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Commentary: The multifaceted nature of maternal depression as a risk factor for child psychopathology – reflections on Sellers et al. (2014) / Sherryl GOODMAN in Journal of Child Psychology and Psychiatry, 55-2 (February 2014)
[article]
Titre : Commentary: The multifaceted nature of maternal depression as a risk factor for child psychopathology – reflections on Sellers et al. (2014) Type de document : Texte imprimé et/ou numérique Auteurs : Sherryl GOODMAN, Auteur Article en page(s) : p.121-123 Langues : Anglais (eng) Mots-clés : Maternal depression risk mediators child psychopathology maternal antisocial behavior offspring depression Index. décimale : PER Périodiques Résumé : While much has been learned about depression in mothers as a risk for the development of psychopathology in offspring, many questions about how the risk is transmitted remain unanswered. Moreover, maternal depression is too often considered to be a unitary construct, ignoring the likely diversity among mothers with depression, which could play essential roles in understanding not only mechanisms of risk but also moderators of risk, i.e. for whom the association between maternal depression and adverse offspring outcomes may be stronger. Sellers et al. address both mechanisms and moderators, thereby contributing to the understanding of risk to offspring of depressed mothers in these two important ways. There is much to learn from this work, on many levels and for different audiences, including both researchers and practitioners. A key take-home message of this study for all readers is that understanding the role of maternal depression in associations with child psychopathology requires a nuanced view of the nature of risk to children from depression in mothers. The often co-occurring disorders and highly correlated additional aspects of the context in which depression occurs play important roles in the development of psychopathology in the offspring of depressed mothers. En ligne : http://dx.doi.org/10.1111/jcpp.12202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=220
in Journal of Child Psychology and Psychiatry > 55-2 (February 2014) . - p.121-123[article] Commentary: The multifaceted nature of maternal depression as a risk factor for child psychopathology – reflections on Sellers et al. (2014) [Texte imprimé et/ou numérique] / Sherryl GOODMAN, Auteur . - p.121-123.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-2 (February 2014) . - p.121-123
Mots-clés : Maternal depression risk mediators child psychopathology maternal antisocial behavior offspring depression Index. décimale : PER Périodiques Résumé : While much has been learned about depression in mothers as a risk for the development of psychopathology in offspring, many questions about how the risk is transmitted remain unanswered. Moreover, maternal depression is too often considered to be a unitary construct, ignoring the likely diversity among mothers with depression, which could play essential roles in understanding not only mechanisms of risk but also moderators of risk, i.e. for whom the association between maternal depression and adverse offspring outcomes may be stronger. Sellers et al. address both mechanisms and moderators, thereby contributing to the understanding of risk to offspring of depressed mothers in these two important ways. There is much to learn from this work, on many levels and for different audiences, including both researchers and practitioners. A key take-home message of this study for all readers is that understanding the role of maternal depression in associations with child psychopathology requires a nuanced view of the nature of risk to children from depression in mothers. The often co-occurring disorders and highly correlated additional aspects of the context in which depression occurs play important roles in the development of psychopathology in the offspring of depressed mothers. En ligne : http://dx.doi.org/10.1111/jcpp.12202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=220 Coping in context: The effects of long-term relations between interparental conflict and coping on the development of child psychopathology following parental divorce / K. L. O'HARA in Development and Psychopathology, 31-5 (December 2019)
[article]
Titre : Coping in context: The effects of long-term relations between interparental conflict and coping on the development of child psychopathology following parental divorce Type de document : Texte imprimé et/ou numérique Auteurs : K. L. O'HARA, Auteur ; Irwin N. SANDLER, Auteur ; S. A. WOLCHIK, Auteur ; J. Y. TEIN, Auteur Année de publication : 2019 Article en page(s) : p.1695-1713 Langues : Anglais (eng) Mots-clés : child psychopathology coping divorce interparental conflict prevention Index. décimale : PER Périodiques Résumé : Exposure to high levels of postdivorce interparental conflict is a well-documented risk factor for the development of psychopathology, and there is strong evidence of a subpopulation of families for which conflict persists for many years after divorce. However, existing studies have not elucidated differential trajectories of conflict within families over time, nor have they assessed the risk posed by conflict trajectories for development of psychopathology or evaluated potential protective effects of children's coping to mitigate such risk. We used growth mixture modeling to identify longitudinal trajectories of child-reported conflict over a period of six to eight years following divorce in a sample of 240 children. We related the trajectories to children's mental health problems, substance use, and risky sexual behaviors and assessed how children's coping prospectively predicted psychopathology in the different conflict trajectories. We identified three distinct trajectories of conflict; youth in two high-conflict trajectories showed deleterious effects on measures of psychopathology at baseline and the six-year follow-up. We found both main effects of coping and coping by conflict trajectory interaction effects in predicting problem outcomes at the six-year follow-up. The study supports the notion that improving youth's general capacity to cope adaptively is a potentially modifiable protective factor for all children facing parental divorce and that children in families with high levels of postdivorce conflict are a particularly appropriate group to target for coping-focused preventive interventions. En ligne : http://dx.doi.org/10.1017/s0954579419000981 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412
in Development and Psychopathology > 31-5 (December 2019) . - p.1695-1713[article] Coping in context: The effects of long-term relations between interparental conflict and coping on the development of child psychopathology following parental divorce [Texte imprimé et/ou numérique] / K. L. O'HARA, Auteur ; Irwin N. SANDLER, Auteur ; S. A. WOLCHIK, Auteur ; J. Y. TEIN, Auteur . - 2019 . - p.1695-1713.
