12 recherche sur le mot-clé 'developmental'

Developmental functioning and medical Co-morbidity profile of children with complex and essential autism / Jaimie FLOR in Autism Research, 10-8 (August 2017)  

Public ISBD [article]  inAutism Research > 10-8 (August 2017) . - p.1344-1352 Titre : Developmental functioning and medical Co-morbidity profile of children with complex and essential autism Type de document : texte imprimé Auteurs : Jaimie FLOR, Auteur ; Jayne BELLANDO, Auteur ; Maya LOPEZ, Auteur ; Amy SHUI, Auteur Article en page(s) : p.1344-1352 Langues : Anglais (eng) Mots-clés : autism  developmental  children  microcephaly  dysmorphology  essential autism complex autism Index. décimale : PER Périodiques Résumé : Children with Autism Spectrum Disorders (ASD) may be characterized as “complex” (those with microcephaly and/or dysmorphology) or “essential” (those with neither of these two). Previous studies found subjects in the complex group exhibited lower IQ scores, poorer response to behavioral intervention, more seizures and more abnormal EEGs and brain MRIs compared to the essential group. The objective of this study was to determine if there are differences in complex versus essential subjects based on several developmental/psychological measures as well as certain medical comorbidities. This study utilized data from 1,347 individuals (2–17 years old) well-characterized subjects enrolled in Autism Treatment Network (ATN) Registry. Head circumference measurement and the Autism Dysmorphology Measure (ADM) were used by trained physicians to classify subjects as complex or essential. Significantly lower scores were seen for complex subjects in cognitive level, adaptive behavior and quality of life. Complex subjects showed significantly increased physician-documented GI symptoms and were on a higher number of medications. No significant differences in autism severity scores, behavioral ratings and parent-reported sleep problems were found. After adjusting for multiple comparisons made, adaptive scores remained significantly lower for the complex group, and the complex group used a significantly higher number of medications and had increased GI symptoms. Complex and essential autism subtypes may have distinct developmental and medical correlates and thus underlines the importance of looking for microcephaly and dysmorphology, when evaluating a child with autism. Determining this distinction in autism may have implications in prognosis, identifying medical co-morbidities, directing diagnostic evaluations and treatment interventions. En ligne : http://dx.doi.org/10.1002/aur.1779 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310 [article] Developmental functioning and medical Co-morbidity profile of children with complex and essential autism [texte imprimé] / Jaimie FLOR, Auteur ; Jayne BELLANDO, Auteur ; Maya LOPEZ, Auteur ; Amy SHUI, Auteur . - p.1344-1352. Langues : Anglais (eng) in Autism Research > 10-8 (August 2017) . - p.1344-1352 Mots-clés : autism  developmental  children  microcephaly  dysmorphology  essential autism complex autism Index. décimale : PER Périodiques Résumé : Children with Autism Spectrum Disorders (ASD) may be characterized as “complex” (those with microcephaly and/or dysmorphology) or “essential” (those with neither of these two). Previous studies found subjects in the complex group exhibited lower IQ scores, poorer response to behavioral intervention, more seizures and more abnormal EEGs and brain MRIs compared to the essential group. The objective of this study was to determine if there are differences in complex versus essential subjects based on several developmental/psychological measures as well as certain medical comorbidities. This study utilized data from 1,347 individuals (2–17 years old) well-characterized subjects enrolled in Autism Treatment Network (ATN) Registry. Head circumference measurement and the Autism Dysmorphology Measure (ADM) were used by trained physicians to classify subjects as complex or essential. Significantly lower scores were seen for complex subjects in cognitive level, adaptive behavior and quality of life. Complex subjects showed significantly increased physician-documented GI symptoms and were on a higher number of medications. No significant differences in autism severity scores, behavioral ratings and parent-reported sleep problems were found. After adjusting for multiple comparisons made, adaptive scores remained significantly lower for the complex group, and the complex group used a significantly higher number of medications and had increased GI symptoms. Complex and essential autism subtypes may have distinct developmental and medical correlates and thus underlines the importance of looking for microcephaly and dysmorphology, when evaluating a child with autism. Determining this distinction in autism may have implications in prognosis, identifying medical co-morbidities, directing diagnostic evaluations and treatment interventions. En ligne : http://dx.doi.org/10.1002/aur.1779 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310

