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Auteur Sepideh SAROUKHANI |
Documents disponibles écrits par cet auteur (5)
Faire une suggestion Affiner la rechercheInteraction of Blood Manganese Concentrations with GSTT1 in Relation to Autism Spectrum Disorder in Jamaican Children / M. H. RAHBAR in Journal of Autism and Developmental Disorders, 51-6 (June 2021)
Titre : Interactive associations of eczema with glutathione S-transferase genes in relation to autism spectrum disorder and its severity in Jamaican children Type de document : Texte imprimé et/ou numérique Auteurs : Sepideh SAROUKHANI, Auteur ; Maureen SAMMS-VAUGHAN, Auteur ; Jan BRESSLER, Auteur ; MinJae LEE, Auteur ; Courtney BYRD-WILLIAMS, Auteur ; Manouchehr HESSABI, Auteur ; Megan L. GROVE, Auteur ; Sydonnie SHAKESPEARE-PELLINGTON, Auteur ; Katherine A. LOVELAND, Auteur ; Mohammad H. RAHBAR, Auteur Article en page(s) : 102183 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Eczema Glutathione S-transferase Oxidative stress Interaction Comorbidity Index. décimale : PER Périodiques Résumé : Background Comorbidity of eczema withith autism spectrum disorder (ASD) is increasing. We investigated the associations of eczema and its possible interaction with polymorphisms in glutathione S-transferase (GST) genes in relation to ASD and ASD severity. Method Using data from 344 1:1 age- and sex-matched ASD cases and typically developing controls, we assessed additive and interactive associations of eczema with GST genes in relation to ASD by applying conditional logistic regression models, and in relation to ASD severity in ASD cases as measured by the Autism Diagnostic Observation Schedule-2nd Edition (ADOS-2) total and domain-specific comparison scores (CSs) by fitting general linear models. Results After adjusting for child?s age and history of breastfeeding, eczema had no additive association with ASD [Matched Odds ratio (MOR) and 95 % Confidence Intervals (CI): 1.04 (0.76, 1.41), P = 0.82] or ASD severity (all P > 0.20). Using a recessive genetic model, eczema was significantly associated with ASD only among children with the Val/Val genotype for the GSTP1 Ile105Val polymorphism [MOR (95 % CI) = 2.04 (1.02, 4.08), P = 0.04, P for interaction = 0.03]. In addition, among ASD cases with the GSTM1 DD genotype, those with eczema had a marginally significant higher mean ADOS-2 Social Affect CS than those without eczema (7.3 vs. 6.8, P = 0.08, P for interaction = 0.09). Conclusion Our findings suggest children with certain genotypes for GST genes may be more susceptible for comorbidity of eczema and ASD, which is consistent with the role of GST genes in both conditions. En ligne : https://doi.org/10.1016/j.rasd.2023.102183 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508
in Research in Autism Spectrum Disorders > 105 (July 2023) . - 102183[article] Interactive associations of eczema with glutathione S-transferase genes in relation to autism spectrum disorder and its severity in Jamaican children [Texte imprimé et/ou numérique] / Sepideh SAROUKHANI, Auteur ; Maureen SAMMS-VAUGHAN, Auteur ; Jan BRESSLER, Auteur ; MinJae LEE, Auteur ; Courtney BYRD-WILLIAMS, Auteur ; Manouchehr HESSABI, Auteur ; Megan L. GROVE, Auteur ; Sydonnie SHAKESPEARE-PELLINGTON, Auteur ; Katherine A. LOVELAND, Auteur ; Mohammad H. RAHBAR, Auteur . - 102183.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 105 (July 2023) . - 102183
