Continuity of behavioral and emotional problems from pre-school years to pre-adolescence in a developing country / Luciana ANSELMI in Journal of Child Psychology and Psychiatry, 49-5 (May 2008)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 49-5 (May 2008) . - p.499-507 Titre : Continuity of behavioral and emotional problems from pre-school years to pre-adolescence in a developing country Type de document : Texte imprimé et/ou numérique Auteurs : Luciana ANSELMI, Auteur ; Luis Augusto ROHDE, Auteur ; Fernando C. BARROS, Auteur ; Maycoln L.M. TEODORO, Auteur ; César A. PICCININI, Auteur ; Ana Maria B. MENEZES, Auteur ; Cora L. ARAUJO, Auteur Année de publication : 2008 Article en page(s) : p.499-507 Langues : Anglais (eng) Mots-clés : Behavior-problems continuity longitudinal-studies Third-World-children child-development externalizing-disorders Index. décimale : PER Périodiques Résumé : Background: All previous longitudinal community studies assessing the continuity of child behavioral/emotional problems were conducted in developed countries. Method: Six hundred and one children randomly selected from a Brazilian birth cohort were evaluated for behavioral/emotional problems through mother interview at 4 and 12 years with the same standard procedure – Child Behavior Checklist (CBCL). Results: CBCL Total Problem score presented a medium stability (r = .42) with externalizing problems showing higher stability and more homotypic continuity than internalizing problems. Of the children presenting deviant scores at the age of 4, only 31% remained deviant at the age of 12 (p < .001). A deviant CBCL Total Problem score at 12 years old was predicted by Rule-Breaking Behavior [OR = 7.46, 95% CI 2.76–20.19] and Social Problems [OR = 3.56, 95% CI 1.36–9.30] scores at 4 years of age. Either Rule-Breaking or Aggressive Behavior – externalizing syndromes – were part of the predictors for the three broad-band CBCL scores and six out of the eight CBCL syndromes. Conclusions: Behavioral/emotional problems in preschool children persist moderately up to pre-adolescence in a community sample. Externalizing problems at the age of 4 comprise the developmental history of most behavioral/emotional problems at pre-adolescence. Our findings concur with findings from developed countries and are quite similar for continuity, stability and predictability. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01865.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 [article] Continuity of behavioral and emotional problems from pre-school years to pre-adolescence in a developing country [Texte imprimé et/ou numérique] / Luciana ANSELMI, Auteur ; Luis Augusto ROHDE, Auteur ; Fernando C. BARROS, Auteur ; Maycoln L.M. TEODORO, Auteur ; César A. PICCININI, Auteur ; Ana Maria B. MENEZES, Auteur ; Cora L. ARAUJO, Auteur . - 2008 . - p.499-507. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 49-5 (May 2008) . - p.499-507 Mots-clés : Behavior-problems continuity longitudinal-studies Third-World-children child-development externalizing-disorders Index. décimale : PER Périodiques Résumé : Background: All previous longitudinal community studies assessing the continuity of child behavioral/emotional problems were conducted in developed countries. Method: Six hundred and one children randomly selected from a Brazilian birth cohort were evaluated for behavioral/emotional problems through mother interview at 4 and 12 years with the same standard procedure – Child Behavior Checklist (CBCL). Results: CBCL Total Problem score presented a medium stability (r = .42) with externalizing problems showing higher stability and more homotypic continuity than internalizing problems. Of the children presenting deviant scores at the age of 4, only 31% remained deviant at the age of 12 (p < .001). A deviant CBCL Total Problem score at 12 years old was predicted by Rule-Breaking Behavior [OR = 7.46, 95% CI 2.76–20.19] and Social Problems [OR = 3.56, 95% CI 1.36–9.30] scores at 4 years of age. Either Rule-Breaking or Aggressive Behavior – externalizing syndromes – were part of the predictors for the three broad-band CBCL scores and six out of the eight CBCL syndromes. Conclusions: Behavioral/emotional problems in preschool children persist moderately up to pre-adolescence in a community sample. Externalizing problems at the age of 4 comprise the developmental history of most behavioral/emotional problems at pre-adolescence. Our findings concur with findings from developed countries and are quite similar for continuity, stability and predictability. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01865.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386

