Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur L. CORDEIRO |
Documents disponibles écrits par cet auteur (1)
Faire une suggestion Affiner la recherche
Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization / L. CORDEIRO in Journal of Neurodevelopmental Disorders, 3-1 (March 2011)
[article]
Titre : Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization Type de document : Texte imprimé et/ou numérique Auteurs : L. CORDEIRO, Auteur ; Elizabeth C. BALLINGER, Auteur ; Randi J. HAGERMAN, Auteur ; D. HESSL, Auteur Article en page(s) : p.57-67 Langues : Anglais (eng) Mots-clés : Anxiety Fragile X syndrome Intellectual disability Social phobia Specific phobia Index. décimale : PER Périodiques Résumé : Fragile X syndrome (FXS) is the most common form of inherited intellectual disability (ID). Anxiety and social withdrawal are considered core features of the FXS phenotype, yet there is limited diagnostic evidence of the prevalence of formal anxiety disorders in FXS. This study assessed the prevalence of anxiety disorders in a sample of 58 males and 39 females with FXS (ages 5.0-33.3 years). Participants' parents completed the Anxiety Disorders Interview Schedule (ADIS-IV), a clinical interview based on DSM-IV criteria, and the Anxiety Depression and Mood Scale (ADAMS), a psychiatric disorders screening instrument normed in ID. We conducted cognitive (IQ) and autism (AUT) assessments and surveyed medication use. Despite a high rate of psychopharmacological treatment, 86.2% of males and 76.9% of females met criteria for an anxiety disorder, with social phobia and specific phobia the most commonly diagnosed. Proband status, gender, and IQ were not significantly related to any anxiety disorders, however significantly higher rates of a few anxiety disorders were found in older age and AUT groups. Significant correlations between ADIS diagnoses and ADAMS scores provided cross-validation of instruments, indicating that the ADIS is suitable for use in FXS. A greater percentage of our sample met criteria for most anxiety disorders than has been reported in other ID groups or the general population. The rate of anxiety compared to general ID suggests that the FMR1 full mutation confers an especially high risk for these disorders, regardless of factors commonly associated with FXS clinical involvement. A thorough clinical assessment and treatment of anxiety should be included in the FXS standard of care. En ligne : http://dx.doi.org/10.1007/s11689-010-9067-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=343
in Journal of Neurodevelopmental Disorders > 3-1 (March 2011) . - p.57-67[article] Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization [Texte imprimé et/ou numérique] / L. CORDEIRO, Auteur ; Elizabeth C. BALLINGER, Auteur ; Randi J. HAGERMAN, Auteur ; D. HESSL, Auteur . - p.57-67.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 3-1 (March 2011) . - p.57-67
Mots-clés : Anxiety Fragile X syndrome Intellectual disability Social phobia Specific phobia Index. décimale : PER Périodiques Résumé : Fragile X syndrome (FXS) is the most common form of inherited intellectual disability (ID). Anxiety and social withdrawal are considered core features of the FXS phenotype, yet there is limited diagnostic evidence of the prevalence of formal anxiety disorders in FXS. This study assessed the prevalence of anxiety disorders in a sample of 58 males and 39 females with FXS (ages 5.0-33.3 years). Participants' parents completed the Anxiety Disorders Interview Schedule (ADIS-IV), a clinical interview based on DSM-IV criteria, and the Anxiety Depression and Mood Scale (ADAMS), a psychiatric disorders screening instrument normed in ID. We conducted cognitive (IQ) and autism (AUT) assessments and surveyed medication use. Despite a high rate of psychopharmacological treatment, 86.2% of males and 76.9% of females met criteria for an anxiety disorder, with social phobia and specific phobia the most commonly diagnosed. Proband status, gender, and IQ were not significantly related to any anxiety disorders, however significantly higher rates of a few anxiety disorders were found in older age and AUT groups. Significant correlations between ADIS diagnoses and ADAMS scores provided cross-validation of instruments, indicating that the ADIS is suitable for use in FXS. A greater percentage of our sample met criteria for most anxiety disorders than has been reported in other ID groups or the general population. The rate of anxiety compared to general ID suggests that the FMR1 full mutation confers an especially high risk for these disorders, regardless of factors commonly associated with FXS clinical involvement. A thorough clinical assessment and treatment of anxiety should be included in the FXS standard of care. En ligne : http://dx.doi.org/10.1007/s11689-010-9067-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=343