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Faire une suggestionAnnual Research Review: Neural mechanisms of eating disorders in youth – from current theory and findings to future directions / Kelsey HAGAN in Journal of Child Psychology and Psychiatry, 67-4 (April 2026)
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Titre : Annual Research Review: Neural mechanisms of eating disorders in youth – from current theory and findings to future directions Type de document : texte imprimé Auteurs : Kelsey HAGAN, Auteur ; E. Caitlin LLOYD, Auteur ; Sasha GORRELL, Auteur Année de publication : 2026 Article en page(s) : p.444-466 Langues : Anglais (eng) Mots-clés : Eating disorders anorexia nervosa bulimia nervosa binge-eating disorder avoidant/restrictive food intake disorder neurobiology adolescent eating disorders Index. décimale : PER Périodiques Résumé : Eating disorders are prevalent and profoundly debilitating psychiatric conditions with multifactorial etiology that frequently manifest during adolescence. This developmental stage is characterized by significant neurostructural and neurofunctional change, which may create a context conducive to the emergence of eating pathology. In this Annual Research Review, we examine notable changes in brain structure and function that occur during adolescence and elucidate theoretical models that connect neural modifications to eating disorders. Subsequently, we present a narrative review and critical analysis of the extant research on the neural correlates of eating disorders in adolescents and young adults (up to age 24). We conclude by pinpointing gaps in the literature and highlighting avenues for future inquiries into the neural correlates of eating disorders in youth. Overall, this Annual Research Review emphasizes the scarcity of research focused on the neural correlates of eating disorders in young persons and its predominant emphasis on anorexia nervosa in comparison to other eating disorders thus far. Future neurobiological investigations in adolescent eating disorders hold the promise of advancing our knowledge of these complex conditions and improving therapeutic outcomes through the development of mechanistic interventions. En ligne : https://doi.org/10.1111/jcpp.70029 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=584
in Journal of Child Psychology and Psychiatry > 67-4 (April 2026) . - p.444-466[article] Annual Research Review: Neural mechanisms of eating disorders in youth – from current theory and findings to future directions [texte imprimé] / Kelsey HAGAN, Auteur ; E. Caitlin LLOYD, Auteur ; Sasha GORRELL, Auteur . - 2026 . - p.444-466.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 67-4 (April 2026) . - p.444-466
Mots-clés : Eating disorders anorexia nervosa bulimia nervosa binge-eating disorder avoidant/restrictive food intake disorder neurobiology adolescent eating disorders Index. décimale : PER Périodiques Résumé : Eating disorders are prevalent and profoundly debilitating psychiatric conditions with multifactorial etiology that frequently manifest during adolescence. This developmental stage is characterized by significant neurostructural and neurofunctional change, which may create a context conducive to the emergence of eating pathology. In this Annual Research Review, we examine notable changes in brain structure and function that occur during adolescence and elucidate theoretical models that connect neural modifications to eating disorders. Subsequently, we present a narrative review and critical analysis of the extant research on the neural correlates of eating disorders in adolescents and young adults (up to age 24). We conclude by pinpointing gaps in the literature and highlighting avenues for future inquiries into the neural correlates of eating disorders in youth. Overall, this Annual Research Review emphasizes the scarcity of research focused on the neural correlates of eating disorders in young persons and its predominant emphasis on anorexia nervosa in comparison to other eating disorders thus far. Future neurobiological investigations in adolescent eating disorders hold the promise of advancing our knowledge of these complex conditions and improving therapeutic outcomes through the development of mechanistic interventions. En ligne : https://doi.org/10.1111/jcpp.70029 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=584 Childhood psychopathology in children of women with eating disorders: understanding risk mechanisms / Nadia MICALI in Journal of Child Psychology and Psychiatry, 55-2 (February 2014)
