86 recherche sur le mot-clé 'Cortical-plasticity'

Topographic differences of slow event-related brain potentials in blind and sighted adult human subjects during haptic mental rotation / Frank ROSLER in Cognitive Brain Research, 1-3 (October 1993)

Public ISBD [article]  inCognitive Brain Research > 1-3 (October 1993) . - p.145-159 Titre : Topographic differences of slow event-related brain potentials in blind and sighted adult human subjects during haptic mental rotation Type de document : texte imprimé Auteurs : Frank ROSLER, Auteur ; Brigitte RODER, Auteur ; Martin HEIL, Auteur ; Erwin HENNIGHAUSEN, Auteur Année de publication : 1993 Article en page(s) : p.145-159 Langues : Anglais (eng) Mots-clés : Blindness Electroencephalogram Slow-wave Functional-organization-of-the-cortex Cortical-plasticity Haptic-mental-rotation Cognition Index. décimale : PER Périodiques Résumé : Twelve blindfolded sighted, nine congenitally blind, and seven adventitiously blind subjects were tested in a haptic mental rotation task while slow event-related potentials in the EEG were recorded from 17 scalp locations. The overall topography of the slow wave pattern which prevailed during the task differed for sighted and for blind, but not for congenitally and adventitiously blind subjects. While the tactile stimuli were encoded, the blind showed a pronounced occipital and the sighted a pronounced frontal activation. The task-specific amplitude increment of a negative slow wave which can be understood as a manifestation of the process of mental rotation proper, showed a different topography for sighted and for blind subjects too. It had its maximum over central to parietal cortical areas in both groups, but it extended more towards occipital regions in the blind. In both groups, the effects were very similar to those observed in former studies with visual versions of the mental rotation task, i.e. the slow wave amplitude over central to parietal areas increased monotonously with an increasing angular disparity of the two stimuli to be compared. These results are discussed with respect to the question of whether visual deprivation in the blind can cause a reorganization of cortical representational maps. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=781 [article] Topographic differences of slow event-related brain potentials in blind and sighted adult human subjects during haptic mental rotation [texte imprimé] / Frank ROSLER, Auteur ; Brigitte RODER, Auteur ; Martin HEIL, Auteur ; Erwin HENNIGHAUSEN, Auteur . - 1993 . - p.145-159. Langues : Anglais (eng) in Cognitive Brain Research > 1-3 (October 1993) . - p.145-159 Mots-clés : Blindness Electroencephalogram Slow-wave Functional-organization-of-the-cortex Cortical-plasticity Haptic-mental-rotation Cognition Index. décimale : PER Périodiques Résumé : Twelve blindfolded sighted, nine congenitally blind, and seven adventitiously blind subjects were tested in a haptic mental rotation task while slow event-related potentials in the EEG were recorded from 17 scalp locations. The overall topography of the slow wave pattern which prevailed during the task differed for sighted and for blind, but not for congenitally and adventitiously blind subjects. While the tactile stimuli were encoded, the blind showed a pronounced occipital and the sighted a pronounced frontal activation. The task-specific amplitude increment of a negative slow wave which can be understood as a manifestation of the process of mental rotation proper, showed a different topography for sighted and for blind subjects too. It had its maximum over central to parietal cortical areas in both groups, but it extended more towards occipital regions in the blind. In both groups, the effects were very similar to those observed in former studies with visual versions of the mental rotation task, i.e. the slow wave amplitude over central to parietal areas increased monotonously with an increasing angular disparity of the two stimuli to be compared. These results are discussed with respect to the question of whether visual deprivation in the blind can cause a reorganization of cortical representational maps. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=781

