Dépouillements

Issue Information in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.917-919 Titre : Issue Information Type de document : Texte imprimé et/ou numérique Article en page(s) : p.917-919 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1554 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Issue Information [Texte imprimé et/ou numérique] . - p.917-919. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.917-919 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1554 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

Toward an interdisciplinary approach to understanding sensory function in autism spectrum disorder / Carissa J. CASCIO in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.920-925 Titre : Toward an interdisciplinary approach to understanding sensory function in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Carissa J. CASCIO, Auteur ; Tiffany G. WOYNAROSKI, Auteur ; Grace T. BARANEK, Auteur ; Mark T. WALLACE, Auteur Article en page(s) : p.920-925 Langues : Anglais (eng) Mots-clés : sensory processing  sensory integration  multisensory  autism  collaboration Index. décimale : PER Périodiques Résumé : Heightened interest in sensory function in persons with autism spectrum disorder (ASD) presents an unprecedented opportunity for impactful, interdisciplinary work between neuroscientists and clinical practitioners for whom sensory processing is a focus. In spite of this promise, and a number of overlapping perspectives on sensory function in persons with ASD, neuroscientists and clinical practitioners are faced with significant practical barriers to transcending disciplinary silos. These barriers include divergent goals, values, and approaches that shape each discipline, as well as different lexical conventions. This commentary is itself an interdisciplinary effort to describe the shared perspectives, and to conceptualize a framework that may guide future investigation in this area. We summarize progress to date and issue a call for clinical practitioners and neuroscientists to expand cross-disciplinary dialogue and to capitalize on the complementary strengths of each field to unveil the links between neural and behavioral manifestations of sensory differences in persons with ASD. Joining forces to face these challenges in a truly interdisciplinary way will lead to more clinically informed neuroscientific investigation of sensory function, and better translation of those findings to clinical practice. Likewise, a more coordinated effort may shed light not only on how current approaches to treating sensory processing differences affect brain and behavioral responses to sensory stimuli in individuals with ASD, but also on whether such approaches translate to gains in broader characteristics associated with ASD. It is our hope that such interdisciplinary undertakings will ultimately converge to improve assessment and interventions for persons with ASD. En ligne : http://dx.doi.org/10.1002/aur.1612 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Toward an interdisciplinary approach to understanding sensory function in autism spectrum disorder [Texte imprimé et/ou numérique] / Carissa J. CASCIO, Auteur ; Tiffany G. WOYNAROSKI, Auteur ; Grace T. BARANEK, Auteur ; Mark T. WALLACE, Auteur . - p.920-925. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.920-925 Mots-clés : sensory processing  sensory integration  multisensory  autism  collaboration Index. décimale : PER Périodiques Résumé : Heightened interest in sensory function in persons with autism spectrum disorder (ASD) presents an unprecedented opportunity for impactful, interdisciplinary work between neuroscientists and clinical practitioners for whom sensory processing is a focus. In spite of this promise, and a number of overlapping perspectives on sensory function in persons with ASD, neuroscientists and clinical practitioners are faced with significant practical barriers to transcending disciplinary silos. These barriers include divergent goals, values, and approaches that shape each discipline, as well as different lexical conventions. This commentary is itself an interdisciplinary effort to describe the shared perspectives, and to conceptualize a framework that may guide future investigation in this area. We summarize progress to date and issue a call for clinical practitioners and neuroscientists to expand cross-disciplinary dialogue and to capitalize on the complementary strengths of each field to unveil the links between neural and behavioral manifestations of sensory differences in persons with ASD. Joining forces to face these challenges in a truly interdisciplinary way will lead to more clinically informed neuroscientific investigation of sensory function, and better translation of those findings to clinical practice. Likewise, a more coordinated effort may shed light not only on how current approaches to treating sensory processing differences affect brain and behavioral responses to sensory stimuli in individuals with ASD, but also on whether such approaches translate to gains in broader characteristics associated with ASD. It is our hope that such interdisciplinary undertakings will ultimately converge to improve assessment and interventions for persons with ASD. En ligne : http://dx.doi.org/10.1002/aur.1612 