Genetic and attachment influences on adolescents'regulation of autonomy and aggressiveness / Peter ZIMMERMANN in Journal of Child Psychology and Psychiatry, 50-11 (November 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-11 (November 2009) . - p.1339-1347 Titre : Genetic and attachment influences on adolescents'regulation of autonomy and aggressiveness Type de document : Texte imprimé et/ou numérique Auteurs : Peter ZIMMERMANN, Auteur ; Gottfried SPANGLER, Auteur ; Cornelia MOHR, Auteur Année de publication : 2009 Article en page(s) : p.1339-1347 Langues : Anglais (eng) Mots-clés : Serotonin-transporter emotion-regulation attachment autonomy adolescence Index. décimale : PER Périodiques Résumé : Background: Adolescence is a time when intense emotions are elicited within the parent–adolescent relationship, often when autonomy subjectively is endangered. As emotion dysregulation is one of the risk processes for the development of psychopathology, adolescence may be perceived as a highly sensitive period for maladjustment. Inter-individual differences in emotionality and emotion regulation have been shown to be influenced or moderated by molecular genetic differences in the serotonin transporter gene (5-HTT) and by attachment patterns. We investigated whether both the 5-HTT and attachment are associated with emotionality and emotion regulation in an observed adolescent–mother interaction and the personality traits aggressiveness and anxiety in adolescence. Methods: Ninety-one adolescents at age 12 were observed in interaction with their mothers during a standardized emotion-eliciting social task to assess emotionality and emotion regulation in relation to autonomy. Adolescents' aggressiveness and anxiety were assessed by mother report. Concurrent attachment quality was determined by an attachment interview. DNA samples were collected in order to assess the 5-HTTLPR, a repeat polymorphism in the promoter region of the serotonin transporter gene. Results: While the short allele of the serotonin transporter gene was associated with a higher overall rate of autonomy behaviors, attachment security was related to more agreeable and less hostile autonomy. A significant interaction revealed a moderating effect of attachment security. Carriers of the short version of the 5-HTTLPR showed more agreeable autonomy when they had a secure attachment behavior strategy but showed more hostile autonomy when they were insecurely attached. Carriers of the short version of the 5-HTTLPR and insecurely attached adolescents were rated as more aggressive. Conclusions: The study suggests a gene–attachment interaction in adolescents where the adolescent's attachment status moderates a genetically based higher negative reactivity in response to threats to autonomy in social interactions. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02158.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=848 [article] Genetic and attachment influences on adolescents'regulation of autonomy and aggressiveness [Texte imprimé et/ou numérique] / Peter ZIMMERMANN, Auteur ; Gottfried SPANGLER, Auteur ; Cornelia MOHR, Auteur . - 2009 . - p.1339-1347. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-11 (November 2009) . - p.1339-1347 Mots-clés : Serotonin-transporter emotion-regulation attachment autonomy adolescence Index. décimale : PER Périodiques Résumé : Background: Adolescence is a time when intense emotions are elicited within the parent–adolescent relationship, often when autonomy subjectively is endangered. As emotion dysregulation is one of the risk processes for the development of psychopathology, adolescence may be perceived as a highly sensitive period for maladjustment. Inter-individual differences in emotionality and emotion regulation have been shown to be influenced or moderated by molecular genetic differences in the serotonin transporter gene (5-HTT) and by attachment patterns. We investigated whether both the 5-HTT and attachment are associated with emotionality and emotion regulation in an observed adolescent–mother interaction and the personality traits aggressiveness and anxiety in adolescence. Methods: Ninety-one adolescents at age 12 were observed in interaction with their mothers during a standardized emotion-eliciting social task to assess emotionality and emotion regulation in relation to autonomy. Adolescents' aggressiveness and anxiety were assessed by mother report. Concurrent attachment quality was determined by an attachment interview. DNA samples were collected in order to assess the 5-HTTLPR, a repeat polymorphism in the promoter region of the serotonin transporter gene. Results: While the short allele of the serotonin transporter gene was associated with a higher overall rate of autonomy behaviors, attachment security was related to more agreeable and less hostile autonomy. A significant interaction revealed a moderating effect of attachment security. Carriers of the short version of the 5-HTTLPR showed more agreeable autonomy when they had a secure attachment behavior strategy but showed more hostile autonomy when they were insecurely attached. Carriers of the short version of the 5-HTTLPR and insecurely attached adolescents were rated as more aggressive. Conclusions: The study suggests a gene–attachment interaction in adolescents where the adolescent's attachment status moderates a genetically based higher negative reactivity in response to threats to autonomy in social interactions. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02158.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=848

