Alterations in the inferior longitudinal fasciculus in autism and associations with visual processing: a diffusion-weighted MRI study / Bart BOETS in Molecular Autism, 9 (2018)  

Public ISBD [article]  inMolecular Autism > 9 (2018) . - 10p. Titre : Alterations in the inferior longitudinal fasciculus in autism and associations with visual processing: a diffusion-weighted MRI study Type de document : texte imprimé Auteurs : Bart BOETS, Auteur ; Lien VAN EYLEN, Auteur ; Kevin SITEK, Auteur ; Pieter MOORS, Auteur ; Ilse NOENS, Auteur ; Jean STEYAERT, Auteur ; Stefan SUNAERT, Auteur ; Johan WAGEMANS, Auteur Article en page(s) : 10p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Diffusion-weighted imaging  Inferior longitudinal fasciculus  Structural connectivity  Visual processing Index. décimale : PER Périodiques Résumé : Background: One of the most reported neural features of autism spectrum disorder (ASD) is the alteration of multiple long-range white matter fiber tracts, as assessed by diffusion-weighted imaging and indexed by reduced fractional anisotropy (FA). Recent methodological advances, however, have shown that this same pattern of reduced FA may be an artifact resulting from excessive head motion and poorer data quality and that aberrant structural connectivity in children with ASD is confined to the right inferior longitudinal fasciculus (ILF). This study aimed at replicating the observation of reduced FA along the right ILF in ASD, while controlling for group differences in head motion and data quality. In addition, we explored associations between reduced FA in the right ILF and quantitative ASD characteristics, and the involvement of the right ILF in visual processing, which is known to be altered in ASD. Method: Global probabilistic tractography was performed on diffusion-weighted imaging data of 17 adolescent boys with ASD and 17 typically developing boys, matched for age, performance IQ, handedness, and data quality. Four tasks were administered to measure various aspects of visual information processing, together with questionnaires assessing ASD characteristics. Group differences were examined and the neural data were integrated with previously published findings using Bayesian statistics to quantify evidence for replication and to pool data and thus increase statistical power. (Partial) correlations were calculated to investigate associations between measures. Results: The ASD group showed consistently reduced FA only in the right ILF and slower performance on the visual search task. Bayesian statistics pooling data across studies confirmed that group differences in FA were confined to the right ILF only, with the evidence for altered FA in the left ILF being indecisive. Lower FA in the right ILF tended to covary with slower visual search and a more fragmented part-oriented processing style. Individual differences in FA of the right ILF were not reliably associated with the severity of ASD traits after controlling for clinical status. Conclusion: Our findings support the growing evidence for reduced FA along a specific fiber tract in ASD, the right ILF. En ligne : http://dx.doi.org/10.1186/s13229-018-0188-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354 [article] Alterations in the inferior longitudinal fasciculus in autism and associations with visual processing: a diffusion-weighted MRI study [texte imprimé] / Bart BOETS, Auteur ; Lien VAN EYLEN, Auteur ; Kevin SITEK, Auteur ; Pieter MOORS, Auteur ; Ilse NOENS, Auteur ; Jean STEYAERT, Auteur ; Stefan SUNAERT, Auteur ; Johan WAGEMANS, Auteur . - 10p. Langues : Anglais (eng) in Molecular Autism > 9 (2018) . - 10p. Mots-clés : Autism spectrum disorder  Diffusion-weighted imaging  Inferior longitudinal fasciculus  Structural connectivity  Visual processing Index. décimale : PER Périodiques Résumé : Background: One of the most reported neural features of autism spectrum disorder (ASD) is the alteration of multiple long-range white matter fiber tracts, as assessed by diffusion-weighted imaging and indexed by reduced fractional anisotropy (FA). Recent methodological advances, however, have shown that this same pattern of reduced FA may be an artifact resulting from excessive head motion and poorer data quality and that aberrant structural connectivity in children with ASD is confined to the right inferior longitudinal fasciculus (ILF). This study aimed at replicating the observation of reduced FA along the right ILF in ASD, while controlling for group differences in head motion and data quality. In addition, we explored associations between reduced FA in the right ILF and quantitative ASD characteristics, and the involvement of the right ILF in visual processing, which is known to be altered in ASD. Method: Global probabilistic tractography was performed on diffusion-weighted imaging data of 17 adolescent boys with ASD and 17 typically developing boys, matched for age, performance IQ, handedness, and data quality. Four tasks were administered to measure various aspects of visual information processing, together with questionnaires assessing ASD characteristics. Group differences were examined and the neural data were integrated with previously published findings using Bayesian statistics to quantify evidence for replication and to pool data and thus increase statistical power. (Partial) correlations were calculated to investigate associations between measures. Results: The ASD group showed consistently reduced FA only in the right ILF and slower performance on the visual search task. Bayesian statistics pooling data across studies confirmed that group differences in FA were confined to the right ILF only, with the evidence for altered FA in the left ILF being indecisive. Lower FA in the right ILF tended to covary with slower visual search and a more fragmented part-oriented processing style. Individual differences in FA of the right ILF were not reliably associated with the severity of ASD traits after controlling for clinical status. Conclusion: Our findings support the growing evidence for reduced FA along a specific fiber tract in ASD, the right ILF. En ligne : http://dx.doi.org/10.1186/s13229-018-0188-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354

