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Détail de l'auteur
Auteur Douglas A. GRANGER |
Documents disponibles écrits par cet auteur (9)



Allostasis and allostatic load in the context of poverty in early childhood / Clancy BLAIR in Development and Psychopathology, 23-3 (August 2011)
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Titre : Allostasis and allostatic load in the context of poverty in early childhood Type de document : Texte imprimé et/ou numérique Auteurs : Clancy BLAIR, Auteur ; C. Cybele RAVER, Auteur ; Douglas A. GRANGER, Auteur ; W. Roger MILLS-KOONCE, Auteur ; Leah C. HIBEL, Auteur ; THE FAMILY LIFE PROJECT KEY INVESTIGATORS, Auteur Année de publication : 2011 Article en page(s) : p.845-857 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : This paper examined the relation of early environmental adversity associated with poverty to child resting or basal level of cortisol in a prospective longitudinal sample of 1135 children seen at 7, 15, 24, 35, and 48 months of age. We found main effects for poor housing quality, African American ethnicity, and low positive caregiving behavior in which each was uniquely associated with an overall higher level of cortisol from age 7 to 48 months. We also found that two aspects of the early environment in the context of poverty, adult exits from the home and perceived economic insufficiency, were related to salivary cortisol in a time-dependent manner. The effect for the first of these, exits from the home, was consistent with the principle of allostatic load in which the effects of adversity on stress physiology accumulate over time. The effect for perceived economic insufficiency was one in which insufficiency was associated with higher levels of cortisol in infancy but with a typical but steeper decline in cortisol with age at subsequent time points. En ligne : http://dx.doi.org/10.1017/S0954579411000344 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132
in Development and Psychopathology > 23-3 (August 2011) . - p.845-857[article] Allostasis and allostatic load in the context of poverty in early childhood [Texte imprimé et/ou numérique] / Clancy BLAIR, Auteur ; C. Cybele RAVER, Auteur ; Douglas A. GRANGER, Auteur ; W. Roger MILLS-KOONCE, Auteur ; Leah C. HIBEL, Auteur ; THE FAMILY LIFE PROJECT KEY INVESTIGATORS, Auteur . - 2011 . - p.845-857.
Langues : Anglais (eng)
in Development and Psychopathology > 23-3 (August 2011) . - p.845-857
Index. décimale : PER Périodiques Résumé : This paper examined the relation of early environmental adversity associated with poverty to child resting or basal level of cortisol in a prospective longitudinal sample of 1135 children seen at 7, 15, 24, 35, and 48 months of age. We found main effects for poor housing quality, African American ethnicity, and low positive caregiving behavior in which each was uniquely associated with an overall higher level of cortisol from age 7 to 48 months. We also found that two aspects of the early environment in the context of poverty, adult exits from the home and perceived economic insufficiency, were related to salivary cortisol in a time-dependent manner. The effect for the first of these, exits from the home, was consistent with the principle of allostatic load in which the effects of adversity on stress physiology accumulate over time. The effect for perceived economic insufficiency was one in which insufficiency was associated with higher levels of cortisol in infancy but with a typical but steeper decline in cortisol with age at subsequent time points. En ligne : http://dx.doi.org/10.1017/S0954579411000344 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132 Child behavior problems among cocaine-exposed toddlers: Indirect and interactive effects / Rina Das EIDEN in Development and Psychopathology, 23-2 (May 2011)
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Titre : Child behavior problems among cocaine-exposed toddlers: Indirect and interactive effects Type de document : Texte imprimé et/ou numérique Auteurs : Rina Das EIDEN, Auteur ; Douglas A. GRANGER, Auteur ; Pamela SCHUETZE, Auteur ; Yvette VEIRA, Auteur Année de publication : 2011 Article en page(s) : p.539-550 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : This study examined the role of maternal psychopathology and maternal warmth as mediators of the association between prenatal cocaine and other substance exposure and toddler behavior problems. It was also hypothesized that infant cortisol reactivity and environmental risk may moderate these associations. Participants were 220 caregiver–infant dyads (119 cocaine exposed, 101 not cocaine exposed; 49% boys). Mother–infant dyads were recruited at delivery with assessments at 4–8 weeks and 7, 13, and 18 months of child ages. Results yielded no direct associations between prenatal cocaine/other substance exposure and toddler behavior problems, but significant indirect associations between prenatal cigarette/alcohol exposure and toddler behavior problems at 18 months. With regard to moderation, results indicated an indirect association between prenatal cocaine exposure and toddler behavior problems via lower maternal warmth for children with higher, but not lower, cortisol reactivity at 7 months. Results suggest potential pathways to toddler behavior problems among children at high biological risk. En ligne : http://dx.doi.org/10.1017/S0954579411000058 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121
in Development and Psychopathology > 23-2 (May 2011) . - p.539-550[article] Child behavior problems among cocaine-exposed toddlers: Indirect and interactive effects [Texte imprimé et/ou numérique] / Rina Das EIDEN, Auteur ; Douglas A. GRANGER, Auteur ; Pamela SCHUETZE, Auteur ; Yvette VEIRA, Auteur . - 2011 . - p.539-550.
