Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
1 recherche sur le mot-clé 'Fetal brain'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
Behavioral Correlates of Maternal Antibody Status Among Children with Autism / Daniel BRAUNSCHWEIG in Journal of Autism and Developmental Disorders, 42-7 (July 2012)
[article]
Titre : Behavioral Correlates of Maternal Antibody Status Among Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Daniel BRAUNSCHWEIG, Auteur ; Paul DUNCANSON, Auteur ; Robert BOYCE, Auteur ; David J. HANSEN, Auteur ; Paul ASHWOOD, Auteur ; Isaac N. PESSAH, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Judy VAN DE WATER, Auteur Année de publication : 2012 Article en page(s) : p.1435-1445 Langues : Anglais (eng) Mots-clés : Autism Maternal antibodies Autoantibodies Fetal brain Immunologie Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) affect approximately 1 in 110 children in the United States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of children with autism and controls, yielding significant associations between the presence of IgG reactivity to fetal brain proteins at 37 and 73 kDa and a childhood diagnosis of full autism (p = 0.0005), which also correlated with lower expressive language scores (p = 0.005). Additionally, we report on reactivity to proteins at 39 and 73 kDa, which correlated with the broader diagnosis of ASD (p = 0.0007) and increased irritability on the Aberrant Behavioral Checklist (p = 0.05). This study provides evidence of multiple patterns of reactivity to fetal brain proteins by maternal antibodies associated with ASD and specific childhood behavioral outcomes. En ligne : http://dx.doi.org/10.1007/s10803-011-1378-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166
in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1435-1445[article] Behavioral Correlates of Maternal Antibody Status Among Children with Autism [Texte imprimé et/ou numérique] / Daniel BRAUNSCHWEIG, Auteur ; Paul DUNCANSON, Auteur ; Robert BOYCE, Auteur ; David J. HANSEN, Auteur ; Paul ASHWOOD, Auteur ; Isaac N. PESSAH, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Judy VAN DE WATER, Auteur . - 2012 . - p.1435-1445.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1435-1445
Mots-clés : Autism Maternal antibodies Autoantibodies Fetal brain Immunologie Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) affect approximately 1 in 110 children in the United States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of children with autism and controls, yielding significant associations between the presence of IgG reactivity to fetal brain proteins at 37 and 73 kDa and a childhood diagnosis of full autism (p = 0.0005), which also correlated with lower expressive language scores (p = 0.005). Additionally, we report on reactivity to proteins at 39 and 73 kDa, which correlated with the broader diagnosis of ASD (p = 0.0007) and increased irritability on the Aberrant Behavioral Checklist (p = 0.05). This study provides evidence of multiple patterns of reactivity to fetal brain proteins by maternal antibodies associated with ASD and specific childhood behavioral outcomes. En ligne : http://dx.doi.org/10.1007/s10803-011-1378-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166