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2 recherche sur le mot-clé 'Pervasive developmental disorder-not otherwise specified (PDD-NOS)'
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ASD Symptom Severity in Adolescence of Individuals Diagnosed with PDD-NOS in Childhood: Stability and the Relation with Psychiatric Comorbidity and Societal Participation / A. LOUWERSE in Journal of Autism and Developmental Disorders, 45-12 (December 2015)
[article]
Titre : ASD Symptom Severity in Adolescence of Individuals Diagnosed with PDD-NOS in Childhood: Stability and the Relation with Psychiatric Comorbidity and Societal Participation Type de document : Texte imprimé et/ou numérique Auteurs : A. LOUWERSE, Auteur ; M. L. J. M. EUSSEN, Auteur ; J. VAN DER ENDE, Auteur ; P. F. A. DE NIJS, Auteur ; A. R. VAN GOOL, Auteur ; Linda P. DEKKER, Auteur ; C. VERHEIJ, Auteur ; F. VERHEIJ, Auteur ; F. C. VERHULST, Auteur ; K. GREAVES-LORD, Auteur Année de publication : 2015 Article en page(s) : p.3908-3918 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders (ASD) Pervasive developmental disorder-not otherwise specified (PDD-NOS) Comorbid psychiatric disorders Follow-up Autism Diagnostic Observation Schedule (ADOS-2) Symptom severity Societal functioning Index. décimale : PER Périodiques Résumé : The current 7-year follow-up study investigated: (1) the stability of ASD severity, and (2) associations of ASD severity in adolescence with (a) childhood and concurrent psychiatric comorbidity, and (b) concurrent societal functioning. The Autism Diagnostic Observation Schedule (ADOS) and the Diagnostic Interview Schedule for Children were administered in childhood (ages 6–12) and in adolescence (ages 12–20) to 72 individuals with a pervasive developmental disorder-not otherwise specified (PDD-NOS). ADOS calibrated severity scores showed a large stability (r = .51). Psychiatric comorbidity in childhood and adolescence were not associated with ASD severity in adolescence. Mental health care use (87 %) and special education needs were high (71 %). Reevaluation of ASD severity and psychiatric comorbidity later in life seem useful when PDD-NOS is diagnosed in childhood. En ligne : http://dx.doi.org/10.1007/s10803-015-2595-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273
in Journal of Autism and Developmental Disorders > 45-12 (December 2015) . - p.3908-3918[article] ASD Symptom Severity in Adolescence of Individuals Diagnosed with PDD-NOS in Childhood: Stability and the Relation with Psychiatric Comorbidity and Societal Participation [Texte imprimé et/ou numérique] / A. LOUWERSE, Auteur ; M. L. J. M. EUSSEN, Auteur ; J. VAN DER ENDE, Auteur ; P. F. A. DE NIJS, Auteur ; A. R. VAN GOOL, Auteur ; Linda P. DEKKER, Auteur ; C. VERHEIJ, Auteur ; F. VERHEIJ, Auteur ; F. C. VERHULST, Auteur ; K. GREAVES-LORD, Auteur . - 2015 . - p.3908-3918.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-12 (December 2015) . - p.3908-3918
Mots-clés : Autism spectrum disorders (ASD) Pervasive developmental disorder-not otherwise specified (PDD-NOS) Comorbid psychiatric disorders Follow-up Autism Diagnostic Observation Schedule (ADOS-2) Symptom severity Societal functioning Index. décimale : PER Périodiques Résumé : The current 7-year follow-up study investigated: (1) the stability of ASD severity, and (2) associations of ASD severity in adolescence with (a) childhood and concurrent psychiatric comorbidity, and (b) concurrent societal functioning. The Autism Diagnostic Observation Schedule (ADOS) and the Diagnostic Interview Schedule for Children were administered in childhood (ages 6–12) and in adolescence (ages 12–20) to 72 individuals with a pervasive developmental disorder-not otherwise specified (PDD-NOS). ADOS calibrated severity scores showed a large stability (r = .51). Psychiatric comorbidity in childhood and adolescence were not associated with ASD severity in adolescence. Mental health care use (87 %) and special education needs were high (71 %). Reevaluation of ASD severity and psychiatric comorbidity later in life seem useful when PDD-NOS is diagnosed in childhood. En ligne : http://dx.doi.org/10.1007/s10803-015-2595-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273 Common and unique multimodal covarying patterns in autism spectrum disorder subtypes / Shile QI in Molecular Autism, 11 (2020)
[article]
