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Auteur James G. SCOTT |
Documents disponibles écrits par cet auteur (5)
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Hypertensive disorders of pregnancy and the risk of offspring depression in childhood: Findings from the Avon Longitudinal Study of Parents and Children / Berihun Assefa DACHEW in Development and Psychopathology, 32-3 (August 2020)
[article]
Titre : Hypertensive disorders of pregnancy and the risk of offspring depression in childhood: Findings from the Avon Longitudinal Study of Parents and Children Type de document : Texte imprimé et/ou numérique Auteurs : Berihun Assefa DACHEW, Auteur ; James G. SCOTT, Auteur ; Kim S. BETTS, Auteur ; Abdullah MAMUN, Auteur ; Rosa ALATI, Auteur Article en page(s) : p.845-851 Langues : Anglais (eng) Mots-clés : Alspac childhood depression hypertensive disorders of pregnancy offspring Index. décimale : PER Périodiques Résumé : Hypertensive disorders of pregnancy (HDP) may increase the risk of offspring depression in childhood. Low birth weight is also associated with increased risk of mental health problems, including depression. This study sought to investigate (a) whether there is an association between HDP and the risk of depression in childhood and (b) whether low birth weight mediates this association. The current study is based on the Avon Longitudinal Study of Parents and Children (ALSPAC), a prospective, population-based study that has followed a cohort of offspring since their mothers were pregnant (n = 6,739). Depression at the age of 7 years was diagnosed using parent reports via the Development and Well-Being Assessment (DAWBA). Log-binomial regression and mediation analyses were used. Children exposed to HDP were 2.3 times more likely to have a depression diagnosis compared with nonexposed children, adjusted Risk Ratio [RR], 2.31; 95% CI, [1.20, 4.47]. Low birth weight was a weak mediator of this association. Results were adjusted for confounding variables including antenatal depression and anxiety during pregnancy.This study suggests that fetal exposure to maternal hypertensive disorders of pregnancy increased the risk of childhood depression. The study adds to the evidence suggesting that the uterine environment is a critical determinant of neurodevelopmental and psychiatric outcomes. En ligne : http://dx.doi.org/10.1017/s0954579419000944 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429
in Development and Psychopathology > 32-3 (August 2020) . - p.845-851[article] Hypertensive disorders of pregnancy and the risk of offspring depression in childhood: Findings from the Avon Longitudinal Study of Parents and Children [Texte imprimé et/ou numérique] / Berihun Assefa DACHEW, Auteur ; James G. SCOTT, Auteur ; Kim S. BETTS, Auteur ; Abdullah MAMUN, Auteur ; Rosa ALATI, Auteur . - p.845-851.
Langues : Anglais (eng)
in Development and Psychopathology > 32-3 (August 2020) . - p.845-851
Mots-clés : Alspac childhood depression hypertensive disorders of pregnancy offspring Index. décimale : PER Périodiques Résumé : Hypertensive disorders of pregnancy (HDP) may increase the risk of offspring depression in childhood. Low birth weight is also associated with increased risk of mental health problems, including depression. This study sought to investigate (a) whether there is an association between HDP and the risk of depression in childhood and (b) whether low birth weight mediates this association. The current study is based on the Avon Longitudinal Study of Parents and Children (ALSPAC), a prospective, population-based study that has followed a cohort of offspring since their mothers were pregnant (n = 6,739). Depression at the age of 7 years was diagnosed using parent reports via the Development and Well-Being Assessment (DAWBA). Log-binomial regression and mediation analyses were used. Children exposed to HDP were 2.3 times more likely to have a depression diagnosis compared with nonexposed children, adjusted Risk Ratio [RR], 2.31; 95% CI, [1.20, 4.47]. Low birth weight was a weak mediator of this association. Results were adjusted for confounding variables including antenatal depression and anxiety during pregnancy.This study suggests that fetal exposure to maternal hypertensive disorders of pregnancy increased the risk of childhood depression. The study adds to the evidence suggesting that the uterine environment is a critical determinant of neurodevelopmental and psychiatric outcomes. En ligne : http://dx.doi.org/10.1017/s0954579419000944 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study / Rebecca M. ARMSTRONG in Journal of Autism and Developmental Disorders, 47-5 (May 2017)