Gene–environment interaction in externalizing problems among adolescents: evidence from the Pelotas 1993 Birth Cohort Study / Christian KIELING in Journal of Child Psychology and Psychiatry, 54-3 (March 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-3 (March 2013) . - p.298-304 Titre : Gene–environment interaction in externalizing problems among adolescents: evidence from the Pelotas 1993 Birth Cohort Study Type de document : Texte imprimé et/ou numérique Auteurs : Christian KIELING, Auteur ; Mara H. HUTZ, Auteur ; Júlia P. GENRO, Auteur ; Guilherme V. POLANCZYK, Auteur ; Luciana ANSELMI, Auteur ; Suzi CAMEY, Auteur ; Pedro C. HALLAL, Auteur ; Fernando C. BARROS, Auteur ; Cesar G. VICTORA, Auteur ; Ana Maria B. MENEZES, Auteur ; Luis Augusto ROHDE, Auteur Article en page(s) : p.298-304 Mots-clés : Gene–environment interaction  DAT1  maternal smoking  MAOA  childhood maltreatment  externalizing Index. décimale : PER Périodiques Résumé : Background: The study of gene–environment interactions (G × E) is one of the most promising strategies to uncover the origins of mental disorders. Replication of initial findings, however, is essential because there is a strong possibility of publication bias in the literature. In addition, there is a scarcity of research on the topic originated from low- and middle-income countries (LMIC). The aim of this study was to replicate G × E hypotheses for externalizing problems among adolescents in a middle-income country. Methods: As part of the Pelotas 1993 Birth Cohort Study, 5,249 children were enrolled at birth and followed up to the age of 15 years, with an 85.7% retention rate. We sought an interaction between the homozygosity of the 10-repeat allele at the dopamine transporter (DAT1) gene and prenatal maternal smoking in the development of hyperactivity problems during adolescence assessed by the Strengths and Difficulties Questionnaire. We also tested for an interaction between the uVNTR polymorphism at the monoamine oxidase A (MAOA) and the experience of childhood maltreatment in the occurrence of conduct problems among adolescent boys. Results: Although there was a clear association between prenatal maternal smoking and hyperactivity scores in adolescence (p 0.001), no main genetic or interaction effects for the DAT1 gene were detected. Similarly, childhood maltreatment showed to be associated with conduct problems among boys (p 0.001), with no observable main genetic or interaction effects for the MAOA gene. Conclusions: In the largest mental health G × E study performed in a LMIC to date, we did not replicate previous positive findings from the literature. Despite the presence of main environmental effects, there was no evidence of effect modification by genotype status. Additional replication efforts to measure G × E are needed to better understand the origins of mental health and illness, especially in LMIC. En ligne : http://dx.doi.org/10.1111/jcpp.12022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=191 [article] Gene–environment interaction in externalizing problems among adolescents: evidence from the Pelotas 1993 Birth Cohort Study [Texte imprimé et/ou numérique] / Christian KIELING, Auteur ; Mara H. HUTZ, Auteur ; Júlia P. GENRO, Auteur ; Guilherme V. POLANCZYK, Auteur ; Luciana ANSELMI, Auteur ; Suzi CAMEY, Auteur ; Pedro C. HALLAL, Auteur ; Fernando C. BARROS, Auteur ; Cesar G. VICTORA, Auteur ; Ana Maria B. MENEZES, Auteur ; Luis Augusto ROHDE, Auteur . - p.298-304. in Journal of Child Psychology and Psychiatry > 54-3 (March 2013) . - p.298-304 Mots-clés : Gene–environment interaction  DAT1  maternal smoking  MAOA  childhood maltreatment  externalizing Index. décimale : PER Périodiques Résumé : Background: The study of gene–environment interactions (G × E) is one of the most promising strategies to uncover the origins of mental disorders. Replication of initial findings, however, is essential because there is a strong possibility of publication bias in the literature. In addition, there is a scarcity of research on the topic originated from low- and middle-income countries (LMIC). The aim of this study was to replicate G × E hypotheses for externalizing problems among adolescents in a middle-income