions. These findings warrant further investigation into auditory attention deployment differences in individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05076-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 [article] Auditory Attention Deployment in Young Adults with Autism Spectrum Disorder [texte imprimé] / Katherine A. EMMONS, Auteur ; Adrian KC LEE, Auteur ; Annette ESTES, Auteur ; Stephen R. DAGER, Auteur ; Eric LARSON, Auteur ; Daniel R. MCCLOY, Auteur ; Tanya ST JOHN, Auteur ; Bonnie K. LAU, Auteur . - p.1752-1761. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1752-1761 Mots-clés : Attention  Auditory Perception  Autism Spectrum Disorder  Female  Humans  Male  Speech  Voice  Young Adult  Auditory attention  Auditory processing  Selective attention  Speech perception Index. décimale : PER Périodiques Résumé : Difficulty listening in noisy environments is a common complaint of individuals with autism spectrum disorder (ASD). However, the mechanisms underlying such auditory processing challenges are unknown. This preliminary study investigated auditory attention deployment in adults with ASD. Participants were instructed to maintain or switch attention between two simultaneous speech streams in three conditions: location (co-located versus+30° separation), voice (same voice versus male-female contrast), and both cues together. Results showed that individuals with ASD can selectively direct attention using location or voice cues, but performance was best when both cues were present. In comparison to neurotypical adults, overall performance was less accurate across all conditions. These findings warrant further investigation into auditory attention deployment differences in individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05076-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476

Auditory processing in rodent models of autism: a systematic review / Maya WILDE in Journal of Neurodevelopmental Disorders, 14 (2022)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 14 (2022) Titre : Auditory processing in rodent models of autism: a systematic review Type de document : texte imprimé Auteurs : Maya WILDE, Auteur ; Lena CONSTANTIN, Auteur ; Peter R THORNE, Auteur ; Johanna M MONTGOMERY, Auteur ; Ethan K SCOTT, Auteur ; Juliette E CHEYNE, Auteur Langues : Anglais (eng) Mots-clés : Animals  Auditory Perception/physiology  Autistic Disorder  Electroencephalography/methods  Evoked Potentials, Auditory, Brain Stem  Humans  Mice  Rats  Rodentia  Auditory  Auditory brainstem recordings  Autism spectrum disorder  Cortical event-related potentials  Rodent models Index. décimale : PER Périodiques Résumé : Autism is a complex condition with many traits, including differences in auditory sensitivity. Studies in human autism are plagued by the difficulty of controlling for aetiology, whereas studies in individual rodent models cannot represent the full spectrum of human autism. This systematic review compares results in auditory studies across a wide range of established rodent models of autism to mimic the wide range of aetiologies in the human population. A search was conducted in the PubMed and Web of Science databases to find primary research articles in mouse or rat models of autism which investigate central auditory processing. A total of 88 studies were included. These used non-invasive measures of auditory function, such as auditory brainstem response recordings, cortical event-related potentials, electroencephalography, and behavioural tests, which are translatable to human studies. They also included invasive measures, such as electrophysiology and histology, which shed insight on the origins of the phenotypes found in the non-invasive studies. The most consistent results across these studies were increased latency of the N1 peak of event-related potentials, decreased power and coherence of gamma activity in the auditory cortex, and increased auditory startle responses to high sound levels. Invasive studies indicated loss of subcortical inhibitory neurons, hyperactivity in the lateral superior olive and auditory thalamus, and reduced specificity of responses in the auditory cortex. This review compares the auditory phenotypes across rodent models and highlights those that mimic findings in human studies, providing a framework and avenues for future studies to inform understanding of the auditory system in autism. En ligne : https://dx.doi.org/10.1186/s11689-022-09458-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=574 [article] Auditory processing in rodent models of autism: a systematic review [texte imprimé] / Maya WILDE, Auteur ; Lena CONSTANTIN, Auteur ; Peter R THORNE, Auteur ; Johanna M MONTGOMERY, Auteur ; Ethan K SCOTT, Auteur ; Juliette E CHEYNE, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 14 (2022) Mots-clés : Animals  Auditory Perception/physiology  Autistic Disorder  Electroencephalography/methods  Evoked Potentials, Auditory, Brain Stem  Humans  Mice  Rats  Rodentia  Auditory  Auditory brainstem recordings  Autism spectrum disorder  Cortical event-related potentials  Rodent models Index. décimale : PER Périodiques Résumé : Autism is a complex condition with many traits, including differences in auditory sensitivity. Studies in human autism are plagued by the difficulty of controlling for aetiology, whereas studies in individual rodent models cannot represent the full spectrum of human autism. This systematic review compares results in auditory studies across a wide range of established rodent models of autism to mimic the wide range of aetiologies in the human population. A search was conducted in the PubMed and Web of Science databases to find primary research articles in mouse or rat models of autism which investigate central auditory processing. A total of 88 studies were included. These used non-invasive measures of auditory function, such as auditory brainstem response recordings, cortical event-related potentials, electroencephalography, and behavioural tests, which are translatable to human studies. They also included invasive measures, such as electrophysiology and histology, which shed insight on the origins of the phenotypes found in the non-invasive studies. The most consistent results across these studies were increased latency of the N1 peak of event-related potentials, decreased power and coherence of gamma activity in the auditory cortex, and increased auditory startle responses to high sound levels. Invasive studies indicated loss of subcortical inhibitory neurons, hyperactivity in the lateral superior olive and auditory thalamus, and reduced specificity of responses in the auditory cortex. This review compares the auditory phenotypes across rodent models and highlights those that mimic findings in human studies, providing a framework and avenues for future studies to inform understanding of the auditory system in autism. En ligne : https://dx.doi.org/10.1186/s11689-022-09458-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=574

Probing a neural unreliability account of auditory sensory processing atypicalities in Rett Syndrome / Tufikameni BRIMA in Journal of Neurodevelopmental Disorders, 16 (2024)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 16 (2024) Titre : Probing a neural unreliability account of auditory sensory processing atypicalities in Rett Syndrome Type de document : texte imprimé Auteurs : Tufikameni BRIMA, Auteur ; Shlomit BEKER, Auteur ; Kevin D. PRINSLOO, Auteur ; John S. BUTLER, Auteur ; Aleksandra DJUKIC, Auteur ; Edward G. FREEDMAN, Auteur ; Sophie MOLHOLM, Auteur ; John J. FOXE, Auteur Langues : Anglais (eng) Mots-clés : Humans  Rett Syndrome/physiopathology/complications  Adolescent  Female  Evoked Potentials, Auditory/physiology  Child  Young Adult  Electroencephalography  Auditory Perception/physiology  Reproducibility of Results  Acoustic Stimulation  Male  Signal-To-Noise Ratio  Adult  Auditory Evoked Potential  AEP  Auditory discrimination  Denoising Source Separation (DSS)  Eeg  Event-related potential  ERP  Females  High-density electrical mapping  Inter-Trial Phase Coherence (ITPC)  Inter-trial variability (ITV)  Neurodevelopmental disorder  Rett Syndrome Severity Scale (RSSS)  Signal-noise ratio (SNR)  X-linked mutation  MECP2  to the results of this study. Index. décimale : PER Périodiques Résumé : BACKGROUND: In the search for objective tools to quantify neural function in Rett Syndrome (RTT), which are crucial in the evaluation of therapeutic efficacy in clinical trials, recordings of sensory-perceptual functioning using event-related potential (ERP) approaches have emerged as potentially powerful tools. Considerable work points to highly anomalous auditory evoked potentials (AEPs) in RTT. However, an assumption of the typical signal-averaging method used to derive these measures is "stationarity" of the underlying responses - i.e. neural responses to each input are highly