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All-cause mortality and suicide mortality in autistic individuals: An entire population longitudinal study in Taiwan / Shih-Jen TSAI in Autism, 27-8 (November 2023)
[article]
Titre : All-cause mortality and suicide mortality in autistic individuals: An entire population longitudinal study in Taiwan Type de document : Texte imprimé et/ou numérique Auteurs : Shih-Jen TSAI, Auteur ; Wen-Han CHANG, Auteur ; Chih-Ming CHENG, Auteur ; Chih-Sung LIANG, Auteur ; Ya-Mei BAI, Auteur ; Ju-Wei HSU, Auteur ; Kai-Lin HUANG, Auteur ; Tung-Ping SU, Auteur ; Tzeng-Ji CHEN, Auteur ; Mu-Hong CHEN, Auteur Article en page(s) : p.2496-2506 Mots-clés : autism mortality suicide Taiwan Index. décimale : PER Périodiques Résumé : Evidence suggests increased mortality rates among autistic individuals. However, risks of mortality, including natural-cause, suicide, and accident mortalities, among autistic individuals remain unclear. Among the entire Taiwanese population (N?=?29,253,529), between 2003 and 2017, 45,398 autistic individuals were identified and 1:4 matched to 181,592 non-autistic individuals based on birth year and sex. All-cause mortality, including natural-cause, accident, and suicide mortalities, was assessed from 2003 to 2017 between the two cohorts. Cox regression models were used to investigate the mortality risk between autistic and non-autistic individuals. Autistic individuals had increased likelihoods (hazard ratio, 95% confidence interval) of all-cause mortality (3.43, 3.00-3.92), natural-cause mortality (4.73, 3.99-5.60), and suicide mortality (3.67, 2.37-5.68) compared with non-autistic individuals. In particular, autistic males were more likely to die by suicide (hazard ratio: 3.81, 95% confidence interval: 2.37-6.13), and autistic females were more likely to die of accident (hazard ratio: 5.07, 95% confidence interval: 2.54-10.13) compared with non-autistic individuals. Appropriate and effective medical and mental health care is recommended for autistic individuals.Lay abstractOur study was the first population-based study in an Asian country to investigate the mortality rates among autistic individuals. Among the entire Taiwanese population (N?=?29,253,529), between 2003 and 2017, 45,398 autistic individuals were identified and 1:4 age-/sex-matched to 181,592 non-autistic individuals. We found that autistic individuals had increased risks of all-cause mortality, natural-cause mortality, and suicide mortality compared with non-autistic individuals. Furthermore, autistic males were more likely to die by suicide, and autistic females were more likely to die of accident compared with the non-autistic individuals. En ligne : http://dx.doi.org/10.1177/13623613231167287 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513
in Autism > 27-8 (November 2023) . - p.2496-2506[article] All-cause mortality and suicide mortality in autistic individuals: An entire population longitudinal study in Taiwan [Texte imprimé et/ou numérique] / Shih-Jen TSAI, Auteur ; Wen-Han CHANG, Auteur ; Chih-Ming CHENG, Auteur ; Chih-Sung LIANG, Auteur ; Ya-Mei BAI, Auteur ; Ju-Wei HSU, Auteur ; Kai-Lin HUANG, Auteur ; Tung-Ping SU, Auteur ; Tzeng-Ji CHEN, Auteur ; Mu-Hong CHEN, Auteur . - p.2496-2506.
