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Faire une suggestionIncidence of Physical Health Conditions in Autistic Children Within 5 Years After Their Autism Diagnosis / Yu-Chieh CHUANG in Autism Research, 18-10 (October 2025)
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[article]
Titre : Incidence of Physical Health Conditions in Autistic Children Within 5 Years After Their Autism Diagnosis Type de document : texte imprimé Auteurs : Yu-Chieh CHUANG, Auteur ; Yu-Jui HUANG, Auteur ; Meng-Chuan LAI, Auteur ; Sheng-Siang SU, Auteur ; Chian-Jue KUO, Auteur Article en page(s) : p.2088-2103 Langues : Anglais (eng) Mots-clés : autism comorbidity incidence incidence rate ratio physical illness prevalence Index. décimale : PER Périodiques Résumé : ABSTRACT This study aimed to investigate the incidence of physical illnesses of autistic young children compared with children in the general population. This population-based study included children (aged ≤?5?years) with newly diagnosed autism (autism group), followed up for 5?years after their autism diagnoses. Data were collected from Taiwan's National Health Insurance Research Database in the period of 2000?2019. Autistic children (n?=?45,680) were matched (1:20; by age and sex [assigned at birth]) with a comparison group from the general population (n?=?913,600). We calculated incidence rate ratios (IRRs) for physical illnesses diagnosed within 5?years after autism diagnoses. Data were analyzed using Poisson regression models adjusted for person-time and stratified by sex and the presence/absence of intellectual disabilities. The prevalence of almost all illnesses across major organ systems after 1?year of autism diagnosis was higher in the autism group than in the comparison group. The autism group exhibited significantly elevated incidence of cardiovascular disorders, cerebrovascular disorders, and endocrine diseases within 1?year after autism diagnosis (IRR 2.30?71.42). Although the incidence rates of these illnesses decreased over the 5-year follow-up period in the autism group, they remained higher than those in the comparison group, with most IRRs exceeding 2 in the fifth year after autism diagnosis. The IRRs were significant in both autistic male and female children and those with and without intellectual disabilities, although those with intellectual disabilities displayed descriptively larger IRRs. Autistic young children have heightened risks of being diagnosed with physical illnesses soon after their autism diagnoses. Future research should understand the etiological associations between autism and physical illnesses to offer tailored care from early in life. En ligne : https://doi.org/10.1002/aur.70109 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=569
in Autism Research > 18-10 (October 2025) . - p.2088-2103[article] Incidence of Physical Health Conditions in Autistic Children Within 5 Years After Their Autism Diagnosis [texte imprimé] / Yu-Chieh CHUANG, Auteur ; Yu-Jui HUANG, Auteur ; Meng-Chuan LAI, Auteur ; Sheng-Siang SU, Auteur ; Chian-Jue KUO, Auteur . - p.2088-2103.
Langues : Anglais (eng)
in Autism Research > 18-10 (October 2025) . - p.2088-2103
Mots-clés : autism comorbidity incidence incidence rate ratio physical illness prevalence Index. décimale : PER Périodiques Résumé : ABSTRACT This study aimed to investigate the incidence of physical illnesses of autistic young children compared with children in the general population. This population-based study included children (aged ≤?5?years) with newly diagnosed autism (autism group), followed up for 5?years after their autism diagnoses. Data were collected from Taiwan's National Health Insurance Research Database in the period of 2000?2019. Autistic children (n?=?45,680) were matched (1:20; by age and sex [assigned at birth]) with a comparison group from the general population (n?=?913,600). We calculated incidence rate ratios (IRRs) for physical illnesses diagnosed within 5?years after autism diagnoses. Data were analyzed using Poisson regression models adjusted for person-time and stratified by sex and the presence/absence of intellectual disabilities. The prevalence of almost all illnesses across major organ systems after 1?year of autism diagnosis was higher in the autism group than in the comparison group. The autism group exhibited significantly elevated incidence of cardiovascular disorders, cerebrovascular disorders, and endocrine diseases within 1?year after autism diagnosis (IRR 2.30?71.42). Although the incidence rates of these illnesses decreased over the 5-year follow-up period in the autism group, they