Atypical sensory processing in adolescents with an autism spectrum disorder and their non-affected siblings / Wouter DE LA MARCHE in Research in Autism Spectrum Disorders, 6-2 (April-June 2012)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 6-2 (April-June 2012) . - p.639-645 Titre : Atypical sensory processing in adolescents with an autism spectrum disorder and their non-affected siblings Type de document : texte imprimé Auteurs : Wouter DE LA MARCHE, Auteur ; Jean STEYAERT, Auteur ; Ilse NOENS, Auteur Année de publication : 2012 Article en page(s) : p.639-645 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Adolescents  Siblings  Sensory profile  Intermediate phenotype Index. décimale : PER Périodiques Résumé : Atypical sensory processing is common in autism spectrum disorders (ASD). Specific profiles have been proposed in different age groups, but no study has focused specifically on adolescents. Identifying traits of ASD that are shared by individuals with ASD and their non-affected family members can shed light on the genetic underpinnings of ASD. Eighty adolescents with ASD (64 boys, 16 girls), 56 non-affected adolescent siblings (21 boys, 35 girls) and 33 adolescent controls (18 boys, 15 girls) filled out the Adolescent/Adult Sensory Profile, a self-report questionnaire resulting in four sensory quadrants according to Dunn's model of sensory processing. Adolescents with ASD differed significantly from controls on the quadrants Sensation Seeking and Sensation Avoidance. On quadrant 2 (Sensation Seeking) siblings scored significantly lower than controls and significantly higher than ASD. These results confirm the presence of atypical sensory processing in adolescents with ASD. We argue that reduced Sensation Seeking might be a candidate for an intermediate phenotype. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.09.014 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150 [article] Atypical sensory processing in adolescents with an autism spectrum disorder and their non-affected siblings [texte imprimé] / Wouter DE LA MARCHE, Auteur ; Jean STEYAERT, Auteur ; Ilse NOENS, Auteur . - 2012 . - p.639-645. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 6-2 (April-June 2012) . - p.639-645 Mots-clés : Autism spectrum disorder  Adolescents  Siblings  Sensory profile  Intermediate phenotype Index. décimale : PER Périodiques Résumé : Atypical sensory processing is common in autism spectrum disorders (ASD). Specific profiles have been proposed in different age groups, but no study has focused specifically on adolescents. Identifying traits of ASD that are shared by individuals with ASD and their non-affected family members can shed light on the genetic underpinnings of ASD. Eighty adolescents with ASD (64 boys, 16 girls), 56 non-affected adolescent siblings (21 boys, 35 girls) and 33 adolescent controls (18 boys, 15 girls) filled out the Adolescent/Adult Sensory Profile, a self-report questionnaire resulting in four sensory quadrants according to Dunn's model of sensory processing. Adolescents with ASD differed significantly from controls on the quadrants Sensation Seeking and Sensation Avoidance. On quadrant 2 (Sensation Seeking) siblings scored significantly lower than controls and significantly higher than ASD. These results confirm the presence of atypical sensory processing in adolescents with ASD. We argue that reduced Sensation Seeking might be a candidate for an intermediate phenotype. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.09.014 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150

