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Auteur T. FALCK-YTTER |
Documents disponibles écrits par cet auteur (14)
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Altered gaze following during live interaction in infants at risk for autism: an eye tracking study / E. THORUP in Molecular Autism, 7 (2016)
[article]
Titre : Altered gaze following during live interaction in infants at risk for autism: an eye tracking study Type de document : Texte imprimé et/ou numérique Auteurs : E. THORUP, Auteur ; P. NYSTROM, Auteur ; G. GREDEBACK, Auteur ; Sven BÖLTE, Auteur ; T. FALCK-YTTER, Auteur Article en page(s) : 12p. Langues : Anglais (eng) Mots-clés : Attention/physiology Autism Spectrum Disorder/diagnosis/epidemiology/physiopathology Cues Early Diagnosis Eye Movements Family Health Female Fixation, Ocular/physiology Head Movements Humans Imitative Behavior/physiology Infant Male Pursuit, Smooth/physiology Risk Single-Blind Method Social Behavior Social Perception Autism Communication Early development Gaze following Joint attention Neurodevelopmental disorders Social cognition Younger siblings Index. décimale : PER Périodiques Résumé : BACKGROUND: The ability to follow gaze is an important prerequisite for joint attention, which is often compromised in children with autism spectrum disorder (ASD). The direction of both the head and eyes provides cues to other people's attention direction, but previous studies have not separated these factors and their relation to ASD susceptibility. Development of gaze following typically occurs before ASD diagnosis is possible, and studies of high-risk populations are therefore important. METHODS: Eye tracking was used to assess gaze following during interaction in a group of 10-month-old infants at high familial risk for ASD (high-risk group) as well as a group of infants with no family history of ASD (low-risk group). The infants watched an experimenter gaze at objects in the periphery. Performance was compared across two conditions: one in which the experimenter moved both the eyes and head toward the objects (Eyes and Head condition) and one that involved movement of the eyes only (Eyes Only condition). RESULTS: A group by condition interaction effect was found. Specifically, whereas gaze following accuracy was comparable across the two conditions in the low-risk group, infants in the high-risk group were more likely to follow gaze in the Eyes and Head condition than in the Eyes Only condition. CONCLUSIONS: In an ecologically valid social situation, responses to basic non-verbal orienting cues were found to be altered in infants at risk for ASD. The results indicate that infants at risk for ASD may rely disproportionally on information from the head when following gaze and point to the importance of separating information from the eyes and the head when studying social perception in ASD. En ligne : http://dx.doi.org/10.1186/s13229-016-0069-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=329
in Molecular Autism > 7 (2016) . - 12p.[article] Altered gaze following during live interaction in infants at risk for autism: an eye tracking study [Texte imprimé et/ou numérique] / E. THORUP, Auteur ; P. NYSTROM, Auteur ; G. GREDEBACK, Auteur ; Sven BÖLTE, Auteur ; T. FALCK-YTTER, Auteur . - 12p.
Langues : Anglais (eng)
in Molecular Autism > 7 (2016) . - 12p.
Mots-clés : Attention/physiology Autism Spectrum Disorder/diagnosis/epidemiology/physiopathology Cues Early Diagnosis Eye Movements Family Health Female Fixation, Ocular/physiology Head Movements Humans Imitative Behavior/physiology Infant Male Pursuit, Smooth/physiology Risk Single-Blind Method Social Behavior Social Perception Autism Communication Early development Gaze following Joint attention Neurodevelopmental disorders Social cognition Younger siblings Index. décimale : PER Périodiques Résumé : BACKGROUND: The ability to follow gaze is an important prerequisite for joint attention, which is often compromised in children with autism spectrum disorder (ASD). The direction of both the head and eyes provides cues to other people's attention direction, but previous studies have not separated these factors and their relation to ASD susceptibility. Development of gaze following typically occurs before ASD diagnosis is possible, and studies of high-risk populations are therefore important. METHODS: Eye tracking was used to assess gaze following during interaction in a group of 10-month-old infants at high familial risk for ASD (high-risk group) as well as a group of infants with no family history of ASD (low-risk group). The infants watched an experimenter gaze at objects in the periphery. Performance was compared across two conditions: one in which the