Mots-clés : Autism spectrum disorder Eczema Glutathione S-transferase Oxidative stress Interaction Comorbidity Index. décimale : PER Périodiques Résumé : Background Comorbidity of eczema withith autism spectrum disorder (ASD) is increasing. We investigated the associations of eczema and its possible interaction with polymorphisms in glutathione S-transferase (GST) genes in relation to ASD and ASD severity. Method Using data from 344 1:1 age- and sex-matched ASD cases and typically developing controls, we assessed additive and interactive associations of eczema with GST genes in relation to ASD by applying conditional logistic regression models, and in relation to ASD severity in ASD cases as measured by the Autism Diagnostic Observation Schedule-2nd Edition (ADOS-2) total and domain-specific comparison scores (CSs) by fitting general linear models. Results After adjusting for child?s age and history of breastfeeding, eczema had no additive association with ASD [Matched Odds ratio (MOR) and 95 % Confidence Intervals (CI): 1.04 (0.76, 1.41), P = 0.82] or ASD severity (all P > 0.20). Using a recessive genetic model, eczema was significantly associated with ASD only among children with the Val/Val genotype for the GSTP1 Ile105Val polymorphism [MOR (95 % CI) = 2.04 (1.02, 4.08), P = 0.04, P for interaction = 0.03]. In addition, among ASD cases with the GSTM1 DD genotype, those with eczema had a marginally significant higher mean ADOS-2 Social Affect CS than those without eczema (7.3 vs. 6.8, P = 0.08, P for interaction = 0.09). Conclusion Our findings suggest children with certain genotypes for GST genes may be more susceptible for comorbidity of eczema and ASD, which is consistent with the role of GST genes in both conditions. En ligne : https://doi.org/10.1016/j.rasd.2023.102183 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508
Titre : Perinatal Factors Associated with Autism Spectrum Disorder in Jamaican Children Type de document : Texte imprimé et/ou numérique Auteurs : Sepideh SAROUKHANI, Auteur ; Maureen SAMMS-VAUGHAN, Auteur ; MinJae LEE, Auteur ; MacKinsey A. BACH, Auteur ; Jan BRESSLER, Auteur ; Manouchehr HESSABI, Auteur ; Megan L. GROVE, Auteur ; Sydonnie SHAKESPEARE-PELLINGTON, Auteur ; Katherine A. LOVELAND, Auteur ; Mohammad H RAHBAR, Auteur Article en page(s) : p.3341-3357 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Cesarean delivery Jamaica Low birth weight Preterm birth interest. Maureen Samms-Vaughan declares that she has no conflict of interest. MinJae Lee declares that she has no conflict of interest. MacKinsey A. Bach declares that she has no conflict of interest. Jan Bressler declares that she has no conflict of interest. Manouchehr Hessabi declares that he has no conflict of interest. Megan L. Grove declares that she has no conflict of interest. Sydonnie Shakespeare-Pellington declares that she has no conflict of interest. Katherine A. Loveland declares that she has no conflict of interest. Mohammad H. Rahbar declares that he has no conflict of interest. Index. décimale : PER Périodiques Résumé : Mode of delivery, preterm birth, and low birth weight (LBW) are hypothesized to be associated with autism spectrum disorder (ASD) in the offspring. Using data from 343 ASD cases (2-8 years) and their age- and sex-matched typically developing controls in Jamaica we investigated these hypotheses. Our statistical analyses revealed that the parish of residence could modify the association between cesarean delivery and ASD, with a difference found in this relationship in Kingston parish [matched odds ratio (MOR) (95% confidence interval (CI)) 2.30 (1.17-4.53)] and other parishes [MOR (95% CI) 0.87 (0.48-1.59)]. Although the associations of LBW and preterm birth with ASD were not significant, we observed a significant interaction between LBW and the household socioeconomic status. These findings require replication. En ligne : http://dx.doi.org/10.1007/s10803-019-04229-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430
in Journal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3341-3357[article] Perinatal Factors Associated with Autism Spectrum Disorder in Jamaican Children [Texte imprimé et/ou numérique] / Sepideh SAROUKHANI, Auteur ; Maureen SAMMS-VAUGHAN, Auteur ; MinJae LEE, Auteur ; MacKinsey A. BACH, Auteur ; Jan BRESSLER, Auteur ; Manouchehr HESSABI, Auteur ; Megan L. GROVE, Auteur ; Sydonnie SHAKESPEARE-PELLINGTON, Auteur ; Katherine A. LOVELAND, Auteur ; Mohammad H RAHBAR, Auteur . - p.3341-3357.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3341-3357
