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Auteur Andreas WARNKE |
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Does intensive multimodal treatment for maternal ADHD improve the efficacy of parent training for children with ADHD? A randomized controlled multicenter trial / Thomas JANS in Journal of Child Psychology and Psychiatry, 56-12 (December 2015)
[article]
Titre : Does intensive multimodal treatment for maternal ADHD improve the efficacy of parent training for children with ADHD? A randomized controlled multicenter trial Type de document : Texte imprimé et/ou numérique Auteurs : Thomas JANS, Auteur ; Christian JACOB, Auteur ; Andreas WARNKE, Auteur ; Ulrike ZWANZGER, Auteur ; Silke GROß-LESCH, Auteur ; Swantje MATTHIES, Auteur ; Patricia BOREL, Auteur ; Klaus HENNIGHAUSEN, Auteur ; Barbara HAACK-DEES, Auteur ; Michael RÖSLER, Auteur ; Wolfgang RETZ, Auteur ; Alexander VON GONTARD, Auteur ; Susann HÄNIG, Auteur ; Esther SOBANSKI, Auteur ; Barbara ALM, Auteur ; Luise POUSTKA, Auteur ; Sarah HOHMANN, Auteur ; Michael COLLA, Auteur ; Laura GENTSCHOW, Auteur ; Charlotte JAITE, Auteur ; Viola KAPPEL, Auteur ; Katja BECKER, Auteur ; Martin HOLTMANN, Auteur ; Christine FREITAG, Auteur ; Erika GRAF, Auteur ; Gabriele IHORST, Auteur ; Alexandra PHILIPSEN, Auteur Article en page(s) : p.1298-1313 Langues : Anglais (eng) Mots-clés : Parental ADHD parent training dialectical behavioral therapy stimulant medication Index. décimale : PER Périodiques Résumé : Background This is the first randomized controlled multicenter trial to evaluate the effect of two treatments of maternal attention-deficit hyperactivity disorder (ADHD) on response to parent–child training targeting children's external psychopathology. Methods Mother–child dyads (n = 144; ADHD according to DSM-IV; children: 73.5% males, mean age 9.4 years) from five specialized university outpatient units in Germany were centrally randomized to multimodal maternal ADHD treatment [group psychotherapy plus open methylphenidate medication; treatment group (TG): n = 77] or to clinical management [supportive counseling without psychotherapy or psychopharmacotherapy; control group (CG): n = 67]. After 12 weeks, the maternal ADHD treatment was supplemented by individual parent–child training for all dyads. The primary outcome was a change in the children's externalizing symptom scores (investigator blinded to the treatment assignment) from baseline to the end of the parent–child training 6 months later. Maintenance therapy continued for another 6 months. An intention-to-treat analysis was performed within a linear regression model, controlling for baseline and center after multiple imputations of missing values. Results Exactly, 206 dyads were assessed for eligibility, 144 were randomized, and 143 were analyzed (TG: n = 77; CG: n = 66). After 6 months, no significant between-group differences were found in change scores for children's externalizing symptoms (adjusted mean TG-mean CG=1.1, 95% confidence interval ?0.5–2.7; p = .1854), although maternal psychopathology improved more in the TG. Children's externalizing symptom scores improved from a mean of 14.8 at baseline to 11.4 (TG) and 10.3 (CG) after 6 months and to 10.8 (TG) and 10.1 (CG) after 1 year. No severe harms related to study treatments were found, but adverse events were more frequent in TG mothers than in CG mothers. Conclusions The response in children's externalizing psychopathology did not differ between maternal treatment groups. However, multimodal treatment was associated with more improvement in maternal ADHD. Child and maternal treatment gains were stable (CCT-ISRCTN73911400). En ligne : http://dx.doi.org/10.1111/jcpp.12443 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273
in Journal of Child Psychology and Psychiatry > 56-12 (December 2015) . - p.1298-1313[article] Does intensive multimodal treatment for maternal ADHD improve the efficacy of parent training for children with ADHD? A randomized controlled multicenter trial [Texte imprimé et/ou numérique] / Thomas JANS, Auteur ; Christian JACOB, Auteur ; Andreas WARNKE, Auteur ; Ulrike ZWANZGER, Auteur ; Silke GROß-LESCH, Auteur ; Swantje MATTHIES, Auteur ; Patricia BOREL, Auteur ; Klaus HENNIGHAUSEN, Auteur ; Barbara HAACK-DEES, Auteur ; Michael RÖSLER, Auteur ; Wolfgang RETZ, Auteur ; Alexander VON GONTARD, Auteur ; Susann HÄNIG, Auteur ; Esther SOBANSKI, Auteur ; Barbara ALM, Auteur ; Luise POUSTKA, Auteur ; Sarah HOHMANN, Auteur ; Michael COLLA, Auteur ; Laura GENTSCHOW, Auteur ; Charlotte JAITE, Auteur ; Viola KAPPEL, Auteur ; Katja BECKER, Auteur ; Martin HOLTMANN, Auteur ; Christine FREITAG, Auteur ; Erika GRAF, Auteur ; Gabriele IHORST, Auteur ; Alexandra PHILIPSEN, Auteur . - p.1298-1313.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-12 (December 2015) . - p.1298-1313
