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Détail de l'auteur
Auteur Z. ZHENG |
Documents disponibles écrits par cet auteur (2)
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Association between schizophrenia and autism spectrum disorder: A systematic review and meta-analysis / Z. ZHENG in Autism Research, 11-8 (August 2018)
[article]
Titre : Association between schizophrenia and autism spectrum disorder: A systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Z. ZHENG, Auteur ; P. ZHENG, Auteur ; X. ZOU, Auteur Article en page(s) : p.1110-1119 Langues : Anglais (eng) Mots-clés : association autism spectrum disorder meta-analysis schizophrenia Index. décimale : PER Périodiques Résumé : Schizophrenia and autism spectrum disorder (ASD) are significant public health problems. Scientists have recently explored the association between schizophrenia and ASD, but the findings are inconsistent. Thus, we conducted a systematic review and meta-analysis of epidemiological studies to examine the association between schizophrenia and ASD. PubMed, Embase, and the Cochrane Library were used for literature searches to identify eligible studies published in English before October 2, 2017. Relevant studies estimating the association between schizophrenia and ASD were included. The meta-analysis of the prevalence of schizophrenia in individuals with ASD encompassed 1,950,113 participants and 14,945 individuals with ASD. A random-effects model was chosen to synthesize the effect sizes of individual studies. The prevalence of schizophrenia was significantly higher in individuals with ASD than in controls (odds ratio = 3.55, 95% confidence interval: 2.08-6.05, P < .001). Both sensitivity analysis and publication bias testing revealed that the findings were robust. The systematic review of the prevalence of ASD in individuals with schizophrenia encompassed 930 participants. The prevalence of ASD in individuals with schizophrenia ranged from 3.4 to 52%. The systematic review and meta-analysis showed a significant association between schizophrenia and ASD. Autism Research 2018, 11: 1110-1119. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This systematic review and meta-analysis explored the association between schizophrenia and ASD. We found that the prevalence of schizophrenia was significantly higher in individuals with ASD than in controls and the prevalence of ASD in individuals with schizophrenia ranged from 3.4 to 52%. A comprehensive estimation of schizophrenia and ASD has important implications for the diagnosis, treatment, prognosis, and development of a fundamental understanding of these disorders. En ligne : http://dx.doi.org/10.1002/aur.1977 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369
in Autism Research > 11-8 (August 2018) . - p.1110-1119[article] Association between schizophrenia and autism spectrum disorder: A systematic review and meta-analysis [Texte imprimé et/ou numérique] / Z. ZHENG, Auteur ; P. ZHENG, Auteur ; X. ZOU, Auteur . - p.1110-1119.
Langues : Anglais (eng)
in Autism Research > 11-8 (August 2018) . - p.1110-1119
Mots-clés : association autism spectrum disorder meta-analysis schizophrenia Index. décimale : PER Périodiques Résumé : Schizophrenia and autism spectrum disorder (ASD) are significant public health problems. Scientists have recently explored the association between schizophrenia and ASD, but the findings are inconsistent. Thus, we conducted a systematic review and meta-analysis of epidemiological studies to examine the association between schizophrenia and ASD. PubMed, Embase, and the Cochrane Library were used for literature searches to identify eligible studies published in English before October 2, 2017. Relevant studies estimating the association between schizophrenia and ASD were included. The meta-analysis of the prevalence of schizophrenia in individuals with ASD encompassed 1,950,113 participants and 14,945 individuals with ASD. A random-effects model was chosen to synthesize the effect sizes of individual studies. The prevalence of schizophrenia was significantly higher in individuals with ASD than in controls (odds ratio = 3.55, 95% confidence interval: 2.08-6.05, P < .001). Both sensitivity analysis and publication bias testing revealed that the findings were robust. The systematic review of the prevalence of ASD in individuals with schizophrenia encompassed 930 participants. The prevalence of ASD in individuals with schizophrenia ranged from 3.4 to 52%. The systematic review and meta-analysis showed a significant association between schizophrenia and ASD. Autism Research 2018, 11: 1110-1119. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This systematic review and meta-analysis explored the association between schizophrenia and ASD. We found that the prevalence of schizophrenia was significantly higher in individuals with ASD than in controls and the prevalence of ASD in individuals with schizophrenia ranged from 3.4 to 52%. A comprehensive estimation of schizophrenia and ASD has important implications for the diagnosis, treatment, prognosis, and development of a fundamental understanding of these disorders. En ligne : http://dx.doi.org/10.1002/aur.1977 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 Peripheral Blood S100B Levels in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis / Z. ZHENG in Journal of Autism and Developmental Disorders, 51-8 (August 2021)
[article]
Titre : Peripheral Blood S100B Levels in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis Type de document : Texte imprimé et/ou numérique Auteurs : Z. ZHENG, Auteur ; P. ZHENG, Auteur ; X. ZOU, Auteur Article en page(s) : p.2569-2577 Langues : Anglais (eng) Mots-clés : Adolescent Autism Spectrum Disorder/blood Biomarkers Child Child, Preschool Female Humans Male S100 Calcium Binding Protein beta Subunit/blood Autism spectrum disorder Blood Meta-analysis S100b Index. décimale : PER Périodiques Résumé : The S100 calcium-binding protein beta subunit (S100B) protein, which mostly exists in the central nervous system, is commonly noted as a marker of neuronal damage. We conducted the first systematic review with meta-analysis to compare peripheral blood S100B levels in individuals with ASD with those in healthy controls. A systematic search was carried out for studies published before May 5, 2020. In total, this meta-analysis involved ten studies with 822 participants and 451 cases. The meta-analysis revealed that individuals with ASD had higher peripheral blood S100B levels than healthy controls [standardized mean difference (SMD)?=?0.97, 95% confidence interval (95% CI)?=?0.41-1.53; p?0.001]. Peripheral blood S100B levels may have potential as a useful biomarker for ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04710-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452
in Journal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2569-2577[article] Peripheral Blood S100B Levels in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis [Texte imprimé et/ou numérique] / Z. ZHENG, Auteur ; P. ZHENG, Auteur ; X. ZOU, Auteur . - p.2569-2577.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2569-2577
Mots-clés : Adolescent Autism Spectrum Disorder/blood Biomarkers Child Child, Preschool Female Humans Male S100 Calcium Binding Protein beta Subunit/blood Autism spectrum disorder Blood Meta-analysis S100b Index. décimale : PER Périodiques Résumé : The S100 calcium-binding protein beta subunit (S100B) protein, which mostly exists in the central nervous system, is commonly noted as a marker of neuronal damage. We conducted the first systematic review with meta-analysis to compare peripheral blood S100B levels in individuals with ASD with those in healthy controls. A systematic search was carried out for studies published before May 5, 2020. In total, this meta-analysis involved ten studies with 822 participants and 451 cases. The meta-analysis revealed that individuals with ASD had higher peripheral blood S100B levels than healthy controls [standardized mean difference (SMD)?=?0.97, 95% confidence interval (95% CI)?=?0.41-1.53; p?0.001]. Peripheral blood S100B levels may have potential as a useful biomarker for ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04710-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452