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Détail de l'auteur
Auteur Mitul A. MEHTA |
Documents disponibles écrits par cet auteur (2)
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Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: The English and Romanian Adoptees Study Pilot / Mitul A. MEHTA in Journal of Child Psychology and Psychiatry, 50-8 (August 2009)
[article]
Titre : Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: The English and Romanian Adoptees Study Pilot Type de document : Texte imprimé et/ou numérique Auteurs : Mitul A. MEHTA, Auteur ; Michael RUTTER, Auteur ; Emma COLVERT, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur ; Steve C.R. WILLIAMS, Auteur ; Nicole I. GOLEMBO, Auteur ; Chiara NOSARTI, Auteur ; Ashley MOTA, Auteur Année de publication : 2009 Article en page(s) : p.943-951 Langues : Anglais (eng) Mots-clés : Corpus-callosum hippocampus amygdala deprivation neurodevelopment institution-rearing adolescence brain-imaging brain-development Index. décimale : PER Périodiques Résumé : The adoption into the UK of children who have been reared in severely deprived conditions provides an opportunity to study possible association between very early negative experiences and subsequent brain development. This cross-sectional study was a pilot for a planned larger study quantifying the effects of early deprivation on later brain structure. We used magnetic resonance imaging (MRI) to measure the sizes of three key brain regions hypothesized to be sensitive to early adverse experiences. Our sample was a group of adoptee adolescents (N = 14) who had experienced severe early institutional deprivation in Romania and a group of non-institutionalised controls (N = 11). The total grey and white matter volumes were significantly smaller in the institutionalised group compared with a group of non-deprived, non-adopted UK controls. After correcting for difference in brain volume, the institutionalised group had greater amygdala volumes, especially on the right, but no differences were observed in hippocampal volume or corpus callosum mid-sagittal area. The left amygdala volume was also related to the time spent in institutions, with those experiencing longer periods of deprivation having a smaller left amygdala volume. These pilot findings highlight the need for future studies to confirm the sensitivity of the amygdala to early deprivation. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02084.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=787
in Journal of Child Psychology and Psychiatry > 50-8 (August 2009) . - p.943-951[article] Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: The English and Romanian Adoptees Study Pilot [Texte imprimé et/ou numérique] / Mitul A. MEHTA, Auteur ; Michael RUTTER, Auteur ; Emma COLVERT, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur ; Steve C.R. WILLIAMS, Auteur ; Nicole I. GOLEMBO, Auteur ; Chiara NOSARTI, Auteur ; Ashley MOTA, Auteur . - 2009 . - p.943-951.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 50-8 (August 2009) . - p.943-951
Mots-clés : Corpus-callosum hippocampus amygdala deprivation neurodevelopment institution-rearing adolescence brain-imaging brain-development Index. décimale : PER Périodiques Résumé : The adoption into the UK of children who have been reared in severely deprived conditions provides an opportunity to study possible association between very early negative experiences and subsequent brain development. This cross-sectional study was a pilot for a planned larger study quantifying the effects of early deprivation on later brain structure. We used magnetic resonance imaging (MRI) to measure the sizes of three key brain regions hypothesized to be sensitive to early adverse experiences. Our sample was a group of adoptee adolescents (N = 14) who had experienced severe early institutional deprivation in Romania and a group of non-institutionalised controls (N = 11). The total grey and white matter volumes were significantly smaller in the institutionalised group compared with a group of non-deprived, non-adopted UK controls. After correcting for difference in brain volume, the institutionalised group had greater amygdala volumes, especially on the right, but no differences were observed in hippocampal volume or corpus callosum mid-sagittal area. The left amygdala volume was also related to the time spent in institutions, with those experiencing longer periods of deprivation having a smaller left amygdala volume. These pilot findings highlight the need for future studies to confirm the sensitivity of the amygdala to early deprivation. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02084.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=787 Commentary: The only way is down. Augmented deactivation of the default mode network by increased catecholamine transmission – a general mechanism? Reflections on Liddle et al. (2011) / Mitul A. MEHTA in Journal of Child Psychology and Psychiatry, 52-7 (July 2011)
[article]
Titre : Commentary: The only way is down. Augmented deactivation of the default mode network by increased catecholamine transmission – a general mechanism? Reflections on Liddle et al. (2011) Type de document : Texte imprimé et/ou numérique Auteurs : Mitul A. MEHTA, Auteur Année de publication : 2011 Article en page(s) : p.772-773 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02401.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=126
in Journal of Child Psychology and Psychiatry > 52-7 (July 2011) . - p.772-773[article] Commentary: The only way is down. Augmented deactivation of the default mode network by increased catecholamine transmission – a general mechanism? Reflections on Liddle et al. (2011) [Texte imprimé et/ou numérique] / Mitul A. MEHTA, Auteur . - 2011 . - p.772-773.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 52-7 (July 2011) . - p.772-773
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02401.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=126