[article]
Titre : A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca M. ARMSTRONG, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; James G. SCOTT, Auteur ; David A. COPLAND, Auteur ; Katie L. MCMAHON, Auteur ; Sophie FLEMING, Auteur ; Wendy ARNOTT, Auteur Article en page(s) : p.1478-1489 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Autistic-like traits Early language skills Late talking Raine Study Index. décimale : PER Périodiques Résumé : The current study examined the relationship between early language ability and autistic-like traits in adulthood, utilising data from 644 participants from a longitudinal study of the general population. Language performance at 2 years was measured with the Language Development Survey (LDS), and at 20 years the participants completed the Autism-Spectrum Quotient (AQ). Vocabulary size at 2 years was negatively associated with Total AQ score, as well as scores on the Communication, and Social Skills subscales. Adults who had been late talkers were also more likely to have ‘high’ scores on the Communication subscale. This is the first study to show an association between early language ability and autistic-like traits in adulthood. En ligne : http://dx.doi.org/10.1007/s10803-016-3014-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305
in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1478-1489[article] A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study [Texte imprimé et/ou numérique] / Rebecca M. ARMSTRONG, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; James G. SCOTT, Auteur ; David A. COPLAND, Auteur ; Katie L. MCMAHON, Auteur ; Sophie FLEMING, Auteur ; Wendy ARNOTT, Auteur . - p.1478-1489.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1478-1489
Mots-clés : Autism spectrum disorder Autistic-like traits Early language skills Late talking Raine Study Index. décimale : PER Périodiques Résumé : The current study examined the relationship between early language ability and autistic-like traits in adulthood, utilising data from 644 participants from a longitudinal study of the general population. Language performance at 2 years was measured with the Language Development Survey (LDS), and at 20 years the participants completed the Autism-Spectrum Quotient (AQ). Vocabulary size at 2 years was negatively associated with Total AQ score, as well as scores on the Communication, and Social Skills subscales. Adults who had been late talkers were also more likely to have ‘high’ scores on the Communication subscale. This is the first study to show an association between early language ability and autistic-like traits in adulthood. En ligne : http://dx.doi.org/10.1007/s10803-016-3014-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 Research Review: Epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010 / Holly E. ERSKINE in Journal of Child Psychology and Psychiatry, 54-12 (December 2013)
[article]
Titre : Research Review: Epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010 Type de document : Texte imprimé et/ou numérique Auteurs : Holly E. ERSKINE, Auteur ; Alize J. FERRARI, Auteur ; Paul NELSON, Auteur ; Guilherme V. POLANCZYK, Auteur ; Abraham D. FLAXMAN, Auteur ; Theo VOS, Auteur ; Harvey A. WHITEFORD, Auteur ; James G. SCOTT, Auteur Article en page(s) : p.1263-1274 Langues : Anglais (eng) Mots-clés : Global burden of disease study 2010 attention-deficit/hyperactivity disorder conduct disorder prevalence statistical modelling Index. décimale : PER Périodiques Résumé : Background The most recent Global Burden of Disease Study (GBD 2010) is the first to include attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) for burden quantification. We present the epidemiological profiles of ADHD and CD across three time periods for 21 world regions. Methods A systematic review of global epidemiology was conducted for each disorder (based on a literature search of the Medline, PsycInfo and EMBASE databases). A Bayesian metaregression tool was used to derive prevalence estimates by age and sex in three time periods (1990, 2005 and 2010) for 21 world regions including those with little or no data. Prior expert knowledge and covariates were applied to each model