Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur B. JO |
Documents disponibles écrits par cet auteur (2)
Faire une suggestion Affiner la recherche
Effects of X Chromosome Monosomy and Genomic Imprinting on Observational Markers of Social Anxiety in Prepubertal Girls with Turner Syndrome / S. S. HALL in Journal of Autism and Developmental Disorders, 52-1 (January 2022)
[article]
Titre : Effects of X Chromosome Monosomy and Genomic Imprinting on Observational Markers of Social Anxiety in Prepubertal Girls with Turner Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : S. S. HALL, Auteur ; M. J. RILEY, Auteur ; R. N. WESTON, Auteur ; J. F. LEPAGE, Auteur ; D. S. HONG, Auteur ; B. JO, Auteur ; J. HALLMAYER, Auteur ; A. L. REISS, Auteur Article en page(s) : p.16-27 Langues : Anglais (eng) Mots-clés : Anxiety Autism Spectrum Disorder Female Genomic Imprinting Humans Monosomy Turner Syndrome/genetics X Chromosome Behavioral observations Gaze avoidance Turner syndrome Index. décimale : PER Périodiques Résumé : Previous studies have suggested that girls with Turner syndrome (TS) exhibit symptoms of social anxiety during interactions with others. However, few studies have quantified these behaviors during naturalistic face-to-face social encounters. In this study, we coded observational markers of social anxiety in prepubertal girls with TS and age-matched controls during a 10-min social encounter with an unfamiliar examiner. Results showed that girls with TS exhibited significantly higher levels of gaze avoidance compared to controls. Impairments in social gaze were particularly increased in girls with a maternally retained X chromosome (Xm), suggesting a genomic imprinting effect. These data indicate that social gaze avoidance may be a critical behavioral marker for identifying early social dysfunction in young girls with TS. En ligne : http://dx.doi.org/10.1007/s10803-021-04896-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454
in Journal of Autism and Developmental Disorders > 52-1 (January 2022) . - p.16-27[article] Effects of X Chromosome Monosomy and Genomic Imprinting on Observational Markers of Social Anxiety in Prepubertal Girls with Turner Syndrome [Texte imprimé et/ou numérique] / S. S. HALL, Auteur ; M. J. RILEY, Auteur ; R. N. WESTON, Auteur ; J. F. LEPAGE, Auteur ; D. S. HONG, Auteur ; B. JO, Auteur ; J. HALLMAYER, Auteur ; A. L. REISS, Auteur . - p.16-27.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-1 (January 2022) . - p.16-27
Mots-clés : Anxiety Autism Spectrum Disorder Female Genomic Imprinting Humans Monosomy Turner Syndrome/genetics X Chromosome Behavioral observations Gaze avoidance Turner syndrome Index. décimale : PER Périodiques Résumé : Previous studies have suggested that girls with Turner syndrome (TS) exhibit symptoms of social anxiety during interactions with others. However, few studies have quantified these behaviors during naturalistic face-to-face social encounters. In this study, we coded observational markers of social anxiety in prepubertal girls with TS and age-matched controls during a 10-min social encounter with an unfamiliar examiner. Results showed that girls with TS exhibited significantly higher levels of gaze avoidance compared to controls. Impairments in social gaze were particularly increased in girls with a maternally retained X chromosome (Xm), suggesting a genomic imprinting effect. These data indicate that social gaze avoidance may be a critical behavioral marker for identifying early social dysfunction in young girls with TS. En ligne : http://dx.doi.org/10.1007/s10803-021-04896-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures / M. ULJAREVIC in Molecular Autism, 12 (2021)
[article]