remained higher than those in the comparison group, with most IRRs exceeding 2 in the fifth year after autism diagnosis. The IRRs were significant in both autistic male and female children and those with and without intellectual disabilities, although those with intellectual disabilities displayed descriptively larger IRRs. Autistic young children have heightened risks of being diagnosed with physical illnesses soon after their autism diagnoses. Future research should understand the etiological associations between autism and physical illnesses to offer tailored care from early in life. En ligne : https://doi.org/10.1002/aur.70109 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=569 Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study / Avital SEGEV in Autism Research, 12-12 (December)
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Titre : Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study Type de document : texte imprimé Auteurs : Avital SEGEV, Auteur ; Marc G. WEISSKOPF, Auteur ; Hagai LEVINE, Auteur ; Ofir PINTO, Auteur ; Raanan RAZ, Auteur Année de publication : 2019 Article en page(s) : p.1870-1879 Langues : Anglais (eng) Mots-clés : Israel autism spectrum disorder incidence socioeconomic factors Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) trends have been gaining a great deal of focus in recent decades, as many studies worldwide show a continued rise in incidence rates. Many researchers have begun analyzing socioeconomic data in relation to ASD in an effort to understand the source of these changing rates and the role of awareness and access to resources. In this study, we aim to contribute to this body of knowledge by examining incidence time trends of ASD in Israel according to socioeconomic factors. While similar studies have been conducted in Israel, this study is the first of its kind to include the total population. Individual-level data from the Israeli National Insurance Institute were used to determine cumulative incidence of ASD, first for the total population, and then stratified by population group and income categories. Multivariable logistic regression models were fit to analyze associations between income category and both risk of ASD and risk of ASD diagnosis in later age. A total of 431,348 children were examined in this study, with 13,841 cases of ASD. The cumulative incidence of all children aged 8 in 2015 was 0.64%, marking an increase compared to previous literature from Israel. Within our study period, ASD incidence followed this increase until the 2009 birth cohort, where it began to stabilize. Our initial findings from regression models showed strong positive associations between household income and ASD incidence, as expected. After factoring in population group, however, the elevated ASD incidence rates in the highest income bracket decreased. Autism Res 2019, 12: 1870-1879. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study contributes comprehensive and current data on ASD trends overtime in Israel and introduces crucial insights regarding the impact of socioeconomic factors on ASD diagnoses. We found a rise in ASD that began leveling off in 2009. We identified more ASD diagnoses occurring in families with higher incomes and in the General Population, pointing to the important role of sociodemographic factors on ASD diagnoses. En ligne : http://dx.doi.org/10.1002/aur.2185 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1870-1879[article] Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study [texte imprimé] / Avital SEGEV, Auteur ; Marc G. WEISSKOPF, Auteur ; Hagai LEVINE, Auteur ; Ofir PINTO, Auteur ; Raanan RAZ, Auteur . - 2019 . - p.1870-1879.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1870-1879
Mots-clés : Israel autism spectrum disorder incidence socioeconomic factors Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) trends have been gaining a great deal of focus in recent decades, as many studies worldwide show a continued rise in incidence rates. Many researchers have begun analyzing socioeconomic data in relation to ASD in an effort to understand the source of these changing rates and the role of awareness and access to resources. In this study, we aim to contribute to this body of knowledge by examining incidence time trends of ASD in Israel according to socioeconomic factors. While similar studies have been conducted in Israel, this study is the first of its kind to include the total population. Individual-level data from the Israeli National Insurance Institute were used to determine cumulative incidence of ASD, first for the total population, and