Langues : Anglais (eng)
in Development and Psychopathology > 31-5 (December 2019) . - p.1695-1713
Mots-clés : child psychopathology coping divorce interparental conflict prevention Index. décimale : PER Périodiques Résumé : Exposure to high levels of postdivorce interparental conflict is a well-documented risk factor for the development of psychopathology, and there is strong evidence of a subpopulation of families for which conflict persists for many years after divorce. However, existing studies have not elucidated differential trajectories of conflict within families over time, nor have they assessed the risk posed by conflict trajectories for development of psychopathology or evaluated potential protective effects of children's coping to mitigate such risk. We used growth mixture modeling to identify longitudinal trajectories of child-reported conflict over a period of six to eight years following divorce in a sample of 240 children. We related the trajectories to children's mental health problems, substance use, and risky sexual behaviors and assessed how children's coping prospectively predicted psychopathology in the different conflict trajectories. We identified three distinct trajectories of conflict; youth in two high-conflict trajectories showed deleterious effects on measures of psychopathology at baseline and the six-year follow-up. We found both main effects of coping and coping by conflict trajectory interaction effects in predicting problem outcomes at the six-year follow-up. The study supports the notion that improving youth's general capacity to cope adaptively is a potentially modifiable protective factor for all children facing parental divorce and that children in families with high levels of postdivorce conflict are a particularly appropriate group to target for coping-focused preventive interventions. En ligne : http://dx.doi.org/10.1017/s0954579419000981 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412 Editorial: A double-edged sword: advantages and disadvantages to the current emphasis on biogenetic causes of child psychopathology / S. Alexandra BURT in Journal of Child Psychology and Psychiatry, 56-2 (February 2015)
[article]
Titre : Editorial: A double-edged sword: advantages and disadvantages to the current emphasis on biogenetic causes of child psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : S. Alexandra BURT, Auteur Article en page(s) : p.105-107 Langues : Anglais (eng) Mots-clés : Biogenetics biology–environment interplay child psychopathology main effects Index. décimale : PER Périodiques Résumé : Research on child psychopathology is a largely biogenetic endeavor these days, at least according to current funding priorities at the National Institutes of Health in the US. This heavy focus on genetic contributions to child psychopathology has some real advantages. Available research has conclusively indicated that child and adolescent mental health problems are partially genetic in origin and, moreover, are related to neural structure and function (as an example, see Plomin et al.). Moreover, these genetic effects may be responsible for some previously reported ‘environmental’ effects, such that, what appear to be direct environmental risk factors may in fact reflect genetic/familial risks. As one example, Sengupta et al. (this issue) found that maternal smoking during pregnancy was in fact a marker of maternal and paternal psychopathology. Put another way, the association between ADHD and maternal smoking during pregnancy may index a genetic/familial risk for a more severe form of ADHD, rather than a direct effect of uterine exposure to cigarettes. A final, more subtle reason for the current trend towards biogenetic research is that it has the rarely-discussed but all-too-important ‘allure of the unknown’. We have only just recently been able to directly explore the biological underpinnings of psychopathology; and as technology advances, so too will the insights gained (presumably). This offers both funding agencies and individual scientists the very real possibility of making a major new discovery – a siren's call for most of us. In sharp contrast, decades of research have explored putatively environmental contributions to child and adolescent psychopathology. New paradigm-shifting discoveries are thus likely to be fewer in number and farther between (if we continue using traditional study designs that omit joint consideration of biology, that is). In short, biogenetic research just feels more cutting edge at the moment. The clear merits of such work notwithstanding, there are a number of critical disadvantages to the current emphasis on genetics. These issues are presented below, not necessarily in order of importance. En ligne : http://dx.doi.org/10.1111/jcpp.12393 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259
in Journal of Child Psychology and Psychiatry > 56-2 (February 2015) . - p.105-107[article] Editorial: A double-edged sword: advantages and disadvantages to the current emphasis on biogenetic causes of child psychopathology [Texte imprimé et/ou numérique] / S. Alexandra BURT, Auteur . - p.105-107.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-2 (February 2015) . - p.105-107