Mots-clés : Parental ADHD parent training dialectical behavioral therapy stimulant medication Index. décimale : PER Périodiques Résumé : Background This is the first randomized controlled multicenter trial to evaluate the effect of two treatments of maternal attention-deficit hyperactivity disorder (ADHD) on response to parent–child training targeting children's external psychopathology. Methods Mother–child dyads (n = 144; ADHD according to DSM-IV; children: 73.5% males, mean age 9.4 years) from five specialized university outpatient units in Germany were centrally randomized to multimodal maternal ADHD treatment [group psychotherapy plus open methylphenidate medication; treatment group (TG): n = 77] or to clinical management [supportive counseling without psychotherapy or psychopharmacotherapy; control group (CG): n = 67]. After 12 weeks, the maternal ADHD treatment was supplemented by individual parent–child training for all dyads. The primary outcome was a change in the children's externalizing symptom scores (investigator blinded to the treatment assignment) from baseline to the end of the parent–child training 6 months later. Maintenance therapy continued for another 6 months. An intention-to-treat analysis was performed within a linear regression model, controlling for baseline and center after multiple imputations of missing values. Results Exactly, 206 dyads were assessed for eligibility, 144 were randomized, and 143 were analyzed (TG: n = 77; CG: n = 66). After 6 months, no significant between-group differences were found in change scores for children's externalizing symptoms (adjusted mean TG-mean CG=1.1, 95% confidence interval ?0.5–2.7; p = .1854), although maternal psychopathology improved more in the TG. Children's externalizing symptom scores improved from a mean of 14.8 at baseline to 11.4 (TG) and 10.3 (CG) after 6 months and to 10.8 (TG) and 10.1 (CG) after 1 year. No severe harms related to study treatments were found, but adverse events were more frequent in TG mothers than in CG mothers. Conclusions The response in children's externalizing psychopathology did not differ between maternal treatment groups. However, multimodal treatment was associated with more improvement in maternal ADHD. Child and maternal treatment gains were stable (CCT-ISRCTN73911400). En ligne : http://dx.doi.org/10.1111/jcpp.12443 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273 Empathy in children with autism and conduct disorder: group-specific profiles and developmental aspects / Christina SCHWENCK in Journal of Child Psychology and Psychiatry, 53-6 (June 2012)
[article]
Titre : Empathy in children with autism and conduct disorder: group-specific profiles and developmental aspects Type de document : Texte imprimé et/ou numérique Auteurs : Christina SCHWENCK, Auteur ; Julia MERGENTHALER, Auteur ; Katharina KELLER, Auteur ; Julie ZECH, Auteur ; Sarah SALEHI, Auteur ; Regina TAURINES, Auteur ; Marcel ROMANOS, Auteur ; Martin SCHECKELMANN, Auteur ; Wolfgang SCHNEIDER, Auteur ; Andreas WARNKE, Auteur ; Christine M. FREITAG, Auteur Année de publication : 2012 Article en page(s) : p.651–659 Langues : Anglais (eng) Mots-clés : Empathy autism spectrum disorder conduct disorder callous-unemotional traits development Index. décimale : PER Périodiques Résumé : Background: A deficit in empathy is discussed to underlie difficulties in social interaction of children with autism spectrum disorder (ASD) and conduct disorder (CD). To date, no study has compared children with ASD and different subtypes of CD to describe disorder-specific empathy profiles in clinical samples. Furthermore, little is known about age influences on the development of empathic skills. The aim of the current study was to compare cognitive and emotional empathy in different age groups of children with ASD, CD with elevated or low callous-unemotional-traits (CU+ vs. CU−) and a matched control group (CG).