Complex, low-intensity, individualised naturalistic developmental behavioural intervention in toddlers and pre-schoolers with autism spectrum disorder: The multicentre, observer-blind, parallel-group randomised-controlled A-FFIP trial / Christine M. FREITAG in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1500-1513 Titre : Complex, low-intensity, individualised naturalistic developmental behavioural intervention in toddlers and pre-schoolers with autism spectrum disorder: The multicentre, observer-blind, parallel-group randomised-controlled A-FFIP trial Type de document : texte imprimé Auteurs : Christine M. FREITAG, Auteur ; Marietta KIRCHNER, Auteur ; Lukas D. SAUER, Auteur ; Solvejg K. KLEBER, Auteur ; Leonie POLZER, Auteur ; Naisan RAJI, Auteur ; Christian LEMLER, Auteur ; Ulrike FRÖHLICH, Auteur ; Tomasz A. JARCZOK, Auteur ; Julia GEIßLER, Auteur ; Franziska RADTKE, Auteur ; Melanie RING, Auteur ; Veit ROESSNER, Auteur ; Regina TAURINES, Auteur ; Michelle NOTERDAEME, Auteur ; Karoline TEUFEL, Auteur ; Ziyon KIM, Auteur ; Janina KITZEROW-CLEVEN, Auteur Article en page(s) : p.1500-1513 Langues : Anglais (eng) Mots-clés : Naturalistic  developmental  behavioural  autism  social communication  repetitive behaviour  randomised-controlled Index. décimale : PER Périodiques Résumé : Background Naturalistic developmental behavioural interventions (NDBI) may improve social communication in toddlers/pre-school aged children with autism spectrum disorder (ASD). Here, we study efficacy of the low-intensity, complex NDBI ?Frankfurt Early Intervention Program for ASD? (A-FFIP) over 1 year by a confirmatory phase-III, prospective, randomised, controlled, parallel-group study with two treatment arms over four centres. Methods Main inclusion criteria: ASD (DSM-5), age 24 66 months, developmental quotient >30. Intervention: Manualised A-FFIP intervention. Control intervention: Early intervention as usual (EIAU). Primary outcome: Change in core ASD symptoms from baseline (T2) to immediate intervention endpoint at 12 months (T6) based on the blindly rated Brief Observation for Communication Change (BOSCC) total score. Statistical analysis: Mixed model for repeated measures with covariates baseline BOSCC-total, chronological age and centre. Results Between July 2018 and October 2021, N 134 children with ASD were randomly allocated to intervention (A-FFIP: n 68, EIAU: n 66). Groups did not differ at baseline, with a mean age of 49 (SD 10) months, a mean developmental age of 23.3 (SD 13.6) months and 26 (19.4%) females. The SARS-CoV-2 pandemic interfered severely with trial procedures. Intention-to-treat analysis in the primary analysis set, with at least one postbaseline BOSCC measure (A-FFIP n 64, EIAU n 60), did not find differences in the primary outcome by group (adjusted ES 0.06, 95% CI to 0.24 to 0.11). SARS-CoV2-related lockdown led to less improvement across groups. Secondary outcomes showed stronger improvements in parent-rated repetitive behaviour as well as parent- and teacher-rated executive functions for A-FFIP versus EIAU. Adverse events were comparable between groups. Conclusions The manualised NDBI program A-FFIP, which allows individually targeting six core basic abilities and five developmental domains related to longitudinal development in ASD, did not improve social communication, cognitive or behavioural outcomes beyond EIAU after 1 year, but may improve repetitive behaviour and executive function. En ligne : https://doi.org/10.1111/jcpp.14162 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Complex, low-intensity, individualised naturalistic developmental behavioural intervention in toddlers and pre-schoolers with autism spectrum disorder: The multicentre, observer-blind, parallel-group randomised-controlled A-FFIP trial [texte imprimé] / Christine M. FREITAG, Auteur ; Marietta KIRCHNER, Auteur ; Lukas D. SAUER, Auteur ; Solvejg K. KLEBER, Auteur ; Leonie POLZER, Auteur ; Naisan RAJI, Auteur ; Christian LEMLER, Auteur ; Ulrike FRÖHLICH, Auteur ; Tomasz A. JARCZOK, Auteur ; Julia GEIßLER, Auteur ; Franziska RADTKE, Auteur ; Melanie RING, Auteur ; Veit ROESSNER, Auteur ; Regina TAURINES, Auteur ; Michelle NOTERDAEME, Auteur ; Karoline TEUFEL, Auteur ; Ziyon KIM, Auteur ; Janina KITZEROW-CLEVEN, Auteur . - p.1500-1513. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1500-1513 Mots-clés : Naturalistic  developmental  behavioural  autism  social communication  repetitive behaviour  randomised-controlled Index. décimale : PER Périodiques Résumé : Background Naturalistic developmental behavioural interventions (NDBI) may improve social communication in toddlers/pre-school aged children with autism spectrum disorder (ASD). Here, we study efficacy of the low-intensity, complex NDBI ?Frankfurt Early Intervention Program for ASD? (A-FFIP) over 1 year by a confirmatory phase-III, prospective, randomised, controlled, parallel-group study with two treatment arms over four centres. Methods Main inclusion criteria: ASD (DSM-5), age 24 66 months, developmental quotient >30. Intervention: Manualised A-FFIP intervention. Control intervention: Early intervention as usual (EIAU). Primary outcome: Change in core ASD symptoms from baseline (T2) to immediate intervention endpoint at 12 months (T6) based on the blindly rated Brief Observation for Communication Change (BOSCC) total score. Statistical analysis: Mixed model for repeated measures with covariates baseline BOSCC-total, chronological age and centre. Results Between July 2018 and October 2021, N 134 children with ASD were randomly allocated to intervention (A-FFIP: n 68, EIAU: n 66). Groups did not differ at baseline, with a mean age of 49 (SD 10) months, a mean developmental age of 23.3 (SD 13.6) months and 26 (19.4%) females. The SARS-CoV-2 pandemic interfered severely with trial procedures. Intention-to-treat analysis in the primary analysis set, with at least one postbaseline BOSCC measure (A-FFIP n 64, EIAU n 60), did not find differences in the primary outcome by group (adjusted ES 0.06, 95% CI to 0.24 to 0.11). SARS-CoV2-related lockdown led to less improvement across groups. Secondary outcomes showed stronger improvements in parent-rated repetitive behaviour as well as parent- and teacher-rated executive functions for A-FFIP versus EIAU. Adverse events were comparable between groups. Conclusions The manualised NDBI program A-FFIP, which allows individually targeting six core basic abilities and five developmental domains related to longitudinal development in ASD, did not improve social communication, cognitive or behavioural outcomes beyond EIAU after 1 year, but may improve repetitive behaviour and executive function. En ligne : https://doi.org/10.1111/jcpp.14162 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Information Processing Deficits Associated with Developmental Coordination Disorder: A Meta-analysis of Research Findings / Peter H. WILSON in Journal of Child Psychology and Psychiatry, 39-6 (September 1998)