stereotyped. An alternate possibility is that responses to repeated stimuli are highly variable in RTT. If so, this will significantly impact the validity of assumptions about underlying neural dysfunction, and likely lead to overestimation of underlying neuropathology. To assess this possibility, analyses at the single-trial level assessing signal-to-noise ratios (SNR), inter-trial variability (ITV) and inter-trial phase coherence (ITPC) are necessary. METHODS: AEPs were recorded to simple 100 Hz tones from 18 RTT and 27 age-matched controls (Ages: 6-22 years). We applied standard AEP averaging, as well as measures of neuronal reliability at the single-trial level (i.e. SNR, ITV, ITPC). To separate signal-carrying components from non-neural noise sources, we also applied a denoising source separation (DSS) algorithm and then repeated the reliability measures. RESULTS: Substantially increased ITV, lower SNRs, and reduced ITPC were observed in auditory responses of RTT participants, supporting a "neural unreliability" account. Application of the DSS technique made it clear that non-neural noise sources contribute to overestimation of the extent of processing deficits in RTT. Post-DSS, ITV measures were substantially reduced, so much so that pre-DSS ITV differences between RTT and TD populations were no longer detected. In the case of SNR and ITPC, DSS substantially improved these estimates in the RTT population, but robust differences between RTT and TD were still fully evident. CONCLUSIONS: To accurately represent the degree of neural dysfunction in RTT using the ERP technique, a consideration of response reliability at the single-trial level is highly advised. Non-neural sources of noise lead to overestimation of the degree of pathological processing in RTT, and denoising source separation techniques during signal processing substantially ameliorate this issue. En ligne : https://dx.doi.org/10.1186/s11689-024-09544-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=575 [article] Probing a neural unreliability account of auditory sensory processing atypicalities in Rett Syndrome [texte imprimé] / Tufikameni BRIMA, Auteur ; Shlomit BEKER, Auteur ; Kevin D. PRINSLOO, Auteur ; John S. BUTLER, Auteur ; Aleksandra DJUKIC, Auteur ; Edward G. FREEDMAN, Auteur ; Sophie MOLHOLM, Auteur ; John J. FOXE, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 16 (2024) Mots-clés : Humans  Rett Syndrome/physiopathology/complications  Adolescent  Female  Evoked Potentials, Auditory/physiology  Child  Young Adult  Electroencephalography  Auditory Perception/physiology  Reproducibility of Results  Acoustic Stimulation  Male  Signal-To-Noise Ratio  Adult  Auditory Evoked Potential  AEP  Auditory discrimination  Denoising Source Separation (DSS)  Eeg  Event-related potential  ERP  Females  High-density electrical mapping  Inter-Trial Phase Coherence (ITPC)  Inter-trial variability (ITV)  Neurodevelopmental disorder  Rett Syndrome Severity Scale (RSSS)  Signal-noise ratio (SNR)  X-linked mutation  MECP2  to the results of this study. Index. décimale : PER Périodiques Résumé : BACKGROUND: In the search for objective tools to quantify neural function in Rett Syndrome (RTT), which are crucial in the evaluation of therapeutic efficacy in clinical trials, recordings of sensory-perceptual functioning using event-related potential (ERP) approaches have emerged as potentially powerful tools. Considerable work points to highly anomalous auditory evoked potentials (AEPs) in RTT. However, an assumption of the typical signal-averaging method used to derive these measures is "stationarity" of the underlying responses - i.e. neural responses to each input are highly stereotyped. An alternate possibility is that responses to repeated stimuli are highly variable in RTT. If so, this will significantly impact the validity of assumptions about underlying neural dysfunction, and likely lead to overestimation of underlying neuropathology. To assess this possibility, analyses at the single-trial level assessing signal-to-noise ratios (SNR), inter-trial variability (ITV) and inter-trial phase coherence (ITPC) are necessary. METHODS: AEPs were recorded to simple 100 Hz tones from 18 RTT and 27 age-matched controls (Ages: 6-22 years). We applied standard AEP averaging, as well as measures of neuronal reliability at the single-trial level (i.e. SNR, ITV, ITPC). To separate signal-carrying components from non-neural noise sources, we also applied a