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Détail de l'auteur
Auteur Kimberly E. LANNI |
Documents disponibles écrits par cet auteur (2)
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Comparing biobehavioral profiles across two social stress paradigms in children with and without autism spectrum disorders / Blythe A. CORBETT in Molecular Autism, (November 2012)
[article]
Titre : Comparing biobehavioral profiles across two social stress paradigms in children with and without autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Blythe A. CORBETT, Auteur ; Clayton W. SCHUPP, Auteur ; Kimberly E. LANNI, Auteur Année de publication : 2012 Article en page(s) : 10 p. Langues : Anglais (eng) Mots-clés : Cortisol Autism Stress Novelty Peer Age Distribution Index. décimale : PER Périodiques Résumé : BACKGROUND:Autism spectrum disorders (ASD) are defined by impairment in reciprocal social interaction and flexible adaptation to the environment. This study compared physiological stress in children with and without ASD exposed to two social stress protocols. We hypothesized that the ASD group would show heightened initial and enduring cortisol levels to the social stressors, which would be moderated by age and intelligence.METHODS:Twenty-seven children with ASD and 32 with typical development (TYP) completed a standardized social-evaluative performance task and a validated paradigm of social play with peers. Physiological stress was measured by salivary cortisol at nine time points. Statistical approaches included repeated-measures linear mixed models and correlation analyses.RESULTS:The average cortisol level of both groups during initial exposure to social situations was significantly greater than baseline levels (ASD, P = 0.018; TYP, P = 0.006). Stress responsivity was significantly different between the groups; the TYP group showed a significant reduction in cortisol over time (P = 0.023), whereas the ASD group maintained an elevated cortisol level (P 0.05). The ASD group evidenced greater variability in between-group, within-group and intra-individual analyses. Age was a positive moderator of stress for the ASD group (P = 0.047), whereas IQ was a negative moderator for the TYP group (P = 0.061).CONCLUSIONS:Initial stress to novel social scenarios is idiosyncratic and predictive of subsequent exposure. Amidst significant variability in cortisol, children with ASD show enhanced and sustained social stress that increases with age. Developmental and cognitive factors differentially moderate stress in children with ASD and TYP, respectively. A model of neuroendocrine reactivity is proposed. En ligne : http://dx.doi.org/10.1186/2040-2392-3-13 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202
in Molecular Autism > (November 2012) . - 10 p.[article] Comparing biobehavioral profiles across two social stress paradigms in children with and without autism spectrum disorders [Texte imprimé et/ou numérique] / Blythe A. CORBETT, Auteur ; Clayton W. SCHUPP, Auteur ; Kimberly E. LANNI, Auteur . - 2012 . - 10 p.
Langues : Anglais (eng)
in Molecular Autism > (November 2012) . - 10 p.
Mots-clés : Cortisol Autism Stress Novelty Peer Age Distribution Index. décimale : PER Périodiques Résumé : BACKGROUND:Autism spectrum disorders (ASD) are defined by impairment in reciprocal social interaction and flexible adaptation to the environment. This study compared physiological stress in children with and without ASD exposed to two social stress protocols. We hypothesized that the ASD group would show heightened initial and enduring cortisol levels to the social stressors, which would be moderated by age and intelligence.METHODS:Twenty-seven children with ASD and 32 with typical development (TYP) completed a standardized social-evaluative performance task and a validated paradigm of social play with peers. Physiological stress was measured by salivary cortisol at nine time points. Statistical approaches included repeated-measures linear mixed models and correlation analyses.RESULTS:The average cortisol level of both groups during initial exposure to social situations was significantly greater than baseline levels (ASD, P = 0.018; TYP, P = 0.006). Stress responsivity was significantly different between the groups; the TYP group showed a significant reduction in cortisol over time (P = 0.023), whereas the ASD group maintained an elevated cortisol level (P 0.05). The ASD group evidenced greater variability in between-group, within-group and intra-individual analyses. Age was a positive moderator of stress for the ASD group (P = 0.047), whereas IQ was a negative moderator for the TYP group (P = 0.061).CONCLUSIONS:Initial stress to novel social scenarios is idiosyncratic and predictive of subsequent exposure. Amidst significant variability in cortisol, children with ASD show enhanced and sustained social stress that increases with age. Developmental and cognitive factors differentially moderate stress in children with ASD and TYP, respectively. A model of neuroendocrine reactivity is proposed. En ligne : http://dx.doi.org/10.1186/2040-2392-3-13 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202 Verbal ability, social stress, and anxiety in children with Autistic Disorder / Kimberly E. LANNI in Autism, 16-2 (March 2012)
[article]
Titre : Verbal ability, social stress, and anxiety in children with Autistic Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Kimberly E. LANNI, Auteur ; Clayton W. SCHUPP, Auteur ; David SIMON, Auteur ; Blythe A. CORBETT, Auteur Année de publication : 2012 Article en page(s) : p.123-138 Langues : Anglais (eng) Mots-clés : Autism cortisol stress anxiety Trier social stress test verbal ability Index. décimale : PER Périodiques Résumé : The aims of this study were to evaluate the physiological stress and anxiety responses in children with autism following completion of a standardized, social-evaluative stressor (Trier Social Stress Test-Child version), document the relationship between verbal ability, stress, and anxiety, and determine the association between stress and anxiety in children with autism and typical development. Results demonstrated the Trier Social Stress Test-Child version to be a benign stressor for children with autism. Lower verbal ability in children with autism did not predict salivary cortisol or anxiety responses. There was a lack of association between stress andanxiety for both groups, highlighting the importance of considering these terms as separate constructs. Clinical implications and the limited utility of the Trier Social Stress Test–Child version in evaluating psychosocial stress in autism are discussed. En ligne : http://dx.doi.org/10.1177/1362361311425916 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=155
in Autism > 16-2 (March 2012) . - p.123-138[article] Verbal ability, social stress, and anxiety in children with Autistic Disorder [Texte imprimé et/ou numérique] / Kimberly E. LANNI, Auteur ; Clayton W. SCHUPP, Auteur ; David SIMON, Auteur ; Blythe A. CORBETT, Auteur . - 2012 . - p.123-138.
Langues : Anglais (eng)
in Autism > 16-2 (March 2012) . - p.123-138
Mots-clés : Autism cortisol stress anxiety Trier social stress test verbal ability Index. décimale : PER Périodiques Résumé : The aims of this study were to evaluate the physiological stress and anxiety responses in children with autism following completion of a standardized, social-evaluative stressor (Trier Social Stress Test-Child version), document the relationship between verbal ability, stress, and anxiety, and determine the association between stress and anxiety in children with autism and typical development. Results demonstrated the Trier Social Stress Test-Child version to be a benign stressor for children with autism. Lower verbal ability in children with autism did not predict salivary cortisol or anxiety responses. There was a lack of association between stress andanxiety for both groups, highlighting the importance of considering these terms as separate constructs. Clinical implications and the limited utility of the Trier Social Stress Test–Child version in evaluating psychosocial stress in autism are discussed. En ligne : http://dx.doi.org/10.1177/1362361311425916 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=155