to adjust suboptimal data. Final prevalence output for ADHD were adjusted to reflect an equivalent value if studies had measured point prevalence using multiple informants while final prevalence output for CD were adjusted to reflect a value equivalent to CD only. Results Prevalence was pooled for males and females aged 5–19 years with no difference found in global prevalence between the three time periods. Male prevalence of ADHD in 2010 was 2.2% (2.0–2.3) while female prevalence was 0.7% (0.6–0.7). Male prevalence of CD in 2010 was 3.6% (3.3–4.0) while female prevalence was 1.5% (1.4–1.7). ADHD and CD were estimated to be present worldwide with ADHD prevalence showing some regional variation while CD prevalence remained relatively consistent worldwide. Conclusions We present the first prevalence estimates of both ADHD and CD globally and for all world regions. Data were sparse with large parts of the world having no estimates of either disorder. Epidemiological studies are urgently needed in certain parts of the world. Our findings directly informed burden quantification for GBD 2010. As mental disorders gained increased recognition after the first GBD study in 1990, the inclusion of ADHD and CD in GBD 2010 ensures their importance will be recognized alongside other childhood disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12144 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219
in Journal of Child Psychology and Psychiatry > 54-12 (December 2013) . - p.1263-1274[article] Research Review: Epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010 [Texte imprimé et/ou numérique] / Holly E. ERSKINE, Auteur ; Alize J. FERRARI, Auteur ; Paul NELSON, Auteur ; Guilherme V. POLANCZYK, Auteur ; Abraham D. FLAXMAN, Auteur ; Theo VOS, Auteur ; Harvey A. WHITEFORD, Auteur ; James G. SCOTT, Auteur . - p.1263-1274.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 54-12 (December 2013) . - p.1263-1274
Mots-clés : Global burden of disease study 2010 attention-deficit/hyperactivity disorder conduct disorder prevalence statistical modelling Index. décimale : PER Périodiques Résumé : Background The most recent Global Burden of Disease Study (GBD 2010) is the first to include attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) for burden quantification. We present the epidemiological profiles of ADHD and CD across three time periods for 21 world regions. Methods A systematic review of global epidemiology was conducted for each disorder (based on a literature search of the Medline, PsycInfo and EMBASE databases). A Bayesian metaregression tool was used to derive prevalence estimates by age and sex in three time periods (1990, 2005 and 2010) for 21 world regions including those with little or no data. Prior expert knowledge and covariates were applied to each model to adjust suboptimal data. Final prevalence output for ADHD were adjusted to reflect an equivalent value if studies had measured point prevalence using multiple informants while final prevalence output for CD were adjusted to reflect a value equivalent to CD only. Results Prevalence was pooled for males and females aged 5–19 years with no difference found in global prevalence between the three time periods. Male prevalence of ADHD in 2010 was 2.2% (2.0–2.3) while female prevalence was 0.7% (0.6–0.7). Male prevalence of CD in 2010 was 3.6% (3.3–4.0) while female prevalence was 1.5% (1.4–1.7). ADHD and CD were estimated to be present worldwide with ADHD prevalence showing some regional variation while CD prevalence remained relatively consistent worldwide. Conclusions We present the first prevalence estimates of both ADHD and CD globally and for all world regions. Data were sparse with large parts of the world having no estimates of either disorder. Epidemiological studies are urgently needed in certain parts of the world. Our findings directly informed burden quantification for GBD 2010. As mental disorders gained increased recognition after the first GBD study in 1990, the inclusion of ADHD and CD in GBD 2010 ensures their importance will be recognized alongside other childhood disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12144 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219 Research Review: The role of cytokines in depression in adolescents: a systematic review / Natalie T. MILLS in Journal of Child Psychology and Psychiatry, 54-8 (August 2013)
[article]