denoising source separation (DSS) algorithm and then repeated the reliability measures. RESULTS: Substantially increased ITV, lower SNRs, and reduced ITPC were observed in auditory responses of RTT participants, supporting a "neural unreliability" account. Application of the DSS technique made it clear that non-neural noise sources contribute to overestimation of the extent of processing deficits in RTT. Post-DSS, ITV measures were substantially reduced, so much so that pre-DSS ITV differences between RTT and TD populations were no longer detected. In the case of SNR and ITPC, DSS substantially improved these estimates in the RTT population, but robust differences between RTT and TD were still fully evident. CONCLUSIONS: To accurately represent the degree of neural dysfunction in RTT using the ERP technique, a consideration of response reliability at the single-trial level is highly advised. Non-neural sources of noise lead to overestimation of the degree of pathological processing in RTT, and denoising source separation techniques during signal processing substantially ameliorate this issue. En ligne : https://dx.doi.org/10.1186/s11689-024-09544-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=575

Attenuated processing of vowels in the left temporal cortex predicts speech-in-noise perception deficit in children with autism / Kirill A. FADEEV in Journal of Neurodevelopmental Disorders, 16 (2024)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 16 (2024) Titre : Attenuated processing of vowels in the left temporal cortex predicts speech-in-noise perception deficit in children with autism Type de document : texte imprimé Auteurs : Kirill A. FADEEV, Auteur ; Ilacai V. ROMERO REYES, Auteur ; Dzerassa E. GOIAEVA, Auteur ; Tatiana S. OBUKHOVA, Auteur ; Tatiana M. OVSIANNIKOVA, Auteur ; Andrey O. PROKOFYEV, Auteur ; Anna M. RYTIKOVA, Auteur ; Artem Y. NOVIKOV, Auteur ; Vladimir V. KOZUNOV, Auteur ; Tatiana A. STROGANOVA, Auteur ; Elena V. OREKHOVA, Auteur Langues : Anglais (eng) Mots-clés : Humans  Male  Speech Perception/physiology  Magnetoencephalography  Child  Temporal Lobe/physiopathology  Noise  Acoustic Stimulation  Evoked Potentials, Auditory/physiology  Autism Spectrum Disorder/physiopathology/complications  Adolescent  Auditory Cortex/physiopathology  Autistic Disorder/physiopathology/complications  Auditory processing disorder  Autism spectrum disorder (ASD)  Children  Formant structure  Magnetoencephalography (MEG)  Periodicity pitch  Speech-in-noise perception  Sustained processing negativity (SPN)  Vowels  of the Moscow State University of Psychology and Education approved this  investigation. All children gave verbal consent to participate in the study and  their caregivers gave written consent to participate. Consent for publication:  All children gave verbal consent to participate in the study and their caregivers  gave written consent for publication of anonymized data. Competing interests: The  authors declare no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: Difficulties with speech-in-noise perception in autism spectrum disorders (ASD) may be associated with impaired analysis of speech sounds, such as vowels, which represent the fundamental phoneme constituents of human speech. Vowels elicit early (< 100 ms) sustained processing negativity (SPN) in the auditory cortex that reflects the detection of an acoustic pattern based on the presence of formant structure and/or periodic envelope information (f0) and its transformation into an auditory "object". METHODS: We used magnetoencephalography (MEG) and individual brain models to investigate whether SPN is altered in children with ASD and whether this deficit is associated with impairment in their ability to perceive speech in the background of noise. MEG was recorded while boys with ASD and typically developing boys passively listened to sounds that differed in the presence/absence of f0 periodicity and formant structure. Word-in-noise perception was assessed in the separate psychoacoustic experiment using stationary and amplitude modulated noise with varying signal-to-noise ratio. RESULTS: SPN was present in both groups with similarly early onset. In children with ASD, SPN associated with processing formant structure was reduced predominantly in the cortical areas lateral to and medial to the primary auditory cortex, starting at ~ 150-200 ms after the stimulus onset. In the left hemisphere, this deficit correlated with impaired