Langues : Anglais (eng)
in Development and Psychopathology > 23-2 (May 2011) . - p.539-550
Index. décimale : PER Périodiques Résumé : This study examined the role of maternal psychopathology and maternal warmth as mediators of the association between prenatal cocaine and other substance exposure and toddler behavior problems. It was also hypothesized that infant cortisol reactivity and environmental risk may moderate these associations. Participants were 220 caregiver–infant dyads (119 cocaine exposed, 101 not cocaine exposed; 49% boys). Mother–infant dyads were recruited at delivery with assessments at 4–8 weeks and 7, 13, and 18 months of child ages. Results yielded no direct associations between prenatal cocaine/other substance exposure and toddler behavior problems, but significant indirect associations between prenatal cigarette/alcohol exposure and toddler behavior problems at 18 months. With regard to moderation, results indicated an indirect association between prenatal cocaine exposure and toddler behavior problems via lower maternal warmth for children with higher, but not lower, cortisol reactivity at 7 months. Results suggest potential pathways to toddler behavior problems among children at high biological risk. En ligne : http://dx.doi.org/10.1017/S0954579411000058 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 Daytime Secretion of Salivary Cortisol and Alpha-Amylase in Preschool-Aged Children with Autism and Typically Developing Children / Sharon A. KIDD in Journal of Autism and Developmental Disorders, 42-12 (December 2012)
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Titre : Daytime Secretion of Salivary Cortisol and Alpha-Amylase in Preschool-Aged Children with Autism and Typically Developing Children Type de document : Texte imprimé et/ou numérique Auteurs : Sharon A. KIDD, Auteur ; Blythe A. CORBETT, Auteur ; Douglas A. GRANGER, Auteur ; W. Thomas BOYCE, Auteur ; Thomas F. ANDERS, Auteur ; Ira B. TAGER, Auteur Année de publication : 2012 Article en page(s) : p.2648-2658 Langues : Anglais (eng) Mots-clés : Autism Children Salivary cortisol Salivary alpha-amylase Diurnal Variability Index. décimale : PER Périodiques Résumé : We examined daytime salivary cortisol and salivary alpha-amylase (sAA) secretion levels and variability in preschool-aged children with autism (AUT) and typically developing children (TYP). Fifty-two subjects (26 AUT and 26 TYP) were enrolled. Salivary samples were obtained at waking, midday, and bedtime on two consecutive days at three phases (baseline, 3 months later, 6 months later). There were modest increases in waking cortisol and sAA levels in AUT relative to TYP, but the increases were not statistically significant. Important differences were observed in cortisol and sAA variability between AUT and TYP. There was also a graded response among AUT by functional status' cortisol and sAA secretion levels were higher when IQ was lower. En ligne : http://dx.doi.org/10.1007/s10803-012-1522-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=184
in Journal of Autism and Developmental Disorders > 42-12 (December 2012) . - p.2648-2658[article] Daytime Secretion of Salivary Cortisol and Alpha-Amylase in Preschool-Aged Children with Autism and Typically Developing Children [Texte imprimé et/ou numérique] / Sharon A. KIDD, Auteur ; Blythe A. CORBETT, Auteur ; Douglas A. GRANGER, Auteur ; W. Thomas BOYCE, Auteur ; Thomas F. ANDERS, Auteur ; Ira B. TAGER, Auteur . - 2012 . - p.2648-2658.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-12 (December 2012) . - p.2648-2658
Mots-clés : Autism Children Salivary cortisol Salivary alpha-amylase Diurnal Variability Index. décimale : PER Périodiques Résumé : We examined daytime salivary cortisol and salivary alpha-amylase (sAA) secretion levels and variability in preschool-aged children with autism (AUT) and typically developing children (TYP). Fifty-two subjects (26 AUT and 26 TYP) were enrolled. Salivary samples were obtained at waking, midday, and bedtime on two consecutive days at three phases (baseline, 3 months later, 6 months later). There were modest increases in waking cortisol and sAA levels in AUT relative to TYP, but the increases were not statistically significant. Important differences were observed in cortisol and sAA variability between AUT and TYP. There was also a graded response among AUT by functional status' cortisol and sAA secretion levels were higher when IQ was lower. En ligne : http://dx.doi.org/10.1007/s10803-012-1522-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=184 Early adversity and internalizing symptoms in adolescence: Mediation by individual differences in latent trait cortisol / Catherine B. STROUD in Development and Psychopathology, 31-2 (May 2019)
