3 recherche sur le mot-clé 'N2'

Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism / Franc C L. DONKERS in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.506-523 Titre : Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism Type de document : texte imprimé Auteurs : Franc C L. DONKERS, Auteur ; Sarah E. SCHIPUL, Auteur ; Grace T. BARANEK, Auteur ; Katherine M. CLEARY, Auteur ; Michael T. WILLOUGHBY, Auteur ; Anna M. EVANS, Auteur ; John C. BULLUCK, Auteur ; Jeanne E. LOVMO, Auteur ; Aysenil BELGER, Auteur Article en page(s) : p.506-523 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sensory processing  Event-related potentials  P1  N2  P3a Index. décimale : PER Périodiques Résumé : Neurobiological underpinnings of unusual sensory features in individuals with autism are unknown. Event-related potentials elicited by task-irrelevant sounds were used to elucidate neural correlates of auditory processing and associations with three common sensory response patterns (hyperresponsiveness; hyporesponsiveness; sensory seeking). Twenty-eight children with autism and 39 typically developing children (4–12 year-olds) completed an auditory oddball paradigm. Results revealed marginally attenuated P1 and N2 to standard tones and attenuated P3a to novel sounds in autism versus controls. Exploratory analyses suggested that within the autism group, attenuated N2 and P3a amplitudes were associated with greater sensory seeking behaviors for specific ranges of P1 responses. Findings suggest that attenuated early sensory as well as later attention-orienting neural responses to stimuli may underlie selective sensory features via complex mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-013-1948-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism [texte imprimé] / Franc C L. DONKERS, Auteur ; Sarah E. SCHIPUL, Auteur ; Grace T. BARANEK, Auteur ; Katherine M. CLEARY, Auteur ; Michael T. WILLOUGHBY, Auteur ; Anna M. EVANS, Auteur ; John C. BULLUCK, Auteur ; Jeanne E. LOVMO, Auteur ; Aysenil BELGER, Auteur . - p.506-523. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.506-523 Mots-clés : Autism spectrum disorder  Sensory processing  Event-related potentials  P1  N2  P3a Index. décimale : PER Périodiques Résumé : Neurobiological underpinnings of unusual sensory features in individuals with autism are unknown. Event-related potentials elicited by task-irrelevant sounds were used to elucidate neural correlates of auditory processing and associations with three common sensory response patterns (hyperresponsiveness; hyporesponsiveness; sensory seeking). Twenty-eight children with autism and 39 typically developing children (4–12 year-olds) completed an auditory oddball paradigm. Results revealed marginally attenuated P1 and N2 to standard tones and attenuated P3a to novel sounds in autism versus controls. Exploratory analyses suggested that within the autism group, attenuated N2 and P3a amplitudes were associated with greater sensory seeking behaviors for specific ranges of P1 responses. Findings suggest that attenuated early sensory as well as later attention-orienting neural responses to stimuli may underlie selective sensory features via complex mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-013-1948-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Cognitive control and conflict adaptation in youth with high-functioning autism / Michael J. LARSON in Journal of Child Psychology and Psychiatry, 53-4 (April 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-4 (April 2012) . - p.440-448 Titre : Cognitive control and conflict adaptation in youth with high-functioning autism Type de document : texte imprimé Auteurs : Michael J. LARSON, Auteur ; Mikle SOUTH, Auteur ; Peter E. CLAYSON, Auteur ; Ann CLAWSON, Auteur Année de publication : 2012 Article en page(s) : p.440-448 Langues : Anglais (eng) Mots-clés : N2  event-related potential  autism  conflict adaptation  cognitive control Index. décimale : PER Périodiques Résumé : Background:  Youth diagnosed with autism spectrum disorders (ASD) often show deficits in cognitive control processes, potentially contributing to characteristic difficulties monitoring and regulating behavior. Modification of performance following conflict can be measured by examining conflict adaptation, the adjustment of cognitive resources based on previous-trial conflict. The electrophysiological correlates of these processes can be measured using the N2, a stimulus-locked component of the event-related potential (ERP). Methods:  High-density ERPs and behavioral data [i.e. response times (RTs) and error rates] were acquired while 28 youth with ASD and 36 typically developing controls completed a modified Eriksen flanker task. Results:  Behaviorally, groups showed similar conflict adaptation effects; youth with ASD showed larger RT slowing on switch trials. For electrophysiology, controls demonstrated larger N2 amplitudes for incongruent (high-conflict) trials following congruent (low-conflict) trials than for incongruent trials following incongruent trials. Importantly, youth with ASD showed no such differences in N2 amplitude based on previous-trial conflict. Conclusions:  Lack of electrophysiological conflict adaptation effects in youth with ASD indicates irregular neural processing associated with conflict adaptation. Individuals with ASD show declines in level of conflict evaluation and adaptation. Future research is necessary to accurately characterize and understand the behavioral implications of these cognitive control deficits relative to diagnostic severity, anxiety, and personality. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02498.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152 [article] Cognitive control and conflict adaptation in youth with high-functioning autism [texte imprimé] / Michael J. LARSON, Auteur ; Mikle SOUTH, Auteur ; Peter E. CLAYSON, Auteur ; Ann CLAWSON, Auteur . - 2012 . - p.440-448. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-4 (April 2012) . - p.440-448 Mots-clés : N2  event-related potential  autism  conflict adaptation  cognitive control Index. décimale : PER Périodiques Résumé : Background:  Youth diagnosed with autism spectrum disorders (ASD) often show deficits in cognitive control processes, potentially contributing to characteristic difficulties monitoring and regulating behavior. Modification of performance following conflict can be measured by examining conflict adaptation, the adjustment of cognitive resources based on previous-trial conflict. The electrophysiological correlates of these processes can be measured using the N2, a stimulus-locked component of the event-related potential (ERP). Methods:  High-density ERPs and behavioral data [i.e. response times (RTs) and error rates] were acquired while 28 youth with ASD and 36 typically developing controls completed a modified Eriksen flanker task. Results:  Behaviorally, groups showed similar conflict adaptation effects; youth with ASD showed larger RT slowing on switch trials. For electrophysiology, controls demonstrated larger N2 amplitudes for incongruent (high-conflict) trials following congruent (low-conflict) trials than for incongruent trials following incongruent trials. Importantly, youth with ASD showed no such differences in N2 amplitude based on previous-trial conflict. Conclusions:  Lack of electrophysiological conflict adaptation effects in youth with ASD indicates irregular neural processing associated with conflict adaptation. Individuals with ASD show declines in level of conflict evaluation and adaptation. Future research is necessary to accurately characterize and understand the behavioral implications of these cognitive control deficits relative to diagnostic severity, anxiety, and personality. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02498.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152

