Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
4 recherche sur le mot-clé 'Evoked Potentials/physiology'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
Attribution of intentions in autism spectrum disorder: A study of event-related potentials / João Miguel FERNANDES in Autism Research, 15-5 (May 2022)
[article]
Titre : Attribution of intentions in autism spectrum disorder: A study of event-related potentials Type de document : Texte imprimé et/ou numérique Auteurs : João Miguel FERNANDES, Auteur ; Sara SOARES, Auteur ; Ricardo LOPES, Auteur ; Rita JERÓNIMO, Auteur ; J. Bernardo BARAHONA-CORREA, Auteur Article en page(s) : p.847-860 Langues : Anglais (eng) Mots-clés : Adult Autism Spectrum Disorder Autistic Disorder Evoked Potentials/physiology Female Humans Intention Male Social Perception attribution of intentions autism spectrum disorders event related potentials social cognition & theory of mind Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is characterized by social cognition deficits, including difficulties inferring the intentions of others. Although deficits in attribution of intentions (AI) have been consistently replicated in ASD, their exact nature remains unexplored. Here we registered the electrophysiological correlates of a nonverbal social cognition task to investigate AI in autistic adults. Twenty-one male autistic adults and 30 male neurotypical volunteers performed a comic strips task depicting either intentional action (AI) or physical causality with or without human characters, while their electroencephalographic signal was recorded. Compared to neurotypical volunteers, autistic participants were significantly less accurate in correctly identifying congruence in the AI condition, but not in the physical causality conditions. In the AI condition a bilateral posterior positive event-related potential (ERP) occurred 200-400?ms post-stimulus (the ERP intention effect) in both groups. This waveform comprised a P200 and a P300 component, with the P200 component being larger for the AI condition in neurotypical volunteers but not in autistic individuals, who also showed a longer latency for this waveform. Group differences in amplitude of the ERP intention effect only became evident when we compared autistic participants to a subgroup of similarly performing neurotypical participants, suggesting that the atypical ERP waveform in ASD is an effect of group, rather than a marker of low-task performance. Together, these results suggest that the lower accuracy of the ASD group in the AI task may result from impaired early attentional processing and contextual integration of socially relevant cues. LAY SUMMARY: To understand why autistic people have difficulties in inferring others' intentions, we asked participants to judge the congruence of the endings of comic strips depicting either intentional actions (e.g., fetching a chair to reach for something) or situations solely following physical rules (e.g., an apple falling on someone's head), while their electrical brain activity was recorded. Autistic individuals had more difficulties in inferring intentions than neurotypical controls, which may reflect impaired attention and contextual integration of social cues. En ligne : http://dx.doi.org/10.1002/aur.2702 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473
in Autism Research > 15-5 (May 2022) . - p.847-860[article] Attribution of intentions in autism spectrum disorder: A study of event-related potentials [Texte imprimé et/ou numérique] / João Miguel FERNANDES, Auteur ; Sara SOARES, Auteur ; Ricardo LOPES, Auteur ; Rita JERÓNIMO, Auteur ; J. Bernardo BARAHONA-CORREA, Auteur . - p.847-860.