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Titre : Early adversity and internalizing symptoms in adolescence: Mediation by individual differences in latent trait cortisol Type de document : Texte imprimé et/ou numérique Auteurs : Catherine B. STROUD, Auteur ; Frances S. CHEN, Auteur ; Leah D. DOANE, Auteur ; Douglas A. GRANGER, Auteur Article en page(s) : p.509-524 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Research suggests that early adversity places individuals at risk for psychopathology across the life span. Guided by concepts of allostasis and allostatic load, the present study examined whether early adversity contributes to the development of subsequent internalizing symptoms through its association with traitlike individual differences in hypothalamic–pituitary–adrenal axis regulation. Early adolescent girls (n = 113; M age = 12.30 years) provided saliva samples at waking, 30 min postwaking, and bedtime over 3 days (later assayed for cortisol). Objective contextual stress interviews with adolescents and their mothers were used to assess the accumulation of nine types of early adversity within the family environment. Greater early adversity predicted subsequent increases in internalizing symptoms through lower levels of latent trait cortisol. Traitlike individual differences in hypothalamic–pituitary–adrenal axis activity may be among the mechanisms through which early adversity confers risk for the development of psychopathology. En ligne : http://dx.doi.org/10.1017/S0954579418000044 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=393
in Development and Psychopathology > 31-2 (May 2019) . - p.509-524[article] Early adversity and internalizing symptoms in adolescence: Mediation by individual differences in latent trait cortisol [Texte imprimé et/ou numérique] / Catherine B. STROUD, Auteur ; Frances S. CHEN, Auteur ; Leah D. DOANE, Auteur ; Douglas A. GRANGER, Auteur . - p.509-524.
Langues : Anglais (eng)
in Development and Psychopathology > 31-2 (May 2019) . - p.509-524
Index. décimale : PER Périodiques Résumé : Research suggests that early adversity places individuals at risk for psychopathology across the life span. Guided by concepts of allostasis and allostatic load, the present study examined whether early adversity contributes to the development of subsequent internalizing symptoms through its association with traitlike individual differences in hypothalamic–pituitary–adrenal axis regulation. Early adolescent girls (n = 113; M age = 12.30 years) provided saliva samples at waking, 30 min postwaking, and bedtime over 3 days (later assayed for cortisol). Objective contextual stress interviews with adolescents and their mothers were used to assess the accumulation of nine types of early adversity within the family environment. Greater early adversity predicted subsequent increases in internalizing symptoms through lower levels of latent trait cortisol. Traitlike individual differences in hypothalamic–pituitary–adrenal axis activity may be among the mechanisms through which early adversity confers risk for the development of psychopathology. En ligne : http://dx.doi.org/10.1017/S0954579418000044 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=393 Greater fear reactivity and psychophysiological hyperactivity among infants with later conduct problems and callous-unemotional traits / William R. MILLS-KOONCE in Journal of Child Psychology and Psychiatry, 56-2 (February 2015)
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Titre : Greater fear reactivity and psychophysiological hyperactivity among infants with later conduct problems and callous-unemotional traits Type de document : Texte imprimé et/ou numérique Auteurs : William R. MILLS-KOONCE, Auteur ; Nicholas J. WAGNER, Auteur ; Michael T. WILLOUGHBY, Auteur ; Cynthia STIFTER, Auteur ; Clancy BLAIR, Auteur ; Douglas A. GRANGER, Auteur ; Investigators THE FAMILY LIFE PROJECT KEY, Auteur Article en page(s) : p.147-154 Langues : Anglais (eng) Mots-clés : Fearlessness psychobiology autonomic cortisol conduct problems callous-unemotional traits Index. décimale : PER Périodiques Résumé : Background Approximately one third of children who meet criteria for conduct problems (CP) are also characterized by elevated callous-unemotional (CU) traits. This subgroup is at elevated risk for more pervasive and extreme levels of later antisocial behavior and has been characterized by a fearlessness temperament and blunted stress psychophysiology at older ages. The objective of this study was to examine group differences in fear reactivity and stress psychophysiology in infancy among children classified as having CP with CU (CP + CU), CP without CU (CP only), or no CP in later childhood. Methods A