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism / Yuta HARA in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.926-939 Titre : Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism Type de document : Texte imprimé et/ou numérique Auteurs : Yuta HARA, Auteur ; Yukio AGO, Auteur ; Atsuki TARUTA, Auteur ; Keisuke KATASHIBA, Auteur ; Shigeru HASEBE, Auteur ; Erika TAKANO, Auteur ; Yusuke ONAKA, Auteur ; Hitoshi HASHIMOTO, Auteur ; Toshio MATSUDA, Auteur ; Kazuhiro TAKUMA, Auteur Article en page(s) : p.926-939 Langues : Anglais (eng) Mots-clés : valproic acid  methylphenidate  atomoxetine  behavioral analysis  animal model Index. décimale : PER Périodiques Résumé : Rodents exposed prenatally to valproic acid (VPA) show autism-related behavioral abnormalities. We recently found that prenatal VPA exposure causes a reduction of dopaminergic activity in the prefrontal cortex of male, but not female, mice. This suggests that reduced prefrontal dopaminergic activity is associated with behavioral abnormalities in VPA-treated mice. In the present study, we examined whether the attention deficit/hyperactivity disorder drugs methylphenidate and atomoxetine (which increase dopamine release in the prefrontal cortex, but not striatum, in mice) could alleviate the behavioral abnormalities and changes in dendritic spine morphology induced by prenatal VPA exposure. We found that methylphenidate and atomoxetine increased prefrontal dopamine and noradrenaline release in VPA-treated mice. Acute treatment with methylphenidate or atomoxetine did not alleviate the social interaction deficits or recognition memory impairment in VPA-treated mice, while chronic treatment for 2 weeks did. Methylphenidate or atomoxetine for 2 weeks also improved the prenatal VPA-induced decrease in dendritic spine density in the prefrontal cortex. The effects of these drugs on behaviors and dendritic spine morphology were antagonized by concomitant treatment with the dopamine-D1 receptor antagonist SCH39166 or the dopamine-D2 receptor antagonist raclopride, but not by the ?2-adrenoceptor antagonist idazoxan. These findings suggest that chronic treatment with methylphenidate or atomoxetine improves abnormal behaviors and diminishes the reduction in spine density in VPA-treated mice via a prefrontal dopaminergic system-dependent mechanism. En ligne : http://dx.doi.org/10.1002/aur.1596 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism [Texte imprimé et/ou numérique] / Yuta HARA, Auteur ; Yukio AGO, Auteur ; Atsuki TARUTA, Auteur ; Keisuke KATASHIBA, Auteur ; Shigeru HASEBE, Auteur ; Erika TAKANO, Auteur ; Yusuke ONAKA, Auteur ; Hitoshi HASHIMOTO, Auteur ; Toshio MATSUDA, Auteur ; Kazuhiro TAKUMA, Auteur . - p.926-939. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.926-939 Mots-clés : valproic acid  methylphenidate  atomoxetine  behavioral analysis  animal model Index. décimale : PER Périodiques Résumé : Rodents exposed prenatally to valproic acid (VPA) show autism-related behavioral abnormalities. We recently found that prenatal VPA exposure causes a reduction of dopaminergic activity in the prefrontal cortex of male, but not female, mice. This suggests that reduced prefrontal dopaminergic activity is associated with behavioral abnormalities in VPA-treated mice. In the present study, we examined whether the attention deficit/hyperactivity disorder drugs methylphenidate and atomoxetine (which increase dopamine release in the prefrontal cortex, but not striatum, in mice) could alleviate the behavioral abnormalities and changes in dendritic spine morphology induced by prenatal VPA exposure. We found that methylphenidate and atomoxetine increased prefrontal dopamine and noradrenaline release in VPA-treated mice. Acute treatment with methylphenidate or atomoxetine did not alleviate the social interaction deficits or recognition memory impairment in VPA-treated mice, while chronic treatment for 2 weeks did. Methylphenidate or atomoxetine for 2 weeks also improved the prenatal VPA-induced decrease in dendritic spine density in the prefrontal cortex. The effects of these drugs on behaviors and dendritic spine morphology were antagonized by concomitant treatment with the dopamine-D1 receptor antagonist SCH39166 or the dopamine-D2 receptor antagonist raclopride, but not by the ?2-adrenoceptor antagonist idazoxan. These findings suggest that chronic treatment with methylphenidate or atomoxetine improves abnormal behaviors and diminishes the reduction in spine density in VPA-treated mice via a prefrontal dopaminergic system-dependent mechanism. En ligne : http://dx.doi.org/10.1002/aur.1596 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