then stratified by population group and income categories. Multivariable logistic regression models were fit to analyze associations between income category and both risk of ASD and risk of ASD diagnosis in later age. A total of 431,348 children were examined in this study, with 13,841 cases of ASD. The cumulative incidence of all children aged 8 in 2015 was 0.64%, marking an increase compared to previous literature from Israel. Within our study period, ASD incidence followed this increase until the 2009 birth cohort, where it began to stabilize. Our initial findings from regression models showed strong positive associations between household income and ASD incidence, as expected. After factoring in population group, however, the elevated ASD incidence rates in the highest income bracket decreased. Autism Res 2019, 12: 1870-1879. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study contributes comprehensive and current data on ASD trends overtime in Israel and introduces crucial insights regarding the impact of socioeconomic factors on ASD diagnoses. We found a rise in ASD that began leveling off in 2009. We identified more ASD diagnoses occurring in families with higher incomes and in the General Population, pointing to the important role of sociodemographic factors on ASD diagnoses. En ligne : http://dx.doi.org/10.1002/aur.2185 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Age-Specific Time Trends in Incidence Rates of Autism Spectrum Disorder Following Adaptation of DSM-5 and Other ASD-Related Regulatory Changes in Israel / Michael DAVIDOVITCH in Autism Research, 13-11 (November 2020)
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Titre : Age-Specific Time Trends in Incidence Rates of Autism Spectrum Disorder Following Adaptation of DSM-5 and Other ASD-Related Regulatory Changes in Israel Type de document : texte imprimé Auteurs : Michael DAVIDOVITCH, Auteur ; Ortal SLOBODIN, Auteur ; Marc G. WEISSKOPF, Auteur ; Ran S. ROTEM, Auteur Article en page(s) : p.1893-1901 Langues : Anglais (eng) Mots-clés : Dsm age trends autism spectrum disorder incidence late diagnosis Index. décimale : PER Périodiques Résumé : We analyzed data on 879,029 children born in 1999-2017 from a large Israeli health fund to evaluate time-trends in incidence of autism spectrum disorder (ASD). This included examining possible effects associated with the adaptation of the DSM-5 criteria for ASD, and the implementation of regulatory changes affecting eligibility for ASD-related stipends and services. ASD cases were ascertained based on electronic medical records review, with complete verification of ASD case status. Results indicated a substantial increase in ASD incidence rate (IR) over time that was overall not appreciably affected by the above changes. Cumulative incidence through age 8 rose from 0.46% (boys: 0.73; girls: 0.18) in 2007 to 1.30% (boys: 2.12; girls: 0.45) in 2018. Age-specific analyzes indicated that the largest increase in IR occurred in toddlers and preschool children, with a more modest increase at older age groups. Results suggest that the rise in early diagnosed ASD does not stem from a downward shift in the distribution of ages at first diagnosis, but rather from early detection of cases not previously diagnosed. Findings highlight the need to expand research aimed at identifying exogenous factors that may underlie the rise in incidence, and to evaluate factors that may contribute to late diagnosis of some cases. Autism Res 2020, 13: 1893-1901. © 2020 International Society for Autism Research and Wiley Periodicals LLC LAY SUMMARY: In an analysis of nearly 900,000 Israeli children born in 1999-2017, we found that the incidence of autism spectrum disorder (ASD) increased significantly over time, especially among toddlers and preschool children but also at older age groups. We additionally observed that changes affecting diagnostic criteria for ASD and eligibility for ASD-related services did not appreciably affect these trends. Results highlight the need to continue research aimed at identifying factors causing this increase and reasons contributing to late diagnosis of some cases. En ligne : http://dx.doi.org/10.1002/aur.2420 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433
in Autism Research > 13-11 (November 2020) . - p.1893-1901[article] Age-Specific Time Trends in Incidence Rates of Autism Spectrum Disorder Following Adaptation of DSM-5 and Other ASD-Related Regulatory Changes in Israel [texte imprimé] / Michael DAVIDOVITCH, Auteur ; Ortal SLOBODIN, Auteur ; Marc G. WEISSKOPF, Auteur ; Ran S. ROTEM, Auteur . - p.1893-1901.
