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Auteur Goldie A. MCQUAID |
Documents disponibles écrits par cet auteur (11)
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Cardiovascular disease risk factors in autistic adults: The impact of sleep quality and antipsychotic medication use / Lauren BISHOP in Autism Research, 16-3 (March 2023)
[article]
Titre : Cardiovascular disease risk factors in autistic adults: The impact of sleep quality and antipsychotic medication use Type de document : Texte imprimé et/ou numérique Auteurs : Lauren BISHOP, Auteur ; Rebecca A. CHARLTON, Auteur ; Kiley J. MCLEAN, Auteur ; Goldie A. MCQUAID, Auteur ; Nancy Raitano LEE, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : p.569-579 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Approximately 40% of American adults are affected by cardiovascular disease (CVD) risk factors (e.g., high blood pressure, high cholesterol, diabetes, and overweight or obesity), and risk among autistic adults may be even higher. Mechanisms underlying the high prevalence of CVD risk factors in autistic people may include known correlates of CVD risk factors in other groups, including high levels of perceived stress, poor sleep quality, and antipsychotic medication use. A sample of 545 autistic adults without intellectual disability aged 18+ were recruited through the Simons Foundation Powering Autism Research, Research Match. Multiple linear regression models examined the association between key independent variables (self-reported perceived stress, sleep quality, and antipsychotic medication use) and CVD risk factors, controlling for demographic variables (age, sex assigned at birth, race, low-income status, autistic traits). Overall, 73.2% of autistic adults in our sample had an overweight/obesity classification, 45.3% had high cholesterol, 39.4% had high blood pressure, and 10.3% had diabetes. Older age, male sex assigned at birth, and poorer sleep quality were associated with a higher number of CVD risk factors. Using antipsychotic medications was associated with an increased likelihood of having diabetes. Poorer sleep quality was associated with an increased likelihood of having an overweight/obesity classification. Self-reported CVD risk factors are highly prevalent among autistic adults. Both improving sleep quality and closely monitoring CVD risk factors among autistic adults who use antipsychotic medications have the potential to reduce risk for CVD. En ligne : https://doi.org/10.1002/aur.2872 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498
in Autism Research > 16-3 (March 2023) . - p.569-579[article] Cardiovascular disease risk factors in autistic adults: The impact of sleep quality and antipsychotic medication use [Texte imprimé et/ou numérique] / Lauren BISHOP, Auteur ; Rebecca A. CHARLTON, Auteur ; Kiley J. MCLEAN, Auteur ; Goldie A. MCQUAID, Auteur ; Nancy Raitano LEE, Auteur ; Gregory L. WALLACE, Auteur . - p.569-579.
Langues : Anglais (eng)
in Autism Research > 16-3 (March 2023) . - p.569-579
Index. décimale : PER Périodiques Résumé : Abstract Approximately 40% of American adults are affected by cardiovascular disease (CVD) risk factors (e.g., high blood pressure, high cholesterol, diabetes, and overweight or obesity), and risk among autistic adults may be even higher. Mechanisms underlying the high prevalence of CVD risk factors in autistic people may include known correlates of CVD risk factors in other groups, including high levels of perceived stress, poor sleep quality, and antipsychotic medication use. A sample of 545 autistic adults without intellectual disability aged 18+ were recruited through the Simons Foundation Powering Autism Research, Research Match. Multiple linear regression models examined the association between key independent variables (self-reported perceived stress, sleep quality, and antipsychotic medication use) and CVD risk factors, controlling for demographic variables (age, sex assigned at birth, race, low-income status, autistic traits). Overall, 73.2% of autistic adults in our sample had an overweight/obesity classification, 45.3% had high cholesterol, 39.4% had high blood pressure, and 10.3% had diabetes. Older age, male sex assigned at birth, and poorer sleep quality were associated with a higher number of CVD risk factors. Using antipsychotic medications was associated with an increased likelihood of having diabetes. Poorer sleep quality was associated with an increased likelihood of having an overweight/obesity classification. Self-reported CVD risk factors are highly prevalent among autistic adults. Both improving sleep quality and closely monitoring CVD risk factors among autistic adults who use antipsychotic medications have the potential to reduce risk for CVD. En ligne : https://doi.org/10.1002/aur.2872 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498 Cardiovascular risk and emotion regulation contribute to depression symptomatology in middle-aged and older autistic adults / Rebecca A. CHARLTON in Research in Autism Spectrum Disorders, 101 (March 2023)
[article]