ability of children with ASD to recognize words in amplitude-modulated noise, but not in stationary noise. CONCLUSIONS: These results suggest that perceptual grouping of vowel formants into phonemes is impaired in children with ASD and that, in the left hemisphere, this deficit contributes to their difficulties with speech perception in fluctuating background noise. En ligne : https://dx.doi.org/10.1186/s11689-024-09585-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576 [article] Attenuated processing of vowels in the left temporal cortex predicts speech-in-noise perception deficit in children with autism [texte imprimé] / Kirill A. FADEEV, Auteur ; Ilacai V. ROMERO REYES, Auteur ; Dzerassa E. GOIAEVA, Auteur ; Tatiana S. OBUKHOVA, Auteur ; Tatiana M. OVSIANNIKOVA, Auteur ; Andrey O. PROKOFYEV, Auteur ; Anna M. RYTIKOVA, Auteur ; Artem Y. NOVIKOV, Auteur ; Vladimir V. KOZUNOV, Auteur ; Tatiana A. STROGANOVA, Auteur ; Elena V. OREKHOVA, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 16 (2024) Mots-clés : Humans  Male  Speech Perception/physiology  Magnetoencephalography  Child  Temporal Lobe/physiopathology  Noise  Acoustic Stimulation  Evoked Potentials, Auditory/physiology  Autism Spectrum Disorder/physiopathology/complications  Adolescent  Auditory Cortex/physiopathology  Autistic Disorder/physiopathology/complications  Auditory processing disorder  Autism spectrum disorder (ASD)  Children  Formant structure  Magnetoencephalography (MEG)  Periodicity pitch  Speech-in-noise perception  Sustained processing negativity (SPN)  Vowels  of the Moscow State University of Psychology and Education approved this  investigation. All children gave verbal consent to participate in the study and  their caregivers gave written consent to participate. Consent for publication:  All children gave verbal consent to participate in the study and their caregivers  gave written consent for publication of anonymized data. Competing interests: The  authors declare no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: Difficulties with speech-in-noise perception in autism spectrum disorders (ASD) may be associated with impaired analysis of speech sounds, such as vowels, which represent the fundamental phoneme constituents of human speech. Vowels elicit early (< 100 ms) sustained processing negativity (SPN) in the auditory cortex that reflects the detection of an acoustic pattern based on the presence of formant structure and/or periodic envelope information (f0) and its transformation into an auditory "object". METHODS: We used magnetoencephalography (MEG) and individual brain models to investigate whether SPN is altered in children with ASD and whether this deficit is associated with impairment in their ability to perceive speech in the background of noise. MEG was recorded while boys with ASD and typically developing boys passively listened to sounds that differed in the presence/absence of f0 periodicity and formant structure. Word-in-noise perception was assessed in the separate psychoacoustic experiment using stationary and amplitude modulated noise with varying signal-to-noise ratio. RESULTS: SPN was present in both groups with similarly early onset. In children with ASD, SPN associated with processing formant structure was reduced predominantly in the cortical areas lateral to and medial to the primary auditory cortex, starting at ~ 150-200 ms after the stimulus onset. In the left hemisphere, this deficit correlated with impaired ability of children with ASD to recognize words in amplitude-modulated noise, but not in stationary noise. CONCLUSIONS: These results suggest that perceptual grouping of vowel formants into phonemes is impaired in children with ASD and that, in the left hemisphere, this deficit contributes to their difficulties with speech perception in fluctuating background noise. En ligne : https://dx.doi.org/10.1186/s11689-024-09585-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576

