Categorical and Dimensional Structure of Autism Spectrum Disorders: The Nosologic Validity of Asperger Syndrome / Inge KAMP-BECKER in Journal of Autism and Developmental Disorders, 40-8 (August 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-8 (August 2010) . - p.921-929 Titre : Categorical and Dimensional Structure of Autism Spectrum Disorders: The Nosologic Validity of Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Inge KAMP-BECKER, Auteur ; Katja BECKER, Auteur ; Helmut REMSCHMIDT, Auteur ; Mardjan GHAHREMAN, Auteur ; Judith SMIDT, Auteur ; Monika HEINZEL-GUTENBRUNNER, Auteur Année de publication : 2010 Article en page(s) : p.921-929 Langues : Anglais (eng) Mots-clés : Dimensional Categorical Diagnosis Asperger-syndrome Autism-spectrum-disorders Index. décimale : PER Périodiques Résumé : There is an ongoing debate whether a differentiation of autistic subtypes, especially between Asperger Syndrome (AS) and high-functioning-autism (HFA) is possible and if so, whether it is a categorical or dimensional one. The aim of this study was to examine the possible clustering of responses in different symptom domains without making any assumption concerning diagnostic appreciation. About 140 children and adolescents, incorporating 52 with a diagnosis of AS, 44 with HFA, 8 with atypical autism and 36 with other diagnoses, were examined. Our study does not support the thesis that autistic disorders are discrete phenotypes. On the contrary, it provides evidence that e.g. AS and autism are not qualitatively distinct disorders, but rather different quantitative manifestations of the same disorder. En ligne : http://dx.doi.org/10.1007/s10803-010-0939-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108 [article] Categorical and Dimensional Structure of Autism Spectrum Disorders: The Nosologic Validity of Asperger Syndrome [Texte imprimé et/ou numérique] / Inge KAMP-BECKER, Auteur ; Katja BECKER, Auteur ; Helmut REMSCHMIDT, Auteur ; Mardjan GHAHREMAN, Auteur ; Judith SMIDT, Auteur ; Monika HEINZEL-GUTENBRUNNER, Auteur . - 2010 . - p.921-929. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-8 (August 2010) . - p.921-929 Mots-clés : Dimensional Categorical Diagnosis Asperger-syndrome Autism-spectrum-disorders Index. décimale : PER Périodiques Résumé : There is an ongoing debate whether a differentiation of autistic subtypes, especially between Asperger Syndrome (AS) and high-functioning-autism (HFA) is possible and if so, whether it is a categorical or dimensional one. The aim of this study was to examine the possible clustering of responses in different symptom domains without making any assumption concerning diagnostic appreciation. About 140 children and adolescents, incorporating 52 with a diagnosis of AS, 44 with HFA, 8 with atypical autism and 36 with other diagnoses, were examined. Our study does not support the thesis that autistic disorders are discrete phenotypes. On the contrary, it provides evidence that e.g. AS and autism are not qualitatively distinct disorders, but rather different quantitative manifestations of the same disorder. En ligne : http://dx.doi.org/10.1007/s10803-010-0939-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108