experimenter moved both the eyes and head toward the objects (Eyes and Head condition) and one that involved movement of the eyes only (Eyes Only condition). RESULTS: A group by condition interaction effect was found. Specifically, whereas gaze following accuracy was comparable across the two conditions in the low-risk group, infants in the high-risk group were more likely to follow gaze in the Eyes and Head condition than in the Eyes Only condition. CONCLUSIONS: In an ecologically valid social situation, responses to basic non-verbal orienting cues were found to be altered in infants at risk for ASD. The results indicate that infants at risk for ASD may rely disproportionally on information from the head when following gaze and point to the importance of separating information from the eyes and the head when studying social perception in ASD. En ligne : http://dx.doi.org/10.1186/s13229-016-0069-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=329 Autistic Traits and Symptoms of Social Anxiety are Differentially Related to Attention to Others' Eyes in Social Anxiety Disorder / J. L. KLEBERG in Journal of Autism and Developmental Disorders, 47-12 (December 2017)
[article]
Titre : Autistic Traits and Symptoms of Social Anxiety are Differentially Related to Attention to Others' Eyes in Social Anxiety Disorder Type de document : Texte imprimé et/ou numérique Auteurs : J. L. KLEBERG, Auteur ; J. HOGSTROM, Auteur ; M. NORD, Auteur ; Sven BÖLTE, Auteur ; E. SERLACHIUS, Auteur ; T. FALCK-YTTER, Auteur Année de publication : 2017 Article en page(s) : p.3814-3821 Langues : Anglais (eng) Mots-clés : Attention Autism spectrum disorder (ASD) Avoidance Broader autism phenotype Eye tracking Gaze avoidance Orienting Social anxiety disorder (SAD) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and social anxiety disorder (SAD) have partly overlapping symptoms. Gaze avoidance has been linked to both SAD and ASD, but little is known about differences in social attention between the two conditions. We studied eye movements in a group of treatment-seeking adolescents with SAD (N = 25), assessing SAD and ASD dimensionally. The results indicated a double dissociation between two measures of social attention and the two symptom dimensions. Controlling for social anxiety, elevated autistic traits were associated with delayed orienting to eyes presented among distractors. In contrast, elevated social anxiety levels were associated with faster orienting away from the eyes, when controlling for autistic traits. This distinction deepens our understanding of ASD and SAD. En ligne : http://dx.doi.org/10.1007/s10803-016-2978-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325
in Journal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3814-3821[article] Autistic Traits and Symptoms of Social Anxiety are Differentially Related to Attention to Others' Eyes in Social Anxiety Disorder [Texte imprimé et/ou numérique] / J. L. KLEBERG, Auteur ; J. HOGSTROM, Auteur ; M. NORD, Auteur ; Sven BÖLTE, Auteur ; E. SERLACHIUS, Auteur ; T. FALCK-YTTER, Auteur . - 2017 . - p.3814-3821.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3814-3821
Mots-clés : Attention Autism spectrum disorder (ASD) Avoidance Broader autism phenotype Eye tracking Gaze avoidance Orienting Social anxiety disorder (SAD) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and social anxiety disorder (SAD) have partly overlapping symptoms. Gaze avoidance has been linked to both SAD and ASD, but little is known about differences in social attention between the two conditions. We studied eye movements in a group of treatment-seeking adolescents with SAD (N = 25), assessing SAD and ASD dimensionally. The results indicated a double dissociation between two measures of social attention and the two symptom dimensions. Controlling for social anxiety, elevated autistic traits were associated with delayed orienting to eyes presented among distractors. In contrast, elevated social anxiety levels were associated with faster orienting away from the eyes, when controlling for autistic traits. This distinction deepens our understanding of ASD and SAD. En ligne : http://dx.doi.org/10.1007/s10803-016-2978-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325 Development of the pupillary light reflex from 9 to 24 months: association with common autism spectrum disorder (ASD) genetic liability and 3-year ASD diagnosis / L. A. FISH in Journal of Child Psychology and Psychiatry, 62-11 (November 2021)
[article]