Chronometrical analysis of event-related potentials and reaction time in patients with multiple lacunar infarcts / Hisao TACHIBANA in Cognitive Brain Research, 1-3 (October 1993)

Public ISBD [article]  inCognitive Brain Research > 1-3 (October 1993) . - p.193-196 Titre : Chronometrical analysis of event-related potentials and reaction time in patients with multiple lacunar infarcts Type de document : texte imprimé Auteurs : Hisao TACHIBANA, Auteur ; Kazuo TODA, Auteur ; Kazumi ARAGANE, Auteur ; Minoru SUGITA, Auteur Année de publication : 1993 Article en page(s) : p.193-196 Langues : Anglais (eng) Mots-clés : Event-related-potential P3 N2 Reaction-time Multiple-lacunar-infarct Cognition Index. décimale : PER Périodiques Résumé : We measured the visual event-related potentials (ERPs) and reaction time (RT) in 31 patients with multiple lacunar infarcts and 18 age-equivalent normal subjects. The N2 and RT latencies of the patients were significantly longer than those of normal subjects, although P2 and P3 latencies did not differ between the two groups. However, the time from N2 to RT did not differ between the two groups. These observations suggest that the impairment of cognitive information processing in these patients arises from an uncertainty in classifying the perceived event, while motor organization time is relatively well preserved. In addition, the N2 latency may be more sensitive in detecting cognitive impairment in such patients. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=781 [article] Chronometrical analysis of event-related potentials and reaction time in patients with multiple lacunar infarcts [texte imprimé] / Hisao TACHIBANA, Auteur ; Kazuo TODA, Auteur ; Kazumi ARAGANE, Auteur ; Minoru SUGITA, Auteur . - 1993 . - p.193-196. Langues : Anglais (eng) in Cognitive Brain Research > 1-3 (October 1993) . - p.193-196 Mots-clés : Event-related-potential P3 N2 Reaction-time Multiple-lacunar-infarct Cognition Index. décimale : PER Périodiques Résumé : We measured the visual event-related potentials (ERPs) and reaction time (RT) in 31 patients with multiple lacunar infarcts and 18 age-equivalent normal subjects. The N2 and RT latencies of the patients were significantly longer than those of normal subjects, although P2 and P3 latencies did not differ between the two groups. However, the time from N2 to RT did not differ between the two groups. These observations suggest that the impairment of cognitive information processing in these patients arises from an uncertainty in classifying the perceived event, while motor organization time is relatively well preserved. In addition, the N2 latency may be more sensitive in detecting cognitive impairment in such patients. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=781