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Titre : Childhood psychopathology in children of women with eating disorders: understanding risk mechanisms Type de document : texte imprimé Auteurs : Nadia MICALI, Auteur ; Daniel STAHL, Auteur ; Janet TREASURE, Auteur ; Emily SIMONOFF, Auteur Article en page(s) : p.124-134 Langues : Anglais (eng) Mots-clés : ALSPAC child psychopathology eating disorders parental mental health risk mechanisms Index. décimale : PER Périodiques Résumé : Background Very few studies have investigated psychopathology in children of mothers with eating disorders (ED). We aimed to determine the effect of maternal ED on childhood psychopathology in a large population-based cohort and investigate relevant risk pathways using structural equation modeling (SEM). Methods Data on emotional and behavioral problems at 3½ years were obtained prospectively on 8,622 children from the Avon Longitudinal Study of Parents and Children (ALSPAC). Children of exposed women who self-reported lifetime anorexia nervosa (AN, N = 193) or bulimia nervosa (BN, N = 158) in pregnancy were compared with children of unexposed women (N = 8,271) using linear and logistic regression models. SEM was used to determine best-fitting risk models by child gender. Results There was evidence that girls of AN women were more likely to have emotional, conduct, and hyperactivity disorders [Odds Ratio (OR): 1.7 (95% Confidence Intervals 1.0–3.0); OR: 2.2 (1.2–4.0); OR: 1.8 (1.1–3.1), respectively] and boys of AN women to have emotional disorders compared with unexposed [OR: 2.0(1.2–3.4)]. Girls of women with BN were more likely to show hyperactivity [OR: 1.7 (1.0–3.1)]; and boys to show emotional and conduct disorders compared with unexposed [OR: 2.2 (1.2–3.9); OR: 2.4 (1.4–4.2), respectively]. SEM models showed that pregnancy anxiety and depression mediated the effect of maternal ED on child psychopathology. Conclusions Maternal ED are associated with different childhood psychopathology outcomes in boys and girls. Pregnancy anxiety and depression and active ED symptoms are important mediators of risk and are preventable; the direct effect of maternal lifetime ED was small. En ligne : http://dx.doi.org/10.1111/jcpp.12112 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221
in Journal of Child Psychology and Psychiatry > 55-2 (February 2014) . - p.124-134[article] Childhood psychopathology in children of women with eating disorders: understanding risk mechanisms [texte imprimé] / Nadia MICALI, Auteur ; Daniel STAHL, Auteur ; Janet TREASURE, Auteur ; Emily SIMONOFF, Auteur . - p.124-134.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-2 (February 2014) . - p.124-134
Mots-clés : ALSPAC child psychopathology eating disorders parental mental health risk mechanisms Index. décimale : PER Périodiques Résumé : Background Very few studies have investigated psychopathology in children of mothers with eating disorders (ED). We aimed to determine the effect of maternal ED on childhood psychopathology in a large population-based cohort and investigate relevant risk pathways using structural equation modeling (SEM). Methods Data on emotional and behavioral problems at 3½ years were obtained prospectively on 8,622 children from the Avon Longitudinal Study of Parents and Children (ALSPAC). Children of exposed women who self-reported lifetime anorexia nervosa (AN, N = 193) or bulimia nervosa (BN, N = 158) in pregnancy were compared with children of unexposed women (N = 8,271) using linear and logistic regression models. SEM was used to determine best-fitting risk models by child gender. Results There was evidence that girls of AN women were more likely to have emotional, conduct, and hyperactivity disorders [Odds Ratio (OR): 1.7 (95% Confidence Intervals 1.0–3.0); OR: 2.2 (1.2–4.0); OR: 1.8 (1.1–3.1), respectively] and boys of AN women to have emotional disorders compared with unexposed [OR: 2.0(1.2–3.4)]. Girls of women with BN were more likely to show hyperactivity [OR: 1.7 (1.0–3.1)]; and boys to show emotional and conduct disorders compared with unexposed [OR: 2.2 (1.2–3.9); OR: 2.4 (1.4–4.2), respectively]. SEM models showed that pregnancy anxiety and depression mediated the effect of maternal ED on child psychopathology. Conclusions Maternal ED are associated with different childhood psychopathology outcomes in boys and girls. Pregnancy anxiety and depression and active ED symptoms are important mediators of risk and are preventable; the direct effect of maternal lifetime ED was small. En ligne : http://dx.doi.org/10.1111/jcpp.12112 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 "For Me, the Anorexia is Just a Symptom, and the Cause is the Autism": Investigating Restrictive Eating Disorders in Autistic Women / Janina BREDE in Journal of Autism and Developmental Disorders, 50-12 (December 2020)
