[article] 
inDevelopment and Psychopathology > 30-4 (October 2018) . - p.1503-1515

Titre :	Developmental relations between amygdala volume and anxiety traits: Effects of informant, sex, and age
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Katherine RICE WARNELL, Auteur ; Meredith PECUKONIS, Auteur ; Elizabeth REDCAY, Auteur
Article en page(s) :	p.1503-1515
Langues :	Anglais (eng)
Index. décimale :	PER Périodiques
Résumé :	Although substantial human and animal evidence suggests a role for the amygdala in anxiety, literature linking amygdala volume to anxiety symptomatology is inconclusive, with studies finding positive, negative, and null results. Clarifying this brain–behavior relation in middle to late childhood is especially important, as this is a time both of amygdala structural maturation and the emergence of many anxiety disorders. The goal of the current study was to clarify inconsistent findings in previous literature by identifying factors moderating the relation between amygdala volume and anxiety traits in a large sample of typically developing children aged 6–13 years (N = 72). In particular, we investigated the moderating effects of informant (parent vs. child), age, and sex. We found that children's reports (i.e., self-reports) were related to amygdala volume; children who reported higher anxiety levels had smaller amygdalae. This negative relation between amygdala volume and anxiety weakened with age. There was also an independent effect of sex, such that relations were stronger in males than in females. These results indicate the importance of considering sample and informant characteristics when charting the neurobiological mechanisms underlying developmental anxiety.
En ligne :	http://dx.doi.org/10.1017/S0954579417001626
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368

[article] Developmental relations between amygdala volume and anxiety traits: Effects of informant, sex, and age [Texte imprimé et/ou numérique] / Katherine RICE WARNELL, Auteur ; Meredith PECUKONIS, Auteur ; Elizabeth REDCAY, Auteur . - p.1503-1515.
Langues : Anglais (eng)
in Development and Psychopathology > 30-4 (October 2018) . - p.1503-1515

Index. décimale :	PER Périodiques
Résumé :	Although substantial human and animal evidence suggests a role for the amygdala in anxiety, literature linking amygdala volume to anxiety symptomatology is inconclusive, with studies finding positive, negative, and null results. Clarifying this brain–behavior relation in middle to late childhood is especially important, as this is a time both of amygdala structural maturation and the emergence of many anxiety disorders. The goal of the current study was to clarify inconsistent findings in previous literature by identifying factors moderating the relation between amygdala volume and anxiety traits in a large sample of typically developing children aged 6–13 years (N = 72). In particular, we investigated the moderating effects of informant (parent vs. child), age, and sex. We found that children's reports (i.e., self-reports) were related to amygdala volume; children who reported higher anxiety levels had smaller amygdalae. This negative relation between amygdala volume and anxiety weakened with age. There was also an independent effect of sex, such that relations were stronger in males than in females. These results indicate the importance of considering sample and informant characteristics when charting the neurobiological mechanisms underlying developmental anxiety.
En ligne :	http://dx.doi.org/10.1017/S0954579417001626
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368