Methods: Fifty-five boys with ASD, 36 boys with CD-CU+, 34 boys with CD-CU− and 67 controls were included. The study implemented three tasks on emotion recognition, perspective taking and emotional affection induced by another person’s situation. Multivariate Analysis of variance with the factors group and age (median split) including their interaction term was performed to describe disorder-specific profiles.
Results: Empathy profiles showed differential impairment in children with ASD and CD-CU+. Boys with ASD were impaired in cognitive empathy while participants with CD-CU+ were impaired in emotional empathy. Children with CD-CU− did not differ from the CG. However, boys with CD-CU− were less emotionally reactive in response to film stimuli than children with ASD. Furthermore, we found strong age effects indicating an increase in cognitive and affective empathic skills beyond early infancy in all groups.
Conclusions: In this study, distinct empathic profiles in children with ASD and CD-CU+ were found. Furthermore, the work demonstrates improvement of empathic skills throughout childhood and adolescence, which is comparable for individuals with psychiatric disorders and control children. These results yield implications for further research as well as for therapeutic interventions.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02499.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=157
in Journal of Child Psychology and Psychiatry > 53-6 (June 2012) . - p.651–659[article] Empathy in children with autism and conduct disorder: group-specific profiles and developmental aspects [Texte imprimé et/ou numérique] / Christina SCHWENCK, Auteur ; Julia MERGENTHALER, Auteur ; Katharina KELLER, Auteur ; Julie ZECH, Auteur ; Sarah SALEHI, Auteur ; Regina TAURINES, Auteur ; Marcel ROMANOS, Auteur ; Martin SCHECKELMANN, Auteur ; Wolfgang SCHNEIDER, Auteur ; Andreas WARNKE, Auteur ; Christine M. FREITAG, Auteur . - 2012 . - p.651–659.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 53-6 (June 2012) . - p.651–659
Mots-clés : Empathy autism spectrum disorder conduct disorder callous-unemotional traits development Index. décimale : PER Périodiques Résumé : Background: A deficit in empathy is discussed to underlie difficulties in social interaction of children with autism spectrum disorder (ASD) and conduct disorder (CD). To date, no study has compared children with ASD and different subtypes of CD to describe disorder-specific empathy profiles in clinical samples. Furthermore, little is known about age influences on the development of empathic skills. The aim of the current study was to compare cognitive and emotional empathy in different age groups of children with ASD, CD with elevated or low callous-unemotional-traits (CU+ vs. CU−) and a matched control group (CG).
Methods: Fifty-five boys with ASD, 36 boys with CD-CU+, 34 boys with CD-CU− and 67 controls were included. The study implemented three tasks on emotion recognition, perspective taking and emotional affection induced by another person’s situation. Multivariate Analysis of variance with the factors group and age (median split) including their interaction term was performed to describe disorder-specific profiles.
Results: Empathy profiles showed differential impairment in children with ASD and CD-CU+. Boys with ASD were impaired in cognitive empathy while participants with CD-CU+ were impaired in emotional empathy. Children with CD-CU− did not differ from the CG. However, boys with CD-CU− were less emotionally reactive in response to film stimuli than children with ASD. Furthermore, we found strong age effects indicating an increase in cognitive and affective empathic skills beyond early infancy in all groups.
Conclusions: In this study, distinct empathic profiles in children with ASD and CD-CU+ were found. Furthermore, the work demonstrates improvement of empathic skills throughout childhood and adolescence, which is comparable for individuals with psychiatric disorders and control children. These results yield implications for further research as well as for therapeutic interventions.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02499.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=157