Mots-clés : Autism spectrum disorder Cesarean delivery Jamaica Low birth weight Preterm birth interest. Maureen Samms-Vaughan declares that she has no conflict of interest. MinJae Lee declares that she has no conflict of interest. MacKinsey A. Bach declares that she has no conflict of interest. Jan Bressler declares that she has no conflict of interest. Manouchehr Hessabi declares that he has no conflict of interest. Megan L. Grove declares that she has no conflict of interest. Sydonnie Shakespeare-Pellington declares that she has no conflict of interest. Katherine A. Loveland declares that she has no conflict of interest. Mohammad H. Rahbar declares that he has no conflict of interest. Index. décimale : PER Périodiques Résumé : Mode of delivery, preterm birth, and low birth weight (LBW) are hypothesized to be associated with autism spectrum disorder (ASD) in the offspring. Using data from 343 ASD cases (2-8 years) and their age- and sex-matched typically developing controls in Jamaica we investigated these hypotheses. Our statistical analyses revealed that the parish of residence could modify the association between cesarean delivery and ASD, with a difference found in this relationship in Kingston parish [matched odds ratio (MOR) (95% confidence interval (CI)) 2.30 (1.17-4.53)] and other parishes [MOR (95% CI) 0.87 (0.48-1.59)]. Although the associations of LBW and preterm birth with ASD were not significant, we observed a significant interaction between LBW and the household socioeconomic status. These findings require replication. En ligne : http://dx.doi.org/10.1007/s10803-019-04229-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430
Titre : Severity of Child Autistic Symptoms and Parenting Stress in Mothers of Children with Autism Spectrum Disorder in Japan and USA: Cross-Cultural Differences Type de document : Texte imprimé et/ou numérique Auteurs : Noriko PORTER, Auteur ; Katherine A. LOVELAND, Auteur ; Sepideh SAROUKHANI, Auteur ; Yana POSEY, Auteur ; Kana MORIMOTO, Auteur ; Mohammad H. RAHBAR, Auteur Article en page(s) : 7089053 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The purpose of this study was to compare the relationship between parenting stress and autistic symptom severity in the U.S. and Japan. Fifty-two U.S. and 51 Japanese mothers of children aged 2-12 with autism completed measures of parenting stress and child characteristics, including the parenting stress index (PSI), the social communication questionnaire (SCQ), and social responsiveness scale-2 (SRS-2). There was a nonlinear relationship between the child's autistic symptom severity and parenting stress in both countries. We also found some cultural differences: in the parent domain, the relationships between children's SCQ scores and PSI scores differed significantly between the U.S. and Japan. Our findings suggest that autistic severity symptom scores may reflect cross-cultural differences in parenting beliefs, views toward autism, and response styles for evaluating children's behavior. The findings also suggest that parents need support regardless of the child's autism severity, including those with mild to moderate symptoms. Expanding on this line of research and understanding cultural influences on parenting stress may help service providers and agencies offer more culturally sensitive services, parent-education courses, and intervention programs. En ligne : https://doi.org/10.1155/2022/7089053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=491
in Autism Research and Treatment > 2022 (2022) . - 7089053[article] Severity of Child Autistic Symptoms and Parenting Stress in Mothers of Children with Autism Spectrum Disorder in Japan and USA: Cross-Cultural Differences [Texte imprimé et/ou numérique] / Noriko PORTER, Auteur ; Katherine A. LOVELAND, Auteur ; Sepideh SAROUKHANI, Auteur ; Yana POSEY, Auteur ; Kana MORIMOTO, Auteur ; Mohammad H. RAHBAR, Auteur . - 7089053.