Titre : Development of the pupillary light reflex from 9 to 24 months: association with common autism spectrum disorder (ASD) genetic liability and 3-year ASD diagnosis Type de document : Texte imprimé et/ou numérique Auteurs : L. A. FISH, Auteur ; P. NYSTROM, Auteur ; T. GLIGA, Auteur ; A. GUI, Auteur ; Jannath BEGUM ALI, Auteur ; L. MASON, Auteur ; S. GARG, Auteur ; J. GREEN, Auteur ; M. H. JOHNSON, Auteur ; Tony CHARMAN, Auteur ; R. HARRISON, Auteur ; E. MEABURN, Auteur ; T. FALCK-YTTER, Auteur ; E. J. H. JONES, Auteur Article en page(s) : p.1308-1319 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/genetics Humans Infant Phenotype Reflex Autism spectrum disorder infancy neurodevelopment pupillary light reflex Index. décimale : PER Périodiques Résumé : BACKGROUND: Although autism spectrum disorder (ASD) is heritable, the mechanisms through which genes contribute to symptom emergence remain unclear. Investigating candidate intermediate phenotypes such as the pupillary light reflex (PLR) prospectively from early in development could bridge genotype and behavioural phenotype. METHODS: Using eye tracking, we longitudinally measured the PLR at 9, 14 and 24 months in a sample of infants (N = 264) enriched for a family history of ASD; 27 infants received an ASD diagnosis at 3 years. We examined the 9- to 24-month developmental trajectories of PLR constriction latency (onset; ms) and amplitude (%) and explored their relation to categorical 3-year ASD outcome, polygenic liability for ASD and dimensional 3-year social affect (SA) and repetitive/restrictive behaviour (RRB) traits. Polygenic scores for ASD (PGS(ASD) ) were calculated for 190 infants. RESULTS: While infants showed a decrease in latency between 9 and 14 months, higher PGS(ASD) was associated with a smaller decrease in latency in the first year (? = -.16, 95% CI = -0.31, -0.002); infants with later ASD showed a significantly steeper decrease in latency (a putative 'catch-up') between 14 and 24 months relative to those with other outcomes (typical: ? = .54, 95% CI = 0.08, 0.99; other: ? = .53, 95% CI = 0.02, 1.04). Latency development did not associate with later dimensional variation in ASD-related traits. In contrast, change in amplitude was not related to categorical ASD or genetics, but decreasing 9- to 14-month amplitude was associated with higher SA (? = .08, 95% CI = 0.01, 0.14) and RRB (? = .05, 95% CI = 0.004, 0.11) traits. CONCLUSIONS: These findings corroborate PLR development as possible intermediate phenotypes being linked to both genetic liability and phenotypic outcomes. Future work should incorporate alternative measures (e.g. functionally informed structural and genetic measures) to test whether distinct neural mechanisms underpin PLR alterations. En ligne : http://dx.doi.org/10.1111/jcpp.13518 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-11 (November 2021) . - p.1308-1319[article] Development of the pupillary light reflex from 9 to 24 months: association with common autism spectrum disorder (ASD) genetic liability and 3-year ASD diagnosis [Texte imprimé et/ou numérique] / L. A. FISH, Auteur ; P. NYSTROM, Auteur ; T. GLIGA, Auteur ; A. GUI, Auteur ; Jannath BEGUM ALI, Auteur ; L. MASON, Auteur ; S. GARG, Auteur ; J. GREEN, Auteur ; M. H. JOHNSON, Auteur ; Tony CHARMAN, Auteur ; R. HARRISON, Auteur ; E. MEABURN, Auteur ; T. FALCK-YTTER, Auteur ; E. J. H. JONES, Auteur . - p.1308-1319.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-11 (November 2021) . - p.1308-1319
Mots-clés : Autism Spectrum Disorder/diagnosis/genetics Humans Infant Phenotype Reflex Autism spectrum disorder infancy neurodevelopment pupillary light reflex Index. décimale : PER Périodiques Résumé : BACKGROUND: Although autism spectrum disorder (ASD) is heritable, the mechanisms through which genes contribute to symptom emergence remain unclear. Investigating candidate intermediate phenotypes such as the pupillary light reflex (PLR) prospectively from early in development could bridge genotype and behavioural phenotype. METHODS: Using eye tracking, we longitudinally measured the PLR at 9, 14 and 24 months in a sample of infants (N = 264) enriched for a family history of ASD; 27 infants received an ASD diagnosis at 3 years. We examined the 9- to 24-month developmental trajectories of PLR constriction latency (onset; ms) and amplitude (%) and explored their relation to categorical 3-year ASD outcome, polygenic liability for ASD and dimensional 3-year social affect (SA) and repetitive/restrictive behaviour (RRB) traits. Polygenic scores for ASD (PGS(ASD) ) were calculated for 190 infants. RESULTS: While infants showed a decrease in latency between 9 and 14 months, higher PGS(ASD) was associated with a smaller decrease in latency in the first year (? = -.16, 95% CI = -0.31, -0.002); infants with later ASD showed a significantly steeper decrease in latency (a putative 'catch-up') between 14 and 24 months relative to