Titre : Research Review: The role of cytokines in depression in adolescents: a systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Natalie T. MILLS, Auteur ; James G. SCOTT, Auteur ; Naomi R. WRAY, Auteur ; Sarah COHEN-WOODS, Auteur ; BERNHARD T. BAUNE, Auteur Article en page(s) : p.816-835 Langues : Anglais (eng) Mots-clés : Cytokines inflammation immune system MDD cognition stress Index. décimale : PER Périodiques Résumé : Background While cytokines have been implicated in the pathophysiology of depression in adults, the potential role in younger age groups such as adolescents is less clear. This article therefore reviews the literature (a) to explore the relationship between cytokines and depression in adolescents, and (b) to examine how cytokines may be related to adolescent depression in the context of other neurobiological theories of depression. Method A systematic review of the scientific literature on the subject was conducted in February 2013, searching the Web of Knowledge, PubMed (Medline), PsycInfo and Cochrane electronic databases. Results Eighteen studies were identified measuring both depression or depressive symptoms and cytokines or immune markers in adolescents. Adolescents with depression show age-specific characteristics of the immune and inflammatory system, specifically in NK cell activity and in pro-inflammatory cytokines (such as IL-1? and TNF-?). In addition, the role of cytokines in adolescent depression is influenced by neurodevelopment, hormonal changes, stress and trauma. Conclusions There may be differences in the neurobiology of adolescent major depressive disorder (MDD) compared with adult MDD. Increased understanding of the role of cytokines in adolescent MDD may lead to improved outcomes in the treatment of adolescent depression. En ligne : http://dx.doi.org/10.1111/jcpp.12080 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210
in Journal of Child Psychology and Psychiatry > 54-8 (August 2013) . - p.816-835[article] Research Review: The role of cytokines in depression in adolescents: a systematic review [Texte imprimé et/ou numérique] / Natalie T. MILLS, Auteur ; James G. SCOTT, Auteur ; Naomi R. WRAY, Auteur ; Sarah COHEN-WOODS, Auteur ; BERNHARD T. BAUNE, Auteur . - p.816-835.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 54-8 (August 2013) . - p.816-835
Mots-clés : Cytokines inflammation immune system MDD cognition stress Index. décimale : PER Périodiques Résumé : Background While cytokines have been implicated in the pathophysiology of depression in adults, the potential role in younger age groups such as adolescents is less clear. This article therefore reviews the literature (a) to explore the relationship between cytokines and depression in adolescents, and (b) to examine how cytokines may be related to adolescent depression in the context of other neurobiological theories of depression. Method A systematic review of the scientific literature on the subject was conducted in February 2013, searching the Web of Knowledge, PubMed (Medline), PsycInfo and Cochrane electronic databases. Results Eighteen studies were identified measuring both depression or depressive symptoms and cytokines or immune markers in adolescents. Adolescents with depression show age-specific characteristics of the immune and inflammatory system, specifically in NK cell activity and in pro-inflammatory cytokines (such as IL-1? and TNF-?). In addition, the role of cytokines in adolescent depression is influenced by neurodevelopment, hormonal changes, stress and trauma. Conclusions There may be differences in the neurobiology of adolescent major depressive disorder (MDD) compared with adult MDD. Increased understanding of the role of cytokines in adolescent MDD may lead to improved outcomes in the treatment of adolescent depression. En ligne : http://dx.doi.org/10.1111/jcpp.12080 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210 The global burden of conduct disorder and attention-deficit/hyperactivity disorder in 2010 / Holly E. ERSKINE in Journal of Child Psychology and Psychiatry, 55-4 (April 2014)
[article]
