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Higher Tactile Temporal Resolution as a Basis of Hypersensitivity in Individuals with Autism Spectrum Disorder / M. IDE in Journal of Autism and Developmental Disorders, 49-1 (January 2019)
[article]
Titre : Higher Tactile Temporal Resolution as a Basis of Hypersensitivity in Individuals with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : M. IDE, Auteur ; A. YAGUCHI, Auteur ; M. SANO, Auteur ; R. FUKATSU, Auteur ; M. WADA, Auteur Article en page(s) : p.44-53 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Detection threshold/sensitivity E/I imbalance Hypersensitivity Tactile Temporal order judgment Index. décimale : PER Périodiques Résumé : Many individuals with autism spectrum disorder (ASD) have symptoms of sensory hypersensitivity. Several studies have shown high individual variations in temporal processing of tactile stimuli. We hypothesized that these individual differences are linked to differences in hyper-reactivity among individuals with ASD. Participants performed two tasks as to vibrotactile stimuli: One is a temporal order judgement task, and another is a detection task. We found that individuals with ASD with higher temporal resolution tended to have more severe hypersensitivity symptoms. In contrast, the tactile detection threshold/sensitivity were related to the severities of stereotyped behaviour and restricted interests, rather than to hypersensitivity. Our findings demonstrate that higher temporal resolution to sensory stimuli may contribute to sensory hypersensitivity in individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3677-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376
in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.44-53[article] Higher Tactile Temporal Resolution as a Basis of Hypersensitivity in Individuals with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / M. IDE, Auteur ; A. YAGUCHI, Auteur ; M. SANO, Auteur ; R. FUKATSU, Auteur ; M. WADA, Auteur . - p.44-53.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.44-53
Mots-clés : Autism spectrum disorder Detection threshold/sensitivity E/I imbalance Hypersensitivity Tactile Temporal order judgment Index. décimale : PER Périodiques Résumé : Many individuals with autism spectrum disorder (ASD) have symptoms of sensory hypersensitivity. Several studies have shown high individual variations in temporal processing of tactile stimuli. We hypothesized that these individual differences are linked to differences in hyper-reactivity among individuals with ASD. Participants performed two tasks as to vibrotactile stimuli: One is a temporal order judgement task, and another is a detection task. We found that individuals with ASD with higher temporal resolution tended to have more severe hypersensitivity symptoms. In contrast, the tactile detection threshold/sensitivity were related to the severities of stereotyped behaviour and restricted interests, rather than to hypersensitivity. Our findings demonstrate that higher temporal resolution to sensory stimuli may contribute to sensory hypersensitivity in individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3677-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376 Linking Anxiety and Insistence on Sameness in Autistic Children: The Role of Sensory Hypersensitivity / Karen R. BLACK in Journal of Autism and Developmental Disorders, 47-8 (August 2017)
[article]
Titre : Linking Anxiety and Insistence on Sameness in Autistic Children: The Role of Sensory Hypersensitivity Type de document : Texte imprimé et/ou numérique Auteurs : Karen R. BLACK, Auteur ; Ryan A. STEVENSON, Auteur ; Magali SEGERS, Auteur ; Busiswe L. NCUBE, Auteur ; Sol Z. SUN, Auteur ; Aviva PHILIPP-MULLER, Auteur ; James M. BEBKO, Auteur ; Morgan D. BARENSE, Auteur ; Susanne FERBER, Auteur Article en page(s) : p.2459-2470 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Hypersensitivity Anxiety Insistence on sameness Sensory processing Index. décimale : PER Périodiques Résumé : Sensory hypersensitivity and insistence on sameness (I/S) are common, co-occurring features of autism, yet the relationship between them is poorly understood. This study assessed the impact of sensory hypersensitivity on the clinical symptoms of specific phobia, separation anxiety, social anxiety and I/S for autistic and typically developing (TD) children. Parents of 79 children completed questionnaires on their child’s difficulties related to sensory processing, I/S, and anxiety. Results demonstrated that sensory hypersensitivity mediated 67% of the relationship between symptoms of specific phobia and I/S and 57% of the relationship between separation anxiety and I/S. No relationship was observed between sensory hypersensitivity and social anxiety. These mediation effects of sensory hypersensitivity were found only in autistic children, not in TD children. En ligne : https://doi.org/10.1007/s10803-017-3161-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=314