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Titre : "For Me, the Anorexia is Just a Symptom, and the Cause is the Autism": Investigating Restrictive Eating Disorders in Autistic Women Type de document : texte imprimé Auteurs : Janina BREDE, Auteur ; Charli BABB, Auteur ; Catherine R.G. JONES, Auteur ; Mair ELLIOTT, Auteur ; Cathy ZANKER, Auteur ; Kate TCHANTURIA, Auteur ; Lucy SERPELL, Auteur ; John FOX, Auteur ; William MANDY, Auteur Article en page(s) : p.4280-4296 Langues : Anglais (eng) Mots-clés : Anorexia nervosa Autism Co-occurrence Eating disorders Females Qualitative research Index. décimale : PER Périodiques Résumé : Autistic women are overrepresented among people in treatment for Anorexia Nervosa (AN). The current study aimed to: (1) better understand how AN develops and persists in autistic individuals from the perspective of autistic women, parents and healthcare professionals; (2) derive a theoretical model of restrictive eating difficulties in autism. We conducted 44 semi-structured interviews and used Thematic Analysis to identify patterns of meaning across the data. Themes related to sensory sensitivities, social interaction and relationships, sense of self and identity, difficulties with emotions, thinking styles, and a need for control and predictability. We developed a model of potential autism-specific mechanisms underlying restrictive eating difficulties. This study generated novel insights, which have the potential to inform treatment adaptations following empirical testing. En ligne : http://dx.doi.org/10.1007/s10803-020-04479-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Autism and Developmental Disorders > 50-12 (December 2020) . - p.4280-4296[article] "For Me, the Anorexia is Just a Symptom, and the Cause is the Autism": Investigating Restrictive Eating Disorders in Autistic Women [texte imprimé] / Janina BREDE, Auteur ; Charli BABB, Auteur ; Catherine R.G. JONES, Auteur ; Mair ELLIOTT, Auteur ; Cathy ZANKER, Auteur ; Kate TCHANTURIA, Auteur ; Lucy SERPELL, Auteur ; John FOX, Auteur ; William MANDY, Auteur . - p.4280-4296.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 50-12 (December 2020) . - p.4280-4296
Mots-clés : Anorexia nervosa Autism Co-occurrence Eating disorders Females Qualitative research Index. décimale : PER Périodiques Résumé : Autistic women are overrepresented among people in treatment for Anorexia Nervosa (AN). The current study aimed to: (1) better understand how AN develops and persists in autistic individuals from the perspective of autistic women, parents and healthcare professionals; (2) derive a theoretical model of restrictive eating difficulties in autism. We conducted 44 semi-structured interviews and used Thematic Analysis to identify patterns of meaning across the data. Themes related to sensory sensitivities, social interaction and relationships, sense of self and identity, difficulties with emotions, thinking styles, and a need for control and predictability. We developed a model of potential autism-specific mechanisms underlying restrictive eating difficulties. This study generated novel insights, which have the potential to inform treatment adaptations following empirical testing. En ligne : http://dx.doi.org/10.1007/s10803-020-04479-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Maternal eating disorders and infant feeding difficulties: maternal and child mediators in a longitudinal general population study / Nadia MICALI in Journal of Child Psychology and Psychiatry, 52-7 (July 2011)
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Titre : Maternal eating disorders and infant feeding difficulties: maternal and child mediators in a longitudinal general population study Type de document : texte imprimé Auteurs : Nadia MICALI, Auteur ; Emily SIMONOFF, Auteur ; Daniel STAHL, Auteur ; Janet TREASURE, Auteur Année de publication : 2011 Article en page(s) : p.800-807 Langues : Anglais (eng) Mots-clés : ALSPAC eating disorders feeding anxiety depression;infants Index. décimale : PER Périodiques Résumé : Background: Maternal eating disorders (ED) have been shown to increase the risk of feeding difficulties in the offspring. Very few studies, however, have investigated whether the effect of a maternal ED on childhood feeding is a direct effect or whether it can be ascribed to other child or maternal factors. We aimed to determine the role of maternal anxiety and depression in mediating the risk for feeding difficulties in infants of women with ED.
Methods: A prospective study comparing women with lifetime ED (441) and without any lifetime psychiatric disorder (10,461) and their infants from the Avon Longitudinal Study of Parents and Children (ALSPAC). We investigated the effect of: maternal anxiety and depression in late pregnancy (32 weeks) and the post-partum (8 weeks), child temperament and developmental status on infant feeding difficulties at 1 and 6 months. We also investigated the effect of active pregnancy ED symptoms. We tested 3 models and their fit to the data using structured equation modelling: a direct effect model, a fully mediational model and an integrated (partial meditational) model.