Titre : Cardiovascular risk and emotion regulation contribute to depression symptomatology in middle-aged and older autistic adults Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca A. CHARLTON, Auteur ; Goldie A. MCQUAID, Auteur ; Lauren BISHOP, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : 102089 Langues : Anglais (eng) Mots-clés : Ageing Autism Cardiovascular risk factors Depression Emotion regulation Later-life Physical health Index. décimale : PER Périodiques Résumé : Background Cardiovascular risk factors (CVRF) and executive function difficulties increase during later-life and are associated with depression symptoms among non-autistic older people. These associations, however, have not yet been explored among middle-aged and older autistic people. Methods Using data collected via Simons Foundation Powering Autism Research (SPARK), Research Match, we examined the frequency of CVRF, and associations between CVRF, executive function and depression symptoms in 387 middle-aged and older autistic people (aged 40 “83 years). Results Autistic adults reported high rates of CVRF (two, 28.9%; three or more, 23.2%). Rates of high cholesterol and obesity were greater among middle-aged and older autistic adults compared to the general population. CVRF, age, and emotion regulation (but not inhibitory control), were significantly associated with depression symptoms in middle-aged and older autistic adults. Conclusions CVRF occur at high rates in middle-aged and older autistic adults, and it is important that healthcare providers monitor risk factors in order to implement preventative strategies. CVRF are associated with depressive symptoms among middle-aged and older autistic adults, but may not be as important as difficulties with emotion regulation. En ligne : https://doi.org/10.1016/j.rasd.2022.102089 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492
in Research in Autism Spectrum Disorders > 101 (March 2023) . - 102089[article] Cardiovascular risk and emotion regulation contribute to depression symptomatology in middle-aged and older autistic adults [Texte imprimé et/ou numérique] / Rebecca A. CHARLTON, Auteur ; Goldie A. MCQUAID, Auteur ; Lauren BISHOP, Auteur ; Gregory L. WALLACE, Auteur . - 102089.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 101 (March 2023) . - 102089
Mots-clés : Ageing Autism Cardiovascular risk factors Depression Emotion regulation Later-life Physical health Index. décimale : PER Périodiques Résumé : Background Cardiovascular risk factors (CVRF) and executive function difficulties increase during later-life and are associated with depression symptoms among non-autistic older people. These associations, however, have not yet been explored among middle-aged and older autistic people. Methods Using data collected via Simons Foundation Powering Autism Research (SPARK), Research Match, we examined the frequency of CVRF, and associations between CVRF, executive function and depression symptoms in 387 middle-aged and older autistic people (aged 40 “83 years). Results Autistic adults reported high rates of CVRF (two, 28.9%; three or more, 23.2%). Rates of high cholesterol and obesity were greater among middle-aged and older autistic adults compared to the general population. CVRF, age, and emotion regulation (but not inhibitory control), were significantly associated with depression symptoms in middle-aged and older autistic adults. Conclusions CVRF occur at high rates in middle-aged and older autistic adults, and it is important that healthcare providers monitor risk factors in order to implement preventative strategies. CVRF are associated with depressive symptoms among middle-aged and older autistic adults, but may not be as important as difficulties with emotion regulation. En ligne : https://doi.org/10.1016/j.rasd.2022.102089 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492 Co-occurring ADHD symptoms in autistic adults are associated with less independence in daily living activities and lower subjective quality of life / Benjamin E. YERYS in Autism, 26-8 (November 2022)
[article]
Titre : Co-occurring ADHD symptoms in autistic adults are associated with less independence in daily living activities and lower subjective quality of life Type de document : Texte imprimé et/ou numérique Auteurs : Benjamin E. YERYS, Auteur ; Goldie A. MCQUAID, Auteur ; Nancy Raitano LEE, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : p.2188-2195 Langues : Anglais (eng) Mots-clés : Adult Humans Female Male Attention Deficit Disorder with Hyperactivity/complications/epidemiology/diagnosis Autistic Disorder/complications/epidemiology/diagnosis Activities of Daily Living/psychology Quality of Life Autism Spectrum Disorder/complications/epidemiology/diagnosis attention-deficit/hyperactivity disorder autism daily living skills Index. décimale : PER Périodiques Résumé : Outcomes for autistic adults are generally poor, including activities of daily living and self-ratings of quality of life. Co-occurring psychiatric conditions contribute to these poor outcomes. Attention-deficit/hyperactivity disorder is one of the most common co-occurring conditions in autistic individuals. However, we know little about the association between attention-deficit/hyperactivity disorder symptoms and outcomes in autistic adults. A total of 724 autistic adults (18-83 years; 58% female) recruited from the Simons Foundation Powering Autism Research participant registry completed questionnaires on demographics, co-occurring psychiatric conditions, activities of daily living, and subjective quality of life. Autistic adults who rated themselves as having more attention-deficit/hyperactivity disorder symptoms also rated themselves as having less independence in activities of daily living and a lower quality of life. This is the first study to show these relationships in autistic adults. These findings highlight that additional research and better supports for co-occurring attention-deficit/hyperactivity disorder symptoms may be critical to improving independence and quality of life for autistic adults. En ligne : http://dx.doi.org/10.1177/13623613221112198 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism > 26-8 (November 2022) . - p.2188-2195[article] Co-occurring ADHD symptoms in autistic adults are associated with less independence in daily living activities and lower subjective quality of life [Texte imprimé et/ou numérique] / Benjamin E. YERYS, Auteur ; Goldie A. MCQUAID, Auteur ; Nancy Raitano LEE, Auteur ; Gregory L. WALLACE, Auteur . - p.2188-2195.