those with other outcomes (typical: ? = .54, 95% CI = 0.08, 0.99; other: ? = .53, 95% CI = 0.02, 1.04). Latency development did not associate with later dimensional variation in ASD-related traits. In contrast, change in amplitude was not related to categorical ASD or genetics, but decreasing 9- to 14-month amplitude was associated with higher SA (? = .08, 95% CI = 0.01, 0.14) and RRB (? = .05, 95% CI = 0.004, 0.11) traits. CONCLUSIONS: These findings corroborate PLR development as possible intermediate phenotypes being linked to both genetic liability and phenotypic outcomes. Future work should incorporate alternative measures (e.g. functionally informed structural and genetic measures) to test whether distinct neural mechanisms underpin PLR alterations. En ligne : http://dx.doi.org/10.1111/jcpp.13518 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 Eye tracking in early autism research / T. FALCK-YTTER in Journal of Neurodevelopmental Disorders, 5-1 (December 2013)
[article]
Titre : Eye tracking in early autism research Type de document : Texte imprimé et/ou numérique Auteurs : T. FALCK-YTTER, Auteur ; Sven BÖLTE, Auteur ; G. GREDEBACK, Auteur Article en page(s) : p.28 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Eye tracking has the potential to characterize autism at a unique intermediate level, with links 'down' to underlying neurocognitive networks, as well as 'up' to everyday function and dysfunction. Because it is non-invasive and does not require advanced motor responses or language, eye tracking is particularly important for the study of young children and infants. In this article, we review eye tracking studies of young children with autism spectrum disorder (ASD) and children at risk for ASD. Reduced looking time at people and faces, as well as problems with disengagement of attention, appear to be among the earliest signs of ASD, emerging during the first year of life. In toddlers with ASD, altered looking patterns across facial parts such as the eyes and mouth have been found, together with limited orienting to biological motion. We provide a detailed discussion of these and other key findings and highlight methodological opportunities and challenges for eye tracking research of young children with ASD. We conclude that eye tracking can reveal important features of the complex picture of autism. En ligne : http://dx.doi.org/10.1186/1866-1955-5-28 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=345
in Journal of Neurodevelopmental Disorders > 5-1 (December 2013) . - p.28[article] Eye tracking in early autism research [Texte imprimé et/ou numérique] / T. FALCK-YTTER, Auteur ; Sven BÖLTE, Auteur ; G. GREDEBACK, Auteur . - p.28.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 5-1 (December 2013) . - p.28
Index. décimale : PER Périodiques Résumé : Eye tracking has the potential to characterize autism at a unique intermediate level, with links 'down' to underlying neurocognitive networks, as well as 'up' to everyday function and dysfunction. Because it is non-invasive and does not require advanced motor responses or language, eye tracking is particularly important for the study of young children and infants. In this article, we review eye tracking studies of young children with autism spectrum disorder (ASD) and children at risk for ASD. Reduced looking time at people and faces, as well as problems with disengagement of attention, appear to be among the earliest signs of ASD, emerging during the first year of life. In toddlers with ASD, altered looking patterns across facial parts such as the eyes and mouth have been found, together with limited orienting to biological motion. We provide a detailed discussion of these and other key findings and highlight methodological opportunities and challenges for eye tracking research of young children with ASD. We conclude that eye tracking can reveal important features of the complex picture of autism. En ligne : http://dx.doi.org/10.1186/1866-1955-5-28 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=345 How Does Temperament in Toddlers at Elevated Likelihood for Autism Relate to Symptoms of Autism and ADHD at Three Years of Age? / L. A. KONKE in Journal of Autism and Developmental Disorders, 52-3 (March 2022)
[article]