Vagus nerve stimulation as a potential adjuvant to behavioral therapy for autism and other neurodevelopmental disorders / Crystal T. ENGINEER in Journal of Neurodevelopmental Disorders, 9-1 (December 2017)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 9-1 (December 2017) . - p.20 Titre : Vagus nerve stimulation as a potential adjuvant to behavioral therapy for autism and other neurodevelopmental disorders Type de document : texte imprimé Auteurs : Crystal T. ENGINEER, Auteur ; Seth A. HAYS, Auteur ; Michael P. KILGARD, Auteur Article en page(s) : p.20 Langues : Anglais (eng) Mots-clés : Autism  Cortex  Cortical reorganization  Plasticity  Vagal nerve Index. décimale : PER Périodiques Résumé : BACKGROUND: Many children with autism and other neurodevelopmental disorders undergo expensive, time-consuming behavioral interventions that often yield only modest improvements. The development of adjunctive interventions that can increase the benefit of rehabilitation therapies is essential in order to improve the lives of individuals with neurodevelopmental disorders. MAIN TEXT: Vagus nerve stimulation (VNS) is an FDA approved therapy that is safe and effective in reducing seizure frequency and duration in individuals with epilepsy. Individuals with neurodevelopmental disorders often exhibit decreased vagal tone, and studies indicate that VNS can be used to overcome an insufficient vagal response. Multiple studies have also documented significant improvements in quality of life after VNS therapy in individuals with neurodevelopmental disorders. Moreover, recent findings indicate that VNS significantly enhances the benefits of rehabilitative training in animal models and patients, leading to greater recovery in a variety of neurological diseases. Here, we review these findings and provide a discussion of how VNS paired with rehabilitation may yield benefits in the context of neurodevelopmental disorders. CONCLUSIONS: VNS paired with behavioral therapy may represent a potential new approach to enhance rehabilitation that could significantly improve the outcomes of individuals with neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1186/s11689-017-9203-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=350 [article] Vagus nerve stimulation as a potential adjuvant to behavioral therapy for autism and other neurodevelopmental disorders [texte imprimé] / Crystal T. ENGINEER, Auteur ; Seth A. HAYS, Auteur ; Michael P. KILGARD, Auteur . - p.20. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 9-1 (December 2017) . - p.20 Mots-clés : Autism  Cortex  Cortical reorganization  Plasticity  Vagal nerve Index. décimale : PER Périodiques Résumé : BACKGROUND: Many children with autism and other neurodevelopmental disorders undergo expensive, time-consuming behavioral interventions that often yield only modest improvements. The development of adjunctive interventions that can increase the benefit of rehabilitation therapies is essential in order to improve the lives of individuals with neurodevelopmental disorders. MAIN TEXT: Vagus nerve stimulation (VNS) is an FDA approved therapy that is safe and effective in reducing seizure frequency and duration in individuals with epilepsy. Individuals with neurodevelopmental disorders often exhibit decreased vagal tone, and studies indicate that VNS can be used to overcome an insufficient vagal response. Multiple studies have also documented significant improvements in quality of life after VNS therapy in individuals with neurodevelopmental disorders. Moreover, recent findings indicate that VNS significantly enhances the benefits of rehabilitative training in animal models and patients, leading to greater recovery in a variety of neurological diseases. Here, we review these findings and provide a discussion of how VNS paired with rehabilitation may yield benefits in the context of neurodevelopmental disorders. CONCLUSIONS: VNS paired with behavioral therapy may represent a potential new approach to enhance rehabilitation that could significantly improve the outcomes of individuals with neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1186/s11689-017-9203-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=350

Altered Cortical Thickness and Tract Integrity of the Mirror Neuron System and Associated Social Communication in Autism Spectrum Disorder / Hsiang-Yun CHIEN in Autism Research, 8-6 (December 2015)  