Titre : Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures Type de document : Texte imprimé et/ou numérique Auteurs : M. ULJAREVIC, Auteur ; B. JO, Auteur ; T. W. FRAZIER, Auteur ; Lawrence SCAHILL, Auteur ; Eric A. YOUNGSTROM, Auteur ; A. Y. HARDAN, Auteur Article en page(s) : 39 p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Circumscribed interest Factor analysis Insistence of sameness Repetitive motor behavior Index. décimale : PER Périodiques Résumé : BACKGROUND: Restricted and repetitive behaviors (RRB) in autism spectrum disorder (ASD) encompass several distinct domains. However, commonly used general ASD measures provide broad RRB scores rather than assessing separate RRB domains. The main objective of the current investigation was to conduct a psychometric evaluation of the ability of the Social Responsiveness Scale (SRS-2), the Social Communication Questionnaire (SCQ), the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS) to capture different RRB constructs. METHODS: Exploratory Structural Equation Modeling (ESEM) was conducted using individual item-level data from the SRS-2, SCQ, ADI-R and the ADOS. Data were obtained from five existing publicly available databases. For the SRS-2, the final sample consisted of N?=?16,761 individuals (M(age)?=?9.43, SD?=?3.73; 18.5% female); for the SCQ, of N?=?15,840 (M(age)?=?7.99, SD?=?4.06; 18.1% female); for the ADI-R, of N?=?8985 (M(age)?=?8.86, SD?=?4.68; 19.4% female); and for the ADOS, of N?=?6314 (M(age)?=?12.29, SD?=?6.79; 17.7% female). RESULTS: The three-factor structure provided the most optimal and interpretable fit to data for all measures (comparative fit index???.983, Tucker Lewis index???.966, root mean square error of approximation???.028). Repetitive-motor behaviors, insistence on sameness and unusual or circumscribed interests factors emerged across all instruments. No acceptable fit was identified for the ADOS. LIMITATIONS: The five datasets used here afforded a large as well as wide distribution of the RRB item scores. However, measures used for establishing convergent and divergent validity were only available for a portion of the sample. CONCLUSIONS: Reported findings offer promise for capturing important RRB domains using general ASD measures and highlight the need for measurement development. En ligne : http://dx.doi.org/10.1186/s13229-021-00419-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459
in Molecular Autism > 12 (2021) . - 39 p.[article] Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures [Texte imprimé et/ou numérique] / M. ULJAREVIC, Auteur ; B. JO, Auteur ; T. W. FRAZIER, Auteur ; Lawrence SCAHILL, Auteur ; Eric A. YOUNGSTROM, Auteur ; A. Y. HARDAN, Auteur . - 39 p.
Langues : Anglais (eng)
in Molecular Autism > 12 (2021) . - 39 p.
Mots-clés : Autism spectrum disorder Circumscribed interest Factor analysis Insistence of sameness Repetitive motor behavior Index. décimale : PER Périodiques Résumé : BACKGROUND: Restricted and repetitive behaviors (RRB) in autism spectrum disorder (ASD) encompass several distinct domains. However, commonly used general ASD measures provide broad RRB scores rather than assessing separate RRB domains. The main objective of the current investigation was to conduct a psychometric evaluation of the ability of the Social Responsiveness Scale (SRS-2), the Social Communication Questionnaire (SCQ), the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS) to capture different RRB constructs. METHODS: Exploratory Structural Equation Modeling (ESEM) was conducted using individual item-level data from the SRS-2, SCQ, ADI-R and the ADOS. Data were obtained from five existing publicly available databases. For the SRS-2, the final sample consisted of N?=?16,761 individuals (M(age)?=?9.43, SD?=?3.73; 18.5% female); for the SCQ, of N?=?15,840 (M(age)?=?7.99, SD?=?4.06; 18.1% female); for the ADI-R, of N?=?8985 (M(age)?=?8.86, SD?=?4.68; 19.4% female); and for the ADOS, of N?=?6314 (M(age)?=?12.29, SD?=?6.79; 17.7% female). RESULTS: The three-factor structure provided the most optimal and interpretable fit to data for all measures (comparative fit index???.983, Tucker Lewis index???.966, root mean square error of approximation???.028). Repetitive-motor behaviors, insistence on sameness and unusual or circumscribed interests factors emerged across all instruments. No acceptable fit was identified for the ADOS. LIMITATIONS: The five datasets used here afforded a large as well as wide distribution of the RRB item scores. However, measures used for establishing convergent and divergent validity were only available for a portion of the sample. CONCLUSIONS: Reported findings offer promise for capturing important RRB domains using general ASD measures and highlight the need for measurement development. En ligne : http://dx.doi.org/10.1186/s13229-021-00419-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459