Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
4 recherche sur le mot-clé 'auditory brainstem response'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
Autism spectrum disorders and the amplitude of auditory brainstem response wave I / Mariline SANTOS in Autism Research, 10-7 (July 2017)
[article]
Titre : Autism spectrum disorders and the amplitude of auditory brainstem response wave I Type de document : Texte imprimé et/ou numérique Auteurs : Mariline SANTOS, Auteur ; Cristina MARQUES, Auteur ; Ana NÓBREGA PINTO, Auteur ; Raquel FERNANDES, Auteur ; Miguel Bebiano COUTINHO, Auteur ; Cecília ALMEIDA E SOUSA, Auteur Article en page(s) : p.1300-1305 Langues : Anglais (eng) Mots-clés : auditory brainstem response autism spectrum disorders hearing Index. décimale : PER Périodiques Résumé : To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case–control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I–III, III–IV, and I–V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case–control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. En ligne : http://dx.doi.org/10.1002/aur.1771 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310
in Autism Research > 10-7 (July 2017) . - p.1300-1305[article] Autism spectrum disorders and the amplitude of auditory brainstem response wave I [Texte imprimé et/ou numérique] / Mariline SANTOS, Auteur ; Cristina MARQUES, Auteur ; Ana NÓBREGA PINTO, Auteur ; Raquel FERNANDES, Auteur ; Miguel Bebiano COUTINHO, Auteur ; Cecília ALMEIDA E SOUSA, Auteur . - p.1300-1305.
Langues : Anglais (eng)
in Autism Research > 10-7 (July 2017) . - p.1300-1305
Mots-clés : auditory brainstem response autism spectrum disorders hearing Index. décimale : PER Périodiques Résumé : To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case–control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I–III, III–IV, and I–V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case–control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. En ligne : http://dx.doi.org/10.1002/aur.1771 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310 Prolonged auditory brainstem responses in infants with autism / Oren MIRON in Autism Research, 9-6 (June 2016)
[article]
Titre : Prolonged auditory brainstem responses in infants with autism Type de document : Texte imprimé et/ou numérique Auteurs : Oren MIRON, Auteur ; Daphne ARI-EVEN ROTH, Auteur ; Lidia V. GABIS, Auteur ; Yael HENKIN, Auteur ; Shahar SHEFER, Auteur ; Ilan DINSTEIN, Auteur ; Ronny GEVA, Auteur Article en page(s) : p.689-695 Langues : Anglais (eng) Mots-clés : autism spectrum disorder auditory brainstem response hearing Index. décimale : PER Périodiques Résumé : Numerous studies have attempted to identify early physiological abnormalities in infants and toddlers who later develop autism spectrum disorder (ASD). One potential measure of early neurophysiology is the auditory brainstem response (ABR), which has been reported to exhibit prolonged latencies in children with ASD. We examined whether prolonged ABR latencies appear in infancy, before the onset of ASD symptoms, and irrespective of hearing thresholds. To determine how early in development these differences appear, we retrospectively examined clinical ABR recordings of infants who were later diagnosed with ASD. Of the 118 children in the participant pool, 48 were excluded due to elevated ABR thresholds, genetic aberrations, or old testing age, leaving a sample of 70 children: 30 of which were tested at 0–3 months, and 40 were tested at toddlerhood (1.5–3.5 years). In the infant group, the ABR wave-V was significantly prolonged in those who later developed ASD as compared with case-matched controls (n?=?30). Classification of infants who later developed ASD and case-matched controls using this measure enabled accurate identification of ASD infants with 80% specificity and 70% sensitivity. In the group of toddlers with ASD, absolute and interpeak latencies were prolonged compared to clinical norms. Findings indicate that ABR latencies are significantly prolonged in infants who are later diagnosed with ASD irrespective of their hearing thresholds; suggesting that abnormal responses might be detected soon after birth. Further research is needed to determine if ABR might be a valid marker for ASD risk. Autism Res 2016, 9: 689–695. © 2015 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research En ligne : http://dx.doi.org/10.1002/aur.1561 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290
in Autism Research > 9-6 (June 2016) . - p.689-695[article] Prolonged auditory brainstem responses in infants with autism [Texte imprimé et/ou numérique] / Oren MIRON, Auteur ; Daphne ARI-EVEN ROTH, Auteur ; Lidia V. GABIS, Auteur ; Yael HENKIN, Auteur ; Shahar SHEFER, Auteur ; Ilan DINSTEIN, Auteur ; Ronny GEVA, Auteur . - p.689-695.
