Audiovisual temporal integration and rapid temporal recalibration in adolescents and adults: Age-related changes and its correlation with autistic traits / Han-Yu ZHOU in Autism Research, 13-4 (April 2020)  

Public ISBD [article]  inAutism Research > 13-4 (April 2020) . - p.615-626 Titre : Audiovisual temporal integration and rapid temporal recalibration in adolescents and adults: Age-related changes and its correlation with autistic traits Type de document : Texte imprimé et/ou numérique Auteurs : Han-Yu ZHOU, Auteur ; Li-Juan SHI, Auteur ; Han-Xue YANG, Auteur ; Eric F. C. CHEUNG, Auteur ; Raymond C. K. CHAN, Auteur Article en page(s) : p.615-626 Langues : Anglais (eng) Mots-clés : adolescents  age effect  audiovisual integration  autistic traits  rapid temporal recalibration  temporal binding window Index. décimale : PER Périodiques Résumé : Temporal structure is a key factor in determining the relatedness of multisensory stimuli. Stimuli that are close in time are more likely to be integrated into a unified perceptual representation. To investigate the age-related developmental differences in audiovisual temporal integration and rapid temporal recalibration, we administered simultaneity judgment (SJ) tasks to a group of adolescents (11-14 years) and young adults (18-28 years). No age-related changes were found in the width of the temporal binding window within which participants are highly likely to combine multisensory stimuli. The main distinction between adolescents and adults was audiovisual temporal recalibration. Although participants of both age groups could rapidly recalibrate based on the previous trial for speech stimuli (i.e., syllable utterances), only adults but not adolescents showed short-term recalibration for simple and non-speech stimuli. In both adolescents and adults, no significant correlation was found between audiovisual temporal integration ability and autistic or schizotypal traits. These findings provide new information on the developmental trajectory of basic multisensory function and may have implications for neurodevelopmental disorders (e.g., autism) with altered audiovisual temporal integration. Autism Res 2020, 13: 615-626. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Utilizing temporal cues to integrate and separate audiovisual information is a fundamental ability underlying higher order social communicative functions. This study examines the developmental changes of the ability to detect audiovisual asynchrony and rapidly adjust sensory decisions based on previous sensory input. In healthy adolescents and young adults, the correlation between autistic traits and audiovisual integration ability failed to reach a significant level. Therefore, more research is needed to examine whether impairment in basic sensory functions is correlated with broader autism phenotype in nonclinical populations. These results may help us understand altered multisensory integration in people with autism. En ligne : http://dx.doi.org/10.1002/aur.2249 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421 [article] Audiovisual temporal integration and rapid temporal recalibration in adolescents and adults: Age-related changes and its correlation with autistic traits [Texte imprimé et/ou numérique] / Han-Yu ZHOU, Auteur ; Li-Juan SHI, Auteur ; Han-Xue YANG, Auteur ; Eric F. C. CHEUNG, Auteur ; Raymond C. K. CHAN, Auteur . - p.615-626. Langues : Anglais (eng) in Autism Research > 13-4 (April 2020) . - p.615-626 Mots-clés : adolescents  age effect  audiovisual integration  autistic traits  rapid temporal recalibration  temporal binding window Index. décimale : PER Périodiques Résumé : Temporal structure is a key factor in determining the relatedness of multisensory stimuli. Stimuli that are close in time are more likely to be integrated into a unified perceptual representation. To investigate the age-related developmental differences in audiovisual temporal integration and rapid temporal recalibration, we administered simultaneity judgment (SJ) tasks to a group of adolescents (11-14 years) and young adults (18-28 years). No age-related changes were found in the width of the temporal binding window within which participants are highly likely to combine multisensory stimuli. The main distinction between adolescents and adults was audiovisual temporal recalibration. Although participants of both age groups could rapidly recalibrate based on the previous trial for speech stimuli (i.e., syllable utterances), only adults but not adolescents showed short-term recalibration for simple and non-speech stimuli. In both adolescents and adults, no significant correlation was found between audiovisual temporal integration ability and autistic or schizotypal traits. These findings provide new information on the developmental trajectory of basic multisensory function and may have implications for neurodevelopmental disorders (e.g., autism) with altered audiovisual temporal integration. Autism Res 2020, 13: 615-626. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Utilizing temporal cues to integrate and separate audiovisual information is a fundamental ability underlying higher order social communicative functions. This study examines the developmental changes of the ability to detect audiovisual asynchrony and rapidly adjust sensory decisions based on previous sensory input. In healthy adolescents and young adults, the correlation between autistic traits and audiovisual integration ability failed to reach a significant level. Therefore, more research is needed to examine whether impairment in basic sensory functions is correlated with broader autism phenotype in nonclinical populations. These results may help us understand altered multisensory integration in people with autism. En ligne : http://dx.doi.org/10.1002/aur.2249 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421

Correlations Between Audiovisual Temporal Processing and Sensory Responsiveness in Adolescents with Autistic Traits / H. Y. ZHOU in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2450-2460 Titre : Correlations Between Audiovisual Temporal Processing and Sensory Responsiveness in Adolescents with Autistic Traits Type de document : Texte imprimé et/ou numérique Auteurs : H. Y. ZHOU, Auteur ; H. X. YANG, Auteur ; L. J. SHI, Auteur ; S. S. Y. LUI, Auteur ; Eric F. C. CHEUNG, Auteur ; R. C. K. CHAN, Auteur Article en page(s) : p.2450-2460 Langues : Anglais (eng) Mots-clés : Adolescent  Auditory Perception/physiology  Autism Spectrum Disorder/physiopathology  Female  Humans  Judgment  Male  Sensation/physiology  Sensory Thresholds  Task Performance and Analysis  Time Perception/physiology  Visual Perception/physiology  Audiovisual  Auditory  Autistic traits  Sensory responsiveness  Temporal acuity  Visual Index. décimale : PER Périodiques Résumé : Atypical sensory processing has recently gained much research interest as a key domain of autistic symptoms. Individuals with autism spectrum disorder (ASD) exhibit difficulties in processing the temporal aspects of sensory inputs, and show altered behavioural responses to sensory stimuli (i.e., sensory responsiveness). The present study examined the relation between sensory responsiveness (assessed by the Adult/Adolescent Sensory Profile) and audiovisual temporal integration (measured by unisensory temporal order judgement (TOJ) tasks and audiovisual simultaneity judgement (SJ) tasks) in typically-developing adolescents (n?=?94). We found that adolescents with higher levels of autistic traits exhibited more difficulties in separating visual stimuli in time (i.e., larger visual TOJ threshold) and showed a stronger bias to perceive sound-leading audiovisual pairings as simultaneous. Regarding the associations between different measures of sensory function, reduced visual temporal acuity, but not auditory or multisensory temporal processing, was significantly correlated with more atypical patterns of sensory responsiveness. Furthermore, the positive correlation between visual TOJ thresholds and sensory avoidance was only found in adolescents with relatively high levels of autistic traits, but not in those with relatively low levels of autistic traits. These findings suggest that reduced visual temporal acuity may contribute to altered sensory experiences and may be linked to broader behavioural characteristics of ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04724-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Correlations Between Audiovisual Temporal Processing and Sensory Responsiveness in Adolescents with Autistic Traits [Texte imprimé et/ou numérique] / H. Y. ZHOU, Auteur ; H. X. YANG, Auteur ; L. J. SHI, Auteur ; S. S. Y. LUI, Auteur ; Eric F. C. CHEUNG, Auteur ; R. C. K. CHAN, Auteur . - p.2450-2460. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2450-2460 Mots-clés : Adolescent  Auditory Perception/physiology  Autism Spectrum Disorder/physiopathology  Female  Humans  Judgment  Male  Sensation/physiology  Sensory Thresholds  Task Performance and Analysis  Time Perception/physiology  Visual Perception/physiology  Audiovisual  Auditory  Autistic traits  Sensory responsiveness  Temporal acuity  Visual Index. décimale : PER Périodiques Résumé : Atypical sensory processing has recently gained much research interest as a key domain of autistic symptoms. Individuals with autism spectrum disorder (ASD) exhibit difficulties in processing the temporal aspects of sensory inputs, and show altered behavioural responses to sensory stimuli (i.e., sensory responsiveness). The present study examined the relation between sensory responsiveness (assessed by the Adult/Adolescent Sensory Profile) and audiovisual temporal integration (measured by unisensory temporal order judgement (TOJ) tasks and audiovisual simultaneity judgement (SJ) tasks) in typically-developing adolescents (n?=?94). We found that adolescents with higher levels of autistic traits exhibited more difficulties in separating visual stimuli in time (i.e., larger visual TOJ threshold) and showed a stronger bias to perceive sound-leading audiovisual pairings as simultaneous. Regarding the associations between different measures of sensory function, reduced visual temporal acuity, but not auditory or multisensory temporal processing, was significantly correlated with more atypical patterns of sensory responsiveness. Furthermore, the positive correlation between visual TOJ thresholds and sensory avoidance was only found in adolescents with relatively high levels of autistic traits, but not in those with relatively low levels of autistic traits. These findings suggest that reduced visual temporal acuity may contribute to altered sensory experiences and may be linked to broader behavioural characteristics of ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04724-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

Differential profiles of response inhibition deficit between male children with autism spectrum disorders and schizophrenia / Li-Juan SHI in Autism Research, 13-4 (April 2020)  

Public ISBD [article]  inAutism Research > 13-4 (April 2020) . - p.591-602 Titre : Differential profiles of response inhibition deficit between male children with autism spectrum disorders and schizophrenia Type de document : Texte imprimé et/ou numérique Auteurs : Li-Juan SHI, Auteur ; Han-Yu ZHOU, Auteur ; Yan-Mei SHEN, Auteur ; Ya WANG, Auteur ; Yu-Min FANG, Auteur ; Yu-Qiong HE, Auteur ; Jian-Jun OU, Auteur ; Xue-Rong LUO, Auteur ; Eric F. C. CHEUNG, Auteur ; Raymond C. K. CHAN, Auteur Article en page(s) : p.591-602 Langues : Anglais (eng) Mots-clés : auditory  autism spectrum disorder  response inhibition  schizophrenia  verbal  visual Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) and schizophrenia (SZ) are both associated with response inhibition impairment. However, the relative pattern of deficits in these two disorders remains unclear. Twenty-three male children with ASD, 23 male children with SZ, and 32 typically developing male controls were recruited to complete a set of tasks measuring response inhibition in the visual, auditory, and verbal domains. We found that visual, auditory, and verbal response inhibitions were impaired in both children with ASD and children with SZ. Compared with typically developing controls, children with ASD made more commission errors whereas children with SZ responded much slower in the visual response inhibition task. Both clinical groups showed comparable impairment in verbal response inhibition, but children with SZ were more impaired in auditory response inhibition than children with ASD. These different patterns of response inhibition deficit between male children with ASD and SZ may help to differentiate between these two disorders and may be potential targets for intervention. Autism Res 2020, 13: 591-602. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: In this study, we found that male children with autism spectrum disorder (ASD) made more commission errors whereas male children with schizophrenia (SZ) responded much slower in the visual response inhibition task. Both clinical groups exhibited comparable impairments in verbal response inhibition, but male children with SZ were more impaired in auditory response inhibition than male children with ASD. Our findings provide potential targets for intervention. En ligne : http://dx.doi.org/10.1002/aur.2231 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421 [article] Differential profiles of response inhibition deficit between male children with autism spectrum disorders and schizophrenia [Texte imprimé et/ou numérique] / Li-Juan SHI, Auteur ; Han-Yu ZHOU, Auteur ; Yan-Mei SHEN, Auteur ; Ya WANG, Auteur ; Yu-Min FANG, Auteur ; Yu-Qiong HE, Auteur ; Jian-Jun OU, Auteur ; Xue-Rong LUO, Auteur ; Eric F. C. CHEUNG, Auteur ; Raymond