Diagnostic utility of the autism diagnostic observation schedule in a clinical sample of adolescents and adults / Anika LANGMANN in Research in Autism Spectrum Disorders, 34 (February 2017)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 34 (February 2017) . - p.34-43 Titre : Diagnostic utility of the autism diagnostic observation schedule in a clinical sample of adolescents and adults Type de document : Texte imprimé et/ou numérique Auteurs : Anika LANGMANN, Auteur ; Joachim BECKER, Auteur ; Luise POUSTKA, Auteur ; Katja BECKER, Auteur ; Inge KAMP-BECKER, Auteur Article en page(s) : p.34-43 Langues : Anglais (eng) Mots-clés : Diagnosis of autism spectrum disorder  Autism in adults  Autism in women  ADOS  Sensitivity  Specificity Index. décimale : PER Périodiques Résumé : AbstractBackground The Autism Diagnostic Observation Schedule (ADOS) Module 4 was investigated in an independent clinical sample of highfunctioning adolescent and adult males and females with suspected autism spectrum disorder. Special attention was paid to the performance of the ADOS in the subgroups autism spectrum disorders (ASD), personality disorders and disorders with onset usually occurring in childhood and adolescence. Method The recently revised algorithm and severity scores for Module 4 were used to analyze predictive values compared to the original algorithm in a sample of N = 356, 21% females, age range 12–68 yrs. Results Both algorithms have good sensitivity and specificity, with slightly better results for the revised algorithm. Diagnostic accuracy is lower for females, older individuals, and individuals with personality disorders or higher intellectual abilities. Conclusion The revised algorithm has good utility when used as part of a comprehensive assessment procedure conducted by an experienced examiner and including information on developmental history. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.11.012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 [article] Diagnostic utility of the autism diagnostic observation schedule in a clinical sample of adolescents and adults [Texte imprimé et/ou numérique] / Anika LANGMANN, Auteur ; Joachim BECKER, Auteur ; Luise POUSTKA, Auteur ; Katja BECKER, Auteur ; Inge KAMP-BECKER, Auteur . - p.34-43. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 34 (February 2017) . - p.34-43 Mots-clés : Diagnosis of autism spectrum disorder  Autism in adults  Autism in women  ADOS  Sensitivity  Specificity Index. décimale : PER Périodiques Résumé : AbstractBackground The Autism Diagnostic Observation Schedule (ADOS) Module 4 was investigated in an independent clinical sample of highfunctioning adolescent and adult males and females with suspected autism spectrum disorder. Special attention was paid to the performance of the ADOS in the subgroups autism spectrum disorders (ASD), personality disorders and disorders with onset usually occurring in childhood and adolescence. Method The recently revised algorithm and severity scores for Module 4 were used to analyze predictive values compared to the original algorithm in a sample of N = 356, 21% females, age range 12–68 yrs. Results Both algorithms have good sensitivity and specificity, with slightly better results for the revised algorithm. Diagnostic accuracy is lower for females, older individuals, and individuals with personality disorders or higher intellectual abilities. Conclusion The revised algorithm has good utility when used as part of a comprehensive assessment procedure conducted by an experienced examiner and including information on developmental history. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.11.012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298

Do different ADHD-related etiological risks involve specific neuropsychological pathways? An analysis of mediation processes by inhibitory control and delay aversion / Ursula PAULI-POTT in Journal of Child Psychology and Psychiatry, 54-7 (July 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.800-809 Titre : Do different ADHD-related etiological risks involve specific neuropsychological pathways? An analysis of mediation processes by inhibitory control and delay aversion Type de document : Texte imprimé et/ou numérique Auteurs : Ursula PAULI-POTT, Auteur ; Silke DALIR, Auteur ; Tanja MINGEBACH, Auteur ; Alisa ROLLER, Auteur ; Katja BECKER, Auteur Article en page(s) : p.800-809 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Inhibitory control (IC) has been regarded as a neuropsychological basic deficit and as an endophenotype of attention deficit/hyperactivity disorder (ADHD). Implicated here are mediation processes between etiological factors and ADHD symptoms. We thus analyze whether and to what extent executive IC and delay aversion (DA; i.e., reward-related IC) performance mediate the associations of familial, prenatal, and psychosocial risks with ADHD symptoms. Methods The study sample consisted of 130 preschool children (3–6 years; 50% boys), including 20% (n = 26) with a positive family history of ADHD (familial risk). Prenatal risks were mainly taken from medical records. Psychosocial risks were assessed by a structured interview. ADHD symptoms were assessed by structured interviews and questionnaires completed by parents and teachers. A set of neuropsychological tasks on IC and DA was conducted with the children. Results Familial, prenatal, and psychosocial risks were significantly associated with ADHD symptoms. IC and DA also correlated significantly with ADHD symptoms. While the familial risk significantly correlated with IC and DA, psychosocial and prenatal risks were only weakly associated with these measures. The link between the familial risk and ADHD symptoms was partially mediated by IC and DA. Conclusions The results indicate different neuropsychological pathways related to ‘positive family history of ADHD’ and prenatal risks. Given a cross-validation in future studies, the results underscore the endophenotypic character of IC and DA in preschool ages. En ligne : http://dx.doi.org/10.1111/jcpp.12059 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203 [article] Do different ADHD-related etiological risks involve specific neuropsychological pathways? An analysis of mediation processes by inhibitory control and delay aversion [Texte imprimé et/ou numérique] / Ursula PAULI-POTT, Auteur ; Silke DALIR, Auteur ; Tanja MINGEBACH, Auteur ; Alisa ROLLER, Auteur ; Katja BECKER, Auteur . - p.800-809. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.800-809 Index. décimale : PER Périodiques Résumé : Background Inhibitory control (IC) has been regarded as a neuropsychological basic deficit and as an endophenotype of attention deficit/hyperactivity disorder (ADHD). Implicated here are mediation processes between etiological factors and ADHD symptoms. We thus analyze whether and to what extent executive IC and delay aversion (DA; i.e., reward-related IC) performance mediate the associations of familial, prenatal, and psychosocial risks with ADHD symptoms. Methods The study sample consisted of 130 preschool children (3–6 years; 50% boys), including 20% (n = 26) with a positive family history of ADHD (familial risk). Prenatal risks were mainly taken from medical records. Psychosocial risks were assessed by a structured interview. ADHD symptoms were assessed by structured interviews and questionnaires completed by parents and teachers. A set of neuropsychological tasks on IC and DA was conducted with the children. Results Familial, prenatal, and psychosocial risks were significantly associated with ADHD symptoms. IC and DA also correlated significantly with ADHD symptoms. While the familial risk significantly correlated with IC and DA, psychosocial and prenatal risks were only weakly associated with these measures. The link between the familial risk and ADHD symptoms was partially mediated by IC and DA. Conclusions The results indicate different neuropsychological pathways related to ‘positive family history of ADHD’ and prenatal risks. Given a cross-validation in future studies, the results underscore the endophenotypic character of IC and DA in preschool ages. En ligne : http://dx.doi.org/10.1111/jcpp.12059 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203