Behavioral effects of multiple-dose oxytocin treatment in autism: a randomized, placebo-controlled trial with long-term follow-up / Sylvie BERNAERTS in Molecular Autism, 11 (2020)  

Public ISBD [article]  inMolecular Autism > 11 (2020) . - 6 p. Titre : Behavioral effects of multiple-dose oxytocin treatment in autism: a randomized, placebo-controlled trial with long-term follow-up Type de document : texte imprimé Auteurs : Sylvie BERNAERTS, Auteur ; Bart BOETS, Auteur ; Guy BOSMANS, Auteur ; Jean STEYAERT, Auteur ; Kaat ALAERTS, Auteur Article en page(s) : 6 p. Langues : Anglais (eng) Mots-clés : Attachment  Autism spectrum disorder  Oxytocin  Repetitive and restricted behavior  Social responsiveness Index. décimale : PER Périodiques Résumé : BACKGROUND: Intranasal administration of the "prosocial" neuropeptide oxytocin is increasingly explored as a potential treatment for targeting the core characteristics of autism spectrum disorder (ASD). However, long-term follow-up studies, evaluating the possibility of long-lasting retention effects, are currently lacking. METHODS: Using a double-blind, randomized, placebo-controlled, parallel design, this pilot clinical trial explored the possibility of long-lasting behavioral effects of 4 weeks of intranasal oxytocin treatment (24 International Units once daily in the morning) in 40 adult men with ASD. To do so, self-report and informant-based questionnaires assessing core autism symptoms and characterizations of attachment were administered at baseline, immediately after 4 weeks of treatment (approximately 24 h after the last nasal spray administration), and at two follow-up sessions, 4 weeks and 1 year post-treatment. RESULTS: No treatment-specific effects were identified in the primary outcome assessing social symptoms (Social Responsiveness Scale, self- and informant-rated). In particular, with respect to self-reported social responsiveness, improvements were evident both in the oxytocin and in the placebo group, yielding no significant between-group difference (p = .37). Also informant-rated improvements in social responsiveness were not significantly larger in the oxytocin, compared to the placebo group (between-group difference: p = .19). Among the secondary outcome measures, treatment-specific improvements were identified in the Repetitive Behavior Scale and State Adult Attachment Measure, indicating reductions in self-reported repetitive behaviors (p = .04) and reduced feelings of avoidance toward others (p = .03) in the oxytocin group compared to the placebo group, up to 1 month and even 1 year post-treatment. Treatment-specific effects were also revealed in screenings of mood states (Profile of Mood States), indicating higher reports of "vigor" (feeling energetic, active, lively) in the oxytocin, compared to the placebo group (p = .03). CONCLUSIONS: While no treatment-specific improvements were evident in terms of core social symptoms, the current observations of long-term beneficial effects on repetitive behaviors and feelings of avoidance are promising and suggestive of a therapeutic potential of oxytocin treatment for ASD. However, given the exploratory nature of this pilot study, future studies are warranted to evaluate the long-term effects of OT administration further. TRIAL REGISTRATION: The trial was registered with the European Clinical Trial Registry (Eudract 2014-000586-45) on January 22, 2014 (https://www.clinicaltrialsregister.eu/ctr-search/trial/2014-000586-45/BE). En ligne : http://dx.doi.org/10.1186/s13229-020-0313-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427 [article] Behavioral effects of multiple-dose oxytocin treatment in autism: a randomized, placebo-controlled trial with long-term follow-up [texte imprimé] / Sylvie BERNAERTS, Auteur ; Bart BOETS, Auteur ; Guy BOSMANS, Auteur ; Jean STEYAERT, Auteur ; Kaat ALAERTS, Auteur . - 6 p. Langues : Anglais (eng) in Molecular Autism > 11 (2020) . - 6 p. Mots-clés : Attachment  Autism spectrum disorder  Oxytocin  Repetitive and restricted behavior  Social responsiveness Index. décimale : PER Périodiques Résumé : BACKGROUND: Intranasal administration of the "prosocial" neuropeptide oxytocin is increasingly explored as a potential treatment for targeting the core characteristics of autism spectrum disorder (ASD). However, long-term follow-up studies, evaluating the possibility of long-lasting retention effects, are currently lacking. METHODS: Using a double-blind, randomized, placebo-controlled, parallel design, this pilot clinical trial explored the possibility of long-lasting behavioral effects of 4 weeks of intranasal oxytocin treatment (24 International Units once daily in the morning) in 40 adult men with ASD. To do so, self-report and informant-based questionnaires assessing core autism symptoms and characterizations of attachment were administered at baseline, immediately after 4 weeks of treatment (approximately 24 h after the last nasal spray administration), and at two follow-up sessions, 4 weeks and 1 year post-treatment. RESULTS: No treatment-specific effects were identified in the primary outcome assessing social symptoms (Social Responsiveness Scale, self- and informant-rated). In particular, with respect to self-reported social responsiveness, improvements were evident both in the oxytocin and in the placebo group, yielding no significant between-group difference (p = .37). Also informant-rated improvements in social responsiveness were not significantly larger in the oxytocin, compared to the placebo group (between-group difference: p = .19). Among the secondary outcome measures, treatment-specific improvements were identified in the Repetitive Behavior Scale and State Adult Attachment Measure, indicating reductions in self-reported repetitive behaviors (p = .04) and reduced feelings of avoidance toward others (p = .03) in the oxytocin group compared to the placebo group, up to 1 month and even 1 year post-treatment. Treatment-specific effects were also revealed in screenings of mood states (Profile of Mood States), indicating higher reports of "vigor" (feeling energetic, active, lively) in the oxytocin, compared to the placebo group (p = .03). CONCLUSIONS: While no treatment-specific improvements were evident in terms of core social symptoms, the current observations of long-term beneficial effects on repetitive behaviors and feelings of avoidance are promising and suggestive of a therapeutic potential of oxytocin treatment for ASD. However, given the exploratory nature of this pilot study, future studies are warranted to evaluate the long-term effects of OT administration further. TRIAL REGISTRATION: The trial was registered with the European Clinical Trial Registry (Eudract 2014-000586-45) on January 22, 2014 (https://www.clinicaltrialsregister.eu/ctr-search/trial/2014-000586-45/BE). En ligne : http://dx.doi.org/10.1186/s13229-020-0313-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427