country. Methods: As part of the Pelotas 1993 Birth Cohort Study, 5,249 children were enrolled at birth and followed up to the age of 15 years, with an 85.7% retention rate. We sought an interaction between the homozygosity of the 10-repeat allele at the dopamine transporter (DAT1) gene and prenatal maternal smoking in the development of hyperactivity problems during adolescence assessed by the Strengths and Difficulties Questionnaire. We also tested for an interaction between the uVNTR polymorphism at the monoamine oxidase A (MAOA) and the experience of childhood maltreatment in the occurrence of conduct problems among adolescent boys. Results: Although there was a clear association between prenatal maternal smoking and hyperactivity scores in adolescence (p 0.001), no main genetic or interaction effects for the DAT1 gene were detected. Similarly, childhood maltreatment showed to be associated with conduct problems among boys (p 0.001), with no observable main genetic or interaction effects for the MAOA gene. Conclusions: In the largest mental health G × E study performed in a LMIC to date, we did not replicate previous positive findings from the literature. Despite the presence of main environmental effects, there was no evidence of effect modification by genotype status. Additional replication efforts to measure G × E are needed to better understand the origins of mental health and illness, especially in LMIC. En ligne : http://dx.doi.org/10.1111/jcpp.12022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=191

Increase in child behavior problems among urban Brazilian 4-year olds: 1993 and 2004 Pelotas birth cohorts / Alicia MATIJASEVICH in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1125-1134 Titre : Increase in child behavior problems among urban Brazilian 4-year olds: 1993 and 2004 Pelotas birth cohorts Type de document : Texte imprimé et/ou numérique Auteurs : Alicia MATIJASEVICH, Auteur ; Elizabeth MURRAY, Auteur ; Alan STEIN, Auteur ; Luciana ANSELMI, Auteur ; Ana M. MENEZES, Auteur ; Iná S. SANTOS, Auteur ; Aluísio J. D. BARROS, Auteur ; Denise P. GIGANTE, Auteur ; Fernando C. BARROS, Auteur ; Cesar G. VICTORA, Auteur Article en page(s) : p.1125-1134 Langues : Anglais (eng) Mots-clés : Mental health  behavior problems  child behavior check list  longitudinal studies Index. décimale : PER Périodiques Résumé : Background There are an increasing number of reports on time trends in child and adolescent psychological problems but none from low- and middle-income countries, and very few covering the preschool period. The aim was to investigate changes in preschool behavioral/emotional problems in two birth cohorts from a middle-income country born 11 years apart. Methods We analyzed data from the 1993 and 2004 Pelotas birth cohort studies from Brazil. A subsample of 4-year olds from the 1993 cohort (634) and all 4-year olds from the 2004 cohort (3750) were assessed for behavioral/emotional problems through maternal report using the Child Behavior Checklist (CBCL). Response rates in these two population-based cohorts were above 90%. Results We found a significant increase in CBCL total problems, internalizing and externalizing mean scores over the 11-year period. For 1993 and 2004 Pelotas cohorts, respectively, CBCL mean values (SE) total problems scores were 27.9 (0.8) and 34.7 (0.3); for internalizing scores, 5.7 (0.2) and 6.3 (0.1) and for externalizing scores, 12.4 (0.4) and 15.5 (0.1). After adjusting for confounding variables, the largest increase from 1993 to 2004 was identified in the aggressive behavior syndrome score (Cohen's d = .50), followed by the externalizing problem score (Cohen's d = .40) and CBCL total problem score (Cohen's d = .36), respectively. The rise in child psychological problems was more marked in children from families with fewer assets and with less educated mothers. Conclusions Our findings provide evidence for a substantial increase in preschool behavioral problems among children in Brazil over an 11-year period. En ligne : http://dx.doi.org/10.1111/jcpp.12236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Increase in child behavior problems among urban Brazilian 4-year olds: 1993 and 2004 Pelotas birth cohorts [Texte imprimé et/ou numérique] / Alicia MATIJASEVICH, Auteur ; Elizabeth MURRAY, Auteur ; Alan STEIN, Auteur ; Luciana ANSELMI, Auteur ; Ana M. MENEZES, Auteur ; Iná S. SANTOS, Auteur ; Aluísio J. D. BARROS, Auteur ; Denise P. GIGANTE, Auteur ; Fernando C. BARROS, Auteur ; Cesar G. VICTORA, Auteur . - p.1125-1134. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1125-1134 Mots-clés : Mental health  behavior problems  child behavior check list  longitudinal studies Index. décimale : PER Périodiques Résumé : Background There are an increasing number of reports on time trends in child and adolescent psychological problems but none from low- and middle-income countries, and very few covering the preschool period. The aim was to investigate changes in preschool behavioral/emotional problems in two birth cohorts from a middle-income country born 11 years apart. Methods We analyzed data from the 1993 and 2004 Pelotas birth cohort studies from Brazil. A subsample of 4-year olds from the 1993 cohort (634) and all 4-year olds from the 2004 cohort (3750) were assessed for behavioral/emotional problems through maternal report using the Child Behavior Checklist (CBCL). Response rates in these two population-based cohorts were above 90%. Results We found a significant increase in CBCL total problems, internalizing and externalizing mean scores over the 11-year period. For 1993 and 2004 Pelotas cohorts, respectively, CBCL mean values (SE) total problems scores were 27.9 (0.8) and 34.7 (0.3); for internalizing scores, 5.7 (0.2) and 6.3 (0.1) and for externalizing scores, 12.4 (0.4) and 15.5 (0.1). After adjusting for confounding variables, the largest increase from 1993 to 2004 was identified in the aggressive behavior syndrome score (Cohen's d = .50), followed by the externalizing problem score (Cohen's d = .40) and CBCL total problem score (Cohen's d = .36), respectively. The rise in child psychological problems was more marked in children from families with fewer assets and with less educated mothers. Conclusions Our findings provide evidence for a substantial increase in preschool behavioral problems among children in Brazil over an 11-year period. En ligne : http://dx.doi.org/10.1111/jcpp.12236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Perinatal and sociodemographic factors at birth predicting conduct problems and violence to age 18 years: comparison of Brazilian and British birth cohorts / Joseph MURRAY in Journal of Child Psychology and Psychiatry, 56-8 (August 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-8 (August 2015) . - p.914-922 Titre : Perinatal and sociodemographic factors at birth predicting conduct problems and violence to age 18 years: comparison of Brazilian and British birth cohorts Type de document : Texte imprimé et/ou numérique Auteurs : Joseph MURRAY, Auteur ; Barbara MAUGHAN, Auteur ; Ana M. B. MENEZES, Auteur ; Matthew HICKMAN, Auteur ; John MACLEOD, Auteur ; Alicia MATIJASEVICH, Auteur ; Helen GONÇALVES, Auteur ; Luciana ANSELMI, Auteur ; Erika A. G. GALLO, Auteur ; Fernando C. BARROS, Auteur Article en page(s) : p.914-922 Langues : Anglais (eng) Mots-clés : Conduct problems  violence  risk factors  cohort study  middle-income country  ALSPAC Index. décimale : PER Périodiques Résumé : Background Many low- and middle-income countries have high levels of violence. Research in high-income countries shows that risk factors in the perinatal period are significant precursors of conduct problems which can develop into violence. It is not known whether the same early influences are important in lower income settings with higher rates of violence. This study compared perinatal and sociodemographic risk factors between Brazil and Britain, and their role in explaining higher rates of conduct problems and violence in Brazil. Methods Prospective population-based birth cohort studies were conducted in Pelotas, Brazil (N = 3,618) and Avon, Britain (N = 4,103). Eleven perinatal and sociodemographic risk factors were measured in questionnaires completed by mothers during the perinatal period. Conduct problems were measured in questionnaires completed by mothers at age 11, and violence in self-report questionnaires completed by adolescents at age 18. Results Conduct problems were predicted by similar risk factors in Brazil and Britain. Female violence was predicted by several of the same risk factors in both countries. However, male violence in Brazil was associated with only one risk factor, and several risk factor associations were weaker in Brazil than in Britain for both females and males. Almost 20% of the higher risk for conduct problems in Brazil compared to Britain was explained by differential exposure