birth cohort study (n = 1,292) was followed longitudinally from birth through first grade. Behavioral fear, baseline heart period (HP) and respiratory sinus arrhythmia (RSA), and pretask, 20-min posttask, and 40-min posttask salivary cortisol were assessed at 6 and 15 months of age around a fear challenge task. CP and CU were assessed by maternal report at first grade and children were classified into CP and CU groups if they scored in the upper 10th percentile of these ratings. Results No group differences were observed in children at 6 months of age. However, at 15 months of age children with later CP + CU displayed greater high-intensity fear behavior, higher pretask and overall cortisol levels, and lower levels of HP and RSA compared to children with CP only and children with no CP. Conclusions The discrepancy between the biobehavioral correlates of conduct problems with callous-unemotional traits in infancy and those reported from studies of older children and adults suggests that the etiology of this behavioral phenotype may be more complex than a simple genetic maturation model. En ligne : http://dx.doi.org/10.1111/jcpp.12289 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259
in Journal of Child Psychology and Psychiatry > 56-2 (February 2015) . - p.147-154[article] Greater fear reactivity and psychophysiological hyperactivity among infants with later conduct problems and callous-unemotional traits [Texte imprimé et/ou numérique] / William R. MILLS-KOONCE, Auteur ; Nicholas J. WAGNER, Auteur ; Michael T. WILLOUGHBY, Auteur ; Cynthia STIFTER, Auteur ; Clancy BLAIR, Auteur ; Douglas A. GRANGER, Auteur ; Investigators THE FAMILY LIFE PROJECT KEY, Auteur . - p.147-154.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-2 (February 2015) . - p.147-154
Mots-clés : Fearlessness psychobiology autonomic cortisol conduct problems callous-unemotional traits Index. décimale : PER Périodiques Résumé : Background Approximately one third of children who meet criteria for conduct problems (CP) are also characterized by elevated callous-unemotional (CU) traits. This subgroup is at elevated risk for more pervasive and extreme levels of later antisocial behavior and has been characterized by a fearlessness temperament and blunted stress psychophysiology at older ages. The objective of this study was to examine group differences in fear reactivity and stress psychophysiology in infancy among children classified as having CP with CU (CP + CU), CP without CU (CP only), or no CP in later childhood. Methods A birth cohort study (n = 1,292) was followed longitudinally from birth through first grade. Behavioral fear, baseline heart period (HP) and respiratory sinus arrhythmia (RSA), and pretask, 20-min posttask, and 40-min posttask salivary cortisol were assessed at 6 and 15 months of age around a fear challenge task. CP and CU were assessed by maternal report at first grade and children were classified into CP and CU groups if they scored in the upper 10th percentile of these ratings. Results No group differences were observed in children at 6 months of age. However, at 15 months of age children with later CP + CU displayed greater high-intensity fear behavior, higher pretask and overall cortisol levels, and lower levels of HP and RSA compared to children with CP only and children with no CP. Conclusions The discrepancy between the biobehavioral correlates of conduct problems with callous-unemotional traits in infancy and those reported from studies of older children and adults suggests that the etiology of this behavioral phenotype may be more complex than a simple genetic maturation model. En ligne : http://dx.doi.org/10.1111/jcpp.12289 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 Maternal sensitivity and adrenocortical functioning across infancy and toddlerhood: Physiological adaptation to context? / Daniel BERRY in Development and Psychopathology, 29-1 (February 2017)
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PermalinkMaternal sensitivity buffers the adrenocortical implications of intimate partner violence exposure during early childhood / Leah C. HIBEL in Development and Psychopathology, 23-2 (May 2011)
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PermalinkStress response and the adolescent transition: Performance versus peer rejection stressors / Laura R. STROUD in Development and Psychopathology, 21-1 (January 2009)
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PermalinkTrajectories of maternal depressive symptoms over her child's life span: Relation to adrenocortical, cardiovascular, and emotional functioning in children / Brooks B. GUMP in Development and Psychopathology, 21-1 (January 2009)
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