Common infectious morbidity and white blood cell count in middle childhood predict behavior problems in adolescence / Rachael J. BEER in Development and Psychopathology, 35-1 (February 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-1 (February 2023) . - p.301-313 Titre : Common infectious morbidity and white blood cell count in middle childhood predict behavior problems in adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Rachael J. BEER, Auteur ; Kallisse R. DENT, Auteur ; Sonia L. ROBINSON, Auteur ; Henry OLIVEROS, Auteur ; Mercedes MORA-PLAZAS, Auteur ; Constanza MARIN, Auteur ; Eduardo VILLAMOR, Auteur Article en page(s) : p.301-313 Langues : Anglais (eng) Mots-clés : anxious/depressed behavior  diarrheal disease  internalizing behavior  respiratory infection  somatic complaints Index. décimale : PER Périodiques Résumé : We examined the associations of middle childhood infectious morbidity and inflammatory biomarkers with adolescent internalizing and externalizing behavior problems. We recruited 1018 Colombian schoolchildren aged 5-12 years into a cohort. We quantified white blood cell (WBC) counts and C-reactive protein at enrollment and prospectively recorded incidence of gastrointestinal, respiratory, and fever-associated morbidity during the first follow-up year. After a median 6 years, we assessed adolescent internalizing and externalizing behavior problems using child behavior checklist (CBCL) and youth self-report (YSR) questionnaires. Behavior problem scores were compared over biomarker and morbidity categories using mean differences and 95% confidence intervals (CI) from multivariable linear regression. Compared with children without symptoms, CBCL internalizing problem scores were an adjusted 2.5 (95% CI: 0.1, 4.9; p = .04) and 3.1 (95% CI: 1.1, 5.2; p = .003) units higher among children with moderate diarrhea with vomiting and high cough with fever rates, respectively. High cough with fever and high fever rates were associated with increased CBCL somatic complaints and anxious/depressed scores, respectively. WBC >10,000/mm3 was associated with both internalizing problem and YSR withdrawn/depressed scores. There were no associations with externalizing behavior problems. Whether or not decreasing the burden of common infections results in improved neurobehavioral outcomes warrants further investigation. En ligne : https://doi.org/10.1017/S0954579421000675 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] Common infectious morbidity and white blood cell count in middle childhood predict behavior problems in adolescence [Texte imprimé et/ou numérique] / Rachael J. BEER, Auteur ; Kallisse R. DENT, Auteur ; Sonia L. ROBINSON, Auteur ; Henry OLIVEROS, Auteur ; Mercedes MORA-PLAZAS, Auteur ; Constanza MARIN, Auteur ; Eduardo VILLAMOR, Auteur . - p.301-313. Langues : Anglais (eng) in Development and Psychopathology > 35-1 (February 2023) . - p.301-313 Mots-clés : anxious/depressed behavior  diarrheal disease  internalizing behavior  respiratory infection  somatic complaints Index. décimale : PER Périodiques Résumé : We examined the associations of middle childhood infectious morbidity and inflammatory biomarkers with adolescent internalizing and externalizing behavior problems. We recruited 1018 Colombian schoolchildren aged 5-12 years into a cohort. We quantified white blood cell (WBC) counts and C-reactive protein at enrollment and prospectively recorded incidence of gastrointestinal, respiratory, and fever-associated morbidity during the first follow-up year. After a median 6 years, we assessed adolescent internalizing and externalizing behavior problems using child behavior checklist (CBCL) and youth self-report (YSR) questionnaires. Behavior problem scores were compared over biomarker and morbidity categories using mean differences and 95% confidence intervals (CI) from multivariable linear regression. Compared with children without symptoms, CBCL internalizing problem scores were an adjusted 2.5 (95% CI: 0.1, 4.9; p = .04) and 3.1 (95% CI: 1.1, 5.2; p = .003) units higher among children with moderate diarrhea with vomiting and high cough with fever rates, respectively. High cough with fever and high fever rates were associated with increased CBCL somatic complaints and anxious/depressed scores, respectively. WBC >10,000/mm3 was associated with both internalizing problem and YSR withdrawn/depressed scores. There were no associations with externalizing behavior problems. Whether or not decreasing the burden of common infections results in improved neurobehavioral outcomes warrants further investigation. En ligne : https://doi.org/10.1017/S0954579421000675 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

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