Langues : Anglais (eng)
in Autism Research > 9-6 (June 2016) . - p.689-695
Mots-clés : autism spectrum disorder auditory brainstem response hearing Index. décimale : PER Périodiques Résumé : Numerous studies have attempted to identify early physiological abnormalities in infants and toddlers who later develop autism spectrum disorder (ASD). One potential measure of early neurophysiology is the auditory brainstem response (ABR), which has been reported to exhibit prolonged latencies in children with ASD. We examined whether prolonged ABR latencies appear in infancy, before the onset of ASD symptoms, and irrespective of hearing thresholds. To determine how early in development these differences appear, we retrospectively examined clinical ABR recordings of infants who were later diagnosed with ASD. Of the 118 children in the participant pool, 48 were excluded due to elevated ABR thresholds, genetic aberrations, or old testing age, leaving a sample of 70 children: 30 of which were tested at 0–3 months, and 40 were tested at toddlerhood (1.5–3.5 years). In the infant group, the ABR wave-V was significantly prolonged in those who later developed ASD as compared with case-matched controls (n?=?30). Classification of infants who later developed ASD and case-matched controls using this measure enabled accurate identification of ASD infants with 80% specificity and 70% sensitivity. In the group of toddlers with ASD, absolute and interpeak latencies were prolonged compared to clinical norms. Findings indicate that ABR latencies are significantly prolonged in infants who are later diagnosed with ASD irrespective of their hearing thresholds; suggesting that abnormal responses might be detected soon after birth. Further research is needed to determine if ABR might be a valid marker for ASD risk. Autism Res 2016, 9: 689–695. © 2015 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research En ligne : http://dx.doi.org/10.1002/aur.1561 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 Neonatal Brainstem Function and 4-Month Arousal-Modulated Attention Are Jointly Associated With Autism / Ira L. COHEN in Autism Research, 6-1 (February 2013)
[article]
Titre : Neonatal Brainstem Function and 4-Month Arousal-Modulated Attention Are Jointly Associated With Autism Type de document : Texte imprimé et/ou numérique Auteurs : Ira L. COHEN, Auteur ; Judith M. GARDNER, Auteur ; Bernard Z. KARMEL, Auteur ; Ha T. T. PHAN, Auteur ; Phyllis KITTLER, Auteur ; Tina Rovito GOMEZ, Auteur ; Maripaz G. GONZALEZ, Auteur ; Elizabeth M. LENNON, Auteur ; Santosh PARAB, Auteur ; Anthony BARONE, Auteur Année de publication : 2013 Article en page(s) : p.11-22 Langues : Anglais (eng) Mots-clés : auditory brainstem response infancy attention arousal repetitive and ritualistic behaviors autism spectrum disorder Index. décimale : PER Périodiques Résumé : The authors evaluated the contribution of initially abnormal neonatal auditory brainstem responses (ABRs) and 4-month arousal-modulated attention visual preference to later autism spectrum disorder (ASD) behaviors in neonatal intensive care unit (NICU) graduates. A longitudinal study design was used to compare NICU graduates with normal ABRs (n?=?28) to those with initially abnormal ABRs (n?=?46) that later resolved. At 4 months postterm age, visual preference (measured after feeding) for a random check pattern flashing at 1, 3, or 8?Hz and gestational age (GA) served as additional predictors. Outcome measures were PDD Behavior Inventory (PDDBI) scores at 3.4 years (standard deviation?