Langues : Anglais (eng)
in Autism Research > 15-5 (May 2022) . - p.847-860
Mots-clés : Adult Autism Spectrum Disorder Autistic Disorder Evoked Potentials/physiology Female Humans Intention Male Social Perception attribution of intentions autism spectrum disorders event related potentials social cognition & theory of mind Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is characterized by social cognition deficits, including difficulties inferring the intentions of others. Although deficits in attribution of intentions (AI) have been consistently replicated in ASD, their exact nature remains unexplored. Here we registered the electrophysiological correlates of a nonverbal social cognition task to investigate AI in autistic adults. Twenty-one male autistic adults and 30 male neurotypical volunteers performed a comic strips task depicting either intentional action (AI) or physical causality with or without human characters, while their electroencephalographic signal was recorded. Compared to neurotypical volunteers, autistic participants were significantly less accurate in correctly identifying congruence in the AI condition, but not in the physical causality conditions. In the AI condition a bilateral posterior positive event-related potential (ERP) occurred 200-400?ms post-stimulus (the ERP intention effect) in both groups. This waveform comprised a P200 and a P300 component, with the P200 component being larger for the AI condition in neurotypical volunteers but not in autistic individuals, who also showed a longer latency for this waveform. Group differences in amplitude of the ERP intention effect only became evident when we compared autistic participants to a subgroup of similarly performing neurotypical participants, suggesting that the atypical ERP waveform in ASD is an effect of group, rather than a marker of low-task performance. Together, these results suggest that the lower accuracy of the ASD group in the AI task may result from impaired early attentional processing and contextual integration of socially relevant cues. LAY SUMMARY: To understand why autistic people have difficulties in inferring others' intentions, we asked participants to judge the congruence of the endings of comic strips depicting either intentional actions (e.g., fetching a chair to reach for something) or situations solely following physical rules (e.g., an apple falling on someone's head), while their electrical brain activity was recorded. Autistic individuals had more difficulties in inferring intentions than neurotypical controls, which may reflect impaired attention and contextual integration of social cues. En ligne : http://dx.doi.org/10.1002/aur.2702 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473 Cognitive and Electrophysiological Correlates of Working Memory Impairments in Neurofibromatosis Type 1 / Gorana POBRIC in Journal of Autism and Developmental Disorders, 52-4 (April 2022)
[article]
Titre : Cognitive and Electrophysiological Correlates of Working Memory Impairments in Neurofibromatosis Type 1 Type de document : Texte imprimé et/ou numérique Auteurs : Gorana POBRIC, Auteur ; Jason R. TAYLOR, Auteur ; Hemavathy M. RAMALINGAM, Auteur ; Emily PYE, Auteur ; Louise ROBINSON, Auteur ; Grace VASSALLO, Auteur ; JeYoung JUNG, Auteur ; Misty BHANDARY, Auteur ; Karolina SZUMANSKA-RYT, Auteur ; Louise THEODOSIOU, Auteur ; D. Gareth EVANS, Auteur ; Judith EELLOO, Auteur ; Emma BURKITT-WRIGHT, Auteur ; Johan HULLEMAN, Auteur ; Jonathan GREEN, Auteur ; Shruti GARG, Auteur Article en page(s) : p.1478-1494 Langues : Anglais (eng) Mots-clés : Adolescent Autism Spectrum Disorder Cognition Evoked Potentials/physiology Humans Memory, Short-Term/physiology Neurofibromatosis 1/complications Eeg N-back task Neurofibromatosis 1 P300 Working memory Index. décimale : PER Périodiques Résumé : Neurofibromatosis 1 (NF1) is a single gene disorder associated with working Memory (WM) impairments. The aim of this study was to investigate P300 event-related potential (ERP) associated with WM in NF1. Sixteen adolescents with NF1 were compared with controls on measures of WM and EEG was recorded during a WM nback task. The NF1 group showed poorer performance on measures of WM as compared to the control group. No group differences were observed in P300 amplitude at Pz, but P300 latency was shorter in the NF1 group. Topographic analyses of P300 amplitude showed group differences indicating neural processing differences in the NF1 group relative to controls, which possibly contribute to the cognitive deficits seen in this population. En ligne : http://dx.doi.org/10.1007/s10803-021-05043-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475
in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1478-1494[article] Cognitive and Electrophysiological Correlates of Working Memory Impairments in Neurofibromatosis Type 1 [Texte imprimé et/ou numérique] / Gorana POBRIC, Auteur ; Jason R. TAYLOR, Auteur ; Hemavathy M. RAMALINGAM, Auteur ; Emily PYE, Auteur ; Louise ROBINSON, Auteur ; Grace VASSALLO, Auteur ; JeYoung JUNG, Auteur ; Misty BHANDARY, Auteur ; Karolina SZUMANSKA-RYT, Auteur ; Louise THEODOSIOU, Auteur ; D. Gareth EVANS, Auteur ; Judith EELLOO, Auteur ; Emma BURKITT-WRIGHT, Auteur ; Johan HULLEMAN, Auteur ; Jonathan GREEN, Auteur ; Shruti GARG, Auteur . - p.1478-1494.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1478-1494