Using the brief observation of social communication change (BOSCC) to measure autism-specific development / Janina KITZEROW in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.940-950 Titre : Using the brief observation of social communication change (BOSCC) to measure autism-specific development Type de document : Texte imprimé et/ou numérique Auteurs : Janina KITZEROW, Auteur ; Karoline TEUFEL, Auteur ; Christian WILKER, Auteur ; Christine M. FREITAG, Auteur Article en page(s) : p.940-950 Langues : Anglais (eng) Mots-clés : early intervention  BOSCC  FFIP  autism-specific outcome  change measurement Index. décimale : PER Périodiques Résumé : To date no reliable and objective, change sensitive instrument for autistic symptoms is available. The brief observation of social communication change (BOSCC) was specifically developed to measure change of core autistic symptoms, for example, for use as outcome measure in early intervention trials. This study investigated quality criteria of a preliminary research version of the BOSCC in N?=?21 children with autism spectrum disorder (ASD) who had participated for 1 year in the Frankfurt early intervention program (FFIP). BOSCC rating was done on play based ADOS video scenes. Inter-rater agreement on the BOSCC average total was very high. The BOSCC showed a significant decrease of autistic symptoms after 1 year with a medium effect size. Symptom specific improvements were captured by the social communication subscale and most single items. The BOSCC showed comparable change sensitivity to other autism specific instruments. Future studies should focus on the finalized BOSCC version, and replicate findings in a larger sample. Autism Res 2016, 9: 940–950. En ligne : http://dx.doi.org/10.1002/aur.1588 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Using the brief observation of social communication change (BOSCC) to measure autism-specific development [Texte imprimé et/ou numérique] / Janina KITZEROW, Auteur ; Karoline TEUFEL, Auteur ; Christian WILKER, Auteur ; Christine M. FREITAG, Auteur . - p.940-950. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.940-950 Mots-clés : early intervention  BOSCC  FFIP  autism-specific outcome  change measurement Index. décimale : PER Périodiques Résumé : To date no reliable and objective, change sensitive instrument for autistic symptoms is available. The brief observation of social communication change (BOSCC) was specifically developed to measure change of core autistic symptoms, for example, for use as outcome measure in early intervention trials. This study investigated quality criteria of a preliminary research version of the BOSCC in N?=?21 children with autism spectrum disorder (ASD) who had participated for 1 year in the Frankfurt early intervention program (FFIP). BOSCC rating was done on play based ADOS video scenes. Inter-rater agreement on the BOSCC average total was very high. The BOSCC showed a significant decrease of autistic symptoms after 1 year with a medium effect size. Symptom specific improvements were captured by the social communication subscale and most single items. The BOSCC showed comparable change sensitivity to other autism specific instruments. Future studies should focus on the finalized BOSCC version, and replicate findings in a larger sample. Autism Res 2016, 9: 940–950. En ligne : http://dx.doi.org/10.1002/aur.1588 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study / Zeyan LIEW in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.951-958 Titre : Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Zeyan LIEW, Auteur ; Beate RITZ, Auteur ; Jasveer VIRK, Auteur ; Jørn OLSEN, Auteur Article en page(s) : p.951-958 Langues : Anglais (eng) Mots-clés : acetaminophen  autism spectrum disorders  infantile autism  childhood behavior  prenatal exposure  pregnancy cohort Index. décimale : PER Périodiques Résumé : Acetaminophen (paracetamol) is the most commonly used pain and fever medication during pregnancy. Previously, a positive ecological correlation between acetaminophen use and autism spectrum disorders (ASD) has been reported but evidence from larger studies based on prospective data is lacking. We followed 64,322 children and mothers enrolled in the Danish National Birth Cohort (DNBC; 1996–2002) for average 12.7 years to investigate whether acetaminophen use in pregnancy is associated with increased risk of ASD in the offspring. Information on acetaminophen use was collected prospectively from three computer-assisted telephone interviews. We used records from the Danish hospital and psychiatric registries to identify diagnoses of ASD. At the end of follow up, 1,027 (1.6%) children were diagnosed with ASD, 345 (0.5%) with infantile autism. We found that 31% of ASD (26% of infantile autism) have also been diagnosed with hyperkinetic disorders. More than 50% women reported ever using acetaminophen in pregnancy. We used Cox proportional hazards model to estimate hazard ratio (HR) and 95% confident interval (CI). Prenatal use of acetaminophen was associated with an increased risk of ASD accompanied by hyperkinetic symptoms (HR?=?1.51 95% CI 1.19–1.92), but not with other ASD cases (HR?=?1.06 95% CI 0.92–1.24). Longer duration of use (i.e., use for >20 weeks in gestation) increased the risk of ASD or infantile autism with hyperkinetic symptoms almost twofold. Maternal use of acetaminophen in pregnancy was associated with ASD with hyperkinetic symptoms only, suggesting acetaminophen exposure early in fetal life may specifically impact this hyperactive behavioral phenotype. Autism Res 2016, 9: 951–958. En ligne : http://dx.doi.org/10.1002/aur.1591 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study [Texte imprimé et/ou numérique] / Zeyan LIEW, Auteur ; Beate RITZ, Auteur ; Jasveer VIRK, Auteur ; Jørn OLSEN, Auteur . - p.951-958. