Annual Research Review: Early adversity, the hypothalamic-pituitary-adrenocortical axis, and child psychopathology / K. J. KOSS in Journal of Child Psychology and Psychiatry, 59-4 (April 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-4 (April 2018) . - p.327-346 Titre : Annual Research Review: Early adversity, the hypothalamic-pituitary-adrenocortical axis, and child psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : K. J. KOSS, Auteur ; M. R. GUNNAR, Auteur Article en page(s) : p.327-346 Langues : Anglais (eng) Mots-clés : Early adversity  hypothalamic-pituitary-adrenocortical axis  psychopathology Index. décimale : PER Périodiques Résumé : BACKGROUND: Research on early adversity, stress biology, and child development has grown exponentially in recent years. FINDINGS: We review the current evidence for the hypothalamic-pituitary-adrenocortical (HPA) axis as a stress-mediating mechanism between various forms of childhood adversity and psychopathology. We begin with a review of the neurobiology of the axis and evidence for relations between early adversity-HPA axis activity and HPA axis activity-psychopathology, as well as discuss the role of regulatory mechanisms and sensitive periods in development. CONCLUSIONS: We call attention to critical gaps in the literature to highlight next steps in this research including focus on developmental timing, sex differences, stress buffering, and epigenetic regulation. A better understanding of individual differences in the adversity-HPA axis-psychopathology associations will require continued work addressing how multiple biological and behavioral systems work in concert to shape development. En ligne : http://dx.doi.org/10.1111/jcpp.12784 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=353 [article] Annual Research Review: Early adversity, the hypothalamic-pituitary-adrenocortical axis, and child psychopathology [Texte imprimé et/ou numérique] / K. J. KOSS, Auteur ; M. R. GUNNAR, Auteur . - p.327-346. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-4 (April 2018) . - p.327-346 Mots-clés : Early adversity  hypothalamic-pituitary-adrenocortical axis  psychopathology Index. décimale : PER Périodiques Résumé : BACKGROUND: Research on early adversity, stress biology, and child development has grown exponentially in recent years. FINDINGS: We review the current evidence for the hypothalamic-pituitary-adrenocortical (HPA) axis as a stress-mediating mechanism between various forms of childhood adversity and psychopathology. We begin with a review of the neurobiology of the axis and evidence for relations between early adversity-HPA axis activity and HPA axis activity-psychopathology, as well as discuss the role of regulatory mechanisms and sensitive periods in development. CONCLUSIONS: We call attention to critical gaps in the literature to highlight next steps in this research including focus on developmental timing, sex differences, stress buffering, and epigenetic regulation. A better understanding of individual differences in the adversity-HPA axis-psychopathology associations will require continued work addressing how multiple biological and behavioral systems work in concert to shape development. En ligne : http://dx.doi.org/10.1111/jcpp.12784 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=353

---

1 (1 - 1 / 1)