Langues : Anglais (eng)
in Autism Research and Treatment > 2022 (2022) . - 7089053
Index. décimale : PER Périodiques Résumé : The purpose of this study was to compare the relationship between parenting stress and autistic symptom severity in the U.S. and Japan. Fifty-two U.S. and 51 Japanese mothers of children aged 2-12 with autism completed measures of parenting stress and child characteristics, including the parenting stress index (PSI), the social communication questionnaire (SCQ), and social responsiveness scale-2 (SRS-2). There was a nonlinear relationship between the child's autistic symptom severity and parenting stress in both countries. We also found some cultural differences: in the parent domain, the relationships between children's SCQ scores and PSI scores differed significantly between the U.S. and Japan. Our findings suggest that autistic severity symptom scores may reflect cross-cultural differences in parenting beliefs, views toward autism, and response styles for evaluating children's behavior. The findings also suggest that parents need support regardless of the child's autism severity, including those with mild to moderate symptoms. Expanding on this line of research and understanding cultural influences on parenting stress may help service providers and agencies offer more culturally sensitive services, parent-education courses, and intervention programs. En ligne : https://doi.org/10.1155/2022/7089053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=491
Titre : Severity of Child Autistic Symptoms and Parenting Stress in Mothers of Children with Autism Spectrum Disorder in Japan and USA: Cross-Cultural Differences Type de document : Texte imprimé et/ou numérique Auteurs : Noriko PORTER, Auteur ; Katherine A. LOVELAND, Auteur ; Sepideh SAROUKHANI, Auteur ; Yana POSEY, Auteur ; Kana MORIMOTO, Auteur ; Mohammad H. RAHBAR, Auteur Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The purpose of this study was to compare the relationship between parenting stress and autistic symptom severity in the U.S. and Japan. Fifty-two U.S. and 51 Japanese mothers of children aged 2?12 with autism completed measures of parenting stress and child characteristics, including the parenting stress index (PSI), the social communication questionnaire (SCQ), and social responsiveness scale-2 (SRS-2). There was a nonlinear relationship between the child's autistic symptom severity and parenting stress in both countries. We also found some cultural differences: in the parent domain, the relationships between children?s SCQ scores and PSI scores differed significantly between the U.S. and Japan. Our findings suggest that autistic severity symptom scores may reflect cross-cultural differences in parenting beliefs, views toward autism, and response styles for evaluating children?s behavior. The findings also suggest that parents need support regardless of the child?s autism severity, including those with mild to moderate symptoms. Expanding on this line of research and understanding cultural influences on parenting stress may help service providers and agencies offer more culturally sensitive services, parent-education courses, and intervention programs. En ligne : https://doi.org/10.1155/2022/7089053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538
in Autism Research and Treatment > 2022 (2022)[article] Severity of Child Autistic Symptoms and Parenting Stress in Mothers of Children with Autism Spectrum Disorder in Japan and USA: Cross-Cultural Differences [Texte imprimé et/ou numérique] / Noriko PORTER, Auteur ; Katherine A. LOVELAND, Auteur ; Sepideh SAROUKHANI, Auteur ; Yana POSEY, Auteur ; Kana MORIMOTO, Auteur ; Mohammad H. RAHBAR, Auteur.
Langues : Anglais (eng)
in Autism Research and Treatment > 2022 (2022)
Index. décimale : PER Périodiques Résumé : The purpose of this study was to compare the relationship between parenting stress and autistic symptom severity in the U.S. and Japan. Fifty-two U.S. and 51 Japanese mothers of children aged 2?12 with autism completed measures of parenting stress and child characteristics, including the parenting stress index (PSI), the social communication questionnaire (SCQ), and social responsiveness scale-2 (SRS-2). There was a nonlinear relationship between the child's autistic symptom severity and parenting stress in both countries. We also found some cultural differences: in the parent domain, the relationships between children?s SCQ scores and PSI scores differed significantly between the U.S. and Japan. Our findings suggest that autistic severity symptom scores may reflect cross-cultural differences in parenting beliefs, views toward autism, and response styles for evaluating children?s behavior. The findings also suggest that parents need support regardless of the child?s autism severity, including those with mild to moderate symptoms. Expanding on this line of research and understanding cultural influences on parenting stress may help service providers and agencies offer more culturally sensitive services, parent-education courses, and intervention programs. En ligne : https://doi.org/10.1155/2022/7089053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538