Brief Report: Reduced Grouping Interference in Children with ASD: Evidence from a Multiple Object Tracking Task / Kris EVERS in Journal of Autism and Developmental Disorders, 44-7 (July 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-7 (July 2014) . - p.1779-1787 Titre : Brief Report: Reduced Grouping Interference in Children with ASD: Evidence from a Multiple Object Tracking Task Type de document : texte imprimé Auteurs : Kris EVERS, Auteur ; Lee DE-WIT, Auteur ; Ruth VAN DER HALLEN, Auteur ; Birgitt HAESEN, Auteur ; Jean STEYAERT, Auteur ; Ilse NOENS, Auteur ; Johan WAGEMANS, Auteur Article en page(s) : p.1779-1787 Langues : Anglais (eng) Mots-clés : Attention  Autism spectrum disorder (ASD)  Global interference  Grouping  Multiple object tracking  Weak central coherence Index. décimale : PER Périodiques Résumé : This study was inspired by the more locally oriented processing style in autism spectrum disorders (ASD). A modified multiple object tracking (MOT) task was administered to a group of children with and without ASD. Participants not only had to distinguish moving targets from distracters, but they also had to track targets when they were visually grouped to distracters, a manipulation which has a detrimental effect on tracking performance in adults. MOT performance in the ASD group was also affected by grouping, but this effect was significantly reduced. This result highlights how the reduced bias towards more global processing in ASD could influence further stages of cognition by altering the way in which attention selects information for further processing. En ligne : http://dx.doi.org/10.1007/s10803-013-2031-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=236 [article] Brief Report: Reduced Grouping Interference in Children with ASD: Evidence from a Multiple Object Tracking Task [texte imprimé] / Kris EVERS, Auteur ; Lee DE-WIT, Auteur ; Ruth VAN DER HALLEN, Auteur ; Birgitt HAESEN, Auteur ; Jean STEYAERT, Auteur ; Ilse NOENS, Auteur ; Johan WAGEMANS, Auteur . - p.1779-1787. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-7 (July 2014) . - p.1779-1787 Mots-clés : Attention  Autism spectrum disorder (ASD)  Global interference  Grouping  Multiple object tracking  Weak central coherence Index. décimale : PER Périodiques Résumé : This study was inspired by the more locally oriented processing style in autism spectrum disorders (ASD). A modified multiple object tracking (MOT) task was administered to a group of children with and without ASD. Participants not only had to distinguish moving targets from distracters, but they also had to track targets when they were visually grouped to distracters, a manipulation which has a detrimental effect on tracking performance in adults. MOT performance in the ASD group was also affected by grouping, but this effect was significantly reduced. This result highlights how the reduced bias towards more global processing in ASD could influence further stages of cognition by altering the way in which attention selects information for further processing. En ligne : http://dx.doi.org/10.1007/s10803-013-2031-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=236

