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Premature mortality in a population-based cohort of autistic adults in Canada / Yona LUNSKY in Autism Research, 15-8 (August 2022)
[article]
Titre : Premature mortality in a population-based cohort of autistic adults in Canada Type de document : Texte imprimé et/ou numérique Auteurs : Yona LUNSKY, Auteur ; Meng-Chuan LAI, Auteur ; Robert BALOGH, Auteur ; Hannah CHUNG, Auteur ; Anna DURBIN, Auteur ; Patrick JACHYRA, Auteur ; Ami TINT, Auteur ; Jonathan WEISS, Auteur ; Elizabeth LIN, Auteur Article en page(s) : p.1550-1559 Langues : Anglais (eng) Mots-clés : Adult Autism Spectrum Disorder/epidemiology Autistic Disorder/epidemiology Child Cohort Studies Developmental Disabilities/epidemiology Female Humans Infant, Newborn Male Mortality, Premature Ontario/epidemiology autism developmental disabilities premature mortality sex differences Index. décimale : PER Périodiques Résumé : Research from different countries suggests that autistic adults are more likely to die prematurely than non-autistic adults, but these studies do not always investigate male and female individuals separately and do not consider whether this pattern is unique to autistic people or is also an issue for people with other developmental disabilities. We examined premature mortality in autistic males and females (assigned at birth) in a population-based cohort, compared to males and females with and without other developmental disabilities. Using linked administrative health and social services population data from Ontario, Canada, age-matched males and females aged 19-65years were followed between 2010 and 2016, and causes of death were determined. Over the 6-year observation period, 330 of 42,607 persons (0.77%) in the group without developmental disabilities had died compared to 259 of 10,646 persons (2.43%) in the autism group and 419 of 10,615 persons (3.95%) in the other developmental disabilities group. Autistic males and females were more likely to die than non-autistic males (adjusted risk ratio, RR 3.13, 95%CI 2.58-3.79) and non-autistic females (adjusted RR 3.12, 95%CI 2.35-4.13) without developmental disabilities, but were less likely to die than adults with other developmental disabilities (males: adjusted RR 0.66, 95%CI 0.55-0.79; females: adjusted RR 0.55, 95%CI 0.43-0.71). Most common causes of death varied depending on a person's sex and diagnosis. Given the greater likelihood of premature mortality in adults with developmental disabilities including autism, greater attention and resources directed toward their health and social care are needed, tailored to their sex and diagnosis-informed needs. LAY SUMMARY: This study looked at how many autistic men and women died over 6years (2010-2016), along with how they died, and compared this to adults who did not have autism living in Ontario, Canada. It found that autistic men and women were more than three times as likely to die as people of the same age who did not have a developmental disability. However, adults with other developmental disabilities besides autism were even more likely to die than autistic adults. This means that we have to pay more attention and invest in better social and health care for autistic people, along with people who have other types of developmental disabilities. En ligne : http://dx.doi.org/10.1002/aur.2741 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483
in Autism Research > 15-8 (August 2022) . - p.1550-1559[article] Premature mortality in a population-based cohort of autistic adults in Canada [Texte imprimé et/ou numérique] / Yona LUNSKY, Auteur ; Meng-Chuan LAI, Auteur ; Robert BALOGH, Auteur ; Hannah CHUNG, Auteur ; Anna DURBIN, Auteur ; Patrick JACHYRA, Auteur ; Ami TINT, Auteur ; Jonathan WEISS, Auteur ; Elizabeth LIN, Auteur . - p.1550-1559.