Results: The integrated model including a direct effect of maternal lifetime ED on infant feeding and a mediational path via maternal distress (a latent variable combining anxiety and depression) fitted the data best. This also applied to maternal pregnancy ED symptoms. Feeding difficulties in turn increased maternal distress over time.
Conclusions: Lifetime ED and active pregnancy ED increase the risk for infant feeding difficulties and do so via maternal distress (i.e., depression and anxiety). This has important implications for prevention and early intervention in relation to infant feeding difficulties, as well as for future research in the field.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02341.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=126
in Journal of Child Psychology and Psychiatry > 52-7 (July 2011) . - p.800-807[article] Maternal eating disorders and infant feeding difficulties: maternal and child mediators in a longitudinal general population study [texte imprimé] / Nadia MICALI, Auteur ; Emily SIMONOFF, Auteur ; Daniel STAHL, Auteur ; Janet TREASURE, Auteur . - 2011 . - p.800-807.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 52-7 (July 2011) . - p.800-807
Mots-clés : ALSPAC eating disorders feeding anxiety depression;infants Index. décimale : PER Périodiques Résumé : Background: Maternal eating disorders (ED) have been shown to increase the risk of feeding difficulties in the offspring. Very few studies, however, have investigated whether the effect of a maternal ED on childhood feeding is a direct effect or whether it can be ascribed to other child or maternal factors. We aimed to determine the role of maternal anxiety and depression in mediating the risk for feeding difficulties in infants of women with ED.
Methods: A prospective study comparing women with lifetime ED (441) and without any lifetime psychiatric disorder (10,461) and their infants from the Avon Longitudinal Study of Parents and Children (ALSPAC). We investigated the effect of: maternal anxiety and depression in late pregnancy (32 weeks) and the post-partum (8 weeks), child temperament and developmental status on infant feeding difficulties at 1 and 6 months. We also investigated the effect of active pregnancy ED symptoms. We tested 3 models and their fit to the data using structured equation modelling: a direct effect model, a fully mediational model and an integrated (partial meditational) model.
Results: The integrated model including a direct effect of maternal lifetime ED on infant feeding and a mediational path via maternal distress (a latent variable combining anxiety and depression) fitted the data best. This also applied to maternal pregnancy ED symptoms. Feeding difficulties in turn increased maternal distress over time.
Conclusions: Lifetime ED and active pregnancy ED increase the risk for infant feeding difficulties and do so via maternal distress (i.e., depression and anxiety). This has important implications for prevention and early intervention in relation to infant feeding difficulties, as well as for future research in the field.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02341.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=126 Neurobehavioural and cognitive development in infants born to mothers with eating disorders / Manuela BARONA in Journal of Child Psychology and Psychiatry, 58-8 (August 2017)
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Titre : Neurobehavioural and cognitive development in infants born to mothers with eating disorders Type de document : texte imprimé Auteurs : Manuela BARONA, Auteur ; Emma TABORELLI, Auteur ; Freya CORFIELD, Auteur ; Susan PAWLBY, Auteur ; Abigail EASTER, Auteur ; Ulrike SCHMIDT, Auteur ; Janet TREASURE, Auteur ; Nadia MICALI, Auteur Article en page(s) : p.931-938 Langues : Anglais (eng) Mots-clés : Brazelton Neonatal Behavioural Assessment Scale Bayley Scales of Infant and Toddler Development eating disorders child development Index. décimale : PER Périodiques Résumé : Introduction Although recent research has focused on the effects of maternal eating disorders (EDs) on children, little is known about the effect of maternal EDs on neurobiological outcomes in newborns and infants. This study is the first to investigate neurobehavioural regulation and cognitive development in newborns and infants of mothers with EDs. Methods Women with an active and past ED and healthy controls were recruited to a prospective longitudinal study during their first trimester or second trimester of pregnancy. Newborns and infants of mothers with ED were compared with newborns and infants of healthy controls on (a) neurobehavioural dysregulation using the Brazelton Neonatal Behavioural Assessment Scale at 8 days postpartum (active ED, n = 15; past ED, n = 20; healthy controls, n = 28); and (b) cognitive development using the Bayley Scales of Infant and Toddler Development at 