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.951-958 Mots-clés : acetaminophen  autism spectrum disorders  infantile autism  childhood behavior  prenatal exposure  pregnancy cohort Index. décimale : PER Périodiques Résumé : Acetaminophen (paracetamol) is the most commonly used pain and fever medication during pregnancy. Previously, a positive ecological correlation between acetaminophen use and autism spectrum disorders (ASD) has been reported but evidence from larger studies based on prospective data is lacking. We followed 64,322 children and mothers enrolled in the Danish National Birth Cohort (DNBC; 1996–2002) for average 12.7 years to investigate whether acetaminophen use in pregnancy is associated with increased risk of ASD in the offspring. Information on acetaminophen use was collected prospectively from three computer-assisted telephone interviews. We used records from the Danish hospital and psychiatric registries to identify diagnoses of ASD. At the end of follow up, 1,027 (1.6%) children were diagnosed with ASD, 345 (0.5%) with infantile autism. We found that 31% of ASD (26% of infantile autism) have also been diagnosed with hyperkinetic disorders. More than 50% women reported ever using acetaminophen in pregnancy. We used Cox proportional hazards model to estimate hazard ratio (HR) and 95% confident interval (CI). Prenatal use of acetaminophen was associated with an increased risk of ASD accompanied by hyperkinetic symptoms (HR?=?1.51 95% CI 1.19–1.92), but not with other ASD cases (HR?=?1.06 95% CI 0.92–1.24). Longer duration of use (i.e., use for >20 weeks in gestation) increased the risk of ASD or infantile autism with hyperkinetic symptoms almost twofold. Maternal use of acetaminophen in pregnancy was associated with ASD with hyperkinetic symptoms only, suggesting acetaminophen exposure early in fetal life may specifically impact this hyperactive behavioral phenotype. Autism Res 2016, 9: 951–958. En ligne : http://dx.doi.org/10.1002/aur.1591 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

Functioning and disability in autism spectrum disorder: A worldwide survey of experts / Elles DE SCHIPPER in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.959-969 Titre : Functioning and disability in autism spectrum disorder: A worldwide survey of experts Type de document : Texte imprimé et/ou numérique Auteurs : Elles DE SCHIPPER, Auteur ; Soheil MAHDI, Auteur ; Petrus DE VRIES, Auteur ; Mats GRANLUND, Auteur ; Martin HOLTMANN, Auteur ; Sunil KARANDE, Auteur ; Omar ALMODAYFER, Auteur ; Cory SHULMAN, Auteur ; Bruce TONGE, Auteur ; Virginia C.N. WONG, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.959-969 Langues : Anglais (eng) Mots-clés : autism  neurodevelopmental disorder  assessment  child psychiatry  heterogeneity  quality of life Index. décimale : PER Périodiques Résumé : Objective: This study is the second of four to prepare International Classification of Functioning, Disability and Health (ICF; and Children and Youth version, ICF(-CY)) Core Sets for Autism Spectrum Disorder (ASD).The objective of this study was to survey the opinions and experiences of international experts on functioning and disability in ASD. Methods: Using a protocol stipulated by the World Health Organization (WHO) and monitored by the ICF Research Branch, an email-based questionnaire was circulated worldwide among ASD experts, and meaningful functional ability and disability concepts were extracted from their responses. These concepts were then linked to the ICF(-CY) by two independent researchers using a standardized linking procedure. Results: N?=?225 experts from 10 different disciplines and all six WHO-regions completed the survey. Meaningful concepts from the responses were linked to 210 ICF(-CY) categories. Of these, 103 categories were considered most relevant to ASD (i.e., identified by at least 5% of the experts), of which 37 were related to Activities and Participation, 35 to Body functions, 22 to Environmental factors, and 9 to Body structures. A variety of personal characteristics and ASD-related functioning skills were provided by experts, including honesty, loyalty, attention to detail and creative talents. Reported gender differences in ASD comprised more externalizing behaviors among males and more internalizing behaviors in females. Conclusion: The ICF(-CY) categories derived from international expert opinions indicate that the impact of ASD on functioning extends far beyond core symptom domains. Autism Res 2016, 9: 959–969. En ligne : http://dx.doi.org/10.1002/aur.1592 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Functioning and disability in autism spectrum disorder: A worldwide survey of experts [Texte imprimé et/ou numérique] / Elles DE SCHIPPER, Auteur ; Soheil MAHDI, Auteur ; Petrus DE VRIES, Auteur ; Mats GRANLUND, Auteur ; Martin HOLTMANN, Auteur ; Sunil KARANDE, Auteur ; Omar ALMODAYFER, Auteur ; Cory SHULMAN, Auteur ; Bruce TONGE, Auteur ; Virginia C.N. WONG, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Sven BÖLTE, Auteur . - p.959-969. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.959-969 Mots-clés : autism  neurodevelopmental disorder  assessment  child psychiatry  heterogeneity  quality of life Index. décimale : PER Périodiques Résumé : Objective: This study is the second of four to prepare International Classification of Functioning, Disability and Health (ICF; and Children and Youth version, ICF(-CY)) Core Sets for Autism Spectrum Disorder (ASD).The objective of this study was to survey the opinions and experiences of international experts on functioning and disability in ASD. Methods: Using a protocol stipulated by the World Health Organization (WHO) and monitored by the ICF Research Branch, an email-based questionnaire was circulated worldwide among ASD experts, and meaningful functional ability and disability concepts were extracted from their responses. These concepts were then linked to the ICF(-CY) by two independent researchers using a standardized linking procedure. Results: N?=?225 experts from 10 different disciplines and all six WHO-regions completed the survey. Meaningful concepts from the responses were linked to 210 ICF(-CY) categories. Of these, 103 categories were considered most relevant to ASD (i.e., identified by at least 5% of the experts), of which 37 were related to Activities and Participation, 35 to Body functions, 22 to Environmental factors, and 9 to Body structures. A variety of personal characteristics and ASD-related functioning skills were provided by experts, including honesty, loyalty, attention to detail and creative talents. Reported gender differences in ASD comprised more externalizing behaviors among males and more internalizing behaviors in females. Conclusion: The ICF(-CY) categories derived from international expert opinions indicate that the impact of ASD on functioning extends far beyond core symptom domains. Autism Res 2016, 9: 959–969. En ligne : http://dx.doi.org/10.1002/aur.1592 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

The social responsiveness scale in relation to DSM IV and DSM5 ASD in Korean children / Keun-Ah CHEON in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.970-980 Titre : The social responsiveness scale in relation to DSM IV and DSM5 ASD in Korean children Type de document : Texte imprimé et/ou numérique Auteurs : Keun-Ah CHEON, Auteur ; Jee-In PARK, Auteur ; Yun-Joo KOH, Auteur ; Jungeun SONG, Auteur ; Hyun-Joo HONG, Auteur ; Young-Kee KIM, Auteur ; Eun-Chung LIM, Auteur ; Hojang KWON, Auteur ; Mina HA, Auteur ; Myung-Ho LIM, Auteur ; Ki-Chung PAIK, Auteur ; John N. CONSTANTINO, Auteur ; Bennett L. LEVENTHAL, Auteur ; Young Shin KIM, Auteur Article en page(s) : p.970-980 Langues : Anglais (eng) Mots-clés : Korean social responsiveness scale  validity  reliability  DSM IV PDD  DSM5 ASD Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale (SRS) is an autism rating scales in widespread use, with over 20 official foreign language translations. It has proven highly feasible for quantitative ascertainment of autistic social impairment in public health settings, however, little is known about the validity of the reinforcement in Asia populations or in references to DSM5. The current study aims to evaluate psychometric properties and cross-cultural aspects of the SRS-Korean version (K-SRS).The study subjects were ascertained from three samples: a general sample from 3 regular education elementary schools (n=790), a clinical sample (n=154) of 6–12-year-olds from four psychiatric clinics, and an epidemiological sample of children with ASD, diagnosed using both DSM IV PDD, DSM5 ASD and SCD criteria (n=151). Their parents completed the K-SRS and the Autism Spectrum Screening Questionnaire(ASSQ). Descriptive statistics, correlation analyses and principal components analysis (PCA) were performed on the total population. Mean total scores on the K-SRS differed significantly between the three samples. ASSQ scores were significantly correlated with the K-SRS T-scores. PCA suggested a one-factor solution for the total population.Our results indicate that the K-SRS exhibits adequate reliability and validity for measuring ASD symptoms in Korean children with DSM IV PDD and DSM5 ASD. Our findings further suggest that it is difficult to distinguish SCD from other child psychiatric conditions using the K-SRS.This is the first study to examine the relationship between the SRS subscales and DSM5-based clinical diagnoses. This study provides cross-cultural confirmation of the factor structure for ASD symptoms and traits measured by the SRS. Autism Res 2016, 9: 970–980. En ligne : http://dx.doi.org/10.1002/aur.1671 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] The social responsiveness scale in relation to DSM IV and DSM5 ASD in Korean children [Texte imprimé et/ou numérique] / Keun-Ah CHEON, Auteur ; Jee-In PARK, Auteur ; Yun-Joo KOH, Auteur ; Jungeun SONG, Auteur ; Hyun-Joo HONG, Auteur ; Young-Kee KIM, Auteur ; Eun-Chung LIM, Auteur ; Hojang KWON, Auteur ; Mina HA, Auteur ; Myung-Ho LIM, Auteur ; Ki-Chung PAIK, Auteur ; John N. CONSTANTINO, Auteur ; Bennett L. LEVENTHAL, Auteur ; Young Shin KIM, Auteur . - p.970-980. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.970-980 Mots-clés : Korean social responsiveness scale  validity  reliability  DSM IV PDD  DSM5 ASD Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale (SRS) is an autism rating scales in widespread use, with over 20 official foreign language translations. It has proven highly feasible for quantitative ascertainment of autistic social impairment in public health settings, however, little is known about the validity of the reinforcement in Asia populations or in references to DSM5. The current study aims to evaluate psychometric properties and cross-cultural aspects of the SRS-Korean version (K-SRS).The study subjects were ascertained from three samples: a general sample from 3 regular education elementary schools (n=790), a clinical sample (n=154) of 6–12-year-olds from four psychiatric clinics, and an epidemiological sample of children with ASD, diagnosed using both DSM IV PDD, DSM5 ASD and SCD criteria (n=151). Their parents completed the K-SRS and the Autism Spectrum Screening Questionnaire(ASSQ). Descriptive statistics, correlation analyses and principal components analysis (PCA) were performed on the total population. Mean total scores on the K-SRS differed significantly between the three samples. ASSQ scores were significantly correlated with the K-SRS T-scores. PCA suggested a one-factor solution for the total population.Our results indicate that the K-SRS exhibits adequate reliability and validity for measuring ASD symptoms in Korean children with DSM IV PDD and DSM5 ASD. Our findings further suggest that it is difficult to distinguish SCD from other child psychiatric conditions using the K-SRS.This is the first study to examine the relationship between the SRS subscales and DSM5-based clinical diagnoses. This study provides cross-cultural confirmation of the factor structure for ASD symptoms and traits measured by the SRS. Autism Res 2016, 9: 970–980. En ligne : http://dx.doi.org/10.1002/aur.1671 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

White matter volume in the brainstem and inferior parietal lobule is related to motor performance in children with autism spectrum disorder: A voxel-based morphometry study / Ryuzo HANAIE in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.981-992 Titre : White matter volume in the brainstem and inferior parietal lobule is related to motor performance in children with autism spectrum disorder: A voxel-based morphometry study Type de document : Texte imprimé et/ou numérique Auteurs : Ryuzo HANAIE, Auteur ; Ikuko MOHRI, Auteur ; Kuriko KAGITANI-SHIMONO, Auteur ; Masaya TACHIBANA, Auteur ; Junko MATSUZAKI, Auteur ; Ikuko HIRATA, Auteur ; Fumiyo NAGATANI, Auteur ; Yoshiyuki WATANABE, Auteur ; Norihiko FUJITA, Auteur ; Masako TANIIKE, Auteur Article en page(s) : p.981-992 Langues : Anglais (eng) Mots-clés : voxel-based morphometry  white matter  brainstem  autism spectrum disorder  motor Index. décimale : PER Périodiques Résumé : Many studies have reported poor motor performance in autism spectrum disorder (ASD); however, the underlying brain mechanisms remain unclear. Recent neuroimaging studies have suggested that abnormalities of the white matter (WM) are related to the features of ASD. In this study, we used voxel-based morphometry (VBM) to investigate which WM regions correlate with motor performance in children with ASD, and whether the WM volume in those brain regions differed between children with ASD and typically developing (TD) children. The subjects included 19 children with ASD and 20 TD controls. Motor performance was assessed using the Movement Assessment Battery for Children 2 (M-ABC 2). Children with ASD showed poorer motor performance than did the controls. There was a significant positive correlation between the total test score on the M-ABC 2 and the volume of WM in the brainstem and WM adjacent to the left supramarginal gyrus (SMG). In addition, compared with the TD controls, children with ASD had a decreased volume of WM in the brainstem and adjacent to the left intraparietal sulcus, which is close to the SMG. These findings suggest that structural changes in the WM in the brainstem and left inferior parietal lobule may contribute to poor motor performance in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1605 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] White matter volume in the brainstem and inferior parietal lobule is related to motor performance in children with autism spectrum disorder: A voxel-based morphometry study [Texte imprimé et/ou numérique] / Ryuzo HANAIE, Auteur ; Ikuko MOHRI, Auteur ; Kuriko KAGITANI-SHIMONO, Auteur ; Masaya TACHIBANA, Auteur ; Junko MATSUZAKI, Auteur ; Ikuko HIRATA, Auteur ; Fumiyo NAGATANI, Auteur ; Yoshiyuki WATANABE, Auteur ; Norihiko FUJITA, Auteur ; Masako TANIIKE, Auteur . - p.981-992. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.981-992 Mots-clés : voxel-based morphometry  white matter  brainstem  autism spectrum disorder  motor Index. décimale : PER Périodiques Résumé : Many studies have reported poor motor performance in autism spectrum disorder (ASD); however, the underlying brain mechanisms remain unclear. Recent neuroimaging studies have suggested that abnormalities of the white matter (WM) are related to the features of ASD. In this study, we used voxel-based morphometry (VBM) to investigate which WM regions correlate with motor performance in children with ASD, and whether the WM volume in those brain regions differed between children with ASD and typically developing (TD) children. The subjects included 19 children with ASD and 20 TD controls. Motor performance was assessed using the Movement Assessment Battery for Children 2 (M-ABC 2). Children with ASD showed poorer motor performance than did the controls. There was a significant positive correlation between the total test score on the M-ABC 2 and the volume of WM in the brainstem and WM adjacent to the left supramarginal gyrus (SMG). In addition, compared with the TD controls, children with ASD had a decreased volume of WM in the brainstem and adjacent to the left intraparietal sulcus, which is close to the SMG. These findings suggest that structural changes in the WM in the brainstem and left inferior parietal lobule may contribute to poor motor performance in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1605 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