Public ISBD [article]  inAutism Research > 8-6 (December 2015) . - p.694-708 Titre : Altered Cortical Thickness and Tract Integrity of the Mirror Neuron System and Associated Social Communication in Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Hsiang-Yun CHIEN, Auteur ; Susan Shur-Fen GAU, Auteur ; Yung-Chin HSU, Auteur ; Yu-Jen CHEN, Auteur ; Yu-Chun LO, Auteur ; Yao-Chia SHIH, Auteur ; Wen-Yih Isaac TSENG, Auteur Article en page(s) : p.694-708 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  mirror neuron system  diffusion spectrum imaging  cortical thickness  white matter integrity  tractography  social communication Index. décimale : PER Périodiques Résumé : Previous studies using neural activity recording and neuroimaging techniques have reported functional deficits in the mirror neuron system (MNS) for individuals with autism spectrum disorder (ASD). However, a few studies focusing on gray and white matter structures of the MNS have yielded inconsistent results. The current study recruited adolescents and young adults with ASD (aged 15–26 years) and age-matched typically developing (TD) controls (aged 14–25 years). The cortical thickness (CT) and microstructural integrity of the tracts connecting the regions forming the classical MNS were investigated. High-resolution T1-weighted imaging and diffusion spectrum imaging were performed to quantify the CT and tract integrity, respectively. The structural covariance of the CT of the MNS regions revealed a weaker coordination of the MNS network in ASD. A strong correlation was found between the integrity of the right frontoparietal tracts and the social communication subscores measured by the Chinese version of the Social Communication Questionnaire. The results showed that there were no significant mean differences in the CTs and tract integrity between the ASD and TD groups, but revealed a moderate or even reverse age effect on the frontal MNS structures in ASD. In conclusion, aberrant structural coordination may be an underlying factor affecting the function of the MNS in ASD patients. The association between the right frontoparietal tracts and social communication performance implies a neural correlate of communication processing in the autistic brain. This study provides evidence of abnormal MNS structures and their influence on social communication in individuals with ASD. Autism Res 2015, 8: 694–708. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1484 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Altered Cortical Thickness and Tract Integrity of the Mirror Neuron System and Associated Social Communication in Autism Spectrum Disorder [texte imprimé] / Hsiang-Yun CHIEN, Auteur ; Susan Shur-Fen GAU, Auteur ; Yung-Chin HSU, Auteur ; Yu-Jen CHEN, Auteur ; Yu-Chun LO, Auteur ; Yao-Chia SHIH, Auteur ; Wen-Yih Isaac TSENG, Auteur . - p.694-708. Langues : Anglais (eng) in Autism Research > 8-6 (December 2015) . - p.694-708 Mots-clés : autism spectrum disorder  mirror neuron system  diffusion spectrum imaging  cortical thickness  white matter integrity  tractography  social communication Index. décimale : PER Périodiques Résumé : Previous studies using neural activity recording and neuroimaging techniques have reported functional deficits in the mirror neuron system (MNS) for individuals with autism spectrum disorder (ASD). However, a few studies focusing on gray and white matter structures of the MNS have yielded inconsistent results. The current study recruited adolescents and young adults with ASD (aged 15–26 years) and age-matched typically developing (TD) controls (aged 14–25 years). The cortical thickness (CT) and microstructural integrity of the tracts connecting the regions forming the classical MNS were investigated. High-resolution T1-weighted imaging and diffusion spectrum imaging were performed to quantify the CT and tract integrity, respectively. The structural covariance of the CT of the MNS regions revealed a weaker coordination of the MNS network in ASD. A strong correlation was found between the integrity of the right frontoparietal tracts and the social communication subscores measured by the Chinese version of the Social Communication Questionnaire. The results showed that there were no significant mean differences in the CTs and tract integrity between the ASD and TD groups, but revealed a moderate or even reverse age effect on the frontal MNS structures in ASD. In conclusion, aberrant structural coordination may be an underlying factor affecting the function of the MNS in ASD patients. The association between the right frontoparietal tracts and social communication performance implies a neural correlate of communication processing in the autistic brain. This study provides evidence of abnormal MNS structures and their influence on social communication in individuals with ASD. Autism Res 2015, 8: 694–708. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1484 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Altered subcortical and cortical brain morphology in adult women with 47,XXX: a 7-Tesla magnetic resonance imaging study / Chaira SERRARENS in Journal of Neurodevelopmental Disorders, 14 (2022)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 14 (2022) Titre : Altered subcortical and cortical brain morphology in adult women with 47,XXX: a 7-Tesla magnetic resonance imaging study Type de document : texte imprimé Auteurs : Chaira SERRARENS, Auteur ; Maarten OTTER, Auteur ; Bea C.M. CAMPFORTS, Auteur ; Constance T.R.M. STUMPEL, Auteur ; Henk JANSMA, Auteur ; Therese A.M.J. VAN AMELSVOORT, Auteur ; Claudia VINGERHOETS, Auteur Langues : Anglais (eng) Mots-clés : Adult  Brain/pathology  Chromosomes, Human, X  Female  Humans  Magnetic Resonance Imaging/methods  Sex Chromosome Aberrations  Sex Chromosome Disorders of Sex Development/pathology  Trisomy  47,xxx  7t  Adults  Cortical folding  Cortical surface area  Cortical thickness  Social cognition  Social functioning  Subcortical volume Index. décimale : PER Périodiques Résumé : BACKGROUND: Triple X syndrome (47,XXX) is a relatively common sex chromosomal aneuploidy characterized by the presence of a supernumerary X chromosome in females and has been associated with a variable cognitive, behavioural and psychiatric phenotype. 