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 39-6 (September 1998) . - p.829-840 Titre : Information Processing Deficits Associated with Developmental Coordination Disorder: A Meta-analysis of Research Findings Type de document : texte imprimé Auteurs : Peter H. WILSON, Auteur ; Beryl E. MCKENZIE, Auteur Année de publication : 1998 Article en page(s) : p.829-840 Langues : Anglais (eng) Mots-clés : Clumsy children  information processing  perception  meta-analysis  Developmental  Coordination Disorder Index. décimale : PER Périodiques Résumé : A meta-analysis was conducted to identify information processing factors that characterise children with Developmental Coordination Disorder (DCD). A total of 50 studies yielded 374 effect sizes based on 983 DCD and 987 control children. A mild generalised performance deficit was indicated, since motor-impaired children were inferior on almost all measures of information processing. There were, however, several areas where their deficiencies were more pronounced. The greatest deficiency was in visual-spatial processing. This was evident regardless of whether or not the tasks involved a motor component. Most other deficiencies were in the small-to-moderate range and included kinaesthetic and cross-modal processing. The findings support the notion that perceptual problems, particularly in the visual modality, are associated with difficulties in motor coordination. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=123 [article] Information Processing Deficits Associated with Developmental Coordination Disorder: A Meta-analysis of Research Findings [texte imprimé] / Peter H. WILSON, Auteur ; Beryl E. MCKENZIE, Auteur . - 1998 . - p.829-840. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 39-6 (September 1998) . - p.829-840 Mots-clés : Clumsy children  information processing  perception  meta-analysis  Developmental  Coordination Disorder Index. décimale : PER Périodiques Résumé : A meta-analysis was conducted to identify information processing factors that characterise children with Developmental Coordination Disorder (DCD). A total of 50 studies yielded 374 effect sizes based on 983 DCD and 987 control children. A mild generalised performance deficit was indicated, since motor-impaired children were inferior on almost all measures of information processing. There were, however, several areas where their deficiencies were more pronounced. The greatest deficiency was in visual-spatial processing. This was evident regardless of whether or not the tasks involved a motor component. Most other deficiencies were in the small-to-moderate range and included kinaesthetic and cross-modal processing. The findings support the notion that perceptual problems, particularly in the visual modality, are associated with difficulties in motor coordination. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=123