Does intensive multimodal treatment for maternal ADHD improve the efficacy of parent training for children with ADHD? A randomized controlled multicenter trial / Thomas JANS in Journal of Child Psychology and Psychiatry, 56-12 (December 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-12 (December 2015) . - p.1298-1313 Titre : Does intensive multimodal treatment for maternal ADHD improve the efficacy of parent training for children with ADHD? A randomized controlled multicenter trial Type de document : Texte imprimé et/ou numérique Auteurs : Thomas JANS, Auteur ; Christian JACOB, Auteur ; Andreas WARNKE, Auteur ; Ulrike ZWANZGER, Auteur ; Silke GROß-LESCH, Auteur ; Swantje MATTHIES, Auteur ; Patricia BOREL, Auteur ; Klaus HENNIGHAUSEN, Auteur ; Barbara HAACK-DEES, Auteur ; Michael RÖSLER, Auteur ; Wolfgang RETZ, Auteur ; Alexander VON GONTARD, Auteur ; Susann HÄNIG, Auteur ; Esther SOBANSKI, Auteur ; Barbara ALM, Auteur ; Luise POUSTKA, Auteur ; Sarah HOHMANN, Auteur ; Michael COLLA, Auteur ; Laura GENTSCHOW, Auteur ; Charlotte JAITE, Auteur ; Viola KAPPEL, Auteur ; Katja BECKER, Auteur ; Martin HOLTMANN, Auteur ; Christine FREITAG, Auteur ; Erika GRAF, Auteur ; Gabriele IHORST, Auteur ; Alexandra PHILIPSEN, Auteur Article en page(s) : p.1298-1313 Langues : Anglais (eng) Mots-clés : Parental ADHD  parent training  dialectical behavioral therapy  stimulant medication Index. décimale : PER Périodiques Résumé : Background This is the first randomized controlled multicenter trial to evaluate the effect of two treatments of maternal attention-deficit hyperactivity disorder (ADHD) on response to parent–child training targeting children's external psychopathology. Methods Mother–child dyads (n = 144; ADHD according to DSM-IV; children: 73.5% males, mean age 9.4 years) from five specialized university outpatient units in Germany were centrally randomized to multimodal maternal ADHD treatment [group psychotherapy plus open methylphenidate medication; treatment group (TG): n = 77] or to clinical management [supportive counseling without psychotherapy or psychopharmacotherapy; control group (CG): n = 67]. After 12 weeks, the maternal ADHD treatment was supplemented by individual parent–child training for all dyads. The primary outcome was a change in the children's externalizing symptom scores (investigator blinded to the treatment assignment) from baseline to the end of the parent–child training 6 months later. Maintenance therapy continued for another 6 months. An intention-to-treat analysis was performed within a linear regression model, controlling for baseline and center after multiple imputations of missing values. Results Exactly, 206 dyads were assessed for eligibility, 144 were randomized, and 143 were analyzed (TG: n = 77; CG: n = 66). After 6 months, no significant between-group differences were found in change scores for children's externalizing symptoms (adjusted mean TG-mean CG=1.1, 95% confidence interval ?0.5–2.7; p = .1854), although maternal psychopathology improved more in the TG. Children's externalizing symptom scores improved from a mean of 14.8 at baseline to 11.4 (TG) and 10.3 (CG) after 6 months and to 10.8 (TG) and 10.1 (CG) after 1 year. No severe harms related to study treatments were found, but adverse events were more frequent in TG mothers than in CG mothers. Conclusions The response in children's externalizing psychopathology did not differ between maternal treatment groups. However, multimodal treatment was associated with more improvement in maternal ADHD. Child and maternal