Langues : Anglais (eng)
in Autism > 26-8 (November 2022) . - p.2188-2195
Mots-clés : Adult Humans Female Male Attention Deficit Disorder with Hyperactivity/complications/epidemiology/diagnosis Autistic Disorder/complications/epidemiology/diagnosis Activities of Daily Living/psychology Quality of Life Autism Spectrum Disorder/complications/epidemiology/diagnosis attention-deficit/hyperactivity disorder autism daily living skills Index. décimale : PER Périodiques Résumé : Outcomes for autistic adults are generally poor, including activities of daily living and self-ratings of quality of life. Co-occurring psychiatric conditions contribute to these poor outcomes. Attention-deficit/hyperactivity disorder is one of the most common co-occurring conditions in autistic individuals. However, we know little about the association between attention-deficit/hyperactivity disorder symptoms and outcomes in autistic adults. A total of 724 autistic adults (18-83 years; 58% female) recruited from the Simons Foundation Powering Autism Research participant registry completed questionnaires on demographics, co-occurring psychiatric conditions, activities of daily living, and subjective quality of life. Autistic adults who rated themselves as having more attention-deficit/hyperactivity disorder symptoms also rated themselves as having less independence in activities of daily living and a lower quality of life. This is the first study to show these relationships in autistic adults. These findings highlight that additional research and better supports for co-occurring attention-deficit/hyperactivity disorder symptoms may be critical to improving independence and quality of life for autistic adults. En ligne : http://dx.doi.org/10.1177/13623613221112198 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Increased perceived stress is negatively associated with activities of daily living and subjective quality of life in younger, middle, and older autistic adults / Goldie A. MCQUAID in Autism Research, 15-8 (August 2022)
[article]
Titre : Increased perceived stress is negatively associated with activities of daily living and subjective quality of life in younger, middle, and older autistic adults Type de document : Texte imprimé et/ou numérique Auteurs : Goldie A. MCQUAID, Auteur ; Colin H. WEISS, Auteur ; Alex Job SAID, Auteur ; Kevin A. PELPHREY, Auteur ; Nancy Raitano LEE, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : p.1535-1549 Langues : Anglais (eng) Mots-clés : Activities of Daily Living Adult Aged Autism Spectrum Disorder/psychology Autistic Disorder/psychology Female Humans Infant, Newborn Male Quality of Life/psychology Stress, Psychological/complications/epidemiology/psychology adulthood autism perceived stress subjective quality of life Index. décimale : PER Périodiques Résumé : Few studies have examined self-reported perceived stress in autistic adults. Existing studies have included relatively small, predominantly male samples and have not included older autistic adults. Using a large autistic sample (NÂ =Â 713), enriched for individuals designated female at birth (59.3%), and spanning younger, middle, and older adulthood, we examined perceived stress and its associations with independence in activities of daily living and subjective quality of life (QoL). Perceived stress for autistic adults designated male or female at birth was compared to their same birth-sex counterparts in a general population sample. In addition, within the autistic sample, effects of sex designated at birth, age, and their interaction were examined. Regression modeling examined associations between perceived stress and independence in activities of daily living and domains of subjective QoL in autistic adults, after controlling for age, sex designated at birth, and household income. Autistic adults reported significantly greater perceived stress than a general population comparison sample. Relative to autistic adults designated male at birth, those designated female at birth demonstrated significantly elevated perceived stress. Perceived stress contributed significantly to all regression models, with greater perceived stress associated with less independence in activities of daily living, and poorer subjective QoL across all domains-Physical, Psychological, Social, Environment, and Autism-related QoL. Findings are contextualized within the literature documenting that autistic individuals experience elevated underemployment and unemployment, heightened rates of adverse life events, and increased exposure to minority stress. LAY SUMMARY: This study looked at self-reported perceived stress in a large sample of autistic adults. Autistic adults reported more perceived stress than non-autistic adults. Autistic individuals designated female at birth reported higher stress than autistic individuals designated male at birth. In autistic adults, greater perceived stress is related to less independence in activities of daily living and poorer subjective quality of life. En ligne : http://dx.doi.org/10.1002/aur.2779 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483
in Autism Research > 15-8 (August 2022) . - p.1535-1549[article] Increased perceived stress is negatively associated with activities of daily living and subjective quality of life in younger, middle, and older autistic adults [Texte imprimé et/ou numérique] / Goldie A. MCQUAID, Auteur ; Colin H. WEISS, Auteur ; Alex Job SAID, Auteur ; Kevin A. PELPHREY, Auteur ; Nancy Raitano LEE, Auteur ; Gregory L. WALLACE, Auteur . - p.1535-1549.