Naturalistic Developmental Behavioral Interventions: Empirically Validated Treatments for Autism Spectrum Disorder / Laura SCHREIBMAN in Journal of Autism and Developmental Disorders, 45-8 (August 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2411-2428 Titre : Naturalistic Developmental Behavioral Interventions: Empirically Validated Treatments for Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Laura SCHREIBMAN, Auteur ; Geraldine DAWSON, Auteur ; Aubyn C. STAHMER, Auteur ; Rebecca LANDA, Auteur ; Sally J. ROGERS, Auteur ; Gail G. MCGEE, Auteur ; Connie KASARI, Auteur ; Brooke R. INGERSOLL, Auteur ; Ann P. KAISER, Auteur ; Yvonne BRUINSMA, Auteur ; Erin K. MCNERNEY, Auteur ; Amy M. WETHERBY, Auteur ; Alycia K. HALLADAY, Auteur Année de publication : 2015 Article en page(s) : p.2411-2428 Langues : Anglais (eng) Mots-clés : Early intervention  Naturalistic  Developmental  Behavioral Index. décimale : PER Périodiques Résumé : Earlier autism diagnosis, the importance of early intervention, and development of specific interventions for young children have contributed to the emergence of similar, empirically supported, autism interventions that represent the merging of applied behavioral and developmental sciences. “Naturalistic Developmental Behavioral Interventions (NDBI)” are implemented in natural settings, involve shared control between child and therapist, utilize natural contingencies, and use a variety of behavioral strategies to teach developmentally appropriate and prerequisite skills. We describe the development of NDBIs, their theoretical bases, empirical support, requisite characteristics, common features, and suggest future research needs. We wish to bring parsimony to a field that includes interventions with different names but common features thus improving understanding and choice-making among families, service providers and referring agencies. En ligne : http://dx.doi.org/10.1007/s10803-015-2407-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263 [article] Naturalistic Developmental Behavioral Interventions: Empirically Validated Treatments for Autism Spectrum Disorder [texte imprimé] / Laura SCHREIBMAN, Auteur ; Geraldine DAWSON, Auteur ; Aubyn C. STAHMER, Auteur ; Rebecca LANDA, Auteur ; Sally J. ROGERS, Auteur ; Gail G. MCGEE, Auteur ; Connie KASARI, Auteur ; Brooke R. INGERSOLL, Auteur ; Ann P. KAISER, Auteur ; Yvonne BRUINSMA, Auteur ; Erin K. MCNERNEY, Auteur ; Amy M. WETHERBY, Auteur ; Alycia K. HALLADAY, Auteur . - 2015 . - p.2411-2428. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2411-2428 Mots-clés : Early intervention  Naturalistic  Developmental  Behavioral Index. décimale : PER Périodiques Résumé : Earlier autism diagnosis, the importance of early intervention, and development of specific interventions for young children have contributed to the emergence of similar, empirically supported, autism interventions that represent the merging of applied behavioral and developmental sciences. “Naturalistic Developmental Behavioral Interventions (NDBI)” are implemented in natural settings, involve shared control between child and therapist, utilize natural contingencies, and use a variety of behavioral strategies to teach developmentally appropriate and prerequisite skills. We describe the development of NDBIs, their theoretical bases, empirical support, requisite characteristics, common features, and suggest future research needs. We wish to bring parsimony to a field that includes interventions with different names but common features thus improving understanding and choice-making among families, service providers and referring agencies. En ligne : http://dx.doi.org/10.1007/s10803-015-2407-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263