treatment gains were stable (CCT-ISRCTN73911400). En ligne : http://dx.doi.org/10.1111/jcpp.12443 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273 [article] Does intensive multimodal treatment for maternal ADHD improve the efficacy of parent training for children with ADHD? A randomized controlled multicenter trial [Texte imprimé et/ou numérique] / Thomas JANS, Auteur ; Christian JACOB, Auteur ; Andreas WARNKE, Auteur ; Ulrike ZWANZGER, Auteur ; Silke GROß-LESCH, Auteur ; Swantje MATTHIES, Auteur ; Patricia BOREL, Auteur ; Klaus HENNIGHAUSEN, Auteur ; Barbara HAACK-DEES, Auteur ; Michael RÖSLER, Auteur ; Wolfgang RETZ, Auteur ; Alexander VON GONTARD, Auteur ; Susann HÄNIG, Auteur ; Esther SOBANSKI, Auteur ; Barbara ALM, Auteur ; Luise POUSTKA, Auteur ; Sarah HOHMANN, Auteur ; Michael COLLA, Auteur ; Laura GENTSCHOW, Auteur ; Charlotte JAITE, Auteur ; Viola KAPPEL, Auteur ; Katja BECKER, Auteur ; Martin HOLTMANN, Auteur ; Christine FREITAG, Auteur ; Erika GRAF, Auteur ; Gabriele IHORST, Auteur ; Alexandra PHILIPSEN, Auteur . - p.1298-1313. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-12 (December 2015) . - p.1298-1313 Mots-clés : Parental ADHD  parent training  dialectical behavioral therapy  stimulant medication Index. décimale : PER Périodiques Résumé : Background This is the first randomized controlled multicenter trial to evaluate the effect of two treatments of maternal attention-deficit hyperactivity disorder (ADHD) on response to parent–child training targeting children's external psychopathology. Methods Mother–child dyads (n = 144; ADHD according to DSM-IV; children: 73.5% males, mean age 9.4 years) from five specialized university outpatient units in Germany were centrally randomized to multimodal maternal ADHD treatment [group psychotherapy plus open methylphenidate medication; treatment group (TG): n = 77] or to clinical management [supportive counseling without psychotherapy or psychopharmacotherapy; control group (CG): n = 67]. After 12 weeks, the maternal ADHD treatment was supplemented by individual parent–child training for all dyads. The primary outcome was a change in the children's externalizing symptom scores (investigator blinded to the treatment assignment) from baseline to the end of the parent–child training 6 months later. Maintenance therapy continued for another 6 months. An intention-to-treat analysis was performed within a linear regression model, controlling for baseline and center after multiple imputations of missing values. Results Exactly, 206 dyads were assessed for eligibility, 144 were randomized, and 143 were analyzed (TG: n = 77; CG: n = 66). After 6 months, no significant between-group differences were found in change scores for children's externalizing symptoms (adjusted mean TG-mean CG=1.1, 95% confidence interval ?0.5–2.7; p = .1854), although maternal psychopathology improved more in the TG. Children's externalizing symptom scores improved from a mean of 14.8 at baseline to 11.4 (TG) and 10.3 (CG) after 6 months and to 10.8 (TG) and 10.1 (CG) after 1 year. No severe harms related to study treatments were found, but adverse events were more frequent in TG mothers than in CG mothers. Conclusions The response in children's externalizing psychopathology did not differ between maternal treatment groups. However, multimodal treatment was associated with more improvement in maternal ADHD. Child and maternal treatment gains were stable (CCT-ISRCTN73911400). En ligne : http://dx.doi.org/10.1111/jcpp.12443 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273