Langues : Anglais (eng)
in Autism Research > 15-8 (August 2022) . - p.1550-1559
Mots-clés : Adult Autism Spectrum Disorder/epidemiology Autistic Disorder/epidemiology Child Cohort Studies Developmental Disabilities/epidemiology Female Humans Infant, Newborn Male Mortality, Premature Ontario/epidemiology autism developmental disabilities premature mortality sex differences Index. décimale : PER Périodiques Résumé : Research from different countries suggests that autistic adults are more likely to die prematurely than non-autistic adults, but these studies do not always investigate male and female individuals separately and do not consider whether this pattern is unique to autistic people or is also an issue for people with other developmental disabilities. We examined premature mortality in autistic males and females (assigned at birth) in a population-based cohort, compared to males and females with and without other developmental disabilities. Using linked administrative health and social services population data from Ontario, Canada, age-matched males and females aged 19-65years were followed between 2010 and 2016, and causes of death were determined. Over the 6-year observation period, 330 of 42,607 persons (0.77%) in the group without developmental disabilities had died compared to 259 of 10,646 persons (2.43%) in the autism group and 419 of 10,615 persons (3.95%) in the other developmental disabilities group. Autistic males and females were more likely to die than non-autistic males (adjusted risk ratio, RR 3.13, 95%CI 2.58-3.79) and non-autistic females (adjusted RR 3.12, 95%CI 2.35-4.13) without developmental disabilities, but were less likely to die than adults with other developmental disabilities (males: adjusted RR 0.66, 95%CI 0.55-0.79; females: adjusted RR 0.55, 95%CI 0.43-0.71). Most common causes of death varied depending on a person's sex and diagnosis. Given the greater likelihood of premature mortality in adults with developmental disabilities including autism, greater attention and resources directed toward their health and social care are needed, tailored to their sex and diagnosis-informed needs. LAY SUMMARY: This study looked at how many autistic men and women died over 6years (2010-2016), along with how they died, and compared this to adults who did not have autism living in Ontario, Canada. It found that autistic men and women were more than three times as likely to die as people of the same age who did not have a developmental disability. However, adults with other developmental disabilities besides autism were even more likely to die than autistic adults. This means that we have to pay more attention and invest in better social and health care for autistic people, along with people who have other types of developmental disabilities. En ligne : http://dx.doi.org/10.1002/aur.2741 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483 Primary Care Provider and Child Characteristics Associated with Age of Diagnosis of Autism Spectrum Disorder: A Population-Based Cohort Study / Ayesha SIDDIQUA in Journal of Autism and Developmental Disorders, 52-7 (July 2022)
[article]
Titre : Primary Care Provider and Child Characteristics Associated with Age of Diagnosis of Autism Spectrum Disorder: A Population-Based Cohort Study Type de document : Texte imprimé et/ou numérique Auteurs : Ayesha SIDDIQUA, Auteur ; Magdalena JANUS, Auteur ; Ronit MESTERMAN, Auteur ; Eric DUKU, Auteur ; Kathy GEORGIADES, Auteur ; Farah SAXENA, Auteur ; Haoyu ZHAO, Auteur ; Natasha R. SAUNDERS, Auteur Article en page(s) : p.2896-2910 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Child Cohort Studies Family Humans Ontario/epidemiology Primary Health Care Autism spectrum disorder Developmental disabilities Diagnosis Early development instrument Kindergarten Paediatricians Primary care Index. décimale : PER Périodiques Résumé : In a cohort of kindergarten children in Ontario, Canada with Autism Spectrum Disorder (ASD) (n=1522), we tested the association of age at ASD diagnosis and characteristics of (1) the child's primary care provider and, (2) the child using health administrative databases. We tested the association of primary care practice model and time from developmental delay identification to age at ASD diagnosis. Older age of diagnosis was associated with provider foreign training (vs. domestic) (adjusted Hazard Ratio [aHR] 1.17, 95% CI 1.03, 1.33) but not sex, care model, and years of practice. After developmental delay identification, children with paediatricians had longer time to diagnosis than children with providers in care models (aHR 0.68, 95% CI 0.54, 0.86). Findings can be used to inform primary care provider ASD training. En ligne : http://dx.doi.org/10.1007/s10803-021-05165-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477
in Journal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.2896-2910[article] Primary Care Provider and Child Characteristics Associated with Age of Diagnosis of Autism Spectrum Disorder: A Population-Based Cohort Study [Texte imprimé et/ou numérique] / Ayesha SIDDIQUA, Auteur ; Magdalena JANUS, Auteur ; Ronit MESTERMAN, Auteur ; Eric DUKU, Auteur ; Kathy GEORGIADES, Auteur ; Farah SAXENA, Auteur ; Haoyu ZHAO, Auteur ; Natasha R. SAUNDERS, Auteur . - p.2896-2910.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.2896-2910
Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Child Cohort Studies Family Humans Ontario/epidemiology Primary Health Care Autism spectrum disorder Developmental disabilities Diagnosis Early development instrument Kindergarten Paediatricians Primary care Index. décimale : PER Périodiques Résumé : In a cohort of kindergarten children in Ontario, Canada with Autism Spectrum Disorder (ASD) (n=1522), we tested the association of age at ASD diagnosis and characteristics of (1) the child's primary care provider and, (2) the child using health administrative databases. We tested the association of primary care practice model and time from developmental delay identification to age at ASD diagnosis. Older age of diagnosis was associated with provider foreign training (vs. domestic) (adjusted Hazard Ratio [aHR] 1.17, 95% CI 1.03, 1.33) but not sex, care model, and years of practice. After developmental delay identification, children with paediatricians had longer time to diagnosis than children with providers in care models (aHR 0.68, 95% CI 0.54, 0.86). Findings can be used to inform primary care provider ASD training. En ligne : http://dx.doi.org/10.1007/s10803-021-05165-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477