1-year postpartum (active ED, n = 18; past ED, n = 19; healthy controls, n = 28). In order to maintain the largest possible sample at each time point, sample size varied across time points. Results Newborns of mothers with an active ED had worse autonomic stability when compared with newborns of healthy controls [B = −0.34 (−1.81, −0.26)]. Infants of mothers with a past ED had poorer language [B = −0.33 (−13.6, −1.9)] and motor development [B = −0.32 (−18.4, −1.3)] compared with healthy controls. Conclusions Children of mothers with ED display neurobehavioural dysregulation early after birth and poorer language and motor development at 1 year. These characteristics suggest evidence of early neurobiological markers in children at risk. Differential outcomes in children of women with active versus past ED suggest that active symptomatology during pregnancy might have an effect on physiological reactivity while cognitive characteristics might be more stable markers of risk for ED. En ligne : http://dx.doi.org/10.1111/jcpp.12736 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=316
in Journal of Child Psychology and Psychiatry > 58-8 (August 2017) . - p.931-938[article] Neurobehavioural and cognitive development in infants born to mothers with eating disorders [texte imprimé] / Manuela BARONA, Auteur ; Emma TABORELLI, Auteur ; Freya CORFIELD, Auteur ; Susan PAWLBY, Auteur ; Abigail EASTER, Auteur ; Ulrike SCHMIDT, Auteur ; Janet TREASURE, Auteur ; Nadia MICALI, Auteur . - p.931-938.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-8 (August 2017) . - p.931-938
Mots-clés : Brazelton Neonatal Behavioural Assessment Scale Bayley Scales of Infant and Toddler Development eating disorders child development Index. décimale : PER Périodiques Résumé : Introduction Although recent research has focused on the effects of maternal eating disorders (EDs) on children, little is known about the effect of maternal EDs on neurobiological outcomes in newborns and infants. This study is the first to investigate neurobehavioural regulation and cognitive development in newborns and infants of mothers with EDs. Methods Women with an active and past ED and healthy controls were recruited to a prospective longitudinal study during their first trimester or second trimester of pregnancy. Newborns and infants of mothers with ED were compared with newborns and infants of healthy controls on (a) neurobehavioural dysregulation using the Brazelton Neonatal Behavioural Assessment Scale at 8 days postpartum (active ED, n = 15; past ED, n = 20; healthy controls, n = 28); and (b) cognitive development using the Bayley Scales of Infant and Toddler Development at 1-year postpartum (active ED, n = 18; past ED, n = 19; healthy controls, n = 28). In order to maintain the largest possible sample at each time point, sample size varied across time points. Results Newborns of mothers with an active ED had worse autonomic stability when compared with newborns of healthy controls [B = −0.34 (−1.81, −0.26)]. Infants of mothers with a past ED had poorer language [B = −0.33 (−13.6, −1.9)] and motor development [B = −0.32 (−18.4, −1.3)] compared with healthy controls. Conclusions Children of mothers with ED display neurobehavioural dysregulation early after birth and poorer language and motor development at 1 year. These characteristics suggest evidence of early neurobiological markers in children at risk. Differential outcomes in children of women with active versus past ED suggest that active symptomatology during pregnancy might have an effect on physiological reactivity while cognitive characteristics might be more stable markers of risk for ED. En ligne : http://dx.doi.org/10.1111/jcpp.12736 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=316 Alexithymia may explain the relationship between autistic traits and eating disorder psychopathology / L. VUILLIER in Molecular Autism, 11 (2020)
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PermalinkCamouflaging, not sensory processing or autistic identity, predicts eating disorder symptoms in autistic adults / Siofra BRADLEY in Autism, 28-11 (November 2024)
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PermalinkEating disturbances in adults with autism spectrum disorder without intellectual disabilities / Benedetta DEMARTINI in Autism Research, 14-7 (July 2021)
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PermalinkEditorial: ‘Have you seen me lately’ – Revisiting our understanding of significant mental health disorders for children and adolescents / Daniel S. SHAW in Journal of Child Psychology and Psychiatry, 67-4 (April 2026)
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PermalinkNeurodevelopmental and psychiatric disorders in females with Turner syndrome: a population-based study / Hanna BJÖRLIN AVDIC in Journal of Neurodevelopmental Disorders, 13 (2021)
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