Titre : Common and unique multimodal covarying patterns in autism spectrum disorder subtypes Type de document : Texte imprimé et/ou numérique Auteurs : Shile QI, Auteur ; Robin MORRIS, Auteur ; Jessica A TURNER, Auteur ; Zening FU, Auteur ; Rongtao JIANG, Auteur ; Thomas P. DERAMUS, Auteur ; Dongmei ZHI, Auteur ; Vince D. CALHOUN, Auteur ; Jing SUI, Auteur Année de publication : 2020 Langues : Anglais (eng) Mots-clés : Asperger’s disorder Autism spectrum disorder Autistic disorder Heterogeneity Multimodal fusion Pervasive developmental disorder-not otherwise specified (PDD-NOS) Index. décimale : PER Périodiques Résumé : BACKGROUND: The heterogeneity inherent in autism spectrum disorder (ASD) presents a substantial challenge to diagnosis and precision treatment. Heterogeneity across biological etiologies, genetics, neural systems, neurocognitive attributes and clinical subtypes or phenotypes has been observed across individuals with ASD. METHODS: In this study, we aim to investigate the heterogeneity in ASD from a multimodal brain imaging perspective. The Autism Diagnostic Observation Schedule (ADOS) was used as a reference to guide functional and structural MRI fusion. DSM-IV-TR diagnosed Asperger's disorder (n?=?79), pervasive developmental disorder-not otherwise specified [PDD-NOS] (n?=?58) and Autistic disorder (n?=?92) from ABIDE II were used as discovery cohort, and ABIDE I (n?=?400) was used for replication. RESULTS: Dorsolateral prefrontal cortex and superior/middle temporal cortex are the primary common functional-structural covarying cortical brain areas shared among Asperger's, PDD-NOS and Autistic subgroups. Key differences among the three subtypes are negative functional features within subcortical brain areas, including negative putamen-parahippocampus fractional amplitude of low-frequency fluctuations (fALFF) unique to the Asperger's subtype; negative fALFF in anterior cingulate cortex unique to PDD-NOS subtype; and negative thalamus-amygdala-caudate fALFF unique to the Autistic subtype. Furthermore, each subtype-specific brain pattern is correlated with different ADOS subdomains, with social interaction as the common subdomain. The identified subtype-specific patterns are only predictive for ASD symptoms manifested in the corresponding subtypes, but not the other subtypes. CONCLUSIONS: Although ASD has a common neural basis with core deficits linked to social interaction, each ASD subtype is strongly linked to unique brain systems and subdomain symptoms, which may help to better understand the underlying mechanisms of ASD heterogeneity from a multimodal neuroimaging perspective. LIMITATIONS: This study is male based, which cannot be generalized to the female or the general ASD population. En ligne : http://dx.doi.org/10.1186/s13229-020-00397-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438
in Molecular Autism > 11 (2020)[article] Common and unique multimodal covarying patterns in autism spectrum disorder subtypes [Texte imprimé et/ou numérique] / Shile QI, Auteur ; Robin MORRIS, Auteur ; Jessica A TURNER, Auteur ; Zening FU, Auteur ; Rongtao JIANG, Auteur ; Thomas P. DERAMUS, Auteur ; Dongmei ZHI, Auteur ; Vince D. CALHOUN, Auteur ; Jing SUI, Auteur . - 2020.
Langues : Anglais (eng)
in Molecular Autism > 11 (2020)
Mots-clés : Asperger’s disorder Autism spectrum disorder Autistic disorder Heterogeneity Multimodal fusion Pervasive developmental disorder-not otherwise specified (PDD-NOS) Index. décimale : PER Périodiques Résumé : BACKGROUND: The heterogeneity inherent in autism spectrum disorder (ASD) presents a substantial challenge to diagnosis and precision treatment. Heterogeneity across biological etiologies, genetics, neural systems, neurocognitive attributes and clinical subtypes or phenotypes has been observed across individuals with ASD. METHODS: In this study, we aim to investigate the heterogeneity in ASD from a multimodal brain imaging perspective. The Autism Diagnostic Observation Schedule (ADOS) was used as a reference to guide functional and structural MRI fusion. DSM-IV-TR diagnosed Asperger's disorder (n?=?79), pervasive developmental disorder-not otherwise specified [PDD-NOS] (n?=?58) and Autistic disorder (n?=?92) from ABIDE II were used as discovery cohort, and ABIDE I (n?=?400) was used for replication. RESULTS: Dorsolateral prefrontal cortex and superior/middle temporal cortex are the primary common functional-structural covarying cortical brain areas shared among Asperger's, PDD-NOS and Autistic subgroups. Key differences among the three subtypes are negative functional features within subcortical brain areas, including negative putamen-parahippocampus fractional amplitude of low-frequency fluctuations (fALFF) unique to the Asperger's subtype; negative fALFF in anterior cingulate cortex unique to PDD-NOS subtype; and negative thalamus-amygdala-caudate fALFF unique to the Autistic subtype. Furthermore, each subtype-specific brain pattern is correlated with different ADOS subdomains, with social interaction as the common subdomain. The identified subtype-specific patterns are only predictive for ASD symptoms manifested in the corresponding subtypes, but not the other subtypes. CONCLUSIONS: Although ASD has a common neural basis with core deficits linked to social interaction, each ASD subtype is strongly linked to unique brain systems and subdomain symptoms, which may help to better understand the underlying mechanisms of ASD heterogeneity from a multimodal neuroimaging perspective. LIMITATIONS: This study is male based, which cannot be generalized to the female or the general ASD population. En ligne : http://dx.doi.org/10.1186/s13229-020-00397-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438