in Autism > 27-8 (November 2023) . - p.2496-2506
Mots-clés : autism mortality suicide Taiwan Index. décimale : PER Périodiques Résumé : Evidence suggests increased mortality rates among autistic individuals. However, risks of mortality, including natural-cause, suicide, and accident mortalities, among autistic individuals remain unclear. Among the entire Taiwanese population (N?=?29,253,529), between 2003 and 2017, 45,398 autistic individuals were identified and 1:4 matched to 181,592 non-autistic individuals based on birth year and sex. All-cause mortality, including natural-cause, accident, and suicide mortalities, was assessed from 2003 to 2017 between the two cohorts. Cox regression models were used to investigate the mortality risk between autistic and non-autistic individuals. Autistic individuals had increased likelihoods (hazard ratio, 95% confidence interval) of all-cause mortality (3.43, 3.00-3.92), natural-cause mortality (4.73, 3.99-5.60), and suicide mortality (3.67, 2.37-5.68) compared with non-autistic individuals. In particular, autistic males were more likely to die by suicide (hazard ratio: 3.81, 95% confidence interval: 2.37-6.13), and autistic females were more likely to die of accident (hazard ratio: 5.07, 95% confidence interval: 2.54-10.13) compared with non-autistic individuals. Appropriate and effective medical and mental health care is recommended for autistic individuals.Lay abstractOur study was the first population-based study in an Asian country to investigate the mortality rates among autistic individuals. Among the entire Taiwanese population (N?=?29,253,529), between 2003 and 2017, 45,398 autistic individuals were identified and 1:4 age-/sex-matched to 181,592 non-autistic individuals. We found that autistic individuals had increased risks of all-cause mortality, natural-cause mortality, and suicide mortality compared with non-autistic individuals. Furthermore, autistic males were more likely to die by suicide, and autistic females were more likely to die of accident compared with the non-autistic individuals. En ligne : http://dx.doi.org/10.1177/13623613231167287 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513 Assessing Autistic Traits in a Taiwan Preschool Population: Cross-Cultural Validation of the Social Responsiveness Scale (SRS) / Jessica WANG in Journal of Autism and Developmental Disorders, 42-11 (November 2012)
[article]
Titre : Assessing Autistic Traits in a Taiwan Preschool Population: Cross-Cultural Validation of the Social Responsiveness Scale (SRS) Type de document : Texte imprimé et/ou numérique Auteurs : Jessica WANG, Auteur ; Li-Ching LEE, Auteur ; Ying-Sheue CHEN, Auteur ; Ju-Wei HSU, Auteur Année de publication : 2012 Article en page(s) : p.2450-2459 Langues : Anglais (eng) Mots-clés : SRS Taiwan Cross-cultural Validity Autism spectrum disorder Index. décimale : PER Périodiques Résumé : The cross-cultural validity of the Mandarin-adaptation of the social responsiveness scale (SRS) was examined in a sample of N = 307 participants in Taiwan, 140 typically developing and 167 with clinically-diagnosed developmental disorders. This scale is an autism assessment tool that provides a quantitative rather than categorical measure of social impairment in the general population. SRS total and subscale scores distinguished significantly between autism spectrum disorder and other developmental disorders ( p < 0.01). Total SRS scores and sensitivity and specificity of the scale for diagnosing developmental disorders in the Taiwan study were similar to those observed in Western studies. These findings support the cross-cultural validity of the SRS scale for detecting autistic traits and for distinguishing between autism and other neuropsychiatric conditions. En ligne : http://dx.doi.org/10.1007/s10803-012-1499-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=183
in Journal of Autism and Developmental Disorders > 42-11 (November 2012) . - p.2450-2459[article] Assessing Autistic Traits in a Taiwan Preschool Population: Cross-Cultural Validation of the Social Responsiveness Scale (SRS) [Texte imprimé et/ou numérique] / Jessica WANG, Auteur ; Li-Ching LEE, Auteur ; Ying-Sheue CHEN, Auteur ; Ju-Wei HSU, Auteur . - 2012 . - p.2450-2459.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-11 (November 2012) . - p.2450-2459
Mots-clés : SRS Taiwan Cross-cultural Validity Autism spectrum disorder Index. décimale : PER Périodiques Résumé : The cross-cultural validity of the Mandarin-adaptation of the social responsiveness scale (SRS) was examined in a sample of N = 307 participants in Taiwan, 140 typically developing and 167 with clinically-diagnosed developmental disorders. This scale is an autism assessment tool that provides a quantitative rather than categorical measure of social impairment in the general population. SRS total and subscale scores distinguished significantly between autism spectrum disorder and other developmental disorders ( p < 0.01). Total SRS scores and sensitivity and specificity of the scale for diagnosing developmental disorders in the Taiwan study were similar to those observed in Western studies. These findings support the cross-cultural validity of the SRS scale for detecting autistic traits and for distinguishing between autism and other neuropsychiatric conditions. En ligne : http://dx.doi.org/10.1007/s10803-012-1499-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=183 Changes in clinical presentation of children with autistic disorder, at an autism clinic in Taiwan from 1987 to 1995 / Wen-Che TSAI in Research in Autism Spectrum Disorders, 7-12 (December 2013)
[article]