in Journal of Autism and Developmental Disorders > 47-8 (August 2017) . - p.2459-2470[article] Linking Anxiety and Insistence on Sameness in Autistic Children: The Role of Sensory Hypersensitivity [Texte imprimé et/ou numérique] / Karen R. BLACK, Auteur ; Ryan A. STEVENSON, Auteur ; Magali SEGERS, Auteur ; Busiswe L. NCUBE, Auteur ; Sol Z. SUN, Auteur ; Aviva PHILIPP-MULLER, Auteur ; James M. BEBKO, Auteur ; Morgan D. BARENSE, Auteur ; Susanne FERBER, Auteur . - p.2459-2470.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-8 (August 2017) . - p.2459-2470
Mots-clés : Autism spectrum disorder Hypersensitivity Anxiety Insistence on sameness Sensory processing Index. décimale : PER Périodiques Résumé : Sensory hypersensitivity and insistence on sameness (I/S) are common, co-occurring features of autism, yet the relationship between them is poorly understood. This study assessed the impact of sensory hypersensitivity on the clinical symptoms of specific phobia, separation anxiety, social anxiety and I/S for autistic and typically developing (TD) children. Parents of 79 children completed questionnaires on their child’s difficulties related to sensory processing, I/S, and anxiety. Results demonstrated that sensory hypersensitivity mediated 67% of the relationship between symptoms of specific phobia and I/S and 57% of the relationship between separation anxiety and I/S. No relationship was observed between sensory hypersensitivity and social anxiety. These mediation effects of sensory hypersensitivity were found only in autistic children, not in TD children. En ligne : https://doi.org/10.1007/s10803-017-3161-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=314 Revised scored Sensory Perception Quotient reveals sensory hypersensitivity in women with autism / Emily TAYLOR in Molecular Autism, 11 (2020)
[article]
Titre : Revised scored Sensory Perception Quotient reveals sensory hypersensitivity in women with autism Type de document : Texte imprimé et/ou numérique Auteurs : Emily TAYLOR, Auteur ; Rosemary HOLT, Auteur ; Teresa TAVASSOLI, Auteur ; Chris ASHWIN, Auteur ; Simon BARON-COHEN, Auteur Article en page(s) : 18 p. Langues : Anglais (eng) Mots-clés : Autism spectrum conditions Broader autism phenotype Hypersensitivity Sensory Sensory Perception Quotient females Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous research using the Sensory Perception Quotient (SPQ) has reported greater sensory hypersensitivity in people with autism spectrum condition (ASC) compared to controls, consistent with other research. However, current scoring of the SPQ does not differentiate between hyper and hyposensitivity, making it uncertain whether individuals with ASC might also show differences in hyposensitivity. Furthermore, no research to date has focused on sensory differences in females, and whether differences in sensory sensitivity extend to the broader autism phenotype (BAP). The present study aimed to fill these gaps. METHODS: The present study developed and validated a Revised Scoring of the Sensory Perception Quotient (SPQ-RS) in order to investigate self-reported hypersensitivity and hyposensitivity in three groups of adults: a female ASC group (n = 152), mothers of children with ASC (BAP mothers group; n = 103), and a control mothers group (n = 74). All participants completed the SPQ as a self-report measure of sensory processing and the Autism-Spectrum Quotient (AQ) as a measure of the degree of autism traits. RESULTS: The female ASC group reported significantly more hypersensitivity, but not more hyposensitivity, compared to the control female and BAP mothers groups. The BAP mothers group did not differ from the control mothers group in either reported hypersensitivity (p = .365) or hyposensitivity (p = .075), suggesting atypical sensory sensitivity is not a BAP trait within females. SPQ-RS hypersensitivity scores positively correlated with autistic traits in the female ASC (r = .266) and BAP mothers groups (r = .350). CONCLUSIONS: The present findings revealed greater sensory hypersensitivity, but not hyposensitivity, in females with ASC compared to BAP and control female groups, and that a greater degree of autism traits relates to higher hypersensitivity in ASC females. The results offer support for the enhanced perceptual functioning model using large samples of females, who are an understudied population, and demonstrate the validity of the SPQ-RS as a valuable new research tool for exploring self-reported hypersensitivity and hyposensitivity. En ligne : http://dx.doi.org/10.1186/s13229-019-0289-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427
in Molecular Autism > 11 (2020) . - 18 p.[article] Revised scored Sensory Perception Quotient reveals sensory hypersensitivity in women with autism [Texte imprimé et/ou numérique] / Emily TAYLOR, Auteur ; Rosemary HOLT, Auteur ; Teresa TAVASSOLI, Auteur ; Chris ASHWIN, Auteur ; Simon BARON-COHEN, Auteur . - 18 p.