to risk factors. The percentage of the cross-national difference in violence explained by early risk factors was 15% for females and 8% for males. Conclusions A nontrivial proportion of cross-national differences in antisocial behaviour are related to perinatal and sociodemographic conditions at the start of life. However, risk factor associations are weaker in Brazil than in Britain, and influences in other developmental periods are probably of particular importance for understanding male youth violence in Brazil. En ligne : http://dx.doi.org/10.1111/jcpp.12369 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263 [article] Perinatal and sociodemographic factors at birth predicting conduct problems and violence to age 18 years: comparison of Brazilian and British birth cohorts [Texte imprimé et/ou numérique] / Joseph MURRAY, Auteur ; Barbara MAUGHAN, Auteur ; Ana M. B. MENEZES, Auteur ; Matthew HICKMAN, Auteur ; John MACLEOD, Auteur ; Alicia MATIJASEVICH, Auteur ; Helen GONÇALVES, Auteur ; Luciana ANSELMI, Auteur ; Erika A. G. GALLO, Auteur ; Fernando C. BARROS, Auteur . - p.914-922. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-8 (August 2015) . - p.914-922 Mots-clés : Conduct problems  violence  risk factors  cohort study  middle-income country  ALSPAC Index. décimale : PER Périodiques Résumé : Background Many low- and middle-income countries have high levels of violence. Research in high-income countries shows that risk factors in the perinatal period are significant precursors of conduct problems which can develop into violence. It is not known whether the same early influences are important in lower income settings with higher rates of violence. This study compared perinatal and sociodemographic risk factors between Brazil and Britain, and their role in explaining higher rates of conduct problems and violence in Brazil. Methods Prospective population-based birth cohort studies were conducted in Pelotas, Brazil (N = 3,618) and Avon, Britain (N = 4,103). Eleven perinatal and sociodemographic risk factors were measured in questionnaires completed by mothers during the perinatal period. Conduct problems were measured in questionnaires completed by mothers at age 11, and violence in self-report questionnaires completed by adolescents at age 18. Results Conduct problems were predicted by similar risk factors in Brazil and Britain. Female violence was predicted by several of the same risk factors in both countries. However, male violence in Brazil was associated with only one risk factor, and several risk factor associations were weaker in Brazil than in Britain for both females and males. Almost 20% of the higher risk for conduct problems in Brazil compared to Britain was explained by differential exposure to risk factors. The percentage of the cross-national difference in violence explained by early risk factors was 15% for females and 8% for males. Conclusions A nontrivial proportion of cross-national differences in antisocial behaviour are related to perinatal and sociodemographic conditions at the start of life. However, risk factor associations are weaker in Brazil than in Britain, and influences in other developmental periods are probably of particular importance for understanding male youth violence in Brazil. En ligne : http://dx.doi.org/10.1111/jcpp.12369 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263

Sex differences in the association between foetal growth and child attention at age four: specific vulnerability of girls / Elizabeth MURRAY in Journal of Child Psychology and Psychiatry, 56-12 (December 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-12 (December 2015) . - p.1380-1388 Titre : Sex differences in the association between foetal growth and child attention at age four: specific vulnerability of girls Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth MURRAY, Auteur ; Alicia MATIJASEVICH, Auteur ; Iná S. SANTOS, Auteur ; Aluísio J. D. BARROS, Auteur ; Luciana ANSELMI, Auteur ; Fernando C. BARROS, Auteur ; Alan STEIN, Auteur Article en page(s) : p.1380-1388 Langues : Anglais (eng) Mots-clés : Gender  head circumference  low birth weight  ponderal index  small-for-gestational age  pelotas birth cohort Index. décimale : PER Périodiques Résumé : Background Recent evidence suggests that impaired foetal growth may provide an early indication of increased risk of child attention problems. However, despite both foetal growth and child attention