C. K. CHAN, Auteur . - p.591-602. Langues : Anglais (eng) in Autism Research > 13-4 (April 2020) . - p.591-602 Mots-clés : auditory  autism spectrum disorder  response inhibition  schizophrenia  verbal  visual Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) and schizophrenia (SZ) are both associated with response inhibition impairment. However, the relative pattern of deficits in these two disorders remains unclear. Twenty-three male children with ASD, 23 male children with SZ, and 32 typically developing male controls were recruited to complete a set of tasks measuring response inhibition in the visual, auditory, and verbal domains. We found that visual, auditory, and verbal response inhibitions were impaired in both children with ASD and children with SZ. Compared with typically developing controls, children with ASD made more commission errors whereas children with SZ responded much slower in the visual response inhibition task. Both clinical groups showed comparable impairment in verbal response inhibition, but children with SZ were more impaired in auditory response inhibition than children with ASD. These different patterns of response inhibition deficit between male children with ASD and SZ may help to differentiate between these two disorders and may be potential targets for intervention. Autism Res 2020, 13: 591-602. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: In this study, we found that male children with autism spectrum disorder (ASD) made more commission errors whereas male children with schizophrenia (SZ) responded much slower in the visual response inhibition task. Both clinical groups exhibited comparable impairments in verbal response inhibition, but male children with SZ were more impaired in auditory response inhibition than male children with ASD. Our findings provide potential targets for intervention. En ligne : http://dx.doi.org/10.1002/aur.2231 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421

Meta-analysis of neuropsychological measures of executive functioning in children and adolescents with high-functioning autism spectrum disorder / Chun Lun Eric LAI in Autism Research, 10-5 (May 2017)  

Public ISBD [article]  inAutism Research > 10-5 (May 2017) . - p.911-939 Titre : Meta-analysis of neuropsychological measures of executive functioning in children and adolescents with high-functioning autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Chun Lun Eric LAI, Auteur ; Zoe LAU, Auteur ; Simon S. Y. LUI, Auteur ; Eugenia LOK, Auteur ; Venus TAM, Auteur ; Quinney CHAN, Auteur ; Koi Man CHENG, Auteur ; Siu Man LAM, Auteur ; Eric F. C. CHEUNG, Auteur Article en page(s) : p.911-939 Langues : Anglais (eng) Mots-clés : executive function  high-functioning autism spectrum disorder  Asperger's syndrome  meta-analysis Index. décimale : PER Périodiques Résumé : Existing literature on the profile of executive dysfunction in autism spectrum disorder showed inconsistent results. Age, comorbid attention-deficit/hyperactivity disorder (ADHD) and cognitive abilities appeared to play a role in confounding the picture. Previous meta-analyses have focused on a few components of executive functions. This meta-analysis attempted to delineate the profile of deficit in several components of executive functioning in children and adolescents with high-functioning autism spectrum disorder (HFASD). Ninety-eight English published case-control studies comparing children and adolescents with HFASD with typically developing controls using well-known neuropsychological measures to assess executive functions were included. Results showed that children and adolescents with HFASD were moderately impaired in verbal working memory (g?=?0.67), spatial working memory (g?=?0.58), flexibility (g?=?0.59), planning (g?=?0.62), and generativity (g?=?0.60) except for inhibition (g?=?0.41). Subgroup analysis showed that impairments were still significant for flexibility (g?=?0.57–0.61), generativity (g?=?0.52–0.68), and working memory (g?