Titre : How Does Temperament in Toddlers at Elevated Likelihood for Autism Relate to Symptoms of Autism and ADHD at Three Years of Age? Type de document : Texte imprimé et/ou numérique Auteurs : L. A. KONKE, Auteur ; T. FORSLUND, Auteur ; E. NILSSON-JOBS, Auteur ; P. NYSTROM, Auteur ; T. FALCK-YTTER, Auteur ; Karin C. BROCKI, Auteur Article en page(s) : p.995-1006 Langues : Anglais (eng) Mots-clés : Attention Deficit Disorder with Hyperactivity/diagnosis/epidemiology Autism Spectrum Disorder/diagnosis Autistic Disorder Child, Preschool Humans Infant Parents Temperament Attention-Deficit/Hyperactivity Disorder Autism Spectrum Disorder Infant Sibling Studies Index. décimale : PER Périodiques Résumé : The current study investigated longitudinal associations between parent-rated temperament, observed exuberance and accelerometer activity level at 18-months and symptoms of ASD and ADHD at 36-months in a sample of 54 children at elevated likelihood for ASD. For the specific parent-rated temperament scales, most observed significant associations appeared to be specific for either ASD or ADHD symptoms. Indeed, by controlling for overlapping symptoms a different pattern of associations emerged. These results illustrate how temperamental measures may signal risk for later ASD versus ADHD symptomatology in infants at elevated likelihood for ASD. In addition, they indicate the potential of adopting a broader view on neurodevelopmental disorders by investigating not only ASD traits, but also co-occurring disorders such as ADHD in samples of elevated likelihood for ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05001-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455
in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.995-1006[article] How Does Temperament in Toddlers at Elevated Likelihood for Autism Relate to Symptoms of Autism and ADHD at Three Years of Age? [Texte imprimé et/ou numérique] / L. A. KONKE, Auteur ; T. FORSLUND, Auteur ; E. NILSSON-JOBS, Auteur ; P. NYSTROM, Auteur ; T. FALCK-YTTER, Auteur ; Karin C. BROCKI, Auteur . - p.995-1006.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.995-1006
Mots-clés : Attention Deficit Disorder with Hyperactivity/diagnosis/epidemiology Autism Spectrum Disorder/diagnosis Autistic Disorder Child, Preschool Humans Infant Parents Temperament Attention-Deficit/Hyperactivity Disorder Autism Spectrum Disorder Infant Sibling Studies Index. décimale : PER Périodiques Résumé : The current study investigated longitudinal associations between parent-rated temperament, observed exuberance and accelerometer activity level at 18-months and symptoms of ASD and ADHD at 36-months in a sample of 54 children at elevated likelihood for ASD. For the specific parent-rated temperament scales, most observed significant associations appeared to be specific for either ASD or ADHD symptoms. Indeed, by controlling for overlapping symptoms a different pattern of associations emerged. These results illustrate how temperamental measures may signal risk for later ASD versus ADHD symptomatology in infants at elevated likelihood for ASD. In addition, they indicate the potential of adopting a broader view on neurodevelopmental disorders by investigating not only ASD traits, but also co-occurring disorders such as ADHD in samples of elevated likelihood for ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05001-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 Local and Global Visual Processing in 3-Year-Olds With and Without Autism / E. NILSSON JOBS in Journal of Autism and Developmental Disorders, 48-6 (June 2018)
PermalinkPreference for biological motion is reduced in ASD: implications for clinical trials and the search for biomarkers / L. MASON in Molecular Autism, 12 (2021)
PermalinkPreschool Staff Spot Social Communication Difficulties, But Not Restricted and Repetitive Behaviors in Young Autistic Children / E. NILSSON JOBS in Journal of Autism and Developmental Disorders, 49-5 (May 2019)
PermalinkReduced orienting to audiovisual synchrony in infancy predicts autism diagnosis at 3 years of age / T. FALCK-YTTER in Journal of Child Psychology and Psychiatry, 59-8 (August 2018)
PermalinkResponding to Other People's Direct Gaze: Alterations in Gaze Behavior in Infants at Risk for Autism Occur on Very Short Timescales / P. NYSTROM in Journal of Autism and Developmental Disorders, 47-11 (November 2017)
PermalinkSex Differences in Social Attention in Infants at Risk for Autism / J. L. KLEBERG in Journal of Autism and Developmental Disorders, 49-4 (April 2019)
PermalinkSpotting Signs of Autism in 3-Year-Olds: Comparing Information from Parents and Preschool Staff / E. NILSSON JOBS in Journal of Autism and Developmental Disorders, 49-3 (March 2019)
PermalinkUpdating Expectations About Unexpected Object Motion in Infants Later Diagnosed with Autism Spectrum Disorder / Sheila ACHERMANN in Journal of Autism and Developmental Disorders, 51-11 (November 2021)
PermalinkVisual Search Performance Does Not Relate to Autistic Traits in the General Population / D. LOPEZ PEREZ in Journal of Autism and Developmental Disorders, 49-6 (June 2019)
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