[article]
Titre : |
Meta-analysis of randomized, controlled treatment trials for pediatric obsessive-compulsive disorder |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Hunna J. WATSON, Auteur ; Clare S. REES, Auteur |
Année de publication : |
2008 |
Article en page(s) : |
p.489-498 |
Langues : |
Anglais (eng) |
Mots-clés : |
Child/adolescent-obsessive-compulsive-disorder pediatric meta-analysis cognitive-behavioral-therapy drug-therapy pharmacology psychotherapy |
Index. décimale : |
PER Périodiques |
Résumé : |
Objective: To conduct a meta-analysis on randomized, controlled treatment trials of pediatric obsessive-compulsive disorder (OCD).
Method: Studies were included if they employed randomized, controlled methodology and treated young people (19 years or under) with OCD. A comprehensive literature search identified 13 RCTs containing 10 pharmacotherapy to control comparisons (N = 1016) and five cognitive-behavioral therapy (CBT) to control comparisons (N = 161).
Results: Random effects modeling yielded statistically significant pooled effect size (ES) estimates for pharmacotherapy (ES = .48, 95% CI = .36 to .61, p < .00001) and CBT (ES = 1.45, 95% CI = .68 to 2.22, p = .002). The results were robust to publication bias.
Conclusions: This is the first meta-analysis of treatment RCTs for pediatric OCD. CBT and pharmacotherapy were the only treatments effective beyond control in alleviating OCD symptoms. CBT showed a greater ES than pharmacotherapy. Previous meta-analyses that included uncontrolled trials exaggerated the efficacy of both treatments. |
En ligne : |
http://dx.doi.org/10.1111/j.1469-7610.2007.01875.x |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 |
in Journal of Child Psychology and Psychiatry > 49-5 (May 2008) . - p.489-498
|