=?0.49–0.56) in a sample of autism spectrum disorder (ASD) subjects without comorbid ADHD or when the cognitive abilities of the ASD group and the control group were comparable. This meta-analysis confirmed the presence of executive dysfunction in children and adolescents with HFASD. These deficits are not solely accounted for by the effect of comorbid ADHD and the general cognitive abilities. Our results support the executive dysfunction hypothesis and contribute to the clinical understanding and possible development of interventions to alleviate these deficits in children and adolescents with HFASD. En ligne : http://dx.doi.org/10.1002/aur.1723 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307 [article] Meta-analysis of neuropsychological measures of executive functioning in children and adolescents with high-functioning autism spectrum disorder [Texte imprimé et/ou numérique] / Chun Lun Eric LAI, Auteur ; Zoe LAU, Auteur ; Simon S. Y. LUI, Auteur ; Eugenia LOK, Auteur ; Venus TAM, Auteur ; Quinney CHAN, Auteur ; Koi Man CHENG, Auteur ; Siu Man LAM, Auteur ; Eric F. C. CHEUNG, Auteur . - p.911-939. Langues : Anglais (eng) in Autism Research > 10-5 (May 2017) . - p.911-939 Mots-clés : executive function  high-functioning autism spectrum disorder  Asperger's syndrome  meta-analysis Index. décimale : PER Périodiques Résumé : Existing literature on the profile of executive dysfunction in autism spectrum disorder showed inconsistent results. Age, comorbid attention-deficit/hyperactivity disorder (ADHD) and cognitive abilities appeared to play a role in confounding the picture. Previous meta-analyses have focused on a few components of executive functions. This meta-analysis attempted to delineate the profile of deficit in several components of executive functioning in children and adolescents with high-functioning autism spectrum disorder (HFASD). Ninety-eight English published case-control studies comparing children and adolescents with HFASD with typically developing controls using well-known neuropsychological measures to assess executive functions were included. Results showed that children and adolescents with HFASD were moderately impaired in verbal working memory (g?=?0.67), spatial working memory (g?=?0.58), flexibility (g?=?0.59), planning (g?=?0.62), and generativity (g?=?0.60) except for inhibition (g?=?0.41). Subgroup analysis showed that impairments were still significant for flexibility (g?=?0.57–0.61), generativity (g?=?0.52–0.68), and working memory (g?=?0.49–0.56) in a sample of autism spectrum disorder (ASD) subjects without comorbid ADHD or when the cognitive abilities of the ASD group and the control group were comparable. This meta-analysis confirmed the presence of executive dysfunction in children and adolescents with HFASD. These deficits are not solely accounted for by the effect of comorbid ADHD and the general cognitive abilities. Our results support the executive dysfunction hypothesis and contribute to the clinical understanding and possible development of interventions to alleviate these deficits in children and adolescents with HFASD. En ligne : http://dx.doi.org/10.1002/aur.1723 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307

Neural Correlates of Audiovisual Temporal Binding Window in Individuals With Schizotypal and Autistic Traits: Evidence From Resting-State Functional Connectivity / Han-Yu ZHOU in Autism Research, 14-4 (April 2021)  

Public ISBD [article]  inAutism Research > 14-4 (April 2021) . - p.668-680 Titre : Neural Correlates of Audiovisual Temporal Binding Window in Individuals With Schizotypal and Autistic Traits: Evidence From Resting-State Functional Connectivity Type de document : Texte imprimé et/ou numérique Auteurs : Han-Yu ZHOU, Auteur ; Yong-Ming WANG, Auteur ; Rui-Ting ZHANG, Auteur ; Eric F. C. CHEUNG, Auteur ; Christos PANTELIS, Auteur ; Raymond C. K. CHAN, Auteur Article en page(s) : p.668-680 Langues : Anglais (eng) Mots-clés : audiovisual  autistic traits  resting-state functional connectivity  schizotypal traits  temporal binding window Index. décimale : PER Périodiques Résumé : Temporal proximity is an important clue for multisensory integration. Previous evidence indicates that individuals with autism and schizophrenia are more likely to integrate multisensory inputs over a longer temporal binding window (TBW). However, whether such deficits in audiovisual temporal integration extend to subclinical populations with high schizotypal and autistic traits are unclear. Using audiovisual simultaneity judgment (SJ) tasks for nonspeech and speech stimuli, our results suggested that the width of the audiovisual TBW was not significantly correlated with self-reported schizotypal and autistic traits in a group of young adults. Functional magnetic resonance imaging (fMRI) resting-state activity was also acquired to explore the neural correlates underlying inter-individual variability of TBW width. Across the entire sample, stronger resting-state functional connectivity (rsFC) between the left superior temporal cortex and the left precuneus, and weaker rsFC between the left cerebellum and the right dorsal lateral prefrontal cortex were correlated with a narrower TBW for speech stimuli. Meanwhile, stronger