Mots-clés : Adolescent Autism Spectrum Disorder Cognition Evoked Potentials/physiology Humans Memory, Short-Term/physiology Neurofibromatosis 1/complications Eeg N-back task Neurofibromatosis 1 P300 Working memory Index. décimale : PER Périodiques Résumé : Neurofibromatosis 1 (NF1) is a single gene disorder associated with working Memory (WM) impairments. The aim of this study was to investigate P300 event-related potential (ERP) associated with WM in NF1. Sixteen adolescents with NF1 were compared with controls on measures of WM and EEG was recorded during a WM nback task. The NF1 group showed poorer performance on measures of WM as compared to the control group. No group differences were observed in P300 amplitude at Pz, but P300 latency was shorter in the NF1 group. Topographic analyses of P300 amplitude showed group differences indicating neural processing differences in the NF1 group relative to controls, which possibly contribute to the cognitive deficits seen in this population. En ligne : http://dx.doi.org/10.1007/s10803-021-05043-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 Implicit Semantic Processing of Linguistic and Non-linguistic Stimuli in Adults with Autism Spectrum Disorder / E. O'ROURKE in Journal of Autism and Developmental Disorders, 51-8 (August 2021)
[article]
Titre : Implicit Semantic Processing of Linguistic and Non-linguistic Stimuli in Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : E. O'ROURKE, Auteur ; E. L. CODERRE, Auteur Article en page(s) : p.2611-2630 Langues : Anglais (eng) Mots-clés : Acoustic Stimulation/psychology Adolescent Adult Autism Spectrum Disorder/physiopathology/psychology Autistic Disorder Electroencephalography Evoked Potentials/physiology Humans Language Male Semantics Autism Event-related potentials N400 Semantic integration Index. décimale : PER Périodiques Résumé : While many individuals with autism spectrum disorder (ASD) experience difficulties with language processing, non-linguistic semantic processing may be intact. We examined neural responses to an implicit semantic priming task by comparing N400 responses-an event-related potential related to semantic processing-in response to semantically related or unrelated pairs of words or pictures. Adults with ASD showed larger N400 responses than typically developing adults for pictures, but no group differences occurred for words. However, we also observed complex modulations of N400 amplitude by age and by level of autistic traits. These results offer important implications for how groups are delineated and compared in autism research. En ligne : http://dx.doi.org/10.1007/s10803-020-04736-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452
in Journal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2611-2630[article] Implicit Semantic Processing of Linguistic and Non-linguistic Stimuli in Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / E. O'ROURKE, Auteur ; E. L. CODERRE, Auteur . - p.2611-2630.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2611-2630
Mots-clés : Acoustic Stimulation/psychology Adolescent Adult Autism Spectrum Disorder/physiopathology/psychology Autistic Disorder Electroencephalography Evoked Potentials/physiology Humans Language Male Semantics Autism Event-related potentials N400 Semantic integration Index. décimale : PER Périodiques Résumé : While many individuals with autism spectrum disorder (ASD) experience difficulties with language processing, non-linguistic semantic processing may be intact. We examined neural responses to an implicit semantic priming task by comparing N400 responses-an event-related potential related to semantic processing-in response to semantically related or unrelated pairs of words or pictures. Adults with ASD showed larger N400 responses than typically developing adults for pictures, but no group differences occurred for words. However, we also observed complex modulations of N400 amplitude by age and by level of autistic traits. These results offer important implications for how groups are delineated and compared in autism research. En ligne : http://dx.doi.org/10.1007/s10803-020-04736-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 Sex differences in automatic emotion regulation in adolescents with autism spectrum disorder / Alexandra P. KEY in Autism Research, 15-4 (April 2022)
[article]