Early gross motor skills predict the subsequent development of language in children with autism spectrum disorder / Rachael BEDFORD in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.993-1001 Titre : Early gross motor skills predict the subsequent development of language in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Rachael BEDFORD, Auteur ; Andrew PICKLES, Auteur ; Catherine LORD, Auteur Article en page(s) : p.993-1001 Langues : Anglais (eng) Mots-clés : walking  language development  autism spectrum disorder Index. décimale : PER Périodiques Résumé : Background: Motor milestones such as the onset of walking are important developmental markers, not only for later motor skills but also for more widespread social-cognitive development. The aim of the current study was to test whether gross motor abilities, specifically the onset of walking, predicted the subsequent rate of language development in a large cohort of children with autism spectrum disorder (ASD). Methods: We ran growth curve models for expressive and receptive language measured at 2, 3, 5 and 9 years in 209 autistic children. Measures of gross motor, visual reception and autism symptoms were collected at the 2 year visit. In Model 1, walking onset was included as a predictor of the slope of language development. Model 2 included a measure of non-verbal IQ and autism symptom severity as covariates. The final model, Model 3, additionally covaried for gross motor ability. Results: In the first model, parent-reported age of walking onset significantly predicted the subsequent rate of language development although the relationship became non-significant when gross motor skill, non-verbal ability and autism severity scores were included (Models 2 & 3). Gross motor score, however, did remain a significant predictor of both expressive and receptive language development. Conclusions: Taken together, the model results provide some evidence that early motor abilities in young children with ASD can have longitudinal cross-domain influences, potentially contributing, in part, to the linguistic difficulties that characterise ASD. En ligne : http://dx.doi.org/10.1002/aur.1587 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Early gross motor skills predict the subsequent development of language in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Rachael BEDFORD, Auteur ; Andrew PICKLES, Auteur ; Catherine LORD, Auteur . - p.993-1001. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.993-1001 Mots-clés : walking  language development  autism spectrum disorder Index. décimale : PER Périodiques Résumé : Background: Motor milestones such as the onset of walking are important developmental markers, not only for later motor skills but also for more widespread social-cognitive development. The aim of the current study was to test whether gross motor abilities, specifically the onset of walking, predicted the subsequent rate of language development in a large cohort of children with autism spectrum disorder (ASD). Methods: We ran growth curve models for expressive and receptive language measured at 2, 3, 5 and 9 years in 209 autistic children. Measures of gross motor, visual reception and autism symptoms were collected at the 2 year visit. In Model 1, walking onset was included as a predictor of the slope of language development. Model 2 included a measure of non-verbal IQ and autism symptom severity as covariates. The final model, Model 3, additionally covaried for gross motor ability. Results: In the first model, parent-reported age of walking onset significantly predicted the subsequent rate of language development although the relationship became non-significant when gross motor skill, non-verbal ability and autism severity scores were included (Models 2 & 3). Gross motor score, however, did remain a significant predictor of both expressive and receptive language development. Conclusions: Taken together, the model results provide some evidence that early motor abilities in young children with ASD can have longitudinal cross-domain influences, potentially contributing, in part, to the linguistic difficulties that characterise ASD. En ligne : http://dx.doi.org/10.1002/aur.1587 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