Titre : Changes in clinical presentation of children with autistic disorder, at an autism clinic in Taiwan from 1987 to 1995 Type de document : Texte imprimé et/ou numérique Auteurs : Wen-Che TSAI, Auteur ; Wei-Tsuen SOONG, Auteur ; Wei-Chu CHIE, Auteur Article en page(s) : p.1501-1508 Langues : Anglais (eng) Mots-clés : Autistic disorder Child mental health Taiwan Index. décimale : PER Périodiques Résumé : Abstract Autistic disorder was originally viewed as a distinct, rare, and severe childhood mental disorder that caused life-long disability. However, since the late 1990s autistic disorder was found to have a high prevalence rate and to affect children on a spectrum from mild to severe dysfunction. The purpose of this retrospective, descriptive study was to examine changes in the characteristics of patients with autistic disorder in Taiwan from 1987 to 1995. To that end, we examined the characteristics, age at diagnosis, symptoms, and developmental condition of affected children and the educational background of their parents who visited an autism clinic at the children's mental health center of a medical center in Taipei. This clinic was the first, largest, and for many years the only autistic disorder clinic in Taiwan. Across the 9-year study period, we observed trends in decreasing age at first visit, increasing age at assessment, rising maternal educational level, lessening autistic disorder symptomatology, and increasing developmental quotients. These changes may have been due to improved diagnostic criteria, government policy, and healthcare professionals’ and parents’ increased awareness of autistic disorder. Clinical implications and related policy making toward these changes are proposed. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.09.014 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219
in Research in Autism Spectrum Disorders > 7-12 (December 2013) . - p.1501-1508[article] Changes in clinical presentation of children with autistic disorder, at an autism clinic in Taiwan from 1987 to 1995 [Texte imprimé et/ou numérique] / Wen-Che TSAI, Auteur ; Wei-Tsuen SOONG, Auteur ; Wei-Chu CHIE, Auteur . - p.1501-1508.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 7-12 (December 2013) . - p.1501-1508
Mots-clés : Autistic disorder Child mental health Taiwan Index. décimale : PER Périodiques Résumé : Abstract Autistic disorder was originally viewed as a distinct, rare, and severe childhood mental disorder that caused life-long disability. However, since the late 1990s autistic disorder was found to have a high prevalence rate and to affect children on a spectrum from mild to severe dysfunction. The purpose of this retrospective, descriptive study was to examine changes in the characteristics of patients with autistic disorder in Taiwan from 1987 to 1995. To that end, we examined the characteristics, age at diagnosis, symptoms, and developmental condition of affected children and the educational background of their parents who visited an autism clinic at the children's mental health center of a medical center in Taipei. This clinic was the first, largest, and for many years the only autistic disorder clinic in Taiwan. Across the 9-year study period, we observed trends in decreasing age at first visit, increasing age at assessment, rising maternal educational level, lessening autistic disorder symptomatology, and increasing developmental quotients. These changes may have been due to improved diagnostic criteria, government policy, and healthcare professionals’ and parents’ increased awareness of autistic disorder. Clinical implications and related policy making toward these changes are proposed. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.09.014 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219 Explaining and Selecting Treatments for Autism: Parental Explanatory Models in Taiwan / Yea-Ing Lotus SHYU in Journal of Autism and Developmental Disorders, 40-11 (November 2010)
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Titre : Explaining and Selecting Treatments for Autism: Parental Explanatory Models in Taiwan Type de document : Texte imprimé et/ou numérique Auteurs : Yea-Ing Lotus SHYU, Auteur ; Jia-Ling TSAI, Auteur ; Wen-Che TSAI, Auteur Année de publication : 2010 Article en page(s) : p.1323-1331 Langues : Anglais (eng) Mots-clés : Taiwan Autism Parental explanatory model Treatment selection Etiology Help seeking Index. décimale : PER Périodiques Résumé : Parental explanatory models about autism influence the type of therapy a child receives, the child’s well-being, and the parents’ own psychological adaptation. This qualitative study explored explanatory models used by parents of children with autism. In-depth interviews were conducted with 13 parents of children with autism from a medical center in Taiwan. Despite high educational background, most of these parents attributed their child’s autism to both biomedical and supernatural etiologies without apparent conflicts. These parents chose a wide variety of treatment strategies, including biomedical and alternative treatments, which often created time/energy pressures and financial burden, and were influenced by parents’ cause attribution. Parents’ illness explanations influence their treatment selections and need to be understood and accepted by health care providers. En ligne : http://dx.doi.org/10.1007/s10803-010-0991-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113
in Journal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1323-1331[article] Explaining and Selecting Treatments for Autism: Parental Explanatory Models in Taiwan [Texte imprimé et/ou numérique] / Yea-Ing Lotus SHYU, Auteur ; Jia-Ling TSAI, Auteur ; Wen-Che TSAI, Auteur . - 2010 . - p.1323-1331.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1323-1331