Titre : The global burden of conduct disorder and attention-deficit/hyperactivity disorder in 2010 Type de document : Texte imprimé et/ou numérique Auteurs : Holly E. ERSKINE, Auteur ; Alize J. FERRARI, Auteur ; Guilherme V. POLANCZYK, Auteur ; Terrie E. MOFFITT, Auteur ; Christopher J. L. MURRAY, Auteur ; Theo VOS, Auteur ; Harvey A. WHITEFORD, Auteur ; James G. SCOTT, Auteur Article en page(s) : p.328-336 Mots-clés : Global burden of disease study 2010 conduct disorder attention-deficit/hyperactivity disorder disability-adjusted life year years lived with disability Index. décimale : PER Périodiques Résumé : Objective The Global Burden of Disease Study 2010 (GBD 2010) is the first to include conduct disorder (CD) and attention-deficit/hyperactivity disorder (ADHD) for burden quantification. Method A previous systematic review pooled the available epidemiological data for CD and ADHD, and predicted prevalence by country, region, age and sex for each disorder. Prevalence was then multiplied by a disability weight to calculate years lived with disability (YLDs). As no evidence of deaths resulting directly from either CD or ADHD was found, no years of life lost (YLLs) were calculated. Therefore, the number of disability-adjusted life years (DALYs) was equal to that of YLDs. Results Globally, CD was responsible for 5.75 million YLDs/DALYs with ADHD responsible for a further 491,500. Collectively, CD and ADHD accounted for 0.80% of total global YLDs and 0.25% of total global DALYs. In terms of global DALYs, CD was the 72nd leading contributor and among the 15 leading causes in children aged 5–19 years. Between 1990 and 2010, global DALYs attributable to CD and ADHD remained stable after accounting for population growth and ageing. Conclusions The global burden of CD and ADHD is significant, particularly in male children. Appropriate allocation of resources to address the high morbidity associated with CD and ADHD is necessary to reduce global burden. However, burden estimation was limited by data lacking for all four epidemiological parameters and by methodological challenges in quantifying disability. Future studies need to address these limitations in order to increase the accuracy of burden quantification. En ligne : http://dx.doi.org/10.1111/jcpp.12186 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=229
in Journal of Child Psychology and Psychiatry > 55-4 (April 2014) . - p.328-336[article] The global burden of conduct disorder and attention-deficit/hyperactivity disorder in 2010 [Texte imprimé et/ou numérique] / Holly E. ERSKINE, Auteur ; Alize J. FERRARI, Auteur ; Guilherme V. POLANCZYK, Auteur ; Terrie E. MOFFITT, Auteur ; Christopher J. L. MURRAY, Auteur ; Theo VOS, Auteur ; Harvey A. WHITEFORD, Auteur ; James G. SCOTT, Auteur . - p.328-336.
in Journal of Child Psychology and Psychiatry > 55-4 (April 2014) . - p.328-336
Mots-clés : Global burden of disease study 2010 conduct disorder attention-deficit/hyperactivity disorder disability-adjusted life year years lived with disability Index. décimale : PER Périodiques Résumé : Objective The Global Burden of Disease Study 2010 (GBD 2010) is the first to include conduct disorder (CD) and attention-deficit/hyperactivity disorder (ADHD) for burden quantification. Method A previous systematic review pooled the available epidemiological data for CD and ADHD, and predicted prevalence by country, region, age and sex for each disorder. Prevalence was then multiplied by a disability weight to calculate years lived with disability (YLDs). As no evidence of deaths resulting directly from either CD or ADHD was found, no years of life lost (YLLs) were calculated. Therefore, the number of disability-adjusted life years (DALYs) was equal to that of YLDs. Results Globally, CD was responsible for 5.75 million YLDs/DALYs with ADHD responsible for a further 491,500. Collectively, CD and ADHD accounted for 0.80% of total global YLDs and 0.25% of total global DALYs. In terms of global DALYs, CD was the 72nd leading contributor and among the 15 leading causes in children aged 5–19 years. Between 1990 and 2010, global DALYs attributable to CD and ADHD remained stable after accounting for population growth and ageing. Conclusions The global burden of CD and ADHD is significant, particularly in male children. Appropriate allocation of resources to address the high morbidity associated with CD and ADHD is necessary to reduce global burden. However, burden estimation was limited by data lacking for all four epidemiological parameters and by methodological challenges in quantifying disability. Future studies need to address these limitations in order to increase the accuracy of burden quantification. En ligne : http://dx.doi.org/10.1111/jcpp.12186 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=229