Langues : Anglais (eng)
in Autism Research > 13-11 (November 2020) . - p.1893-1901
Mots-clés : Dsm age trends autism spectrum disorder incidence late diagnosis Index. décimale : PER Périodiques Résumé : We analyzed data on 879,029 children born in 1999-2017 from a large Israeli health fund to evaluate time-trends in incidence of autism spectrum disorder (ASD). This included examining possible effects associated with the adaptation of the DSM-5 criteria for ASD, and the implementation of regulatory changes affecting eligibility for ASD-related stipends and services. ASD cases were ascertained based on electronic medical records review, with complete verification of ASD case status. Results indicated a substantial increase in ASD incidence rate (IR) over time that was overall not appreciably affected by the above changes. Cumulative incidence through age 8 rose from 0.46% (boys: 0.73; girls: 0.18) in 2007 to 1.30% (boys: 2.12; girls: 0.45) in 2018. Age-specific analyzes indicated that the largest increase in IR occurred in toddlers and preschool children, with a more modest increase at older age groups. Results suggest that the rise in early diagnosed ASD does not stem from a downward shift in the distribution of ages at first diagnosis, but rather from early detection of cases not previously diagnosed. Findings highlight the need to expand research aimed at identifying exogenous factors that may underlie the rise in incidence, and to evaluate factors that may contribute to late diagnosis of some cases. Autism Res 2020, 13: 1893-1901. © 2020 International Society for Autism Research and Wiley Periodicals LLC LAY SUMMARY: In an analysis of nearly 900,000 Israeli children born in 1999-2017, we found that the incidence of autism spectrum disorder (ASD) increased significantly over time, especially among toddlers and preschool children but also at older age groups. We additionally observed that changes affecting diagnostic criteria for ASD and eligibility for ASD-related services did not appreciably affect these trends. Results highlight the need to continue research aimed at identifying factors causing this increase and reasons contributing to late diagnosis of some cases. En ligne : http://dx.doi.org/10.1002/aur.2420 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 Autism Spectrum Disorder: Incidence and Time Trends Over Two Decades in a Population-Based Birth Cohort / Scott M. MYERS in Journal of Autism and Developmental Disorders, 49-4 (April 2019)
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Titre : Autism Spectrum Disorder: Incidence and Time Trends Over Two Decades in a Population-Based Birth Cohort Type de document : texte imprimé Auteurs : Scott M. MYERS, Auteur ; Robert G. VOIGT, Auteur ; Robert C. COLLIGAN, Auteur ; Amy L. WEAVER, Auteur ; Curtis B. STORLIE, Auteur ; Ruth E. STOECKEL, Auteur ; John D. PORT, Auteur ; Slavica K. KATUSIC, Auteur Article en page(s) : p.1455-1474 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Epidemiology Incidence Time trends Index. décimale : PER Périodiques Résumé : We retrospectively identified autism spectrum disorder (ASD) incident cases among 31,220 individuals in a population-based birth cohort based on signs and symptoms uniformly abstracted from medical and educational records. Inclusive and narrow research definitions of ASD (ASD-RI and ASD-RN, respectively) were explored, along with clinical diagnoses of ASD (ASD-C) obtained from the records. The incidence of ASD-RI, ASD-RN, and ASD-C increased significantly from 1985 to 1998, then ASD-RI and ASD-RN plateaued while the rate of ASD-C continued to increase during 1998-2004. The rising incidence of research-defined ASD may reflect improved recognition and documentation of ASD signs and symptoms. Although the frequency of threshold ASD symptoms stabilized, the rate of ASD-C continued to increase, narrowing the gap between clinical ascertainment and symptom documentation. En ligne : https://dx.doi.org/10.1007/s10803-018-3834-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388
in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1455-1474[article] Autism Spectrum Disorder: Incidence and Time Trends Over Two Decades in a Population-Based Birth Cohort [texte imprimé] / Scott M. MYERS, Auteur ; Robert G. VOIGT, Auteur ; Robert C. COLLIGAN, Auteur ; Amy L. WEAVER, Auteur ; Curtis B. STORLIE, Auteur ; Ruth E. STOECKEL, Auteur ; John D. PORT, Auteur ; Slavica K. KATUSIC, Auteur . - p.1455-1474.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1455-1474