A selective impairment in extracting fearful information from another's eyes in Autism / Yongning SONG in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.1002-1011 Titre : A selective impairment in extracting fearful information from another's eyes in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Yongning SONG, Auteur ; Yuji HAKODA, Auteur ; Biao SANG, Auteur Article en page(s) : p.1002-1011 Langues : Anglais (eng) Mots-clés : poor eye gaze  autism spectrum disorders  social cognition  bubbles Index. décimale : PER Périodiques Résumé : An atypical pattern of facial expression processing in children with autism spectrum disorder (ASD) has been discussed in previous studies. In this study, we systematically examined the hypothesis of selective abnormality of gaze pattern of in children with ASD using three emotion judgment “bubble” tasks. In this study, we used a data-driven driven technique, referred to as “Bubbles” to examine the hypothesis that ASD children will not show a general but rather a selective abnormality in extracting eyes information expressed by different emotions. Results indicated that similar to non-ASD individuals, ASD individuals used information from other people's eyes to judge happiness and anger. In contrast, ASD individuals showed a remarkable reduction in processing the eye region in fearful face, together with enhanced processing of the mouth, compared with the control group. The results suggest that a selective abnormality in extracting eyes information of fearful face without abnormality in processing eyes area of other basic facial emotions is a key and characteristic feature of autistic facial cognition. To our knowledge, this finding regarding the selective abnormality in extracting fearful information from another's eyes in ASDs has never been reported in previous studies and the information gathered as a part of this pilot research project has important clinical implications for social information processing training. For example, as children with ASD are more vulnerable to fear processing, training related to fear should be stressed. En ligne : http://dx.doi.org/10.1002/aur.1583 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] A selective impairment in extracting fearful information from another's eyes in Autism [Texte imprimé et/ou numérique] / Yongning SONG, Auteur ; Yuji HAKODA, Auteur ; Biao SANG, Auteur . - p.1002-1011. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.1002-1011 Mots-clés : poor eye gaze  autism spectrum disorders  social cognition  bubbles Index. décimale : PER Périodiques Résumé : An atypical pattern of facial expression processing in children with autism spectrum disorder (ASD) has been discussed in previous studies. In this study, we systematically examined the hypothesis of selective abnormality of gaze pattern of in children with ASD using three emotion judgment “bubble” tasks. In this study, we used a data-driven driven technique, referred to as “Bubbles” to examine the hypothesis that ASD children will not show a general but rather a selective abnormality in extracting eyes information expressed by different emotions. Results indicated that similar to non-ASD individuals, ASD individuals used information from other people's eyes to judge happiness and anger. In contrast, ASD individuals showed a remarkable reduction in processing the eye region in fearful face, together with enhanced processing of the mouth, compared with the control group. The results suggest that a selective abnormality in extracting eyes information of fearful face without abnormality in processing eyes area of other basic facial emotions is a key and characteristic feature of autistic facial cognition. To our knowledge, this finding regarding the selective abnormality in extracting fearful information from another's eyes in ASDs has never been reported in previous studies and the information gathered as a part of this pilot research project has important clinical implications for social information processing training. For example, as children with ASD are more vulnerable to fear processing, training related to fear should be stressed. En ligne : http://dx.doi.org/10.1002/aur.1583 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

Scientific Summaries for Families with ASD in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.1012-1015 Titre : Scientific Summaries for Families with ASD Type de document : Texte imprimé et/ou numérique Article en page(s) : p.1012-1015 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1712 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Scientific Summaries for Families with ASD [Texte imprimé et/ou numérique] . - p.1012-1015. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.1012-1015 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1712 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

International society for autism research news www.autism-insar.org INSAR policy brief: Request for proposals in Autism Research, 9-9 (September 2016)  

Public ISBD [article]  inAutism Research > 9-9 (September 2016) . - p.1016-1016 Titre : International society for autism research news www.autism-insar.org INSAR policy brief: Request for proposals Type de document : Texte imprimé et/ou numérique Article en page(s) : p.1016-1016 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1713 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] International society for autism research news www.autism-insar.org INSAR policy brief: Request for proposals [Texte imprimé et/ou numérique] . - p.1016-1016. Langues : Anglais (eng) in Autism Research > 9-9 (September 2016) . - p.1016-1016 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1713 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294