Genetic and environmental influence on attachment disorganization / Gottfried SPANGLER in Journal of Child Psychology and Psychiatry, 50-8 (August 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-8 (August 2009) . - p.952-961 Titre : Genetic and environmental influence on attachment disorganization Type de document : Texte imprimé et/ou numérique Auteurs : Gottfried SPANGLER, Auteur ; Monika JOHANN, Auteur ; Zsolt RONAI, Auteur ; Peter ZIMMERMANN, Auteur Année de publication : 2009 Article en page(s) : p.952-961 Langues : Anglais (eng) Mots-clés : Attachment gene–environment-interaction DRD4 serotonin-transporter Index. décimale : PER Périodiques Résumé : Background: Empirical studies demonstrate that maternal sensitivity is associated with attachment security in infancy, while maternal frightening/frightened behavior is related to attachment disorganization. However, attachment disorganization is also predicted by individual dispositions in infancy. Indeed, recent studies indicate a link between attachment disorganization and DRD4 gene polymorphisms, thus suggesting a genetic vulnerability for attachment disorganization. The aims of our study were twofold, to test a) a possible direct link between molecular genetic variations and attachment disorganization, and b) a possible gene–environment interaction with a moderating effect of early maternal caregiving. Methods: Attachment security and disorganization, as well as quality of maternal behavior were assessed in the infants of the Regensburg Longitudinal Study IV (N = 106) at the age of 12 months. DNA samples were collected in order to assess the exon III repeat polymorphism in the coding region and the −521 C/T single nucleotide polymorphism (SNP) in the regulatory region of the DRD4 gene and a repeat polymorphism (5-HTTLPR) in the promoter region of the serotonin transporter gene. Results: Significant associations were found between attachment disorganization and the short polymorphism of the serotonin transporter gene. Also, a gene–environment interaction indicated that this genetic association was only valid for infants of mothers exhibiting low responsiveness. No other significant genetic associations with attachment disorganization were apparent. Conclusions: The study suggests a gene–environment interaction whereby biological determinants of attachment disorganization are moderated by social experiences. Different pathways of the development of attachment disorganization are discussed based on a bio-behavioral model of development. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02054.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=787 [article] Genetic and environmental influence on attachment disorganization [Texte imprimé et/ou numérique] / Gottfried SPANGLER, Auteur ; Monika JOHANN, Auteur ; Zsolt RONAI, Auteur ; Peter ZIMMERMANN, Auteur . - 2009 . - p.952-961. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-8 (August 2009) . - p.952-961 Mots-clés : Attachment gene–environment-interaction DRD4 serotonin-transporter Index. décimale : PER Périodiques Résumé : Background: Empirical studies demonstrate that maternal sensitivity is associated with attachment security in infancy, while maternal frightening/frightened behavior is related to attachment disorganization. However, attachment disorganization is also predicted by individual dispositions in infancy. Indeed, recent studies indicate a link between attachment disorganization and DRD4 gene polymorphisms, thus suggesting a genetic vulnerability for attachment disorganization. The aims of our study were twofold, to test a) a possible direct link between molecular genetic variations and attachment disorganization, and b) a possible gene–environment interaction with a moderating effect of early maternal caregiving. Methods: Attachment security and disorganization, as well as quality of maternal behavior were assessed in the infants of the Regensburg Longitudinal Study IV (N = 106) at the age of 12 months. DNA samples were collected in order to assess the exon III repeat polymorphism in the coding region and the −521 C/T single nucleotide polymorphism (SNP) in the regulatory region of the DRD4 gene and a repeat polymorphism (5-HTTLPR) in the promoter region of the serotonin transporter gene. Results: Significant associations were found between attachment disorganization and the short polymorphism of the serotonin transporter gene. Also, a gene–environment interaction indicated that this genetic association was only valid for infants of mothers exhibiting low responsiveness. No other significant genetic associations with attachment disorganization were apparent. Conclusions: The study suggests a gene–environment interaction whereby biological determinants of attachment disorganization are moderated by social experiences. Different pathways of the development of attachment disorganization are discussed based on a bio-behavioral model of development. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02054.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=787

---

1 (1 - 2 / 2)