47,XXX may serve as a suitable model for studying the effect of genetic architecture on brain morphology. Previous studies have shown alterations in brain structure in 47,XXX particularly in childhood and adolescence. In this study, we examined subcortical and cortical brain morphology in adult women with 47,XXX using ultra-high field 7T MRI. Given previous evidence of impaired social functioning and emotion recognition in adults with 47,XXX, we also investigated the relationship of these functions with brain morphology. METHODS: Twenty-one adult women with 47,XXX and 22 age- and sex-matched healthy controls were included. Structural T1-weighted images were acquired using a 7-Tesla magnetic resonance scanner. Measures of subcortical brain volumes, cortical surface area and thickness, and cortical folding were obtained and compared between the groups using general linear models. Additionally, we examined potential relationships between brain outcome measures and social functioning and social cognition in 47,XXX using correlation analyses. RESULTS: Adults with 47,XXX showed lower volumes of the thalamus, caudate, putamen, hippocampus, nucleus accumbens and pallidum, and larger lateral ventricle volumes. Lower surface area was found in the superior frontal gyrus and superior temporal gyrus in 47,XXX participants compared to healthy controls. Altered cortical thickness and cortical folding were not present in 47,XXX. Cortical thickness was associated with social cognition in 47,XXX. CONCLUSIONS: Results suggest that a supernumerary X chromosome in females affects subcortical and lateral ventricle volumes, and cortical surface area in adulthood. 47,XXX may serve as a suitable model for studying genetic influences on structural brain morphology across developmental stages in order to understand neurobiological mechanisms underlying cognitive and behavioural impairments. En ligne : https://dx.doi.org/10.1186/s11689-022-09425-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=574 [article] Altered subcortical and cortical brain morphology in adult women with 47,XXX: a 7-Tesla magnetic resonance imaging study [texte imprimé] / Chaira SERRARENS, Auteur ; Maarten OTTER, Auteur ; Bea C.M. CAMPFORTS, Auteur ; Constance T.R.M. STUMPEL, Auteur ; Henk JANSMA, Auteur ; Therese A.M.J. VAN AMELSVOORT, Auteur ; Claudia VINGERHOETS, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 14 (2022) Mots-clés : Adult  Brain/pathology  Chromosomes, Human, X  Female  Humans  Magnetic Resonance Imaging/methods  Sex Chromosome Aberrations  Sex Chromosome Disorders of Sex Development/pathology  Trisomy  47,xxx  7t  Adults  Cortical folding  Cortical surface area  Cortical thickness  Social cognition  Social functioning  Subcortical volume Index. décimale : PER Périodiques Résumé : BACKGROUND: Triple X syndrome (47,XXX) is a relatively common sex chromosomal aneuploidy characterized by the presence of a supernumerary X chromosome in females and has been associated with a variable cognitive, behavioural and psychiatric phenotype. 47,XXX may serve as a suitable model for studying the effect of genetic architecture on brain morphology. Previous studies have shown alterations in brain structure in 47,XXX particularly in childhood and adolescence. In this study, we examined subcortical and cortical brain morphology in adult women with 47,XXX using ultra-high field 7T MRI. Given previous evidence of impaired social functioning and emotion recognition in adults with 47,XXX, we also investigated the relationship of these functions with brain morphology. METHODS: Twenty-one adult women with 47,XXX and 22 age- and sex-matched healthy controls were included. Structural T1-weighted images were acquired using a 7-Tesla magnetic resonance scanner. Measures of subcortical brain volumes, cortical surface area and thickness, and cortical folding were obtained and compared between the groups using general linear models. Additionally, we examined potential relationships between brain outcome measures and social functioning and social cognition in 47,XXX using correlation analyses. RESULTS: Adults with 47,XXX showed lower volumes of the thalamus, caudate, putamen, hippocampus, nucleus accumbens and pallidum, and larger lateral ventricle volumes. Lower surface area was found in the superior frontal gyrus and superior temporal gyrus in 47,XXX participants compared to healthy controls. Altered cortical thickness and cortical folding were not present in 47,XXX. Cortical thickness was associated with social cognition in 47,XXX. CONCLUSIONS: Results suggest that a supernumerary X chromosome in females affects subcortical and lateral ventricle volumes, and cortical surface area in adulthood. 47,XXX may serve as a suitable model for studying genetic influences on structural brain morphology across developmental stages in order to understand neurobiological mechanisms underlying cognitive and behavioural impairments. En ligne : https://dx.doi.org/10.1186/s11689-022-09425-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=574

