[article] 
inJournal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2624-2627

Titre :	Brief Report: A Longitudinal Study of Excessive Smiling and Laughing in Children with Angelman Syndrome
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Dawn ADAMS, Auteur ; Kate HORSLER, Auteur ; Rebecca MOUNT, Auteur ; Chris OLIVER, Auteur
Année de publication :	2015
Article en page(s) :	p.2624-2627
Langues :	Anglais (eng)
Mots-clés :	Angelman syndrome  Behavioral phenotype  Intellectual disability  Aging  Behavior
Index. décimale :	PER Périodiques
Résumé :	Elevated laughing and smiling is a key characteristic of the Angelman syndrome behavioral phenotype, with cross-sectional studies reporting changes with environment and age. This study compares levels of laughing and smiling in 12 participants across three experimental conditions [full social interaction (with eye contact), social interaction with no eye contact, proximity only] at two data points. No differences were noted in frequency of laughing and smiling over time in any condition. However, with age as a covariate, the frequency of laughing and smiling decreased over time in the full social interaction (with eye contact) condition only. As this is the first longitudinal study to explore these behaviors in Angelman syndrome, the results suggest a gene–environment–time interaction within the behavioral phenotype.
En ligne :	http://dx.doi.org/10.1007/s10803-015-2404-y
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263

[article] Brief Report: A Longitudinal Study of Excessive Smiling and Laughing in Children with Angelman Syndrome [Texte imprimé et/ou numérique] / Dawn ADAMS, Auteur ; Kate HORSLER, Auteur ; Rebecca MOUNT, Auteur ; Chris OLIVER, Auteur . - 2015 . - p.2624-2627.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2624-2627

Mots-clés :	Angelman syndrome  Behavioral phenotype  Intellectual disability  Aging  Behavior
Index. décimale :	PER Périodiques
Résumé :	Elevated laughing and smiling is a key characteristic of the Angelman syndrome behavioral phenotype, with cross-sectional studies reporting changes with environment and age. This study compares levels of laughing and smiling in 12 participants across three experimental conditions [full social interaction (with eye contact), social interaction with no eye contact, proximity only] at two data points. No differences were noted in frequency of laughing and smiling over time in any condition. However, with age as a covariate, the frequency of laughing and smiling decreased over time in the full social interaction (with eye contact) condition only. As this is the first longitudinal study to explore these behaviors in Angelman syndrome, the results suggest a gene–environment–time interaction within the behavioral phenotype.
En ligne :	http://dx.doi.org/10.1007/s10803-015-2404-y
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263