Specialized Inpatient Psychiatry Units for Children with Autism and Developmental Disorders: A United States Survey / Matthew SIEGEL in Journal of Autism and Developmental Disorders, 42-9 (September 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1863-1869 Titre : Specialized Inpatient Psychiatry Units for Children with Autism and Developmental Disorders: A United States Survey Type de document : texte imprimé Auteurs : Matthew SIEGEL, Auteur ; Kathleen DOYLE, Auteur ; Bruce CHEMELSKI, Auteur ; David PAYNE, Auteur ; BETH ELLSWORTH, Auteur ; Jamie HARMON, Auteur ; Douglas ROBBINS, Auteur ; Briana MILLIGAN, Auteur ; Martin LUBETSKY, Auteur Année de publication : 2012 Article en page(s) : p.1863-1869 Langues : Anglais (eng) Mots-clés : Autism  Inpatient  Developmental  Admission Index. décimale : PER Périodiques Résumé : A cross sectional survey was performed to obtain the characteristics of specialized inpatient psychiatry units exclusively serving children with autism and other developmental disorders in the United States. Identified units were surveyed on basic demographic characteristics, clinical challenges and therapeutic modalities. Average length of stay was 42.3 days, children with autism spectrum disorders constituted the majority of the inpatient population (62.5–87.5%), and obtaining adequate post-discharge services was identified as the greatest challenge. Health policy implications and future research directions are suggested. En ligne : http://dx.doi.org/10.1007/s10803-011-1426-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 [article] Specialized Inpatient Psychiatry Units for Children with Autism and Developmental Disorders: A United States Survey [texte imprimé] / Matthew SIEGEL, Auteur ; Kathleen DOYLE, Auteur ; Bruce CHEMELSKI, Auteur ; David PAYNE, Auteur ; BETH ELLSWORTH, Auteur ; Jamie HARMON, Auteur ; Douglas ROBBINS, Auteur ; Briana MILLIGAN, Auteur ; Martin LUBETSKY, Auteur . - 2012 . - p.1863-1869. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1863-1869 Mots-clés : Autism  Inpatient  Developmental  Admission Index. décimale : PER Périodiques Résumé : A cross sectional survey was performed to obtain the characteristics of specialized inpatient psychiatry units exclusively serving children with autism and other developmental disorders in the United States. Identified units were surveyed on basic demographic characteristics, clinical challenges and therapeutic modalities. Average length of stay was 42.3 days, children with autism spectrum disorders constituted the majority of the inpatient population (62.5–87.5%), and obtaining adequate post-discharge services was identified as the greatest challenge. Health policy implications and future research directions are suggested. En ligne : http://dx.doi.org/10.1007/s10803-011-1426-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180

Autism risk genes are evolutionarily ancient and maintain a unique feature landscape that echoes their function / Emily L. CASANOVA in Autism Research, 12-6 (June 2019)  

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Autism spectrum disorders: An historical synthesis and a multidimensional assessment toward a tailored therapeutic program / Jean XAVIER in Research in Autism Spectrum Disorders, 18 (October 2015)  

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Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells / Jesse BARNES in Molecular Autism, 9 (2018)  

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Visual search strategies during facial recognition in children with ASD / Matthew A. ALBRECHT in Research in Autism Spectrum Disorders, 8-5 (May 2014)  

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Association of Rigid-Compulsive Behavior with Functional Constipation in Autism Spectrum Disorder / Sarah MARLER in Journal of Autism and Developmental Disorders, 47-6 (June 2017)  

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