Mots-clés : Autism spectrum disorder Epidemiology Incidence Time trends Index. décimale : PER Périodiques Résumé : We retrospectively identified autism spectrum disorder (ASD) incident cases among 31,220 individuals in a population-based birth cohort based on signs and symptoms uniformly abstracted from medical and educational records. Inclusive and narrow research definitions of ASD (ASD-RI and ASD-RN, respectively) were explored, along with clinical diagnoses of ASD (ASD-C) obtained from the records. The incidence of ASD-RI, ASD-RN, and ASD-C increased significantly from 1985 to 1998, then ASD-RI and ASD-RN plateaued while the rate of ASD-C continued to increase during 1998-2004. The rising incidence of research-defined ASD may reflect improved recognition and documentation of ASD signs and symptoms. Although the frequency of threshold ASD symptoms stabilized, the rate of ASD-C continued to increase, narrowing the gap between clinical ascertainment and symptom documentation. En ligne : https://dx.doi.org/10.1007/s10803-018-3834-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 Brief Report: Cumulative Incidence of Autism Spectrum Disorder Before School Entry in a Thoroughly Screened Population / Daimei SASAYAMA in Journal of Autism and Developmental Disorders, 51-4 (April 2021)
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Titre : Brief Report: Cumulative Incidence of Autism Spectrum Disorder Before School Entry in a Thoroughly Screened Population Type de document : texte imprimé Auteurs : Daimei SASAYAMA, Auteur ; Tetsuya KUDO, Auteur ; Wakako KANEKO, Auteur ; Rie KUGE, Auteur ; Noriaki KOIZUMI, Auteur ; Tetsuo NOMIYAMA, Auteur ; Shinsuke WASHIZUKA, Auteur ; Hideo HONDA, Auteur Article en page(s) : p.1400-1405 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Epidemiology Incidence Mass screening Index. décimale : PER Périodiques Résumé : The present study aimed to identify the cumulative incidence of autism spectrum disorder (ASD) in a thoroughly screened population and to examine the behavioral and motor characteristics observed in children with ASD at the age of 18 months. Subjects were 1067 children who underwent a screening assessment for ASD at the routine 18-months health checkup. By the age of 6 years, 3.1% (4.3% of boys and 2.0% of girls) were diagnosed as having ASD by their attending pediatricians. Higher rate of difficulties in motor skills and social and communication skills had been reported in children with ASD at 18 months of age. This study showed that careful community-based screening system may be helpful in detecting ASD at early age. En ligne : http://dx.doi.org/10.1007/s10803-020-04619-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445
in Journal of Autism and Developmental Disorders > 51-4 (April 2021) . - p.1400-1405[article] Brief Report: Cumulative Incidence of Autism Spectrum Disorder Before School Entry in a Thoroughly Screened Population [texte imprimé] / Daimei SASAYAMA, Auteur ; Tetsuya KUDO, Auteur ; Wakako KANEKO, Auteur ; Rie KUGE, Auteur ; Noriaki KOIZUMI, Auteur ; Tetsuo NOMIYAMA, Auteur ; Shinsuke WASHIZUKA, Auteur ; Hideo HONDA, Auteur . - p.1400-1405.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-4 (April 2021) . - p.1400-1405
Mots-clés : Autism spectrum disorder Epidemiology Incidence Mass screening Index. décimale : PER Périodiques Résumé : The present study aimed to identify the cumulative incidence of autism spectrum disorder (ASD) in a thoroughly screened population and to examine the behavioral and motor characteristics observed in children with ASD at the age of 18 months. Subjects were 1067 children who underwent a screening assessment for ASD at the routine 18-months health checkup. By the age of 6 years, 3.1% (4.3% of boys and 2.0% of girls) were diagnosed as having ASD by their attending pediatricians. Higher rate of difficulties in motor skills and social and communication skills had been reported in children with ASD at 18 months of age. This study showed that careful community-based screening system may be helpful in detecting ASD at early age. En ligne : http://dx.doi.org/10.1007/s10803-020-04619-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445 Differences in Autism Spectrum Disorders Incidence by Sub-Populations in Israel 1992–2009: A Total Population Study / Raanan RAZ in Journal of Autism and Developmental Disorders, 45-4 (April 2015)
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PermalinkPrevalence and Incidence of Autism Spectrum Disorder in an Israeli Population / Michael DAVIDOVITCH in Journal of Autism and Developmental Disorders, 43-4 (April 2013)
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PermalinkThe prevalence and incidence of early-onset dementia among adults with autism spectrum disorder / Giacomo VIVANTI in Autism Research, 14-10 (October 2021)
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PermalinkTime Trends Over 16 Years in Incidence-Rates of Autism Spectrum Disorders Across the Lifespan Based on Nationwide Danish Register Data / Christina MOHR JENSEN in Journal of Autism and Developmental Disorders, 44-8 (August 2014)
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PermalinkChange in Autism Diagnoses Prior to and Following the Introduction of DSM-5 / Catherine A. BENT in Journal of Autism and Developmental Disorders, 47-1 (January 2017)
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