Titre : Sex differences in automatic emotion regulation in adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Alexandra P. KEY, Auteur ; Dorita JONES, Auteur ; Blythe A. CORBETT, Auteur Article en page(s) : p.712-728 Langues : Anglais (eng) Mots-clés : Adolescent Autism Spectrum Disorder Child Emotional Regulation Emotions/physiology Evoked Potentials/physiology Facial Expression Female Humans Male Sex Characteristics autism emotion face inhibition sex target detection Index. décimale : PER Périodiques Résumé : Autism may be underdiagnosed in females because their social difficulties are often less noticeable. This study explored sex differences in automatic facial emotion processing in 45 adolescents with autism spectrum disorder (22 female, 23 male), age 10-16?years, performing active target detection task and Go/NoGo tasks where faces with positive and negative emotional expressions served as irrelevant distractors. The combined sample demonstrated more accurate performance on the target detection (response initiation) than the Go/NoGo task (response inhibition), replicating findings previously reported in typical participants. Females exhibited greater difficulty than males with response initiation in the target detection task, especially in the context of angry faces, while males found withholding a response in the Go/NoGo block with happy faces more challenging. Electrophysiological data revealed no sex differences or emotion discrimination effects during the early perceptual processing of faces indexed by the occipitotemporal N170. Autistic males demonstrated increased frontal N2 and parietal P3 amplitudes compared to females, suggesting greater neural resource allocation to automatic emotion regulation processes. The associations between standardized behavioral measures (autism severity, theory of mind skills) and brain responses also varied by sex: more adaptive social functioning was related to the speed of perceptual processing (N170 latency) in females and the extent of deliberate attention allocation (P3 amplitudes) in males. Together, these findings suggest that males and females with autism may rely on different strategies for social functioning and highlight the importance of considering sex differences in autism. LAY SUMMARY: Females with autism may exhibit less noticeable social difficulties than males. This study demonstrates that autistic females are more successful than males at inhibiting behavioral responses in emotional contexts, while males are more likely to initiate a response. At the neural level, social functioning in females is related to the speed of automatic perceptual processing of facial cues, and in males, to the extent of active attention allocation to the stimuli. These findings highlight the importance of considering sex differences in autism diagnosis and treatment selection. En ligne : https://dx.doi.org/10.1002/aur.2678 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473
in Autism Research > 15-4 (April 2022) . - p.712-728[article] Sex differences in automatic emotion regulation in adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / Alexandra P. KEY, Auteur ; Dorita JONES, Auteur ; Blythe A. CORBETT, Auteur . - p.712-728.
Langues : Anglais (eng)
in Autism Research > 15-4 (April 2022) . - p.712-728
Mots-clés : Adolescent Autism Spectrum Disorder Child Emotional Regulation Emotions/physiology Evoked Potentials/physiology Facial Expression Female Humans Male Sex Characteristics autism emotion face inhibition sex target detection Index. décimale : PER Périodiques Résumé : Autism may be underdiagnosed in females because their social difficulties are often less noticeable. This study explored sex differences in automatic facial emotion processing in 45 adolescents with autism spectrum disorder (22 female, 23 male), age 10-16?years, performing active target detection task and Go/NoGo tasks where faces with positive and negative emotional expressions served as irrelevant distractors. The combined sample demonstrated more accurate performance on the target detection (response initiation) than the Go/NoGo task (response inhibition), replicating findings previously reported in typical participants. Females exhibited greater difficulty than males with response initiation in the target detection task, especially in the context of angry faces, while males found withholding a response in the Go/NoGo block with happy faces more challenging. Electrophysiological data revealed no sex differences or emotion discrimination effects during the early perceptual processing of faces indexed by the occipitotemporal N170. Autistic males demonstrated increased frontal N2 and parietal P3 amplitudes compared to females, suggesting greater neural resource allocation to automatic emotion regulation processes. The associations between standardized behavioral measures (autism severity, theory of mind skills) and brain responses also varied by sex: more adaptive social functioning was related to the speed of perceptual processing (N170 latency) in females and the extent of deliberate attention allocation (P3 amplitudes) in males. Together, these findings suggest that males and females with autism may rely on different strategies for social functioning and highlight the importance of considering sex differences in autism. LAY SUMMARY: Females with autism may exhibit less noticeable social difficulties than males. This study demonstrates that autistic females are more successful than males at inhibiting behavioral responses in emotional contexts, while males are more likely to initiate a response. At the neural level, social functioning in females is related to the speed of automatic perceptual processing of facial cues, and in males, to the extent of active attention allocation to the stimuli. These findings highlight the importance of considering sex differences in autism diagnosis and treatment selection. En ligne : https://dx.doi.org/10.1002/aur.2678 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473