Mots-clés : Taiwan Autism Parental explanatory model Treatment selection Etiology Help seeking Index. décimale : PER Périodiques Résumé : Parental explanatory models about autism influence the type of therapy a child receives, the child’s well-being, and the parents’ own psychological adaptation. This qualitative study explored explanatory models used by parents of children with autism. In-depth interviews were conducted with 13 parents of children with autism from a medical center in Taiwan. Despite high educational background, most of these parents attributed their child’s autism to both biomedical and supernatural etiologies without apparent conflicts. These parents chose a wide variety of treatment strategies, including biomedical and alternative treatments, which often created time/energy pressures and financial burden, and were influenced by parents’ cause attribution. Parents’ illness explanations influence their treatment selections and need to be understood and accepted by health care providers. En ligne : http://dx.doi.org/10.1007/s10803-010-0991-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113 A qualitative study exploring the attitudes toward prenatal genetic testing for autism spectrum disorders among parents of affected children in Taiwan / Shixi ZHAO in Research in Autism Spectrum Disorders, 48 (April 2018)
[article]
Titre : A qualitative study exploring the attitudes toward prenatal genetic testing for autism spectrum disorders among parents of affected children in Taiwan Type de document : Texte imprimé et/ou numérique Auteurs : Shixi ZHAO, Auteur ; Chen-Hui WANG, Auteur ; Tse-Yang HUANG, Auteur ; Yann-Jang CHEN, Auteur ; Ching-Hua HSIAO, Auteur ; Chie-Chien TSENG, Auteur ; Lei XU, Auteur ; Lei-Shih CHEN, Auteur Article en page(s) : p.36-43 Langues : Anglais (eng) Mots-clés : Autism Parents Prenatal genetic testing Abortion Taiwan Index. décimale : PER Périodiques Résumé : Background Prenatal genetic testing (PGT) for Autism Spectrum Disorders (ASD) raises more complex ethical, legal, and social implications in Taiwan than in Western countries due to policy-related, practical, cultural, and familial reasons. This first qualitative study examines attitudes towards PGT for ASD among Taiwanese parents of children with ASD – an elevated risk group for having another affected child, and one that is mostly likely to be impacted by PGT for ASD. Methods We conducted in-depth, face-to-face, individual, semi-structured interviews with 39 parents of children with ASD from various ASD organizations in Taiwan. Results Most parents favored PGT for ASD mainly for terminating the affected pregnancy and receiving early intervention and treatment. Less than one-third of participants was against PGT for ASD due to perceived no value for this testing, contradiction with religion and/or personal beliefs, doubt of the test’s accuracy, or concerns about the negative consequences of the testing. Conclusion The majority of Taiwanese parents of children with ASD in this study supported PGT for ASD. Guidelines and regulations should be developed to regulate the provision and quality of this testing. Genetic counseling should also be recommended to parents of children with ASD in Taiwan. En ligne : https://doi.org/10.1016/j.rasd.2018.01.006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=340
in Research in Autism Spectrum Disorders > 48 (April 2018) . - p.36-43[article] A qualitative study exploring the attitudes toward prenatal genetic testing for autism spectrum disorders among parents of affected children in Taiwan [Texte imprimé et/ou numérique] / Shixi ZHAO, Auteur ; Chen-Hui WANG, Auteur ; Tse-Yang HUANG, Auteur ; Yann-Jang CHEN, Auteur ; Ching-Hua HSIAO, Auteur ; Chie-Chien TSENG, Auteur ; Lei XU, Auteur ; Lei-Shih CHEN, Auteur . - p.36-43.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 48 (April 2018) . - p.36-43
Mots-clés : Autism Parents Prenatal genetic testing Abortion Taiwan Index. décimale : PER Périodiques Résumé : Background Prenatal genetic testing (PGT) for Autism Spectrum Disorders (ASD) raises more complex ethical, legal, and social implications in Taiwan than in Western countries due to policy-related, practical, cultural, and familial reasons. This first qualitative study examines attitudes towards PGT for ASD among Taiwanese parents of children with ASD – an elevated risk group for having another affected child, and one that is mostly likely to be impacted by PGT for ASD. Methods We conducted in-depth, face-to-face, individual, semi-structured interviews with 39 parents of children with ASD from various ASD organizations in Taiwan. Results Most parents favored PGT for ASD mainly for terminating the affected pregnancy and receiving early intervention and treatment. Less than one-third of participants was against PGT for ASD due to perceived no value for this testing, contradiction with religion and/or personal beliefs, doubt of the test’s accuracy, or concerns about the negative consequences of the testing. Conclusion The majority of Taiwanese parents of children with ASD in this study supported PGT for ASD. Guidelines and regulations should be developed to regulate the provision and quality of this testing. Genetic counseling should also be recommended to parents of children with ASD in Taiwan. En ligne : https://doi.org/10.1016/j.rasd.2018.01.006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=340 Validation of the Mandarin Chinese version of the Autism Diagnostic Observation Schedule-2 for autism spectrum disorder / Mu-Hong CHEN in Research in Autism Spectrum Disorders, 105 (July 2023)
PermalinkDevelopment of T-STAT for Early Autism Screening / Chung-Hsin CHIANG in Journal of Autism and Developmental Disorders, 43-5 (May 2013)
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