Langues : Anglais (eng)
in Autism Research > 15-8 (August 2022) . - p.1535-1549
Mots-clés : Activities of Daily Living Adult Aged Autism Spectrum Disorder/psychology Autistic Disorder/psychology Female Humans Infant, Newborn Male Quality of Life/psychology Stress, Psychological/complications/epidemiology/psychology adulthood autism perceived stress subjective quality of life Index. décimale : PER Périodiques Résumé : Few studies have examined self-reported perceived stress in autistic adults. Existing studies have included relatively small, predominantly male samples and have not included older autistic adults. Using a large autistic sample (NÂ =Â 713), enriched for individuals designated female at birth (59.3%), and spanning younger, middle, and older adulthood, we examined perceived stress and its associations with independence in activities of daily living and subjective quality of life (QoL). Perceived stress for autistic adults designated male or female at birth was compared to their same birth-sex counterparts in a general population sample. In addition, within the autistic sample, effects of sex designated at birth, age, and their interaction were examined. Regression modeling examined associations between perceived stress and independence in activities of daily living and domains of subjective QoL in autistic adults, after controlling for age, sex designated at birth, and household income. Autistic adults reported significantly greater perceived stress than a general population comparison sample. Relative to autistic adults designated male at birth, those designated female at birth demonstrated significantly elevated perceived stress. Perceived stress contributed significantly to all regression models, with greater perceived stress associated with less independence in activities of daily living, and poorer subjective QoL across all domains-Physical, Psychological, Social, Environment, and Autism-related QoL. Findings are contextualized within the literature documenting that autistic individuals experience elevated underemployment and unemployment, heightened rates of adverse life events, and increased exposure to minority stress. LAY SUMMARY: This study looked at self-reported perceived stress in a large sample of autistic adults. Autistic adults reported more perceived stress than non-autistic adults. Autistic individuals designated female at birth reported higher stress than autistic individuals designated male at birth. In autistic adults, greater perceived stress is related to less independence in activities of daily living and poorer subjective quality of life. En ligne : http://dx.doi.org/10.1002/aur.2779 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483 Measuring flexibility in autistic adults: Exploring the factor structure of the flexibility scale self report / Goldie A. MCQUAID ; Benjamin E. YERYS ; John F. STRANG ; Laura G. ANTHONY ; Lauren KENWORTHY ; Nancy R. LEE ; Gregory L. WALLACE in Autism Research, 16-11 (November 2023)
[article]
Titre : Measuring flexibility in autistic adults: Exploring the factor structure of the flexibility scale self report Type de document : Texte imprimé et/ou numérique Auteurs : Goldie A. MCQUAID, Auteur ; Benjamin E. YERYS, Auteur ; John F. STRANG, Auteur ; Laura G. ANTHONY, Auteur ; Lauren KENWORTHY, Auteur ; Nancy R. LEE, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : p.2208-2219 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Cognitive flexibility differences are common for autistic individuals and have an impact on a range of clinical outcomes. However, there is currently a lack of well validated measurement tools to assess flexibility in adulthood. The Flexibility Scale was originally designed as a parent-report measure of real-world flexibility challenges in youth. The original Flexibility Scale provides a total score and five subscales: Routines and Rituals, Transitions and Change, Special Interests, Social Flexibility, and Generativity. In this study, we evaluate the factorial validity of the Flexibility Scale as a self-report (Flexibility Scale Self Report) measure of cognitive flexibility, adapted from the original Flexibility Scale, for use by autistic adults. This study includes both a primary sample (n=813; mean age=40.3; 59% female) and an independently recruited replication sample (n=120; mean age=32.8; 74% female) of individuals who completed the Flexibility Scale Self Report. The analysis consisted of an initial confirmatory factor analysis (CFA) of the original Flexibility Scale structure, followed by exploratory factor analysis (EFA) and factor optimization within a structural equation modeling