=?1.2), and developmental quotients (DQ) obtained around the same age with the Griffiths Mental Development Scales (GMDS). Preferences for higher rates of stimulation at 4 months were highly correlated with PDDBI scores (all P-values??0.01) and the GMDS Hearing and Speech DQ, but only in those with initially abnormal ABRs. Effects were strongest for a PDDBI social competence measure most associated with a diagnosis of autism. For those with abnormal ABRs, increases in preference for higher rates of stimulation as infants were linked to nonlinear increases in severity of ASD at 3 years and to an ASD diagnosis. Abnormal ABRs were associated with later reports of repetitive and ritualistic behaviors irrespective of 4-month preference for stimulation. The joint occurrence of initially abnormal neonatal ABRs and preference for more stimulation at 4 months, both indices of early brainstem dysfunction, may be a marker for the development of autism in this cohort. En ligne : http://dx.doi.org/10.1002/aur.1259 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192
in Autism Research > 6-1 (February 2013) . - p.11-22[article] Neonatal Brainstem Function and 4-Month Arousal-Modulated Attention Are Jointly Associated With Autism [Texte imprimé et/ou numérique] / Ira L. COHEN, Auteur ; Judith M. GARDNER, Auteur ; Bernard Z. KARMEL, Auteur ; Ha T. T. PHAN, Auteur ; Phyllis KITTLER, Auteur ; Tina Rovito GOMEZ, Auteur ; Maripaz G. GONZALEZ, Auteur ; Elizabeth M. LENNON, Auteur ; Santosh PARAB, Auteur ; Anthony BARONE, Auteur . - 2013 . - p.11-22.
Langues : Anglais (eng)
in Autism Research > 6-1 (February 2013) . - p.11-22
Mots-clés : auditory brainstem response infancy attention arousal repetitive and ritualistic behaviors autism spectrum disorder Index. décimale : PER Périodiques Résumé : The authors evaluated the contribution of initially abnormal neonatal auditory brainstem responses (ABRs) and 4-month arousal-modulated attention visual preference to later autism spectrum disorder (ASD) behaviors in neonatal intensive care unit (NICU) graduates. A longitudinal study design was used to compare NICU graduates with normal ABRs (n?=?28) to those with initially abnormal ABRs (n?=?46) that later resolved. At 4 months postterm age, visual preference (measured after feeding) for a random check pattern flashing at 1, 3, or 8?Hz and gestational age (GA) served as additional predictors. Outcome measures were PDD Behavior Inventory (PDDBI) scores at 3.4 years (standard deviation?=?1.2), and developmental quotients (DQ) obtained around the same age with the Griffiths Mental Development Scales (GMDS). Preferences for higher rates of stimulation at 4 months were highly correlated with PDDBI scores (all P-values??0.01) and the GMDS Hearing and Speech DQ, but only in those with initially abnormal ABRs. Effects were strongest for a PDDBI social competence measure most associated with a diagnosis of autism. For those with abnormal ABRs, increases in preference for higher rates of stimulation as infants were linked to nonlinear increases in severity of ASD at 3 years and to an ASD diagnosis. Abnormal ABRs were associated with later reports of repetitive and ritualistic behaviors irrespective of 4-month preference for stimulation. The joint occurrence of initially abnormal neonatal ABRs and preference for more stimulation at 4 months, both indices of early brainstem dysfunction, may be a marker for the development of autism in this cohort. En ligne : http://dx.doi.org/10.1002/aur.1259 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192 Audiometric Profiles in Autism Spectrum Disorders: Does Subclinical Hearing Loss Impact Communication? / Carly DEMOPOULOS in Autism Research, 9-1 (January 2016)
[article]
Titre : Audiometric Profiles in Autism Spectrum Disorders: Does Subclinical Hearing Loss Impact Communication? Type de document : Texte imprimé et/ou numérique Auteurs : Carly DEMOPOULOS, Auteur ; Jeffrey David LEWINE, Auteur Article en page(s) : p.107-120 Langues : Anglais (eng) Mots-clés : autism audiology communication hearing auditory brainstem response Index. décimale : PER Périodiques Résumé : Rates of hearing impairment in individuals with Autism Spectrum Disorders (ASD) are higher than those reported in the general population. Although ASD is not caused by hearing impairment, it may exacerbate symptomatology. Participants with ASD (N?