Langues : Anglais (eng)
in Molecular Autism > 11 (2020) . - 18 p.
Mots-clés : Autism spectrum conditions Broader autism phenotype Hypersensitivity Sensory Sensory Perception Quotient females Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous research using the Sensory Perception Quotient (SPQ) has reported greater sensory hypersensitivity in people with autism spectrum condition (ASC) compared to controls, consistent with other research. However, current scoring of the SPQ does not differentiate between hyper and hyposensitivity, making it uncertain whether individuals with ASC might also show differences in hyposensitivity. Furthermore, no research to date has focused on sensory differences in females, and whether differences in sensory sensitivity extend to the broader autism phenotype (BAP). The present study aimed to fill these gaps. METHODS: The present study developed and validated a Revised Scoring of the Sensory Perception Quotient (SPQ-RS) in order to investigate self-reported hypersensitivity and hyposensitivity in three groups of adults: a female ASC group (n = 152), mothers of children with ASC (BAP mothers group; n = 103), and a control mothers group (n = 74). All participants completed the SPQ as a self-report measure of sensory processing and the Autism-Spectrum Quotient (AQ) as a measure of the degree of autism traits. RESULTS: The female ASC group reported significantly more hypersensitivity, but not more hyposensitivity, compared to the control female and BAP mothers groups. The BAP mothers group did not differ from the control mothers group in either reported hypersensitivity (p = .365) or hyposensitivity (p = .075), suggesting atypical sensory sensitivity is not a BAP trait within females. SPQ-RS hypersensitivity scores positively correlated with autistic traits in the female ASC (r = .266) and BAP mothers groups (r = .350). CONCLUSIONS: The present findings revealed greater sensory hypersensitivity, but not hyposensitivity, in females with ASC compared to BAP and control female groups, and that a greater degree of autism traits relates to higher hypersensitivity in ASC females. The results offer support for the enhanced perceptual functioning model using large samples of females, who are an understudied population, and demonstrate the validity of the SPQ-RS as a valuable new research tool for exploring self-reported hypersensitivity and hyposensitivity. En ligne : http://dx.doi.org/10.1186/s13229-019-0289-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427 Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism / L. A. SAPEY-TRIOMPHE in Autism Research, 12-4 (April 2019)
[article]
Titre : Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism Type de document : Texte imprimé et/ou numérique Auteurs : L. A. SAPEY-TRIOMPHE, Auteur ; F. LAMBERTON, Auteur ; Sandrine SONIE, Auteur ; J. MATTOUT, Auteur ; C. SCHMITZ, Auteur Article en page(s) : p.562-575 Langues : Anglais (eng) Mots-clés : autism spectrum disorder gamma-aminobutyric acid hypersensitivity magnetic resonance spectroscopy somatosensory cortex touch Index. décimale : PER Périodiques Résumé : Sensory hypersensitivity is frequently encountered in autism spectrum disorder (ASD). Gamma-aminobutyric acid (GABA) has been hypothesized to play a role in tactile hypersensitivity. The aim of the present study was twofold. First, as a study showed that children with ASD have decreased GABA concentrations in the sensorimotor cortex, we aimed at determining whether the GABA reduction remained in adults with ASD. For this purpose, we used magnetic resonance spectroscopy to measure GABA concentration in the sensorimotor cortex of neurotypical adults (n = 19) and ASD adults (n = 18). Second, we aimed at characterizing correlations between GABA concentration and tactile hypersensitivity in ASD. GABA concentration in the sensorimotor cortex of adults with ASD was lower than in neurotypical adults (decrease by 17%). Interestingly, GABA concentrations were positively correlated with self-reported tactile hypersensitivity in adults