Effectiveness of the Stepping Stones Triple P group parenting program in reducing comorbid behavioral problems in children with autism / Daria KASPERZACK in Autism, 24-2 (February 2020)  

Public ISBD [article]  inAutism > 24-2 (February 2020) . - p.423-436 Titre : Effectiveness of the Stepping Stones Triple P group parenting program in reducing comorbid behavioral problems in children with autism Type de document : Texte imprimé et/ou numérique Auteurs : Daria KASPERZACK, Auteur ; Bastian SCHROTT, Auteur ; Tanja MINGEBACH, Auteur ; Katja BECKER, Auteur ; Roland BURGHARDT, Auteur ; Inge KAMP-BECKER, Auteur Article en page(s) : p.423-436 Langues : Anglais (eng) Mots-clés : Stepping Stones Triple P  autism spectrum disorders  behavioral problems  interventions-psychosocial/behavioral  parent training  psychiatric comorbidity Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders often exhibit comorbid behavioral problems. These problems have an impact on the severity of the core symptoms, the progression of the disorder as well as on the families' quality of life. We evaluated the effectiveness of the Stepping Stones Triple P group parent training program as a supplementary intervention in the treatment of children with autism spectrum disorder. Therefore, we employed a single group repeated measures design and assessed child variables via parents' and teachers' judgments at four successive time points. The participants were parents of 24 children with autism spectrum disorder aged between 3.6 and 12 years. We found a significant reduction of comorbid behavioral problems in the children, primarily in the parents' judgment at follow-up. Furthermore, a reduction of the autism spectrum disorder core symptoms emerged. The teachers' judgment particularly revealed an improvement in children's social relationships. Effect sizes were large (n(2) ranging from 0.14 to 0.23). The findings demonstrate the effectiveness of the Stepping Stones Triple P as a supplementary intervention for reducing comorbid behavioral problems in the treatment of children with autism spectrum disorder. Higher parental self-efficacy and parental attributions, including parents' ability to influence child problem behaviors, are discussed as important factors for the effectiveness of Stepping Stones Triple P. En ligne : http://dx.doi.org/10.1177/1362361319866063 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415 [article] Effectiveness of the Stepping Stones Triple P group parenting program in reducing comorbid behavioral problems in children with autism [Texte imprimé et/ou numérique] / Daria KASPERZACK, Auteur ; Bastian SCHROTT, Auteur ; Tanja MINGEBACH, Auteur ; Katja BECKER, Auteur ; Roland BURGHARDT, Auteur ; Inge KAMP-BECKER, Auteur . - p.423-436. Langues : Anglais (eng) in Autism > 24-2 (February 2020) . - p.423-436 Mots-clés : Stepping Stones Triple P  autism spectrum disorders  behavioral problems  interventions-psychosocial/behavioral  parent training  psychiatric comorbidity Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders often exhibit comorbid behavioral problems. These problems have an impact on the severity of the core symptoms, the progression of the disorder as well as on the families' quality of life. We evaluated the effectiveness of the Stepping Stones Triple P group parent training program as a supplementary intervention in the treatment of children with autism spectrum disorder. Therefore, we employed a single group repeated measures design and assessed child variables via parents' and teachers' judgments at four successive time points. The participants were parents of 24 children with autism spectrum disorder aged between 3.6 and 12 years. We found a significant reduction of comorbid behavioral problems in the children, primarily in the parents' judgment at follow-up. Furthermore, a reduction of the autism spectrum disorder core symptoms emerged. The teachers' judgment particularly revealed an improvement in children's social relationships. Effect sizes were large (n(2) ranging from 0.14 to 0.23). The findings demonstrate the effectiveness of the Stepping Stones Triple P as a supplementary intervention for reducing comorbid behavioral problems in the treatment of children with autism spectrum disorder. Higher parental self-efficacy and parental attributions, including parents' ability to influence child problem behaviors, are discussed as important factors for the effectiveness of Stepping Stones Triple P. En ligne : http://dx.doi.org/10.1177/1362361319866063 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415

Evaluation of the revised algorithm of Autism Diagnostic Observation Schedule (ADOS) in the diagnostic investigation of high-functioning children and adolescents with autism spectrum disorders / Inge KAMP-BECKER in Autism, 17-1 (January 2013)  

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Inhibitory control and delay aversion in unaffected preschoolers with a positive family history of attention deficit hyperactivity disorder / Ursula PAULI-POTT in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

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Visual exploratory behaviour in infancy and novelty seeking in adolescence: two developmentally specific phenotypes of DRD4? / Manfred LAUCHT in Journal of Child Psychology and Psychiatry, 47-11 (November 2006)  

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