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Détail de l'auteur
Auteur J. M. ERIKSSON |
Documents disponibles écrits par cet auteur (2)
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Effect of co-twin gender on neurodevelopmental symptoms: a twin register study / J. M. ERIKSSON in Molecular Autism, 7 (2016)
[article]
Titre : Effect of co-twin gender on neurodevelopmental symptoms: a twin register study Type de document : Texte imprimé et/ou numérique Auteurs : J. M. ERIKSSON, Auteur ; S. LUNDSTRÖM, Auteur ; P. LICHTENSTEIN, Auteur ; Susanne BEJEROT, Auteur ; E. ERIKSSON, Auteur Article en page(s) : 8p. Langues : Anglais (eng) Mots-clés : Attention Deficit Disorder with Hyperactivity/genetics/physiopathology Autism Spectrum Disorder/genetics/physiopathology Child Comorbidity Diseases in Twins Female Follow-Up Studies Gender Identity Humans Interview, Psychological Male Neurodevelopmental Disorders/genetics/physiopathology Parents Pregnancy Prenatal Exposure Delayed Effects Sex Characteristics Stereotyped Behavior Sweden/epidemiology Testosterone/physiology Tic Disorders/genetics/physiopathology Twins, Dizygotic/psychology Asperger syndrome Attention-deficit hyperactivity disorders Autistic disorder Symptom assessment Twin study Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders thought to have both genetic and environmental causes. It has been hypothesized that exposure to elevated levels of prenatal testosterone is associated with elevated traits of ASD and ADHD. Assuming that testosterone levels from a dizygotic male twin fetus may lead to enhanced testosterone exposure of its co-twins, we aimed to test the prenatal testosterone hypothesis by comparing same-sex with opposite-sex dizygotic twins with respect to neurodevelopmental symptoms. METHODS: Neuropsychiatric traits were assessed in a population-based twin cohort from the Child and Adolescent Twin Study in Sweden (CATSS). Parental interviews were conducted for 16,312 dizygotic twins, 9 and 12 years old, with the Autism-Tics, ADHD, and other Comorbidities inventory (A-TAC). RESULTS: Girls with a female co-twin had an increased risk of reaching the cut-off score for ADHD compared with girls with a male co-twin. Both boys and girls with a female co-twin displayed a larger number of traits related to attention deficit and repetitive and stereotyped behaviors than those with a male twin. In girls, this also extended to social interaction and the combined measures for ASD and ADHD, however, with small effect sizes. CONCLUSIONS: Our results are reverse to what would have been expected from the prenatal testosterone hypothesis but consistent with a previous study of ASD and ADHD traits in dizygotic twins. The seemingly protective effect for girls of having a twin brother may be an effect of parent report bias, but may also be an unexpected effect of sharing the intrauterine environment with a male co-twin. En ligne : http://dx.doi.org/10.1186/s13229-016-0074-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328
in Molecular Autism > 7 (2016) . - 8p.[article] Effect of co-twin gender on neurodevelopmental symptoms: a twin register study [Texte imprimé et/ou numérique] / J. M. ERIKSSON, Auteur ; S. LUNDSTRÖM, Auteur ; P. LICHTENSTEIN, Auteur ; Susanne BEJEROT, Auteur ; E. ERIKSSON, Auteur . - 8p.
Langues : Anglais (eng)
in Molecular Autism > 7 (2016) . - 8p.