with ASD (r = 0.50, P = 0.01), but not in neurotypical adults. In addition, GABA concentrations were negatively correlated with the intra-individual variation during threshold measurement, both in neurotypical adults (r = -0.47, P = 0.04) and in adults with ASD (r = -0.59, P = 0.01). In other words, in both groups, the higher the GABA level, the more precise the tactile sensation. These results highlight the key role of GABA in tactile sensitivity, and suggest that atypical GABA modulation contributes to tactile hypersensitivity in ASD. We discuss the hypothesis that hypersensitivity in ASD could be due to suboptimal predictions about sensations. Autism Research 2019, 12: 562-575. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: People with autism spectrum disorder (ASD) often experience tactile hypersensitivity. Here, our goal was to highlight a link between tactile hypersensitivity and the concentration of gamma-aminobutyric acid (GABA) (an inhibitory neurotransmitter) in the brain of adults with ASD. Indeed, self-reported hypersensitivity correlated with reduced GABA levels in brain areas processing touch. Our study suggests that this neurotransmitter may play a key role in tactile hypersensitivity in autism. En ligne : https://dx.doi.org/10.1002/aur.2073 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388
in Autism Research > 12-4 (April 2019) . - p.562-575[article] Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism [Texte imprimé et/ou numérique] / L. A. SAPEY-TRIOMPHE, Auteur ; F. LAMBERTON, Auteur ; Sandrine SONIE, Auteur ; J. MATTOUT, Auteur ; C. SCHMITZ, Auteur . - p.562-575.
Langues : Anglais (eng)
in Autism Research > 12-4 (April 2019) . - p.562-575
Mots-clés : autism spectrum disorder gamma-aminobutyric acid hypersensitivity magnetic resonance spectroscopy somatosensory cortex touch Index. décimale : PER Périodiques Résumé : Sensory hypersensitivity is frequently encountered in autism spectrum disorder (ASD). Gamma-aminobutyric acid (GABA) has been hypothesized to play a role in tactile hypersensitivity. The aim of the present study was twofold. First, as a study showed that children with ASD have decreased GABA concentrations in the sensorimotor cortex, we aimed at determining whether the GABA reduction remained in adults with ASD. For this purpose, we used magnetic resonance spectroscopy to measure GABA concentration in the sensorimotor cortex of neurotypical adults (n = 19) and ASD adults (n = 18). Second, we aimed at characterizing correlations between GABA concentration and tactile hypersensitivity in ASD. GABA concentration in the sensorimotor cortex of adults with ASD was lower than in neurotypical adults (decrease by 17%). Interestingly, GABA concentrations were positively correlated with self-reported tactile hypersensitivity in adults with ASD (r = 0.50, P = 0.01), but not in neurotypical adults. In addition, GABA concentrations were negatively correlated with the intra-individual variation during threshold measurement, both in neurotypical adults (r = -0.47, P = 0.04) and in adults with ASD (r = -0.59, P = 0.01). In other words, in both groups, the higher the GABA level, the more precise the tactile sensation. These results highlight the key role of GABA in tactile sensitivity, and suggest that atypical GABA modulation contributes to tactile hypersensitivity in ASD. We discuss the hypothesis that hypersensitivity in ASD could be due to suboptimal predictions about sensations. Autism Research 2019, 12: 562-575. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: People with autism spectrum disorder (ASD) often experience tactile hypersensitivity. Here, our goal was to highlight a link between tactile hypersensitivity and the concentration of gamma-aminobutyric acid (GABA) (an inhibitory neurotransmitter) in the brain of adults with ASD. Indeed, self-reported hypersensitivity correlated with reduced GABA levels in brain areas processing touch. Our study suggests that this neurotransmitter may play a key role in tactile hypersensitivity in autism. En ligne : https://dx.doi.org/10.1002/aur.2073 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 The Glasgow Sensory Questionnaire: Validation of a French Language Version and Refinement of Sensory Profiles of People with High Autism-Spectrum Quotient / L. A. SAPEY-TRIOMPHE in Journal of Autism and Developmental Disorders, 48-5 (May 2018)