Mots-clés : Biogenetics biology–environment interplay child psychopathology main effects Index. décimale : PER Périodiques Résumé : Research on child psychopathology is a largely biogenetic endeavor these days, at least according to current funding priorities at the National Institutes of Health in the US. This heavy focus on genetic contributions to child psychopathology has some real advantages. Available research has conclusively indicated that child and adolescent mental health problems are partially genetic in origin and, moreover, are related to neural structure and function (as an example, see Plomin et al.). Moreover, these genetic effects may be responsible for some previously reported ‘environmental’ effects, such that, what appear to be direct environmental risk factors may in fact reflect genetic/familial risks. As one example, Sengupta et al. (this issue) found that maternal smoking during pregnancy was in fact a marker of maternal and paternal psychopathology. Put another way, the association between ADHD and maternal smoking during pregnancy may index a genetic/familial risk for a more severe form of ADHD, rather than a direct effect of uterine exposure to cigarettes. A final, more subtle reason for the current trend towards biogenetic research is that it has the rarely-discussed but all-too-important ‘allure of the unknown’. We have only just recently been able to directly explore the biological underpinnings of psychopathology; and as technology advances, so too will the insights gained (presumably). This offers both funding agencies and individual scientists the very real possibility of making a major new discovery – a siren's call for most of us. In sharp contrast, decades of research have explored putatively environmental contributions to child and adolescent psychopathology. New paradigm-shifting discoveries are thus likely to be fewer in number and farther between (if we continue using traditional study designs that omit joint consideration of biology, that is). In short, biogenetic research just feels more cutting edge at the moment. The clear merits of such work notwithstanding, there are a number of critical disadvantages to the current emphasis on genetics. These issues are presented below, not necessarily in order of importance. En ligne : http://dx.doi.org/10.1111/jcpp.12393 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 Editorial: Translational genetics of child psychopathology: a distant dream? / Barbara MAUGHAN in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)
[article]
Titre : Editorial: Translational genetics of child psychopathology: a distant dream? Type de document : Texte imprimé et/ou numérique Auteurs : Barbara MAUGHAN, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur Article en page(s) : p.1065-1067 Langues : Anglais (eng) Mots-clés : Translational genetics child psychopathology heritability genetic variant markers psychiatric genetics Index. décimale : PER Périodiques Résumé : For decades now twin, family and adoption studies have pointed to a substantial role for genetic factors in risk for psychiatric disorder. Behaviour genetic studies are not, of course, designed to tell us about the ‘genetic architecture’ of disorders – the number of risk variants involved, their frequency, or their effects sizes – but their findings clearly suggest that given the high levels of heritability detected, identifying the gene variants involved could provide important pointers to aetiology, and might well have implications for treatment. In and of themselves heritability findings have little practical value as a basis for a translational genetics of psychiatric disorders. They cannot help us identify pathophysiological pathways that need to be targeted through therapeutic innovation or inform the sort of tailoring of treatments to individual biological ‘types’ to promote personalized medicine. To do these things we need to move from estimating heritability to identifying specific genetic markers implicating specific neuro-biological systems. En ligne : http://dx.doi.org/10.1111/jcpp.12323 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238
in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1065-1067[article] Editorial: Translational genetics of child psychopathology: a distant dream? [Texte imprimé et/ou numérique] / Barbara MAUGHAN, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur . - p.1065-1067.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1065-1067
Mots-clés : Translational genetics child psychopathology heritability genetic variant markers psychiatric genetics Index. décimale : PER Périodiques Résumé : For decades now twin, family and adoption studies have pointed to a substantial role for genetic factors in risk for psychiatric disorder. Behaviour genetic studies are not, of course, designed to tell us about the ‘genetic architecture’ of disorders – the number of risk variants involved, their frequency, or their effects sizes – but their findings clearly suggest that given the high levels of heritability detected, identifying the gene variants involved could provide important pointers to aetiology, and might well have implications for treatment. In and of themselves heritability findings have little practical value as a basis for a translational genetics of psychiatric disorders. They cannot help us identify pathophysiological pathways that need to be targeted through therapeutic innovation or inform the sort of tailoring of treatments to individual biological ‘types’ to promote personalized medicine. To do these things we need to move from estimating heritability to identifying specific genetic markers implicating specific neuro-biological systems. En ligne : http://dx.doi.org/10.1111/jcpp.12323 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 Maternal depression impacts child psychopathology across the first decade of life: Oxytocin and synchrony as markers of resilience / A. PRIEL in Journal of Child Psychology and Psychiatry, 60-1 (January 2019)
[article]