=?60) and typically developing peers (N?=?16) aged 5–18 years underwent a comprehensive audiological screening (pure tone audiometry, uncomfortable loudness level, tympanometry, acoustic reflexes, distortion product otoacoustic emissions, and auditory brainstem response) and assessment of communication abilities (expressive/receptive language, articulation, phonological awareness, and vocal affect recognition). Incidence of abnormal findings on at least one measure of audiological functioning was higher for the ASD group (55%) than controls (14.9%) or the general population estimate (6%). The presence of sound sensitivity was also considerably higher for the ASD group (37%) compared with controls (0%) or general population estimates (8–15%). When participants with ASD were dichotomized into groups with and without evidence of clinical audiological abnormality, no significant differences were identified on measures of communication; however, results of correlational analyses indicated that variability in hearing thresholds at middle range frequencies (2000 Hz) was significantly related to performance on all measures of speech articulation and language after correction for multiple comparisons (r?=??0.48 to r?=??0.53, P? 0.0045). These findings suggest that dichotomized classification of clinical audiology may not be sufficient to understand the role of subclinical hearing loss in ASD symptomatology and that treatment studies for mild/subclinical hearing loss in this population may be worthwhile. En ligne : http://dx.doi.org/10.1002/aur.1495 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282
in Autism Research > 9-1 (January 2016) . - p.107-120[article] Audiometric Profiles in Autism Spectrum Disorders: Does Subclinical Hearing Loss Impact Communication? [Texte imprimé et/ou numérique] / Carly DEMOPOULOS, Auteur ; Jeffrey David LEWINE, Auteur . - p.107-120.
Langues : Anglais (eng)
in Autism Research > 9-1 (January 2016) . - p.107-120
Mots-clés : autism audiology communication hearing auditory brainstem response Index. décimale : PER Périodiques Résumé : Rates of hearing impairment in individuals with Autism Spectrum Disorders (ASD) are higher than those reported in the general population. Although ASD is not caused by hearing impairment, it may exacerbate symptomatology. Participants with ASD (N?=?60) and typically developing peers (N?=?16) aged 5–18 years underwent a comprehensive audiological screening (pure tone audiometry, uncomfortable loudness level, tympanometry, acoustic reflexes, distortion product otoacoustic emissions, and auditory brainstem response) and assessment of communication abilities (expressive/receptive language, articulation, phonological awareness, and vocal affect recognition). Incidence of abnormal findings on at least one measure of audiological functioning was higher for the ASD group (55%) than controls (14.9%) or the general population estimate (6%). The presence of sound sensitivity was also considerably higher for the ASD group (37%) compared with controls (0%) or general population estimates (8–15%). When participants with ASD were dichotomized into groups with and without evidence of clinical audiological abnormality, no significant differences were identified on measures of communication; however, results of correlational analyses indicated that variability in hearing thresholds at middle range frequencies (2000 Hz) was significantly related to performance on all measures of speech articulation and language after correction for multiple comparisons (r?=??0.48 to r?=??0.53, P? 0.0045). These findings suggest that dichotomized classification of clinical audiology may not be sufficient to understand the role of subclinical hearing loss in ASD symptomatology and that treatment studies for mild/subclinical hearing loss in this population may be worthwhile. En ligne : http://dx.doi.org/10.1002/aur.1495 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282