1 recherche sur le mot-clé 'Prenatal androgen exposure'

Associations of the digit ratio with adolescent behavior problems are inconsistent with an intrauterine androgenic origin / Allison L. SEELEY in Development and Psychopathology, 36-3 (August 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-3 (August 2024) . - p.1239-1248 Titre : Associations of the digit ratio with adolescent behavior problems are inconsistent with an intrauterine androgenic origin Type de document : texte imprimé Auteurs : Allison L. SEELEY, Auteur ; Mercedes MORA-PLAZAS, Auteur ; Henry OLIVEROS, Auteur ; Constanza MARIN, Auteur ; Eduardo VILLAMOR, Auteur Article en page(s) : p.1239-1248 Langues : Anglais (eng) Mots-clés : 2D:4D  Adolescence  Digit ratio  Externalizing behavior  Internalizing behavior  Prenatal androgen exposure Index. décimale : PER Périodiques Résumé : A low second-to-fourth digit ratio (2D:4D) is a purported biomarker of increased intrauterine androgenic exposure, presumably linked to postnatal behavior. We aimed to examine the associations between 2D:4D and adolescence behavior problems expected from high (externalizing and attention problems) or low (internalizing problems) prenatal androgen exposure. We conducted a cross-sectional study of 1042 Colombian schoolchildren aged 11-18 y. We examined whether caliper-assessed 2D:4D was associated with behavior problems per the Youth Self-Report questionnaire. Mean problem standardized score point differences were estimated between hand- and sex-specific quintiles of 2D:4D with use of multivariable linear regression. Lower right-hand 2D:4D was associated with decreased externalizing and internalizing behavior problem scores. Corresponding lowest-to-median quintile adjusted mean differences (95% CI) were 4.6 ( 7.5, 1.7) and 3.5 ( 6.4, 0.6) points in boys; and 3.4 ( 5.9, 0.9) and 3.5 ( 6.2, 0.8) points in girls. Lower right-hand 2D:4D was also related to less attention and thought problems in boys, and to less social problems among girls. Associations were nonlinear, apparent only below 2D:4D medians, and stronger with the right than the left hand. In conclusion, right-hand 2D:4D is related to behavior problems in adolescence in directions that are not fully consistent with an androgenic exposure origin. En ligne : https://dx.doi.org/10.1017/S0954579423000470 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538 [article] Associations of the digit ratio with adolescent behavior problems are inconsistent with an intrauterine androgenic origin [texte imprimé] / Allison L. SEELEY, Auteur ; Mercedes MORA-PLAZAS, Auteur ; Henry OLIVEROS, Auteur ; Constanza MARIN, Auteur ; Eduardo VILLAMOR, Auteur . - p.1239-1248. Langues : Anglais (eng) in Development and Psychopathology > 36-3 (August 2024) . - p.1239-1248 Mots-clés : 2D:4D  Adolescence  Digit ratio  Externalizing behavior  Internalizing behavior  Prenatal androgen exposure Index. décimale : PER Périodiques Résumé : A low second-to-fourth digit ratio (2D:4D) is a purported biomarker of increased intrauterine androgenic exposure, presumably linked to postnatal behavior. We aimed to examine the associations between 2D:4D and adolescence behavior problems expected from high (externalizing and attention problems) or low (internalizing problems) prenatal androgen exposure. We conducted a cross-sectional study of 1042 Colombian schoolchildren aged 11-18 y. We examined whether caliper-assessed 2D:4D was associated with behavior problems per the Youth Self-Report questionnaire. Mean problem standardized score point differences were estimated between hand- and sex-specific quintiles of 2D:4D with use of multivariable linear regression. Lower right-hand 2D:4D was associated with decreased externalizing and internalizing behavior problem scores. Corresponding lowest-to-median quintile adjusted mean differences (95% CI) were 4.6 ( 7.5, 1.7) and 3.5 ( 6.4, 0.6) points in boys; and 3.4 ( 5.9, 0.9) and 3.5 ( 6.2, 0.8) points in girls. Lower right-hand 2D:4D was also related to less attention and thought problems in boys, and to less social problems among girls. Associations were nonlinear, apparent only below 2D:4D medians, and stronger with the right than the left hand. In conclusion, right-hand 2D:4D is related to behavior problems in adolescence in directions that are not fully consistent with an androgenic exposure origin. En ligne : https://dx.doi.org/10.1017/S0954579423000470 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538