Can repeated intranasal oxytocin administration affect reduced neural sensitivity towards expressive faces in autism? A randomized controlled trial / Matthijs MOERKERKE in Journal of Child Psychology and Psychiatry, 64-11 (November 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1583-1595 Titre : Can repeated intranasal oxytocin administration affect reduced neural sensitivity towards expressive faces in autism? A randomized controlled trial Type de document : texte imprimé Auteurs : Matthijs MOERKERKE, Auteur ; Nicky DANIELS, Auteur ; Stephanie VAN DER DONCK, Auteur ; Laura TIBERMONT, Auteur ; Tiffany TANG, Auteur ; Edward DEBBAUT, Auteur ; Annelies BAMPS, Auteur ; Jellina PRINSEN, Auteur ; Jean STEYAERT, Auteur ; Kaat ALAERTS, Auteur ; Bart BOETS, Auteur Article en page(s) : p.1583-1595 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and interaction. Crucial for efficient social interaction is the ability to quickly and accurately extract information from a person's face. Frequency-tagging electroencephalography (EEG) is a novel tool to quantify face-processing sensitivity in a robust and implicit manner. In terms of intervention approaches, intranasal administration of oxytocin (OT) is increasingly considered as a potential pharmacological approach for improving socio-communicative difficulties in ASD, through enhancing social salience and/or reducing (social) stress and anxiety. Methods In this randomized, double-blind, placebo-controlled, mechanistic pharmaco-neuroimaging clinical trial, we implemented frequency-tagging EEG to conduct an exploratory investigation into the impact of repeated OT administration (4 weeks, 12 IU, twice daily) on neural sensitivity towards happy and fearful facial expressions in children with ASD (8-12 years old; OT: n=29; placebo: n=32). Neural effects were assessed at baseline, post-nasal spray (24 hr after the last nasal spray) and at a follow-up session, 4 weeks after the OT administration period. At baseline, neural assessments of children with ASD were compared with those of an age- and gender-matched cohort of neurotypical (NT) children (n=39). Results Children with ASD demonstrated reduced neural sensitivity towards expressive faces, as compared to NT children. Upon nasal spray administration, children with ASD displayed a significant increase in neural sensitivity at the post- and follow-up sessions, but only in the placebo group, likely reflecting an implicit learning effect. Strikingly, in the OT group, neural sensitivity remained unaffected from the baseline to the post-session, likely reflecting a dampening of an otherwise typically occurring implicit learning effect. Conclusions First, we validated the robustness of the frequency-tagging EEG approach to assess reduced neural sensitivity towards expressive faces in children with ASD. Furthermore, in contrast to social salience effects observed after single-dose administrations, repeated OT administration dampened typically occurring learning effects in neural sensitivity. In line with OT's social anxiolytic account, these observations possibly reflect a predominant (social) stress regulatory effect towards emotionally evocative faces after repeated OT administration. En ligne : https://doi.org/10.1111/jcpp.13850 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512 [article] Can repeated intranasal oxytocin administration affect reduced neural sensitivity towards expressive faces in autism? A randomized controlled trial [texte imprimé] / Matthijs MOERKERKE, Auteur ; Nicky DANIELS, Auteur ; Stephanie VAN DER DONCK, Auteur ; Laura TIBERMONT, Auteur ; Tiffany TANG, Auteur ; Edward DEBBAUT, Auteur ; Annelies BAMPS, Auteur ; Jellina PRINSEN, Auteur ; Jean STEYAERT, Auteur ; Kaat ALAERTS, Auteur ; Bart BOETS, Auteur . - p.1583-1595. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1583-1595 Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and interaction. Crucial for efficient social interaction is the ability to quickly and accurately extract information from a person's face. Frequency-tagging electroencephalography (EEG) is a novel tool to quantify face-processing sensitivity in a robust and implicit manner. In terms of intervention approaches, intranasal administration of oxytocin (OT) is increasingly considered as a potential pharmacological approach for improving socio-communicative difficulties in ASD, through enhancing social salience and/or reducing (social) stress and anxiety. Methods In this randomized, double-blind, placebo-controlled, mechanistic pharmaco-neuroimaging clinical trial, we implemented frequency-tagging EEG to conduct an exploratory investigation into the impact of repeated OT administration (4 weeks, 12 IU, twice daily) on neural sensitivity towards happy and fearful facial expressions in children with ASD (8-12 years old; OT: n=29; placebo: n=32). Neural effects were assessed at baseline, post-nasal spray (24 hr after the last nasal spray) and at a follow-up session, 4 weeks after the OT administration period. At baseline, neural assessments of children with ASD were compared with those of an age- and gender-matched cohort of neurotypical (NT) children (n=39). Results Children with ASD demonstrated reduced neural sensitivity towards expressive faces, as compared to NT children. Upon nasal spray administration, children with ASD displayed a significant increase in neural sensitivity at the post- and follow-up sessions, but only in the placebo group, likely reflecting an implicit learning effect. Strikingly, in the OT group, neural sensitivity remained unaffected from the baseline to the post-session, likely reflecting a dampening of an otherwise typically occurring implicit learning effect. Conclusions First, we validated the robustness of the frequency-tagging EEG approach to assess reduced neural sensitivity towards expressive faces in children with ASD. Furthermore, in contrast to social salience effects observed after single-dose administrations, repeated OT administration dampened typically occurring learning effects in neural sensitivity. In line with OT's social anxiolytic account, these observations possibly reflect a predominant (social) stress regulatory effect towards emotionally evocative faces after repeated OT administration. En ligne : https://doi.org/10.1111/jcpp.13850 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512