Mots-clés : Attention Deficit Disorder with Hyperactivity/genetics/physiopathology Autism Spectrum Disorder/genetics/physiopathology Child Comorbidity Diseases in Twins Female Follow-Up Studies Gender Identity Humans Interview, Psychological Male Neurodevelopmental Disorders/genetics/physiopathology Parents Pregnancy Prenatal Exposure Delayed Effects Sex Characteristics Stereotyped Behavior Sweden/epidemiology Testosterone/physiology Tic Disorders/genetics/physiopathology Twins, Dizygotic/psychology Asperger syndrome Attention-deficit hyperactivity disorders Autistic disorder Symptom assessment Twin study Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders thought to have both genetic and environmental causes. It has been hypothesized that exposure to elevated levels of prenatal testosterone is associated with elevated traits of ASD and ADHD. Assuming that testosterone levels from a dizygotic male twin fetus may lead to enhanced testosterone exposure of its co-twins, we aimed to test the prenatal testosterone hypothesis by comparing same-sex with opposite-sex dizygotic twins with respect to neurodevelopmental symptoms. METHODS: Neuropsychiatric traits were assessed in a population-based twin cohort from the Child and Adolescent Twin Study in Sweden (CATSS). Parental interviews were conducted for 16,312 dizygotic twins, 9 and 12 years old, with the Autism-Tics, ADHD, and other Comorbidities inventory (A-TAC). RESULTS: Girls with a female co-twin had an increased risk of reaching the cut-off score for ADHD compared with girls with a male co-twin. Both boys and girls with a female co-twin displayed a larger number of traits related to attention deficit and repetitive and stereotyped behaviors than those with a male twin. In girls, this also extended to social interaction and the combined measures for ASD and ADHD, however, with small effect sizes. CONCLUSIONS: Our results are reverse to what would have been expected from the prenatal testosterone hypothesis but consistent with a previous study of ASD and ADHD traits in dizygotic twins. The seemingly protective effect for girls of having a twin brother may be an effect of parent report bias, but may also be an unexpected effect of sharing the intrauterine environment with a male co-twin. En ligne : http://dx.doi.org/10.1186/s13229-016-0074-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328 Minor physical anomalies in adults with autism spectrum disorder and healthy controls / I. MANOUILENKO in Autism Research and Treatment, 2014 (2014)
[article]
Titre : Minor physical anomalies in adults with autism spectrum disorder and healthy controls Type de document : Texte imprimé et/ou numérique Auteurs : I. MANOUILENKO, Auteur ; J. M. ERIKSSON, Auteur ; M. B. HUMBLE, Auteur ; Susanne BEJEROT, Auteur Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Minor Physical Anomalies (MPAs) are subtle abnormalities of the head, face, and limbs, without significant cosmetic or functional impact to the individual. They are assumed to represent external markers of developmental deviations during foetal life. MPAs have been suggested to indicate severity in mental illness and constitute external markers for atypical brain development. Higher frequencies of MPAs can be found in children with autism. The aims of the present study were to examine the prevalence and patterns of MPAs in adults with autism spectrum disorder (ASD) and to investigate whether MPAs are associated with symptom severity and overall functioning. Fifty adults with ASD and intelligence within the normal range and 53 healthy controls were examined with the Waldrop scale, an instrument for assessing MPAs. Face and feet were photographed enabling blinded assessment. Significant differences between the ASD and the control group were found on the MPA total scores, and also in the craniofacial region scores. Moreover, the shape of the ears was associated with autistic traits, in the ASD group. High MPA total scores were associated with poorer functioning. The findings suggest a link between MPAs, autistic traits, and level of functioning. Assessment of MPAs may assist in the diagnostic procedure of psychiatric disorders. En ligne : http://dx.doi.org/10.1155/2014/743482 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=332
in Autism Research and Treatment > 2014 (2014)[article] Minor physical anomalies in adults with autism spectrum disorder and healthy controls [Texte imprimé et/ou numérique] / I. MANOUILENKO, Auteur ; J. M. ERIKSSON, Auteur ; M. B. HUMBLE, Auteur ; Susanne BEJEROT, Auteur.
Langues : Anglais (eng)
in Autism Research and Treatment > 2014 (2014)
Index. décimale : PER Périodiques Résumé : Minor Physical Anomalies (MPAs) are subtle abnormalities of the head, face, and limbs, without significant cosmetic or functional impact to the individual. They are assumed to represent external markers of developmental deviations during foetal life. MPAs have been suggested to indicate severity in mental illness and constitute external markers for atypical brain development. Higher frequencies of MPAs can be found in children with autism. The aims of the present study were to examine the prevalence and patterns of MPAs in adults with autism spectrum disorder (ASD) and to investigate whether MPAs are associated with symptom severity and overall functioning. Fifty adults with ASD and intelligence within the normal range and 53 healthy controls were examined with the Waldrop scale, an instrument for assessing MPAs. Face and feet were photographed enabling blinded assessment. Significant differences between the ASD and the control group were found on the MPA total scores, and also in the craniofacial region scores. Moreover, the shape of the ears was associated with autistic traits, in the ASD group. High MPA total scores were associated with poorer functioning. The findings suggest a link between MPAs, autistic traits, and level of functioning. Assessment of MPAs may assist in the diagnostic procedure of psychiatric disorders. En ligne : http://dx.doi.org/10.1155/2014/743482 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=332