Amniotic Fluid MMP-9 and Neurotrophins in Autism Spectrum Disorders: An Exploratory Study / Morsi W. ABDALLAH in Autism Research, 5-6 (December 2012)  

Public ISBD [article]  inAutism Research > 5-6 (December 2012) . - p.428-433 Titre : Amniotic Fluid MMP-9 and Neurotrophins in Autism Spectrum Disorders: An Exploratory Study Type de document : texte imprimé Auteurs : Morsi W. ABDALLAH, Auteur ; Brad D. PEARCE, Auteur ; Nanna LARSEN, Auteur ; Kirstin GREAVES-LORD, Auteur ; Bent NØRGAARD-PEDERSEN, Auteur ; David M. HOUGAARD, Auteur ; Erik Lykke MORTENSEN, Auteur ; Jakob GROVE, Auteur Article en page(s) : p.428-433 Mots-clés : neuronal plasticity  autistic disorder  amniotic fluid  matrix metalloproteinase  neurotrophins Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1254 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=187 [article] Amniotic Fluid MMP-9 and Neurotrophins in Autism Spectrum Disorders: An Exploratory Study [texte imprimé] / Morsi W. ABDALLAH, Auteur ; Brad D. PEARCE, Auteur ; Nanna LARSEN, Auteur ; Kirstin GREAVES-LORD, Auteur ; Bent NØRGAARD-PEDERSEN, Auteur ; David M. HOUGAARD, Auteur ; Erik Lykke MORTENSEN, Auteur ; Jakob GROVE, Auteur . - p.428-433. in Autism Research > 5-6 (December 2012) . - p.428-433 Mots-clés : neuronal plasticity  autistic disorder  amniotic fluid  matrix metalloproteinase  neurotrophins Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1254 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=187

Analysis of Fmr1 Deletion in a Subpopulation of Post-Mitotic Neurons in Mouse Cortex and Hippocampus / Anahita AMIRI in Autism Research, 7-1 (February 2014)  

Permalink

Annotation: Neurofeedback – train your brain to train behaviour / Hartmut HEINRICH in Journal of Child Psychology and Psychiatry, 48-1 (January 2007)  

Permalink

Annual Research Review: Progress in using brain morphometry as a clinical tool for diagnosing psychiatric disorders / Alexander HAUBOLD in Journal of Child Psychology and Psychiatry, 53-5 (May 2012)  

Permalink

Annual Research Review: Resilient functioning in maltreated children – past, present, and future perspectives / Dante CICCHETTI in Journal of Child Psychology and Psychiatry, 54-4 (April 2013)  

Permalink

Are Autistic Traits in the General Population Related to Global and Regional Brain Differences? / P. Cédric KOOLSCHIJN in Journal of Autism and Developmental Disorders, 45-9 (September 2015)  

Permalink