Change detection of meaningful objects in real-world scenes in adolescents with and without autism spectrum disorder / Steven VANMARCKE in Autism, 22-6 (August 2018)  

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Children with autism spectrum disorder spontaneously use scene knowledge to modulate visual object processing / Lien VAN EYLEN in Research in Autism Spectrum Disorders, 7-7 (July 2013)  

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Chronic oxytocin improves neural decoupling at rest in children with autism: an exploratory RCT / Matthijs MOERKERKE ; Nicky DANIELS ; Qianqian ZHANG ; Ricchiuti GRAZIA ; Jean STEYAERT ; Jellina PRINSEN ; Bart BOETS in Journal of Child Psychology and Psychiatry, 65-10 (October 2024)  

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Cognitive flexibility in autism spectrum disorder: Explaining the inconsistencies? / Lien VAN EYLEN in Research in Autism Spectrum Disorders, 5-4 (October-December 2011)  

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Combined frequency-tagging EEG and eye-tracking measures provide no support for the "excess mouth/diminished eye attention" hypothesis in autism / Sofie VETTORI in Molecular Autism, 11 (2020)  

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Combining strengths and weaknesses in visual perception of children with an autism spectrum disorder: Perceptual matching of facial expressions / Kris EVERS in Research in Autism Spectrum Disorders, 5-4 (October-December 2011)  

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Corrigendum to “Cognitive flexibility in autism spectrum disorder: Explaining the inconsistencies?” [Res. Autism Spectr. Disord. 5 (2011) 1390–1401] / Lien VAN EYLEN in Research in Autism Spectrum Disorders, 23 (March 2016)  

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Differences in cardiac vagal modulation and cortisol response in adolescents with and without Autism Spectrum Disorder / Anoushka THOEN in Research in Autism Spectrum Disorders, 104 (June 2023)  

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Disturbed Interplay Between Mid- and High-Level Vision in ASD? Evidence from a Contour Identification Task with Everyday Objects / Kris EVERS in Journal of Autism and Developmental Disorders, 44-4 (April 2014)  

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Do Parental Interviews for ASD Converge with Clinical Diagnoses? An Empirical Comparison of the 3di and the DISCO in Children with ASD, a Clinically-Referred Group, and Typically Developing Children / Kris EVERS in Journal of Autism and Developmental Disorders, 50-4 (April 2020)  

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