problems differing by sex, few studies have examined sex differences in this association. Furthermore, no studies have been conducted in low- and middle-income countries, where there are higher rates of perinatal problems. This study aimed to test for sex differences in the association between foetal growth indices and attention problems at age four, in a large, prospective birth cohort from a middle-income country. Methods A total of 3,749 neonates from the 2004 Pelotas birth cohort (Brazil) with foetal growth indices collected at birth [low birthweight (LBW), small-for-gestational age (SGA), head circumference (HC), head circumference-to-abdominal circumference ratio (HC/AC) and ponderal index (PI)], were assessed for attention problems using the Child Behaviour Checklist at age four. Ordinal logistic regression with successive adjustment for maternal, demographic, gestational, perinatal and child nutrition/mother–child morbidity, was conducted separately for girls and boys. Results In girls, attention difficulties were associated with being born SGA (OR = 1.40, CI = 1.08–1.82, p = .012), with a small HC (OR = 1.52, CI = 1.11–2.08, p = .009), or with a low PI (OR = 1.29, CI = 1.08–1.54, p = .005). There were no associations identified between attention difficulties and any foetal growth indices in boys. Conclusions Our results show that girls with impaired foetal growth may be particularly at risk of attention difficulties in childhood. This is consistent with emerging research that female foetuses may be more vulnerable to certain suboptimal intrauterine environments, inducing epigenetic changes that lead to disturbed growth and long-term developmental impairment. En ligne : http://dx.doi.org/10.1111/jcpp.12422 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273 [article] Sex differences in the association between foetal growth and child attention at age four: specific vulnerability of girls [Texte imprimé et/ou numérique] / Elizabeth MURRAY, Auteur ; Alicia MATIJASEVICH, Auteur ; Iná S. SANTOS, Auteur ; Aluísio J. D. BARROS, Auteur ; Luciana ANSELMI, Auteur ; Fernando C. BARROS, Auteur ; Alan STEIN, Auteur . - p.1380-1388. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-12 (December 2015) . - p.1380-1388 Mots-clés : Gender  head circumference  low birth weight  ponderal index  small-for-gestational age  pelotas birth cohort Index. décimale : PER Périodiques Résumé : Background Recent evidence suggests that impaired foetal growth may provide an early indication of increased risk of child attention problems. However, despite both foetal growth and child attention problems differing by sex, few studies have examined sex differences in this association. Furthermore, no studies have been conducted in low- and middle-income countries, where there are higher rates of perinatal problems. This study aimed to test for sex differences in the association between foetal growth indices and attention problems at age four, in a large, prospective birth cohort from a middle-income country. Methods A total of 3,749 neonates from the 2004 Pelotas birth cohort (Brazil) with foetal growth indices collected at birth [low birthweight (LBW), small-for-gestational age (SGA), head circumference (HC), head circumference-to-abdominal circumference ratio (HC/AC) and ponderal index (PI)], were assessed for attention problems using the Child Behaviour Checklist at age four. Ordinal logistic regression with successive adjustment for maternal, demographic, gestational, perinatal and child nutrition/mother–child morbidity, was conducted separately for girls and boys. Results In girls, attention difficulties were associated with being born SGA (OR = 1.40, CI = 1.08–1.82, p = .012), with a small HC (OR = 1.52, CI = 1.11–2.08, p = .009), or with a low PI (OR = 1.29, CI = 1.08–1.54, p = .005). There were no associations identified between attention difficulties and any foetal growth indices in boys. Conclusions Our results show that girls with impaired foetal growth may be particularly at risk of attention difficulties in childhood. This is consistent with emerging research that female foetuses may be more vulnerable to certain suboptimal intrauterine environments, inducing epigenetic changes that lead to disturbed growth and long-term developmental impairment. En ligne : http://dx.doi.org/10.1111/jcpp.12422 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273

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