Brief Report: Atypical Neuromagnetic Responses to Illusory Auditory Pitch in Children with Autism Spectrum Disorders / Jon BROCK in Journal of Autism and Developmental Disorders, 43-11 (November 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2726-2731 Titre : Brief Report: Atypical Neuromagnetic Responses to Illusory Auditory Pitch in Children with Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Jon BROCK, Auteur ; Samantha BZISHVILI, Auteur ; Melanie REID, Auteur ; Michael HAUTUS, Auteur ; Blake W. JOHNSON, Auteur Article en page(s) : p.2726-2731 Langues : Anglais (eng) Mots-clés : Auditory evoked potentials  Auditory perception  Autism  MEG Index. décimale : PER Périodiques Résumé : Atypical auditory perception is a widely recognised but poorly understood feature of autism. In the current study, we used magnetoencephalography to measure the brain responses of 10 autistic children as they listened passively to dichotic pitch stimuli, in which an illusory tone is generated by sub-millisecond inter-aural timing differences in white noise. Relative to control stimuli that contain no inter-aural timing differences, dichotic pitch stimuli typically elicit an object related negativity (ORN) response, associated with the perceptual segregation of the tone and the carrier noise into distinct auditory objects. Autistic children failed to demonstrate an ORN, suggesting a failure of segregation; however, comparison with the ORNs of age-matched typically developing controls narrowly failed to attain significance. More striking, the autistic children demonstrated a significant differential response to the pitch stimulus, peaking at around 50 ms. This was not present in the control group, nor has it been found in other groups tested using similar stimuli. This response may be a neural signature of atypical processing of pitch in at least some autistic individuals. En ligne : http://dx.doi.org/10.1007/s10803-013-1805-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217 [article] Brief Report: Atypical Neuromagnetic Responses to Illusory Auditory Pitch in Children with Autism Spectrum Disorders [texte imprimé] / Jon BROCK, Auteur ; Samantha BZISHVILI, Auteur ; Melanie REID, Auteur ; Michael HAUTUS, Auteur ; Blake W. JOHNSON, Auteur . - p.2726-2731. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2726-2731 Mots-clés : Auditory evoked potentials  Auditory perception  Autism  MEG Index. décimale : PER Périodiques Résumé : Atypical auditory perception is a widely recognised but poorly understood feature of autism. In the current study, we used magnetoencephalography to measure the brain responses of 10 autistic children as they listened passively to dichotic pitch stimuli, in which an illusory tone is generated by sub-millisecond inter-aural timing differences in white noise. Relative to control stimuli that contain no inter-aural timing differences, dichotic pitch stimuli typically elicit an object related negativity (ORN) response, associated with the perceptual segregation of the tone and the carrier noise into distinct auditory objects. Autistic children failed to demonstrate an ORN, suggesting a failure of segregation; however, comparison with the ORNs of age-matched typically developing controls narrowly failed to attain significance. More striking, the autistic children demonstrated a significant differential response to the pitch stimulus, peaking at around 50 ms. This was not present in the control group, nor has it been found in other groups tested using similar stimuli. This response may be a neural signature of atypical processing of pitch in at least some autistic individuals. En ligne : http://dx.doi.org/10.1007/s10803-013-1805-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217

Brief Report: Preliminary Reliability, Construct Validity and Standardization of the Auditory Behavior Questionnaire (ABQ) for Children with Autism Spectrum Disorders / Kelsey EGELHOFF in Journal of Autism and Developmental Disorders, 43-4 (April 2013)  

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Correlations Between Audiovisual Temporal Processing and Sensory Responsiveness in Adolescents with Autistic Traits / Han-Yu ZHOU in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

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Deficits in skilled motor and auditory learning in a rat model of Rett syndrome / Katherine S. ADCOCK in Journal of Neurodevelopmental Disorders, 12 (2020)  

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Degraded inferior colliculus responses to complex sounds in prenatally exposed VPA rats / Yuko TAMAOKI in Journal of Neurodevelopmental Disorders, 16 (2024)  

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Early differences in auditory processing relate to Autism Spectrum Disorder traits in infants with Neurofibromatosis Type I / Jannath BEGUM-ALI in Journal of Neurodevelopmental Disorders, 13 (2021)  

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