rsFC between the left anterior superior temporal gyrus and the right inferior temporal gyrus was correlated with a wider audiovisual TBW for non-speech stimuli. The TBW-related rsFC was not affected by levels of subclinical traits. In conclusion, this study indicates that audiovisual temporal processing may not be affected by autistic and schizotypal traits and rsFC between brain regions responding to multisensory information and timing may account for the inter-individual difference in TBW width. LAY SUMMARY: Individuals with ASD and schizophrenia are more likely to perceive asynchronous auditory and visual events as occurring simultaneously even if they are well separated in time. We investigated whether similar difficulties in audiovisual temporal processing were present in subclinical populations with high autistic and schizotypal traits. We found that the ability to detect audiovisual asynchrony was not affected by different levels of autistic and schizotypal traits. We also found that connectivity of some brain regions engaging in multisensory and timing tasks might explain an individual's tendency to bind multisensory information within a wide or narrow time window. Autism Res 2021, 14: 668-680. © 2020 International Society for Autism Research and Wiley Periodicals LLC. En ligne : http://dx.doi.org/10.1002/aur.2456 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=443 [article] Neural Correlates of Audiovisual Temporal Binding Window in Individuals With Schizotypal and Autistic Traits: Evidence From Resting-State Functional Connectivity [Texte imprimé et/ou numérique] / Han-Yu ZHOU, Auteur ; Yong-Ming WANG, Auteur ; Rui-Ting ZHANG, Auteur ; Eric F. C. CHEUNG, Auteur ; Christos PANTELIS, Auteur ; Raymond C. K. CHAN, Auteur . - p.668-680. Langues : Anglais (eng) in Autism Research > 14-4 (April 2021) . - p.668-680 Mots-clés : audiovisual  autistic traits  resting-state functional connectivity  schizotypal traits  temporal binding window Index. décimale : PER Périodiques Résumé : Temporal proximity is an important clue for multisensory integration. Previous evidence indicates that individuals with autism and schizophrenia are more likely to integrate multisensory inputs over a longer temporal binding window (TBW). However, whether such deficits in audiovisual temporal integration extend to subclinical populations with high schizotypal and autistic traits are unclear. Using audiovisual simultaneity judgment (SJ) tasks for nonspeech and speech stimuli, our results suggested that the width of the audiovisual TBW was not significantly correlated with self-reported schizotypal and autistic traits in a group of young adults. Functional magnetic resonance imaging (fMRI) resting-state activity was also acquired to explore the neural correlates underlying inter-individual variability of TBW width. Across the entire sample, stronger resting-state functional connectivity (rsFC) between the left superior temporal cortex and the left precuneus, and weaker rsFC between the left cerebellum and the right dorsal lateral prefrontal cortex were correlated with a narrower TBW for speech stimuli. Meanwhile, stronger rsFC between the left anterior superior temporal gyrus and the right inferior temporal gyrus was correlated with a wider audiovisual TBW for non-speech stimuli. The TBW-related rsFC was not affected by levels of subclinical traits. In conclusion, this study indicates that audiovisual temporal processing may not be affected by autistic and schizotypal traits and rsFC between brain regions responding to multisensory information and timing may account for the inter-individual difference in TBW width. LAY SUMMARY: Individuals with ASD and schizophrenia are more likely to perceive asynchronous auditory and visual events as occurring simultaneously even if they are well separated in time. We investigated whether similar difficulties in audiovisual temporal processing were present in subclinical populations with high autistic and schizotypal traits. We found that the ability to detect audiovisual asynchrony was not affected by different levels of autistic and schizotypal traits. We also found that connectivity of some brain regions engaging in multisensory and timing tasks might explain an individual's tendency to bind multisensory information within a wide or narrow time window. Autism Res 2021, 14: 668-680. © 2020 International Society for Autism Research and Wiley Periodicals LLC. En ligne : http://dx.doi.org/10.1002/aur.2456 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=443

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