Titre : Maternal depression impacts child psychopathology across the first decade of life: Oxytocin and synchrony as markers of resilience Type de document : Texte imprimé et/ou numérique Auteurs : A. PRIEL, Auteur ; A. DJALOVSKI, Auteur ; O. ZAGOORY-SHARON, Auteur ; R. FELDMAN, Auteur Article en page(s) : p.30-42 Langues : Anglais (eng) Mots-clés : Maternal depression child psychopathology longitudinal studies oxytocin resilience synchrony Index. décimale : PER Périodiques Résumé : BACKGROUND: While maternal depression is known to carry long-term negative consequences for offspring, very few studies followed children longitudinally to address markers of resilience in the context of maternal depression. We focused on oxytocin (OT) and mother-child synchrony - the biological and behavioral arms of the neurobiology of affiliation - as correlates of resilience among children of depressed mothers. METHOD: A community birth-cohort was recruited on the second postbirth day and repeatedly assessed for maternal depression across the first year. At 6 and 10 years, mothers and children underwent psychiatric diagnosis, mother-child interactions were coded for maternal sensitivity, child social engagement, and mother-child synchrony, children's OT assayed, and externalizing and internalizing problems reported. RESULTS: Exposure to maternal depression markedly increased child propensity to develop Axis-I disorder at 6 and 10 years. Child OT showed main effects for both maternal depression and child psychiatric disorder at 6 and 10 years, with maternal or child psychopathology attenuating OT response. In contrast, maternal depression decreased synchrony at 6 years but by 10 years synchrony showed only child disorder effect, highlighting the shift from direct to indirect effects as children grow older. Path analysis linking maternal depression to child externalizing and internalizing problems at 10 years controlling for 6-year variables indicated that depression linked with decreased maternal sensitivity and child OT, which predicted reduced child engagement and synchrony, leading to higher externalizing and internalizing problems. OT and synchrony mediated the effects of maternal depression on child behavior problems and an alternative model without these resilience components provided less adequate fit. CONCLUSIONS: Maternal depression continues to play a role in children's development beyond infancy. The mediating effects of OT and synchronous, mutually regulated interactions underscore the role of plasticity in resilience. Results emphasize the need to follow children of depressed mothers across middle childhood and construct interventions that bolster age-appropriate synchrony. En ligne : http://dx.doi.org/10.1111/jcpp.12880 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=374
in Journal of Child Psychology and Psychiatry > 60-1 (January 2019) . - p.30-42[article] Maternal depression impacts child psychopathology across the first decade of life: Oxytocin and synchrony as markers of resilience [Texte imprimé et/ou numérique] / A. PRIEL, Auteur ; A. DJALOVSKI, Auteur ; O. ZAGOORY-SHARON, Auteur ; R. FELDMAN, Auteur . - p.30-42.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-1 (January 2019) . - p.30-42
Mots-clés : Maternal depression child psychopathology longitudinal studies oxytocin resilience synchrony Index. décimale : PER Périodiques Résumé : BACKGROUND: While maternal depression is known to carry long-term negative consequences for offspring, very few studies followed children longitudinally to address markers of resilience in the context of maternal depression. We focused on oxytocin (OT) and mother-child synchrony - the biological and behavioral arms of the neurobiology of affiliation - as correlates of resilience among children of depressed mothers. METHOD: A community birth-cohort was recruited on the second postbirth day and repeatedly assessed for maternal depression across the first year. At 6 and 10 years, mothers and children underwent psychiatric diagnosis, mother-child interactions were coded for maternal sensitivity, child social engagement, and mother-child synchrony, children's OT assayed, and externalizing and internalizing problems reported. RESULTS: Exposure to maternal depression markedly increased child propensity to develop Axis-I disorder at 6 and 10 years. Child OT showed main effects for both maternal depression and child psychiatric disorder at 6 and 10 years, with maternal or child psychopathology attenuating OT response. In contrast, maternal depression decreased synchrony at 6 years but by 10 years synchrony showed only child disorder effect, highlighting the shift from direct to indirect effects as children grow older. Path analysis linking maternal depression to child externalizing and internalizing problems at 10 years controlling for 6-year variables indicated that depression linked with decreased maternal sensitivity and child OT, which predicted reduced child engagement and synchrony, leading to higher externalizing and internalizing problems. OT and synchrony mediated the effects of maternal depression on child behavior problems and an alternative model without these resilience components provided less adequate fit. CONCLUSIONS: Maternal depression continues to play a role in children's development beyond infancy. The mediating effects of OT and synchronous, mutually regulated interactions underscore the role of plasticity in resilience. Results emphasize the need to follow children of depressed mothers across middle childhood and construct interventions that bolster age-appropriate synchrony. En ligne : http://dx.doi.org/10.1111/jcpp.12880 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=374 Research Review: Functional brain connectivity and child psychopathology – overview and methodological considerations for investigators new to the field / Marguerite MATTHEWS in Journal of Child Psychology and Psychiatry, 56-4 (April 2015)
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