[article]
Titre : The Glasgow Sensory Questionnaire: Validation of a French Language Version and Refinement of Sensory Profiles of People with High Autism-Spectrum Quotient Type de document : Texte imprimé et/ou numérique Auteurs : L. A. SAPEY-TRIOMPHE, Auteur ; A. MOULIN, Auteur ; Sandrine SONIE, Auteur ; C. SCHMITZ, Auteur Article en page(s) : p.1549-1565 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder Autism-Spectrum Quotient Cross-cultural adaptation Glasgow Sensory Questionnaire Hypersensitivity Index. décimale : PER Périodiques Résumé : Sensory sensitivity peculiarities represent an important characteristic of Autism Spectrum Disorders (ASD). We first validated a French language version of the Glasgow Sensory Questionnaire (GSQ) (Robertson and Simmons in J Autism Dev Disord 43(4):775-784, 2013). The GSQ score was strongly positively correlated with the Autism-Spectrum Quotient (AQ) (r = 0.81, p < 10(-6), n = 245). We further examined sensory profiles of groups with high versus low AQ. The high AQ group scored higher at the GSQ than the low AQ group for every sensory modality. Moreover, the high AQ group showed greater consistency in their patterns of hypersensitivity and hyposensitivity between sensory modalities, and stronger correlations between hyper and hyposensitivity. Results are discussed in the context of theories accounting for atypical sensory perception in ASD. En ligne : http://dx.doi.org/10.1007/s10803-017-3422-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355
in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1549-1565[article] The Glasgow Sensory Questionnaire: Validation of a French Language Version and Refinement of Sensory Profiles of People with High Autism-Spectrum Quotient [Texte imprimé et/ou numérique] / L. A. SAPEY-TRIOMPHE, Auteur ; A. MOULIN, Auteur ; Sandrine SONIE, Auteur ; C. SCHMITZ, Auteur . - p.1549-1565.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1549-1565
Mots-clés : Autism Spectrum Disorder Autism-Spectrum Quotient Cross-cultural adaptation Glasgow Sensory Questionnaire Hypersensitivity Index. décimale : PER Périodiques Résumé : Sensory sensitivity peculiarities represent an important characteristic of Autism Spectrum Disorders (ASD). We first validated a French language version of the Glasgow Sensory Questionnaire (GSQ) (Robertson and Simmons in J Autism Dev Disord 43(4):775-784, 2013). The GSQ score was strongly positively correlated with the Autism-Spectrum Quotient (AQ) (r = 0.81, p < 10(-6), n = 245). We further examined sensory profiles of groups with high versus low AQ. The high AQ group scored higher at the GSQ than the low AQ group for every sensory modality. Moreover, the high AQ group showed greater consistency in their patterns of hypersensitivity and hyposensitivity between sensory modalities, and stronger correlations between hyper and hyposensitivity. Results are discussed in the context of theories accounting for atypical sensory perception in ASD. En ligne : http://dx.doi.org/10.1007/s10803-017-3422-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355 Increased Sensory Processing Atypicalities in Parents of Multiplex ASD Families Versus Typically Developing and Simplex ASD Families / Chelsea K. DONALDSON in Journal of Autism and Developmental Disorders, 47-3 (March 2017)
PermalinkQuantitative Sensory Testing in adults with Autism Spectrum Disorders / Odette FRÜNDT in Journal of Autism and Developmental Disorders, 47-4 (April 2017)
PermalinkRelationship between physiological and parent-observed auditory over-responsiveness in children with typical development and those with autism spectrum disorders / H. TAKAHASHI in Autism, 22-3 (April 2018)
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