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The Association of Prenatal Vitamins and Folic Acid Supplement Intake with Odds of Autism Spectrum Disorder in a High-Risk Sibling Cohort, the Early Autism Risk Longitudinal Investigation (EARLI) / Katharine K. BRIEGER in Journal of Autism and Developmental Disorders, 52-6 (June 2022)
[article]
Titre : The Association of Prenatal Vitamins and Folic Acid Supplement Intake with Odds of Autism Spectrum Disorder in a High-Risk Sibling Cohort, the Early Autism Risk Longitudinal Investigation (EARLI) Type de document : Texte imprimé et/ou numérique Auteurs : Katharine K. BRIEGER, Auteur ; Kelly M. BAKULSKI, Auteur ; Celeste L. PEARCE, Auteur ; Ana BAYLIN, Auteur ; John F. DOU, Auteur ; Jason I. FEINBERG, Auteur ; Lisa A. CROEN, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Craig J. NEWSCHAFFER, Auteur ; M Daniele FALLIN, Auteur ; Rebecca J. SCHMIDT, Auteur Article en page(s) : p.2801-2811 Langues : Anglais (eng) Mots-clés : Autism Folic acid Pregnancy cohort Prenatal vitamins Index. décimale : PER Périodiques Résumé : We examined maternal prenatal vitamin use or supplemental folic acid intake during month one of pregnancy for association with autism spectrum disorder (ASD) in the Early Autism Risk Longitudinal Investigation, an enriched-risk pregnancy cohort. Total folic acid intake was calculated from monthly prenatal vitamins, multivitamins, and other supplement reports. Clinical assessments through age 3 years classified children as ASD (n=38) or non-ASD (n=153). In pregnancy month one, prenatal vitamin use (59.7%) was not significantly associated with odds of ASD (OR=0.70, 95%CI 0.32, 1.53). Sample size was limited and residual confounding was possible. Given the estimated effect sizes in this and previous work, prenatal vitamin intake during early pregnancy could be a clinically useful preventative measure for ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05110-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474
in Journal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2801-2811[article] The Association of Prenatal Vitamins and Folic Acid Supplement Intake with Odds of Autism Spectrum Disorder in a High-Risk Sibling Cohort, the Early Autism Risk Longitudinal Investigation (EARLI) [Texte imprimé et/ou numérique] / Katharine K. BRIEGER, Auteur ; Kelly M. BAKULSKI, Auteur ; Celeste L. PEARCE, Auteur ; Ana BAYLIN, Auteur ; John F. DOU, Auteur ; Jason I. FEINBERG, Auteur ; Lisa A. CROEN, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Craig J. NEWSCHAFFER, Auteur ; M Daniele FALLIN, Auteur ; Rebecca J. SCHMIDT, Auteur . - p.2801-2811.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2801-2811
Mots-clés : Autism Folic acid Pregnancy cohort Prenatal vitamins Index. décimale : PER Périodiques Résumé : We examined maternal prenatal vitamin use or supplemental folic acid intake during month one of pregnancy for association with autism spectrum disorder (ASD) in the Early Autism Risk Longitudinal Investigation, an enriched-risk pregnancy cohort. Total folic acid intake was calculated from monthly prenatal vitamins, multivitamins, and other supplement reports. Clinical assessments through age 3 years classified children as ASD (n=38) or non-ASD (n=153). In pregnancy month one, prenatal vitamin use (59.7%) was not significantly associated with odds of ASD (OR=0.70, 95%CI 0.32, 1.53). Sample size was limited and residual confounding was possible. Given the estimated effect sizes in this and previous work, prenatal vitamin intake during early pregnancy could be a clinically useful preventative measure for ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05110-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 Brief Report: Are Autistic-Behaviors in Children Related to Prenatal Vitamin Use and Maternal Whole Blood Folate Concentrations? / Joseph M. BRAUN in Journal of Autism and Developmental Disorders, 44-10 (October 2014)
[article]
Titre : Brief Report: Are Autistic-Behaviors in Children Related to Prenatal Vitamin Use and Maternal Whole Blood Folate Concentrations? Type de document : Texte imprimé et/ou numérique Auteurs : Joseph M. BRAUN, Auteur ; Tanya FROEHLICH, Auteur ; Amy E. KALKBRENNER, Auteur ; Christine M. PFEIFFER, Auteur ; Zia FAZILI, Auteur ; Kimberly YOLTON, Auteur ; Bruce P. LANPHEAR, Auteur Article en page(s) : p.2602-2607 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Folate Pregnancy Prenatal vitamins Index. décimale : PER Périodiques Résumé : Prenatal multivitamin/folic acid supplement use may reduce the risk of autism spectrum disorders. We investigated whether 2nd trimester prenatal vitamin use and maternal whole blood folate (WBF) concentrations were associated with Social Responsiveness Scale (SRS) scores at 4–5 years of age in a prospective cohort of 209 mother–child pairs. After confounder adjustment, children born to women taking prenatal vitamins weekly/daily (n = 179) had lower odds of clinically elevated SRS scores (odds ratio 0.26; 95 % confidence interval 0.08, 0.89) than those who rarely/never took them (n = 30). WBF concentrations were not associated with SRS scores. The lack of association between WBF and autistic-behaviors may be due to the timing of biomarker measures relative to critical periods of brain development, confounding, or other modifying factors. En ligne : http://dx.doi.org/10.1007/s10803-014-2114-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=240
in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2602-2607[article] Brief Report: Are Autistic-Behaviors in Children Related to Prenatal Vitamin Use and Maternal Whole Blood Folate Concentrations? [Texte imprimé et/ou numérique] / Joseph M. BRAUN, Auteur ; Tanya FROEHLICH, Auteur ; Amy E. KALKBRENNER, Auteur ; Christine M. PFEIFFER, Auteur ; Zia FAZILI, Auteur ; Kimberly YOLTON, Auteur ; Bruce P. LANPHEAR, Auteur . - p.2602-2607.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2602-2607
Mots-clés : Autism spectrum disorders Folate Pregnancy Prenatal vitamins Index. décimale : PER Périodiques Résumé : Prenatal multivitamin/folic acid supplement use may reduce the risk of autism spectrum disorders. We investigated whether 2nd trimester prenatal vitamin use and maternal whole blood folate (WBF) concentrations were associated with Social Responsiveness Scale (SRS) scores at 4–5 years of age in a prospective cohort of 209 mother–child pairs. After confounder adjustment, children born to women taking prenatal vitamins weekly/daily (n = 179) had lower odds of clinically elevated SRS scores (odds ratio 0.26; 95 % confidence interval 0.08, 0.89) than those who rarely/never took them (n = 30). WBF concentrations were not associated with SRS scores. The lack of association between WBF and autistic-behaviors may be due to the timing of biomarker measures relative to critical periods of brain development, confounding, or other modifying factors. En ligne : http://dx.doi.org/10.1007/s10803-014-2114-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=240