framework to identify the optimal structure for the questionnaire in adults. The identified structure was then replicated through CFA in the replication sample. Our results indicate an alternative optimal scale structure from the original Flexibility Scale, which includes fewer items, and only three (Routines/Rituals, Transitions and Change, Special Interests) of the five subscales contributing to the flexibility total score. Comparisons revealed no structural differences within the scale based on sex assigned at birth. Here the Generativity and Social Flexibility scales are treated as independent but related scales. The implications for measurement of cognitive flexibility in clinical and research settings, as well as theoretical underpinnings are discussed. En ligne : https://doi.org/10.1002/aur.3025 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517
in Autism Research > 16-11 (November 2023) . - p.2208-2219[article] Measuring flexibility in autistic adults: Exploring the factor structure of the flexibility scale self report [Texte imprimé et/ou numérique] / Goldie A. MCQUAID, Auteur ; Benjamin E. YERYS, Auteur ; John F. STRANG, Auteur ; Laura G. ANTHONY, Auteur ; Lauren KENWORTHY, Auteur ; Nancy R. LEE, Auteur ; Gregory L. WALLACE, Auteur . - p.2208-2219.
Langues : Anglais (eng)
in Autism Research > 16-11 (November 2023) . - p.2208-2219
Index. décimale : PER Périodiques Résumé : Abstract Cognitive flexibility differences are common for autistic individuals and have an impact on a range of clinical outcomes. However, there is currently a lack of well validated measurement tools to assess flexibility in adulthood. The Flexibility Scale was originally designed as a parent-report measure of real-world flexibility challenges in youth. The original Flexibility Scale provides a total score and five subscales: Routines and Rituals, Transitions and Change, Special Interests, Social Flexibility, and Generativity. In this study, we evaluate the factorial validity of the Flexibility Scale as a self-report (Flexibility Scale Self Report) measure of cognitive flexibility, adapted from the original Flexibility Scale, for use by autistic adults. This study includes both a primary sample (n=813; mean age=40.3; 59% female) and an independently recruited replication sample (n=120; mean age=32.8; 74% female) of individuals who completed the Flexibility Scale Self Report. The analysis consisted of an initial confirmatory factor analysis (CFA) of the original Flexibility Scale structure, followed by exploratory factor analysis (EFA) and factor optimization within a structural equation modeling framework to identify the optimal structure for the questionnaire in adults. The identified structure was then replicated through CFA in the replication sample. Our results indicate an alternative optimal scale structure from the original Flexibility Scale, which includes fewer items, and only three (Routines/Rituals, Transitions and Change, Special Interests) of the five subscales contributing to the flexibility total score. Comparisons revealed no structural differences within the scale based on sex assigned at birth. Here the Generativity and Social Flexibility scales are treated as independent but related scales. The implications for measurement of cognitive flexibility in clinical and research settings, as well as theoretical underpinnings are discussed. En ligne : https://doi.org/10.1002/aur.3025 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 Predictors of sleep quality for autistic people across adulthood / Rebecca A. CHARLTON in Autism Research, 16-4 (April 2023)
PermalinkSelf-reported cognitive decline among middle and older age autistic adults / Claire B. KLEIN in Autism Research, 16-3 (March 2023)
PermalinkSelf-reported memory of autistic young adults and associated real-world outcomes / Goldie A. MCQUAID ; Gregory L. WALLACE ; Nancy Raitano LEE in Research in Autism Spectrum Disorders, 109 (November 2023)
PermalinkSocial support and links to quality of life among middle-aged and older autistic adults / Rebecca A. CHARLTON in Autism, 27-1 (January 2023)
PermalinkThe gap between IQ and adaptive functioning in autism spectrum disorder: Disentangling diagnostic and sex differences / Goldie A. MCQUAID in Autism, 26-6 (August 2022)
PermalinkVocational Outcomes in ASD: An Examination of Work Readiness Skills as well as Barriers and Facilitators to Employment Identified by Autistic Adults / Goldie A. MCQUAID ; Hannah E. GROSMAN ; Sanjana JAYARAM ; Gregory L. WALLACE in Journal of Autism and Developmental Disorders, 54-2 (February 2024)
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